Sample size calculations in causal inference with observational data are increasingly desired. This package is a tool to calculate sample size under prespecified power with minimal summary quantities needed.

Optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix. This package was developed for pharmacometric problems, and examples and predefined models are available for these types of systems. The methods are described in Nyberg et al. (2012) <doi:10.1016/j.cmpb.2012.05.005>, and Foracchia et al. (2004) <doi:10.1016/S0169-2607(03)00073-7>.

This package provides a network-based systems biology tool for flexible identification of phenotype-specific subpathways in the cancer gene expression data with multiple categories (such as multiple subtype or developmental stages of cancer). Subtype Set Enrichment Analysis (SubSEA) and Dynamic Changed Subpathway Analysis (DCSA) are developed to flexible identify subtype specific and dynamic changed subpathways respectively. The operation modes include extraction of subpathways from biological pathways, inference of subpathway activities in the context of gene expression data, identification of subtype specific subpathways with SubSEA, identification of dynamic changed subpathways associated with the cancer developmental stage with DCSA, and visualization of the activities of resulting subpathways by using box plots and heat maps. Its capabilities render the tool could find the specific abnormal subpathways in the cancer dataset with multi-phenotype samples.

This package implements the Bayesian hierarchical model described by Wheldon, Raftery, Clark and Gerland (see: <doi:10.1080/01621459.2012.737729>) for simultaneously estimating age-specific population counts, fertility rates, mortality rates and net international migration flows, at the national level.

Static code analyses for R packages using the external code-tagging libraries ctags and gtags'. Static analyses enable packages to be analysed very quickly, generally a couple of seconds at most. The package also provides access to a database generating by applying the main function to the full CRAN archive, enabling the statistical properties of any package to be compared with all other CRAN packages.

Examples for integrating package perry for prediction error estimation into regression models.

This package provides functions for causal structure learning and causal inference using graphical models. The main algorithms for causal structure learning are PC (for observational data without hidden variables), FCI and RFCI (for observational data with hidden variables), and GIES (for a mix of data from observational studies (i.e. observational data) and data from experiments involving interventions (i.e. interventional data) without hidden variables). For causal inference the IDA algorithm, the Generalized Backdoor Criterion (GBC), the Generalized Adjustment Criterion (GAC) and some related functions are implemented. Functions for incorporating background knowledge are provided.

Implementation of the Partitioned Local Depth (PaLD) approach which provides a measure of local depth and the cohesion of a point to another which (together with a universal threshold for distinguishing strong and weak ties) may be used to reveal local and global structure in data, based on methods described in Berenhaut, Moore, and Melvin (2022) <doi:10.1073/pnas.2003634119>. No extraneous inputs, distributional assumptions, iterative procedures nor optimization criteria are employed. This package includes functions for computing local depths and cohesion as well as flexible functions for plotting community networks and displays of cohesion against distance.

R's implementation of the JavaScript library path-to-regexp', it aims to provide R web frameworks features such as parameter handling among other URL path utilities.

Some functions at the intersection of dplyr and purrr that formerly lived in purrr'.

Most price indexes are made with a two-step procedure, where period-over-period elementary indexes are first calculated for a collection of elementary aggregates at each point in time, and then aggregated according to a price index aggregation structure. These indexes can then be chained together to form a time series that gives the evolution of prices with respect to a fixed base period. This package contains a collection of functions that revolve around this work flow, making it easy to build standard price indexes, and implement the methods described by Balk (2008, <doi:10.1017/CBO9780511720758>), von der Lippe (2007, <doi:10.3726/978-3-653-01120-3>), and the CPI manual (2020, <doi:10.5089/9781484354841.069>) for bilateral price indexes.

This package implements a general framework for creating dependency graphs using projection as introduced in Fan, Feng and Xia (2019)<arXiv:1501.01617>. Both lasso and sparse additive model projections are implemented. Both Pearson correlation and distance covariance options are available to generate the graph.

An R-package-version of an open online science-based personality test from <https://openpsychometrics.org/tests/IPIP-BFFM/>, providing a better-designed interface and a more detailed report. The core command launch_test() opens a personality test in your browser, and generates a report after you click "Submit". In this report, your results are compared with other people's, to show what these results mean. Other people's data is from <https://openpsychometrics.org/_rawdata/BIG5.zip>.

Enables direct cloud access to health care decision models hosted on the PRISM server of the Peer Models Network.

This package provides a comprehensive and curated collection of datasets related to the lungs, respiratory system, and associated diseases. This package includes epidemiological, clinical, experimental, and simulated datasets on conditions such as lung cancer, asthma, Chronic Obstructive Pulmonary Disease (COPD), tuberculosis, whooping cough, pneumonia, influenza, and other respiratory illnesses. It is designed to support data exploration, statistical modeling, teaching, and research in pulmonary medicine, public health, environmental epidemiology, and respiratory disease surveillance.

This package provides tools for the design of prospective studies using Personalised Synthetic Controls. Can be used in either single arm or randomised studies.

Sequential Monte Carlo (SMC) inference for fully Bayesian Gaussian process (GP) regression and classification models by particle learning (PL) following Gramacy & Polson (2011) <doi:10.48550/arXiv.0909.5262>. The sequential nature of inference and the active learning (AL) hooks provided facilitate thrifty sequential design (by entropy) and optimization (by improvement) for classification and regression models, respectively. This package essentially provides a generic PL interface, and functions (arguments to the interface) which implement the GP models and AL heuristics. Functions for a special, linked, regression/classification GP model and an integrated expected conditional improvement (IECI) statistic provide for optimization in the presence of unknown constraints. Separable and isotropic Gaussian, and single-index correlation functions are supported. See the examples section of ?plgp and demo(package="plgp") for an index of demos.

Procedures for testing for group-wide signal in clusters of variables. Tests can be performed for single groups in isolation (univariate) or multiple groups together (multivariate). Specific tests include the exact and approximate (un)selective likelihood ratio tests described in Reid et al (2015), the selective F test and marginal screening prototype test of Reid and Tibshirani (2015). User may pre-specify columns to be included in prototype formation, or allow the function to select them itself. A mixture of these two is also possible. Any variable selection is accounted for using the selective inference framework. Options for non-sampling and hit-and-run null reference distributions.

Graphical methods testing multivariate normality assumption. Methods including assessing score function, and moment generating functions,independent transformations and linear transformations. For more details see Tran (2024),"Contributions to Multivariate Data Science: Assessment and Identification of Multivariate Distributions and Supervised Learning for Groups of Objects." , PhD thesis, <https://our.oakland.edu/items/c8942577-2562-4d2f-8677-cb8ec0bf6234>.

This package provides a set of Study Data Tabulation Model (SDTM) datasets from the Clinical Data Interchange Standards Consortium (CDISC) pilot project used for testing and developing Analysis Data Model (ADaM) datasets inside the pharmaverse family of packages. SDTM dataset specifications are described in the CDISC SDTM implementation guide, accessible by creating a free account on <https://www.cdisc.org/>.

This package provides a set of Analysis Data Model (ADaM) datasets constructed using the Study Data Tabulation Model (SDTM) datasets contained in the pharmaversesdtm package and the template scripts from the admiral family of packages. ADaM dataset specifications are described in the CDISC ADaM implementation guide, accessible by creating a free account on <https://www.cdisc.org/>.

An implementation of the one-step privacy-protecting method for estimating the overall and site-specific hazard ratios using inverse probability weighted Cox models in distributed data network studies, as proposed by Shu, Yoshida, Fireman, and Toh (2019) <doi: 10.1177/0962280219869742>. This method only requires sharing of summary-level riskset tables instead of individual-level data. Both the conventional inverse probability weights and the stabilized weights are implemented.

The base R data.frame, like any vector, is copied upon modification. This behavior is at odds with that of GUIs and interactive graphics. To rectify this, plumbr provides a mutable, dynamic tabular data model. Models may be chained together to form the complex plumbing necessary for sophisticated graphical interfaces. Also included is a general framework for linking datasets; an typical use case would be a linked brush.

This package provides functions for constructing dashboards for business process monitoring. Building on the event log objects class from package bupaR'. Allows the use to assemble custom shiny dashboards based on process data.