Estimate the correlation between two NIfTI images across random parcellations of the images (Fortea et al., under review). This approach overcomes the problems of both voxel-based correlations (neighbor voxels may be spatially dependent) and atlas-based correlations (the correlation may depend on the atlas used).

Digital map data of Japan for choropleth mapping, including a circle cartogram.

Designed to automate the calculation of Emergency Medical Service (EMS) quality metrics, nemsqar implements measures defined by the National EMS Quality Alliance (NEMSQA). By providing reliable, evidence-based quality assessments, the package supports EMS agencies, healthcare providers, and researchers in evaluating and improving patient outcomes. Users can find details on all approved NEMSQA measures at <https://www.nemsqa.org/measures>. Full technical specifications, including documentation and pseudocode used to develop nemsqar', are available on the NEMSQA website after creating a user profile at <https://www.nemsqa.org>.

This package provides functions to compute the non-negative garrote estimator as proposed by Breiman (1995) <https://www.jstor.org/stable/1269730> with the penalized initial estimators extension as proposed by Yuan and Lin (2007) <https://www.jstor.org/stable/4623260>.

Systematically creates and modifies NONMEM(R) control streams. Harvests NONMEM output, builds run logs, creates derivative data, generates diagnostics. NONMEM (ICON Development Solutions <https://www.iconplc.com/>) is software for nonlinear mixed effects modeling. See package?nonmemica'.

This package provides a collection of statistical tools for objective (non-supervised) applications of the Regional Frequency Analysis methods in hydrology. The package refers to the index-value method and, more precisely, helps the hydrologist to: (1) regionalize the index-value; (2) form homogeneous regions with similar growth curves; (3) fit distribution functions to the empirical regional growth curves. Most of the methods are those described in the Flood Estimation Handbook (Centre for Ecology & Hydrology, 1999, ISBN:9781906698003). Homogeneity tests from Hosking and Wallis (1993) <doi:10.1029/92WR01980> and Viglione et al. (2007) <doi:10.1029/2006WR005095> are available.

Model-based clustering of high-dimensional non-negative data that follow Generalized Negative Binomial distribution. All functions in this package applies to either continuous or integer data. Correlation between variables are allowed, while samples are assumed to be independent.

Collection of functions for fast manipulation, handling, and analysis of large-scale networks based on family and social data. Functions are utility functions used to manipulate data in three "formats": sparse adjacency matrices, pedigree trio family data, and pedigree family data. When possible, the functions should be able to handle millions of data points quickly for use in combination with data from large public national registers and databases. Kenneth Lange (2003, ISBN:978-8181281135).

Researchers often want to evaluate whether there is a negligible relationship among variables. The negligible package provides functions that are useful for conducting negligible effect testing (also called equivalence testing). For example, there are functions for evaluating the equivalence of means or the presence of a negligible association (correlation or regression). Beribisky, N., Mara, C., & Cribbie, R. A. (2020) <doi:10.20982/tqmp.16.4.p424>. Beribisky, N., Davidson, H., Cribbie, R. A. (2019) <doi:10.7717/peerj.6853>. Shiskina, T., Farmus, L., & Cribbie, R. A. (2018) <doi:10.20982/tqmp.14.3.p167>. Mara, C. & Cribbie, R. A. (2017) <doi:10.1080/00220973.2017.1301356>. Counsell, A. & Cribbie, R. A. (2015) <doi:10.1111/bmsp.12045>. van Wieringen, K. & Cribbie, R. A. (2014) <doi:10.1111/bmsp.12015>. Goertzen, J. R. & Cribbie, R. A. (2010) <doi:10.1348/000711009x475853>. Cribbie, R. A., Gruman, J. & Arpin-Cribbie, C. (2004) <doi:10.1002/jclp.10217>.

This package provides tools for the structured processing of PET neuroimaging data in preparation for the estimation of Simultaneous Confidence Corridors (SCCs) for one-group, two-group, or single-patient vs group comparisons. The package facilitates PET image loading, data restructuring, integration into a Functional Data Analysis framework, contour extraction, identification of significant results, and performance evaluation. It bridges established packages (e.g., oro.nifti') with novel statistical methodologies (e.g., ImageSCC') and enables reproducible analysis pipelines, including comparison with Statistical Parametric Mapping ('SPM').

This package provides methods to reduce confounding bias from unmeasured confounders in observational studies of vaccine efficacy using negative control outcomes.

Nested loop cross validation for classification purposes for misclassification error rate estimation. The package supports several methodologies for feature selection: random forest, Student t-test, limma, and provides an interface to the following classification methods in the MLInterfaces package: linear, quadratic discriminant analyses, random forest, bagging, prediction analysis for microarray, generalized linear model, support vector machine (svm and ksvm). Visualizations to assess the quality of the classifier are included: plot of the ranks of the features, scores plot for a specific classification algorithm and number of features, misclassification rate for the different number of features and classification algorithms tested and ROC plot. For further details about the methodology, please check: Markus Ruschhaupt, Wolfgang Huber, Annemarie Poustka, and Ulrich Mansmann (2004) <doi:10.2202/1544-6115.1078>.

Nonparametric (and semiparametric) kernel methods that seamlessly handle a mix of continuous, unordered, and ordered factor data types. This package is a parallel implementation of the np package based on the MPI specification that incorporates the Rmpi package (Hao Yu <hyu@stats.uwo.ca>) with minor modifications and we are extremely grateful to Hao Yu for his contributions to the R community. We would like to gratefully acknowledge support from the Natural Sciences and Engineering Research Council of Canada (NSERC, <https://www.nserc-crsng.gc.ca/>), the Social Sciences and Humanities Research Council of Canada (SSHRC, <https://www.sshrc-crsh.gc.ca/>), and the Shared Hierarchical Academic Research Computing Network (SHARCNET, <https://sharcnet.ca/>). We would also like to acknowledge the contributions of the GNU GSL authors. In particular, we adapt the GNU GSL B-spline routine gsl_bspline.c adding automated support for quantile knots (in addition to uniform knots), providing missing functionality for derivatives, and for extending the splines beyond their endpoints.

Given a network (e.g. a food web), estimates several network indices. These include: Ascendency network indices, Direct and indirect dependencies, Effective measures, Environ network indices, General network indices, Pathway analysis, Network uncertainty indices and constraint efficiencies and the trophic level and omnivory indices of food webs.

An implementation of a Neural Network using the Levenberg-Marquardt optimization from minpack.lm', ideal for small datasets. For more details see Moré (1978) <doi:10.1007/BFb0067700>.

An implementation of the Nonparametric Predictive Inference approach in R. It provides tools for quantifying uncertainty via lower and upper probabilities. It includes useful functions for pairwise and multiple comparisons: comparing two groups with and without terminated tails, selecting the best group, selecting the subset of best groups, selecting the subset including the best group.

Indices, heuristics, simulations and strategies to help determine the number of factors/components to retain in exploratory factor analysis and principal component analysis.

This package provides efficient implementation of the Narrowest-Over-Threshold methodology for detecting an unknown number of change-points occurring at unknown locations in one-dimensional data following deterministic signal + noise model. Currently implemented scenarios are: piecewise-constant signal, piecewise-constant signal with a heavy-tailed noise, piecewise-linear signal, piecewise-quadratic signal, piecewise-constant signal and with piecewise-constant variance of the noise. For details, see Baranowski, Chen and Fryzlewicz (2019) <doi:10.1111/rssb.12322>.

Nonparametric methods for smoothing regression function data with change-points, utilizing range kernels for iterative and anisotropic smoothing methods. For further details, see the paper by John R.J. Thompson (2024) <doi:10.1080/02664763.2024.2352759>.

Includes functions and examples to compute NEAT, the Network Enrichment Analysis Test described in Signorelli et al. (2016, <DOI:10.1186/s12859-016-1203-6>).

This is a pure dummy interfaces package which mirrors MsSparkUtils APIs <https://learn.microsoft.com/en-us/azure/synapse-analytics/spark/microsoft-spark-utilities?pivots=programming-language-r> of Azure Synapse Analytics <https://learn.microsoft.com/en-us/azure/synapse-analytics/> for R users, customer of Azure Synapse can download this package from CRAN for local development.

Network trees recursively partition the data with respect to covariates. Two network tree algorithms are available: model-based trees based on a multivariate normal model and nonparametric trees based on covariance structures. After partitioning, correlation-based networks (psychometric networks) can be fit on the partitioned data. For details see Jones, Mair, Simon, & Zeileis (2020) <doi:10.1007/s11336-020-09731-4>.

This package provides functions for Bayesian analysis of data from randomized experiments with non-compliance. The functions are based on the models described in Imbens and Rubin (1997) <doi:10.1214/aos/1034276631>. Currently only two types of outcome models are supported: binary outcomes and normally distributed outcomes. Models can be fit with and without the exclusion restriction and/or the strong access monotonicity assumption. Models are fit using the data augmentation algorithm as described in Tanner and Wong (1987) <doi:10.2307/2289457>.

This package provides a collection of dynamic network data sets from various sources and multiple authors represented as networkDynamic'-formatted objects.