Probabilistic distance clustering (PD-clustering) is an iterative, distribution-free, probabilistic clustering method. PD-clustering assigns units to a cluster according to their probability of membership under the constraint that the product of the probability and the distance of each point to any cluster center is a constant. PD-clustering is a flexible method that can be used with elliptical clusters, outliers, or noisy data. PDQ is an extension of the algorithm for clusters of different sizes. GPDC and TPDC use a dissimilarity measure based on densities. Factor PD-clustering (FPDC) is a factor clustering method that involves a linear transformation of variables and a cluster optimizing the PD-clustering criterion. It works on high-dimensional data sets.

Michel Rodange was a Luxembourguish writer and poet who lived in the 19th century. His most notable work is Rodange (1872, ISBN:1166177424), ("Renert oder de Fuuà am Frack an a Ma'nsgrëà t"), but he also wrote many more works, including Rodange, Tockert (1928) <https://www.autorenlexikon.lu/page/document/361/3614/1/FRE/index.html> ("D'Léierchen - Dem Léiweckerche säi Lidd") and Rodange, Welter (1929) <https://www.autorenlexikon.lu/page/document/361/3615/1/FRE/index.html> ("Dem Grow Sigfrid seng Goldkuommer"). This package contains three datasets, each made from the plain text versions of his works available on <https://data.public.lu/fr/datasets/the-works-in-luxembourguish-of-michel-rodange/>.

This package implements a method that aims to identify enhancers on large scale. The STARR-seq data consists of two sequencing datasets of the same targets in a specific genome. The input sequences show which regions where tested for enhancers. Significant enriched peaks i.e. a lot more sequences in one region than in the input where enhancers in the genomic DNA are, can be identified. So the approach pursued is to call peak every region in which there is a lot more (significant in a binomial model) STARR-seq signal than input signal and propose an enhancer at that very same position. Enhancers then are called weak or strong dependent of there degree of enrichment in comparison to input.

This package implements easy-to-use functions to generate 2-7 sets Venn plot in publication quality. ggVennDiagram plot Venn using well-defined geometry dataset and ggplot2. The shapes of 2-4 sets Venn use circles and ellipses, while the shapes of 4-7 sets Venn use irregular polygons (4 has both forms), which are developed and imported from another package venn. We provide internal functions to integrate shape data with user provided sets data, and calculated the geometry of every regions/intersections of them, then separately plot Venn in three components: set edges, set labels, and regions. From version 1.0, it is possible to customize these components as you demand in ordinary ggplot2 grammar.

Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, Oâ Dushlaine C, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2023) "An allelic series rare variant association test for candidate gene discovery" <doi:10.1016/j.ajhg.2023.07.001>.

This package provides tools for classical parameter estimation of adsorption isotherm models, including both linear and nonlinear forms of the Freundlich, Langmuir, and Temkin isotherms. This package allows users to fit these models to experimental data, providing parameter estimates along with fit statistics such as Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC). Error metrics are computed to evaluate model performance, and the package produces model fit plots with bootstrapped 95% confidence intervals. Additionally, it generates residual plots for diagnostic assessment of the models. Researchers and engineers in material science, environmental engineering, and chemical engineering can rigorously analyze adsorption behavior in their systems using this straightforward, non-Bayesian approach. For more details, see Harding (1907) <doi:10.2307/2987516>.

Allows to compare the goodness of fit of Benford's and Blondeau Da Silva's digit distributions in a dataset. It is used to check whether the data distribution is consistent with theoretical distributions highlighted by Blondeau Da Silva or not (through the dat.distr() function): this ideal theoretical distribution must be at least approximately followed by the data for the use of Blondeau Da Silva's model to be well-founded. It also enables to plot histograms of digit distributions, both observed in the dataset and given by the two theoretical approaches (with the digit.ditr() function). Finally, it proposes to quantify the goodness of fit via Pearson's chi-squared test (with the chi2() function).

Perform model selection using distribution and probability-based methods, including standardized AIC, BIC, and AICc. These standardized information criteria allow one to perform model selection in a way similar to the prevalent "Rule of 2" method, but formalize the method to rely on probability theory. A novel goodness-of-fit procedure for assessing linear regression models is also available. This test relies on theoretical properties of the estimated error variance for a normal linear regression model, and employs a bootstrap procedure to assess the null hypothesis that the fitted model shows no lack of fit. For more information, see Koeneman and Cavanaugh (2023) <arXiv:2309.10614>. Functionality to perform all subsets linear or generalized linear regression is also available.

Unsupervised text tokenizer allowing to perform byte pair encoding and unigram modelling. Wraps the sentencepiece library <https://github.com/google/sentencepiece> which provides a language independent tokenizer to split text in words and smaller subword units. The techniques are explained in the paper "SentencePiece: A simple and language independent subword tokenizer and detokenizer for Neural Text Processing" by Taku Kudo and John Richardson (2018) <doi:10.18653/v1/D18-2012>. Provides as well straightforward access to pretrained byte pair encoding models and subword embeddings trained on Wikipedia using word2vec', as described in "BPEmb: Tokenization-free Pre-trained Subword Embeddings in 275 Languages" by Benjamin Heinzerling and Michael Strube (2018) <http://www.lrec-conf.org/proceedings/lrec2018/pdf/1049.pdf>.

Estimates area and subarea level proportions using the Small Area Estimation (SAE) Twofold Subarea Model with a hierarchical Bayesian (HB) approach under Beta distribution. A number of simulated datasets generated for illustration purposes are also included. The rstan package is employed to estimate parameters via the Hamiltonian Monte Carlo and No U-Turn Sampler algorithm. The model-based estimators include the HB mean, the variation of the mean, and quantiles. For references, see Rao and Molina (2015) <doi:10.1002/9781118735855>, Torabi and Rao (2014) <doi:10.1016/j.jmva.2014.02.001>, Leyla Mohadjer et al.(2007) <http://www.asasrms.org/Proceedings/y2007/Files/JSM2007-000559.pdf>, Erciulescu et al.(2019) <doi:10.1111/rssa.12390>, and Yudasena (2024).

Monte Carlo simulation allows testing different conditions given to the correct structural equation models. This package runs Monte Carlo simulations under different conditions (such as sample size or normality of data). Within the package data sets can be simulated and run based on the given model. First, continuous and normal data sets are generated based on the given model. Later Fleishman's power method (1978) <DOI:10.1007/BF02293811> is used to add non-normality if exists. When data generation is completed (or when generated data sets are given) model test can also be run. Please cite as "Orçan, F. (2021). MonteCarloSEM: An R Package to Simulate Data for SEM. International Journal of Assessment Tools in Education, 8 (3), 704-713.".

This package provides functions to access data from public RESTful APIs including REST Countries API', World Bank API', and Nager.Date API', covering Mexico's economic indicators, population statistics, literacy rates, international geopolitical information and official public holidays. The package also includes curated datasets related to Mexico such as air quality monitoring stations, pollution zones, income surveys, postal abbreviations, election studies, forest productivity and demographic data by state. It supports research and analysis focused on Mexico by integrating reliable global APIs with structured national datasets drawn from open and academic sources. For more information on the APIs, see: REST Countries API <https://restcountries.com/>, World Bank API <https://datahelpdesk.worldbank.org/knowledgebase/articles/889392>, and Nager.Date API <https://date.nager.at/Api>.

Defines a major mode rjsx-mode based on js2-mode for editing JSX files. rjsx-mode extends the parser in js2-mode to support the full JSX syntax. This means you get all of the js2 features plus proper syntax checking and highlighting of JSX code blocks.

Some features that this mode adds to js2:

• Highlighting JSX tag names and attributes (using the rjsx-tag and rjsx-attr faces)

• Highlight undeclared JSX components

• Parsing the spread operator ...otherProps

• Parsing && and || in child expressions cond && <BigComponent/>

• Parsing ternary expressions toggle ? <ToggleOn /> : <ToggleOff />

Additionally, since rjsx-mode extends the js2 AST, utilities using the parse tree gain access to the JSX structure.

This package provides a metapackage that brings together a curated collection of R packages containing domain-specific datasets. It includes time series data, educational metrics, crime records, medical datasets, and oncology research data. Designed to provide researchers, analysts, educators, and data scientists with centralized access to structured and well-documented datasets, this metapackage facilitates reproducible research, data exploration, and teaching applications across a wide range of domains. Included packages: - timeSeriesDataSets': Time series data from economics, finance, energy, and healthcare. - educationR': Datasets related to education, learning outcomes, and school metrics. - crimedatasets': Datasets on global and local crime and criminal behavior. - MedDataSets': Datasets related to medicine, public health, treatments, and clinical trials. - OncoDataSets': Datasets focused on cancer research, survival, genetics, and biomarkers.

Bipartite graph-based hierarchical clustering, developed for pharmacogenomic datasets and datasets sharing the same data structure. The goal is to construct a hierarchical clustering of groups of samples based on association patterns between two sets of variables. In the context of pharmacogenomic datasets, the samples are cell lines, and the two sets of variables are typically expression levels and drug sensitivity values. For this method, sparse canonical correlation analysis from Lee, W., Lee, D., Lee, Y. and Pawitan, Y. (2011) <doi:10.2202/1544-6115.1638> is first applied to extract association patterns for each group of samples. Then, a nuclear norm-based dissimilarity measure is used to construct a dissimilarity matrix between groups based on the extracted associations. Finally, hierarchical clustering is applied.

Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (http://www.synergyfinder.org) for users who prefer graphical user interface.

R's sf package ships with self-contained GDAL executables, including a bare bones interface to several GDAL'-related utility programs collectively known as the GDAL utilities'. For each of those utilities, this package provides an R wrapper whose formal arguments closely mirror those of the GDAL command line interface. The utilities operate on data stored in files and typically write their output to other files. Therefore, to process data stored in any of R's more common spatial formats (i.e. those supported by the sf and terra packages), first write them to disk, then process them with the package's wrapper functions before reading the outputted results back into R. GDAL function arguments introduced in GDAL version 3.5.2 or earlier are supported.

We designed this package to provides several functions for area and subarea level of small area estimation under Twofold Subarea Level Model using hierarchical Bayesian (HB) method with Univariate Normal distribution for variables of interest. Some dataset simulated by a data generation are also provided. The rjags package is employed to obtain parameter estimates using Gibbs Sampling algorithm. Model-based estimators involves the HB estimators which include the mean, the variation of mean, and the quantile. For the reference, see Rao and Molina (2015) <doi:10.1002/9781118735855>, Torabi and Rao (2014) <doi:10.1016/j.jmva.2014.02.001>, Leyla Mohadjer et al.(2007) <http://www.asasrms.org/Proceedings/y2007/Files/JSM2007-000559.pdf>, and Erciulescu et al.(2019) <doi:10.1111/rssa.12390>.

An R API providing access to a relational database with macroeconomic data for Africa. The database contains >700 macroeconomic time series from mostly international sources, grouped into 50 macroeconomic and development-related topics. Series are carefully selected on the basis of data coverage for Africa, frequency, and relevance to the macro-development context. The project is part of the Kiel Institute Africa Initiative <https://www.ifw-kiel.de/institute/initiatives/kiel-institute-africa-initiative/>, which, amongst other things, aims to develop a parsimonious database with highly relevant indicators to monitor macroeconomic developments in Africa, accessible through a fast API and a web-based platform at <https://africamonitor.ifw-kiel.de/>. The database is maintained at the Kiel Institute for the World Economy <https://www.ifw-kiel.de/>.

Simulation-based sensitivity analysis for causal mediation studies. It numerically and graphically evaluates the sensitivity of causal mediation analysis results to the presence of unmeasured pretreatment confounding. The proposed method has primary advantages over existing methods. First, using an unmeasured pretreatment confounder conditional associations with the treatment, mediator, and outcome as sensitivity parameters, the method enables users to intuitively assess sensitivity in reference to prior knowledge about the strength of a potential unmeasured pretreatment confounder. Second, the method accurately reflects the influence of unmeasured pretreatment confounding on the efficiency of estimation of the causal effects. Third, the method can be implemented in different causal mediation analysis approaches, including regression-based, simulation-based, and propensity score-based methods. It is applicable to both randomized experiments and observational studies.

Fast, optimal, and reproducible weighted univariate clustering by dynamic programming. Four problems are solved, including univariate k-means (Wang & Song 2011) <doi:10.32614/RJ-2011-015> (Song & Zhong 2020) <doi:10.1093/bioinformatics/btaa613>, k-median, k-segments, and multi-channel weighted k-means. Dynamic programming is used to minimize the sum of (weighted) within-cluster distances using respective metrics. Its advantage over heuristic clustering in efficiency and accuracy is pronounced when there are many clusters. Multi-channel weighted k-means groups multiple univariate signals into k clusters. An auxiliary function generates histograms adaptive to patterns in data. This package provides a powerful set of tools for univariate data analysis with guaranteed optimality, efficiency, and reproducibility, useful for peak calling on temporal, spatial, and spectral data.

Estimates the precision of transdimensional Markov chain Monte Carlo (MCMC) output, which is often used for Bayesian analysis of models with different dimensionality (e.g., model selection). Transdimensional MCMC (e.g., reversible jump MCMC) relies on sampling a discrete model-indicator variable to estimate the posterior model probabilities. If only few switches occur between the models, precision may be low and assessment based on the assumption of independent samples misleading. Based on the observed transition matrix of the indicator variable, the method of Heck, Overstall, Gronau, & Wagenmakers (2019, Statistics & Computing, 29, 631-643) <doi:10.1007/s11222-018-9828-0> draws posterior samples of the stationary distribution to (a) assess the uncertainty in the estimated posterior model probabilities and (b) estimate the effective sample size of the MCMC output.

Objective Bayesian inference procedures for the parameters of the multivariate random effects model with application to multivariate meta-analysis. The posterior for the model parameters, namely the overall mean vector and the between-study covariance matrix, are assessed by constructing Markov chains based on the Metropolis-Hastings algorithms as developed in Bodnar and Bodnar (2021) (<arXiv:2104.02105>). The Metropolis-Hastings algorithm is designed under the assumption of the normal distribution and the t-distribution when the Berger and Bernardo reference prior and the Jeffreys prior are assigned to the model parameters. Convergence properties of the generated Markov chains are investigated by the rank plots and the split hat-R estimate based on the rank normalization, which are proposed in Vehtari et al. (2021) (<DOI:10.1214/20-BA1221>).

This package provides a collection of user-submitted functions to aid in the analysis of hydrological data, particularly for users in Canada. The functions focus on the use of Canadian data sets, and are suited to Canadian hydrology, such as the important cold region hydrological processes and will work with Canadian hydrological models. The functions are grouped into several themes, currently including Statistical hydrology, Basic data manipulations, Visualization, and Spatial hydrology. Functions developed by the Floodnet project are also included. CSHShydRology has been developed with the assistance of the Canadian Society for Hydrological Sciences (CSHS) which is an affiliated society of the Canadian Water Resources Association (CWRA). As of version 1.2.6, functions now fail gracefully when attempting to download data from a url which is unavailable.