This package provides a workflow based on machine learning methods to construct and compare single-cell gene regulatory networks (scGRN) using single-cell RNA-seq (scRNA-seq) data collected from different conditions. Uses principal component regression, tensor decomposition, and manifold alignment, to accurately identify even subtly shifted gene expression programs. See <doi:10.1016/j.patter.2020.100139> for more details.

This package provides a set of functions to estimate the controlled direct effect of treatment fixing a potential mediator to a specific value. Implements the sequential g-estimation estimator described in Vansteelandt (2009) <doi:10.1097/EDE.0b013e3181b6f4c9> and Acharya, Blackwell, and Sen (2016) <doi:10.1017/S0003055416000216> and the telescope matching estimator described in Blackwell and Strezhnev (2020) <doi:10.1111/rssa.12759>.

This package provides tools for performing Bayesian inference on epidemiological data to estimate the time-varying reproductive number and other related metrics. These methods were published in Li and White (2021) <doi:10.1371/journal.pcbi.1009210>. This package supports analyses based on aggregated case count data and individual line list data, facilitating enhanced surveillance and intervention planning for infectious diseases like COVID-19.

This package provides a collection of statistical and geometrical tools including the aligned rank transform (ART; Higgins et al. 1990 <doi:10.4148/2475-7772.1443>; Peterson 2002 <doi:10.22237/jmasm/1020255240>; Wobbrock et al. 2011 <doi:10.1145/1978942.1978963>), 2-D histograms and histograms with overlapping bins, a function for making all possible formulae within a set of constraints, amongst others.

This package provides tools to generate virtual environmental drivers with a given temporal autocorrelation, and to simulate pollen curves at annual resolution over millennial time-scales based on these drivers and virtual taxa with different life traits and niche features. It also provides the means to simulate quasi-realistic pollen-data conditions by applying simulated accumulation rates and given depth intervals between consecutive samples.

Bayesian models to estimate causal effects of biological treatments on time-to-event endpoints in clinical trials with principal strata defined by the occurrence of antidrug antibodies. The methodology is based on Frangakis and Rubin (2002) <doi:10.1111/j.0006-341x.2002.00021.x> and Imbens and Rubin (1997) <doi:10.1214/aos/1034276631>, and here adapted to a specific time-to-event setting.

This package provides functions used for graphing in multivariate contexts. These functions are designed to support produce reasonable graphs with minimal input of graphing parameters. The motivation for these functions was to support students learning multivariate concepts and R - there may be other functions and packages better-suited to practical data analysis. For details about the ellipse methods see Johnson and Wichern (2007, ISBN:9780131877153).

This package provides some function to perform posterior estimation for some distribution, with emphasis to extreme value distributions. It contains some extreme datasets, and functions that perform the runs of posterior points of the GPD and GEV distribution. The package calculate some important extreme measures like return level for each t periods of time, and some plots as the predictive distribution, and return level plots.

This package implements schemes for estimating player or team skill based on dynamic updating. Implemented methods include Elo, Glicko, Glicko-2 and Stephenson. Contains pdf documentation of a reproducible analysis using approximately two million chess matches. Also contains an Elo based method for multi-player games where the result is a placing or a score. This includes zero-sum games such as poker and mahjong.

Search for R packages on CRAN directly from the R console, based on the packages titles, short and long descriptions, or other fields. Combine multiple keywords with logical operators ('and', or'), view detailed information on any package and keep track of the latest package contributions to CRAN. If you don't want to search from the R console, use the comfortable R Studio add-in.

This package provides access to the scRNA-seq, scATAC-seq, multiome, CITE-seq and spatial transcriptomics (Visium) data generated by the tonsil cell atlas in the context of the Human Cell Atlas (HCA). The data is provided via the Bioconductor project in the form of SingleCellExperiments. Additionally, information on the whole compendium of identified cell types is provided in form of a glossary.

This package provides a collection of S4 classes, methods and functions to create and visualize business plans. Different types of cash flows can be defined, which can then be used and tabulated to create profit and loss statements, cash flow plans, investment and depreciation schedules, loan amortization schedules, etc. The methods are designed to produce handsome tables in both PDF and HTML using RMarkdown or Shiny'.

This package implements Bayesian Lasso regression using efficient Gibbs sampling algorithms, including modified versions of the Hans and Parkâ Casella (PC) samplers. Includes functions for working with the Lasso distribution, such as its density, cumulative distribution, quantile, and random generation functions, along with moment calculations. Also includes a function to compute the Mills ratio. Designed for sparse linear models and suitable for high-dimensional regression problems.

This package provides a broad collection of datasets focused on health, biomechanics, and human motion. It includes clinical, physiological, and kinematic information from diverse sources, covering aspects such as surgery outcomes, vital signs, rheumatoid arthritis, osteoarthritis, accelerometry, gait analysis, motion sensing, and biomechanics experiments. Designed for researchers, analysts, and students, the package facilitates exploration and analysis of data related to health monitoring, physical activity, and rehabilitation.

Graphical User Interface allowing to determine the concentration in the sample in CFU per mL or in number of copies per mL provided to qPCR results after with or without PMA treatment. This package is simply to use because no knowledge in R commands is necessary. A graphic represents the standard curve, and a table containing the result for each sample is created.

Quasi-Monte-Carlo algorithm for systematic generation of shock scenarios from an arbitrary multivariate elliptical distribution. The algorithm selects a systematic mesh of arbitrary fineness that approximately evenly covers an isoprobability ellipsoid in d dimensions (Flood, Mark D. & Korenko, George G. (2013) <doi:10.1080/14697688.2014.926018>). This package is the R analogy to the Matlab code published by Flood & Korenko in above-mentioned paper.

This package provides several functions and datasets for area level of Small Area Estimation under Spatial Model using Hierarchical Bayesian (HB) Method. Model-based estimators include the HB estimators based on a Spatial Fay-Herriot model with univariate normal distribution for variable of interest.The rjags package is employed to obtain parameter estimates. For the reference, see Rao and Molina (2015) <doi:10.1002/9781118735855>.

This package provides functions for the variance gamma distribution. Density, distribution and quantile functions. Functions for random number generation and fitting of the variance gamma to data. Also, functions for computing moments of the variance gamma distribution of any order about any location. In addition, there are functions for checking the validity of parameters and to interchange different sets of parameterizations for the variance gamma distribution.

The AnVIL is a cloud computing resource developed in part by the National Human Genome Research Institute. The main cloud-based genomics platform deported by the AnVIL project is Terra. The AnVILWorkflow package allows remote access to Terra implemented workflows, enabling end-user to utilize Terra/ AnVIL provided resources - such as data, workflows, and flexible/scalble computing resources - through the conventional R functions.

This package provides a collection of tools for doing various analyses of multi-state QTL data, with a focus on visualization and interpretation. The package multistateQTL contains functions which can remove or impute missing data, identify significant associations, as well as categorise features into global, multi-state or unique. The analysis results are stored in a QTLExperiment object, which is based on the SummarisedExperiment framework.

Rcpp (free of Java'/'Weka') implementation of FSelector entropy-based feature selection algorithms based on an MDL discretization (Fayyad U. M., Irani K. B.: Multi-Interval Discretization of Continuous-Valued Attributes for Classification Learning. In 13'th International Joint Conference on Uncertainly in Artificial Intelligence (IJCAI93), pages 1022-1029, Chambery, France, 1993.) <https://www.ijcai.org/Proceedings/93-2/Papers/022.pdf> with a sparse matrix support.

Easily analyze and visualize the performance of symptom checkers. This package can be used to gain comprehensive insights into the performance of single symptom checkers or the performance of multiple symptom checkers. It can be used to easily compare these symptom checkers across several metrics to gain an understanding of their strengths and weaknesses. The metrics are developed in Kopka et al. (2023) <doi:10.1177/20552076231194929>.

This is an advanced version of TDbasedUFE, which is a comprehensive package to perform Tensor decomposition based unsupervised feature extraction. In contrast to TDbasedUFE which can perform simple the feature selection and the multiomics analyses, this package can perform more complicated and advanced features, but they are not so popularly required. Only users who require more specific features can make use of its functionality.

The main application concerns to a new robust optimization package with two major contributions. The first contribution refers to the assessment of the adequacy of probabilistic models through a combination of several statistics, which measure the relative quality of statistical models for a given data set. The second one provides a general purpose optimization method based on meta-heuristics functions for maximizing or minimizing an arbitrary objective function.