Allows practitioners and researchers a wholesale approach for deriving magnitude-based inferences from raw data. A major goal of mbir is to programmatically detect appropriate statistical tests to run in lieu of relying on practitioners to determine correct stepwise procedures independently.

This package provides a novel mediation analysis approach to address zero-inflated mediators containing true zeros and false zeros. See Jiang et al (2023) "A Novel Causal Mediation Analysis Approach for Zero-Inflated Mediators" <arXiv:2301.10064> for more details.

Efficient procedures for computing a new Multi-Class Sparse Discriminant Analysis method that estimates all discriminant directions simultaneously. It is an implementation of the work proposed by Mai, Q., Yang, Y., and Zou, H. (2019) <doi:10.5705/ss.202016.0117>.

This package creates a spectroscopy guideline with a highly accurate prediction model for soil properties using machine learning or deep learning algorithms such as LASSO, Random Forest, Cubist, etc., and decide which algorithm generates the best model for different soil types.

Package to select best model among several linear and nonlinear models. The main function uses the gnls() function from the nlme package to fit the data to nine regression models, named: "linear", "quadratic", "cubic", "logistic", "exponential", "power", "monod", "haldane", "logit".

Computes the pdf, cdf, quantile function, hazard function and generating random numbers for Odd log-logistic family (OLL-G). This family have been developed by different authors in the recent years. See Alizadeh (2019) <doi:10.31801/cfsuasmas.542988> for example.

Creates, fits and samples Pair-Copula Bayesian networks (PCBN) under some restrictions on the underlying Directed Acyclic Graph (DAG), that is, no active cycles nor interfering v-structures, following Derumigny, Horsman and Kurowicka (2025) <doi:10.48550/arXiv.2510.03518>.

Estimating parameters of site clusters on 2D & 3D square lattice with various lattice sizes, relative fractions of open sites (occupation probability), iso- & anisotropy, von Neumann & Moore (1,d)-neighborhoods, described by Moskalev P.V. et al. (2011) <arXiv:1105.2334v1>.

Token-Oriented Object Notation (TOON) is a compact, human-readable serialization format designed for passing structured data to Large Language Models with significantly reduced token usage. It's intended for LLM input as a lossless, drop-in representation of JSON data.

The tinytest package offers a light-weight zero-dependency unit-testing framework to which this package adds support via the diffobj package for diff'-style textual comparison of R objects, as well as via tinysnapshot package for visual differences in plots.

This package provides functions that can be used to calculate time-dependent state and parameter sensitivities for both continuous- and discrete-time deterministic models. See Ng et al. (2023) <doi:10.1086/726143> for more information about time-dependent sensitivity analysis.

This package provides a collection of functions for visualizing,exploring and annotating genetic association results.Association results from multiple traits can be viewed simultaneously along with gene annotation, over the entire genome (Manhattan plot) or in the more detailed regional view.

The purpose of this package is to provide methods to interpret multiple linear regression and canonical correlation results including beta weights,structure coefficients, validity coefficients, product measures, relative weights, all-possible-subsets regression, dominance analysis, commonality analysis, and adjusted effect sizes.

This package provides a two-part zero-inflated Beta regression model with random effects (ZIBR) for testing the association between microbial abundance and clinical covariates for longitudinal microbiome data. Eric Z. Chen and Hongzhe Li (2016) <doi:10.1093/bioinformatics/btw308>.

The Rcpp package provides R functions as well as C++ classes which offer a seamless integration of R and C++. Many R data types and objects can be mapped back and forth to C++ equivalents which facilitates both writing of new code as well as easier integration of third-party libraries. Documentation about Rcpp is provided by several vignettes included in this package, via the Rcpp Gallery site at <http://gallery.rcpp.org>, the paper by Eddelbuettel and Francois (2011, JSS), and the book by Eddelbuettel (2013, Springer); see citation("Rcpp") for details on these last two.

Efficient framework for ridge redundancy analysis (rrda), tailored for high-dimensional omics datasets where the number of predictors exceeds the number of samples. The method leverages Singular Value Decomposition (SVD) to avoid direct inversion of the covariance matrix, enhancing scalability and performance. It also introduces a memory-efficient storage strategy for coefficient matrices, enabling practical use in large-scale applications. The package supports cross-validation for selecting regularization parameters and reduced-rank dimensions, making it a robust and flexible tool for multivariate analysis in omics research. Please refer to our article (Yoshioka et al., 2025) for more details.

This package provides functions for reading array comparative genomic hybridization (aCGH) data from image analysis output files and clone information files, creation of aCGH objects for storing these data. Basic methods are accessing/replacing, subsetting, printing and plotting aCGH objects.

R-scape discovers RNA secondary structure consensus elements. These elements include riboswitches and ribozymes. It utilizes probabilistic modeling of sequence alignments, explicitly considering folding dependencies. The tool enables the de novo search for new structural elements and facilitates comparative analysis of known RNA families.

This package generates well-known integer sequences. The gmp package is adopted for computing with arbitrarily large numbers. Every function has a hyperlink to its corresponding item in the On-Line Encyclopedia of Integer Sequences (OEIS) in the function help page.

This package provides tools for visualizing, smoothing and comparing receiver operating characteristic (ROC curves). The area under the curve (AUC) can be compared with statistical tests based on U-statistics or bootstrap. Confidence intervals can be computed for (p)AUC or ROC curves.

This package provides S3 classes and methods to create and work with year-quarter, year-month and year-isoweek vectors. Basic arithmetic operations (such as adding and subtracting) are supported, as well as formatting and converting to and from standard R date types.

Package that implements the FGGA algorithm. This package provides a hierarchical ensemble method based ob factor graphs for the consistent cross-ontology annotation of protein coding genes. FGGA embodies elements of predicate logic, communication theory, supervised learning and inference in graphical models.

Package to integrate methylation and expression data. It can also perform methylation or expression analysis alone. Several plotting functionalities are included as well as a new region analysis based on redundancy analysis. Effect of SNPs on a region can also be estimated.

This package automates analysis workflow for Thermal Shift Analysis (TSA) data. Processing, analyzing, and visualizing data through both shiny applications and command lines. Package aims to simplify data analysis and offer front to end workflow, from raw data to multiple trial analysis.