An integrative toolbox of word embedding research that provides: (1) a collection of pre-trained static word vectors in the .RData compressed format <https://psychbruce.github.io/WordVector_RData.pdf>; (2) a group of functions to process, analyze, and visualize word vectors; (3) a range of tests to examine conceptual associations, including the Word Embedding Association Test <doi:10.1126/science.aal4230> and the Relative Norm Distance <doi:10.1073/pnas.1720347115>, with permutation test of significance; and (4) a set of training methods to locally train (static) word vectors from text corpora, including Word2Vec <doi:10.48550/arXiv.1301.3781>, GloVe <doi:10.3115/v1/D14-1162>, and FastText <doi:10.48550/arXiv.1607.04606>.

This package provides a set of raw datasets used to create SDTM domains in pharmaversesdtm package.

This package implements data processing described in <doi:10.1126/sciadv.abk3283> to align modern differentially private data with formatting of older US Census data releases. The primary goal is to read in Census Privacy Protected Microdata Files data in a reproducible way. This includes tools for aggregating to relevant levels of geography by creating geographic identifiers which match the US Census Bureau's numbering. Additionally, there are tools for grouping race numeric identifiers into categories, consistent with OMB (Office of Management and Budget) classifications. Functions exist for downloading and linking to existing sources of privacy protected microdata.

Probabilistic factor analysis for spatially-aware dimension reduction across multi-section spatial transcriptomics data with millions of spatial locations. More details can be referred to Wei Liu, et al. (2023) <doi:10.1101/2023.07.11.548486>.

Fit a probabilistic index model as described in Thas et al, 2012: <doi:10.1111/j.1467-9868.2011.01020.x>. The interface to the modeling function has changed in this new version. The old version is still available at R-Forge.

Location- and scale-invariant Box-Cox and Yeo-Johnson power transformations allow for transforming variables with distributions distant from 0 to normality. Transformers are implemented as S4 objects. These allow for transforming new instances to normality after optimising fitting parameters on other data. A test for central normality allows for rejecting transformations that fail to produce a suitably normal distribution, independent of sample number.

This package provides a progression model for repeated measures (PMRM) is a continuous-time nonlinear mixed-effects model for longitudinal clinical trials in progressive diseases. Unlike mixed models for repeated measures (MMRMs), which estimate treatment effects as linear combinations of additive effects on the outcome scale, PMRMs characterize treatment effects in terms of the underlying disease trajectory. This framing yields clinically interpretable quantities such as average time saved and percent reduction in decline due to treatment. This package implements frequentist PMRMs by Raket (2022) <doi:10.1002/sim.9581> using RTMB by Kristensen (2016) <doi:10.18637/jss.v070.i05>.

Displays provenance graphically for provenance collected by the rdt or rdtLite packages, or other tools providing compatible PROV JSON output. The exact format of the JSON created by rdt and rdtLite is described in <https://github.com/End-to-end-provenance/ExtendedProvJson>. More information about rdtLite and associated tools is available at <https://github.com/End-to-end-provenance/> and Barbara Lerner, Emery Boose, and Luis Perez (2018), Using Introspection to Collect Provenance in R, Informatics, <doi: 10.3390/informatics5010012>.

An R package for polygenic trait analysis.

Latent class analysis and latent class regression models for polytomous outcome variables. Also known as latent structure analysis.

This package provides a collection of functions to simulate, estimate and forecast a wide range of regression based dynamic models for positive time series. This package implements the results presented in Prass, T.S.; Pumi, G.; Taufemback, C.G. and Carlos, J.H. (2025). "Positive time series regression models: theoretical and computational aspects". Computational Statistics 40, 1185â 1215. <doi:10.1007/s00180-024-01531-z>.

Automated backtesting of multiple portfolios over multiple datasets of stock prices in a rolling-window fashion. Intended for researchers and practitioners to backtest a set of different portfolios, as well as by a course instructor to assess the students in their portfolio design in a fully automated and convenient manner, with results conveniently formatted in tables and plots. Each portfolio design is easily defined as a function that takes as input a window of the stock prices and outputs the portfolio weights. Multiple portfolios can be easily specified as a list of functions or as files in a folder. Multiple datasets can be conveniently extracted randomly from different markets, different time periods, and different subsets of the stock universe. The results can be later assessed and ranked with tables based on a number of performance criteria (e.g., expected return, volatility, Sharpe ratio, drawdown, turnover rate, return on investment, computational time, etc.), as well as plotted in a number of ways with nice barplots and boxplots.

This package provides a comprehensive framework for planning and executing analyses in R. It provides a structured approach to running the same function multiple times with different arguments, executing multiple functions on the same datasets, and creating systematic analyses across multiple strata or variables. The framework is particularly useful for applying the same analysis across multiple strata (e.g., locations, age groups), running statistical methods on multiple variables (e.g., exposures, outcomes), generating multiple tables or graphs for reports, and creating systematic surveillance analyses. Key features include efficient data management, structured analysis planning, flexible execution options, built-in debugging tools, and hash-based caching.

This package provides several measures ((dis)similarity, distance/metric, correlation, entropy) for comparing two partitions of the same set of objects. The different measures can be assigned to three different classes: Pair comparison (containing the famous Jaccard and Rand indices), set based, and information theory based. Many of the implemented measures can be found in Albatineh AN, Niewiadomska-Bugaj M and Mihalko D (2006) <doi:10.1007/s00357-006-0017-z> and Meila M (2007) <doi:10.1016/j.jmva.2006.11.013>. Partitions are represented by vectors of class labels which allow a straightforward integration with existing clustering algorithms (e.g. kmeans()). The package is mostly based on the S4 object system.

Processing Chlorophyll Fluorescence & P700 Absorbance data. Four models are provided for the regression of Pi curves, which can be compared with each other in order to select the most suitable model for the data set. Control plots ensure the successful verification of each regression. Bundled output of alpha, ETRmax, Ik etc. enables fast and reliable further processing of the data.

Given a data matrix with rows representing data vectors and columns representing variables, produces a directed polytree for the underlying causal structure. Based on the algorithm developed in Chatterjee and Vidyasagar (2022) <arxiv:2209.07028>. The method is fully nonparametric, making no use of linearity assumptions, and especially useful when the number of variables is large.

The portmanteau local feature discriminant approach first identifies the local discriminant features and their differential structures, then constructs the discriminant rule by pooling the identified local features together. This method is applicable to high-dimensional matrix-variate data. See the paper by Xu, Luo and Chen (2023, <doi:10.1007/s13171-021-00255-2>).

An embedded proximal interior point quadratic programming solver, which can solve dense and sparse quadratic programs, described in Schwan, Jiang, Kuhn, and Jones (2023) <doi:10.48550/arXiv.2304.00290>. Combining an infeasible interior point method with the proximal method of multipliers, the algorithm can handle ill-conditioned convex quadratic programming problems without the need for linear independence of the constraints. The solver is written in header only C++ 14 leveraging the Eigen library for vectorized linear algebra. For small dense problems, vectorized instructions and cache locality can be exploited more efficiently. Allocation free problem updates and re-solves are also provided.

Simulating and conducting four phase 12 clinical trials with correlated binary bivariate outcomes described. Uses the Efftox (efficacy and toxicity tradeoff, <https://biostatistics.mdanderson.org/SoftwareDownload/SingleSoftware/Index/2>) and SPSO (Semi-Parametric Stochastic Ordering) models with Utility and Desirability based objective functions for dose finding.

This package provides functions to measure Alpha, Beta and Gamma Proximity to Irreplaceability. The methods for Alpha and Beta irreplaceability were first described in: Baisero D., Schuster R. & Plumptre A.J. Redefining and Mapping Global Irreplaceability. Conservation Biology 2021;1-11. <doi:10.1111/cobi.13806>.

Data files and documentation for PEDiatric vALidation oF vAriableS in TBI (PEDALFAST). The data was used in "Functional Status Scale in Children With Traumatic Brain Injury: A Prospective Cohort Study" by Bennett, Dixon, et al (2016) <doi:10.1097/PCC.0000000000000934>.

This package provides a user friendly way to create patient level prediction models using the Observational Medical Outcomes Partnership Common Data Model. Given a cohort of interest and an outcome of interest, the package can use data in the Common Data Model to build a large set of features. These features can then be used to fit a predictive model with a number of machine learning algorithms. This is further described in Reps (2017) <doi:10.1093/jamia/ocy032>.

This provides utilities for creating classed error and warning conditions based on where the error originated.

Compute bending energies, principal warps, partial warp scores, and the non-affine component of shape variation for 2D landmark configurations, as well as Mardia-Dryden distributions and self-similar distributions of landmarks, as described in Mitteroecker et al. (2020) <doi:10.1093/sysbio/syaa007>. Working examples to decompose shape variation into small-scale and large-scale components, and to decompose the total shape variation into outline and residual shape components are provided. Two landmark datasets are provided, that quantify skull morphology in humans and papionin primates, respectively from Mitteroecker et al. (2020) <doi:10.5061/dryad.j6q573n8s> and Grunstra et al. (2020) <doi:10.5061/dryad.zkh189373>.