This package provides a toolbox for writing knitr', Sweave or other LaTeX'- or markdown'-based reports and to prettify the output of various estimated models.

Likelihood based population viability analysis in the presence of observation error and missing data. The package can be used to fit, compare, predict, and forecast various growth model types using data cloning.

This package performs sensitivity analysis for publication bias in meta-analyses (per Mathur & VanderWeele, 2020 [<doi:10.31219/osf.io/s9dp6>]). These analyses enable statements such as: "For publication bias to shift the observed point estimate to the null, significant results would need to be at least 30-fold more likely to be published than negative or nonsignificant results." Comparable statements can be made regarding shifting to a chosen non-null value or shifting the confidence interval. Provides a worst-case meta-analytic point estimate under maximal publication bias obtained simply by conducting a standard meta-analysis of only the negative and "nonsignificant" studies.

Using Electronic Health Record (EHR) is difficult because most of the time the true characteristic of the patient is not available. Instead we can retrieve the International Classification of Disease code related to the disease of interest or we can count the occurrence of the Unified Medical Language System. None of them is the true phenotype which needs chart review to identify. However chart review is time consuming and costly. PheVis is an algorithm which is phenotyping (i.e identify a characteristic) at the visit level in an unsupervised fashion. It can be used for chronic or acute diseases. An example of how to use PheVis is available in the vignette. Basically there are two functions that are to be used: `train_phevis()` which trains the algorithm and `test_phevis()` which get the predicted probabilities. The detailed method is described in preprint by Ferté et al. (2020) <doi:10.1101/2020.06.15.20131458>.

This package provides a PNAS'-alike style for rmarkdown', derived from the Proceedings of the National Academy of Sciences of the United States of America ('PNAS') LaTeX style, and adapted for use with markdown and pandoc'.

Construct parser combinator functions, higher order functions that parse input. Construction of such parsers is transparent and easy. Their main application is the parsing of structured text files like those generated by laboratory instruments. Based on a paper by Hutton (1992) <doi:10.1017/S0956796800000411>.

Simplify your portfolio optimization process by applying a contemporary modeling way to model and solve your portfolio problems. While most approaches and packages are rather complicated this one tries to simplify things and is agnostic regarding risk measures as well as optimization solvers. Some of the methods implemented are described by Konno and Yamazaki (1991) <doi:10.1287/mnsc.37.5.519>, Rockafellar and Uryasev (2001) <doi:10.21314/JOR.2000.038> and Markowitz (1952) <doi:10.1111/j.1540-6261.1952.tb01525.x>.

Implementation of the Pearson distribution system, including full support for the (d,p,q,r)-family of functions for probability distributions and fitting via method of moments and maximum likelihood method.

Create random passwords of letters, numbers and punctuation.

Fit a model with potentially many linear and smooth predictors. Interaction effects can also be quantified. Variable selection is done using penalisation. For l1-type penalties we use iterative steps alternating between using linear predictors (lasso) and smooth predictors (generalised additive model).

This package implements estimation and testing procedures for evaluating an intermediate biomarker response as a principal surrogate of a clinical response to treatment (i.e., principal stratification effect modification analysis), as described in Juraska M, Huang Y, and Gilbert PB (2020), Inference on treatment effect modification by biomarker response in a three-phase sampling design, Biostatistics, 21(3): 545-560 <doi:10.1093/biostatistics/kxy074>. The methods avoid the restrictive placebo structural risk modeling assumption common to past methods and further improve robustness by the use of nonparametric kernel smoothing for biomarker density estimation. A randomized controlled two-group clinical efficacy trial is assumed with an ordered categorical or continuous univariate biomarker response measured at a fixed timepoint post-randomization and with a univariate baseline surrogate measure allowed to be observed in only a subset of trial participants with an observed biomarker response (see the flexible three-phase sampling design in the paper for details). Bootstrap-based procedures are available for pointwise and simultaneous confidence intervals and testing of four relevant hypotheses. Summary and plotting functions are provided for estimation results.

Google Pathways Language Model 2 (PaLM 2) as a coding and writing assistant designed for R'. With a range of functions, including natural language processing and coding optimization, to assist R developers in simplifying tedious coding tasks and content searching.

Routines for PLS-based genomic analyses, implementing PLS methods for classification with microarray data and prediction of transcription factor activities from combined ChIP-chip analysis. The >=1.2-1 versions include two new classification methods for microarray data: GSIM and Ridge PLS. The >=1.3 versions includes a new classification method combining variable selection and compression in logistic regression context: logit-SPLS; and an adaptive version of the sparse PLS.

Measures real distances in pictures. With PDM() function, you can choose one *.jpg file, select the measure in mm of scale, starting and and finishing point in the graphical scale, the name of the measure, and starting and and finishing point of the measures. After, ask the user for a new measure.

It allows the user to determine sample sizes, select probabilistic samples, make estimates of different parameters for the total finite population and in studio domains, using the main design drawings.

This package produces odds ratio analyses with comprehensive reporting tools. Generates plots, summary tables, and diagnostic checks for logistic regression models fitted with glm() using binomial family. Provides visualisation methods, formatted reporting tables via gt', and tools to assess logistic regression model assumptions.

Hidden Markov Models are useful for modeling sequential data. This package provides several functions implemented in C++ for explaining the algorithms used for Hidden Markov Models (forward, backward, decoding, learning).

This package implements a phylogeny-aware Bayesian graphical modeling framework for microbial network inference using a shrinkage precision estimator guided by a phylogenetic kernel, with optional hyperparameter-ensemble edge reliability analysis.

Tailoring the optimal biomarker(s) for disease screening or diagnosis based on subjects individual characteristics.

Perform sample size, power calculation and subsequent analysis for Immuno-oncology (IO) trials composed of responders and non-responders.

Comprehensive toolkit for generating various numerical features of protein sequences described in Xiao et al. (2015) <DOI:10.1093/bioinformatics/btv042>. For full functionality, the software ncbi-blast+ is needed, see <https://blast.ncbi.nlm.nih.gov/doc/blast-help/downloadblastdata.html> for more information.

Quantification of variation in organismal color patterns as obtained from image data. Patternize defines homology between pattern positions across images either through fixed landmarks or image registration. Pattern identification is performed by categorizing the distribution of colors using RGB thresholds or image segmentation.

This package provides tools for simplifying the creation and management of data structures suitable for dealing with policy portfolios, that is, two-dimensional spaces of policy instruments and policy targets. The package also allows to generate measures of portfolio characteristics and facilitates their visualization.

This package provides tools from the domain of graph theory can be used to quantify the complexity and vulnerability to failure of a software package. That is the guiding philosophy of this package. pkgnet provides tools to analyze the dependencies between functions in an R package and between its imported packages. See the pkgnet website for vignettes and other supplementary information.