This is a package for saving SummarizedExperiments into file artifacts, and loading them back into memory. This is a more portable alternative to serialization of such objects into RDS files. Each artifact is associated with metadata for further interpretation; downstream applications can enrich this metadata with context-specific properties.
This package provides an implementation of the BRGE's (Bioinformatic Research Group in Epidemiology from Center for Research in Environmental Epidemiology) MultiDataSet and ResultSet. MultiDataSet is designed for integrating multi omics data sets and ResultSet is a container for omics results. This package contains base classes for MEAL and rexposome packages.
Data package providing example DNA methylation files used in the DMRsegal vignette and examples. Includes a sorted beta matrix as a tab-delimited, bgzip-compressed file and a matching phenotype table. The data contains 10 healthy and 10 cancer samples, and preprocessing has already been performed on the beta values.
Given the parameters of a distribution, the package uses the concept of alpha-outliers by Davies and Gather (1993) to flag outliers in a data set. See Davies, L.; Gather, U. (1993): The identification of multiple outliers, JASA, 88 423, 782-792, <doi:10.1080/01621459.1993.10476339> for details.
Enables creation of visualizations using the CanvasXpress framework in R. CanvasXpress is a standalone JavaScript library for reproducible research with complete tracking of data and end-user modifications stored in a single PNG image that can be played back. See <https://www.canvasxpress.org> for more information.
Manually plot fully customisable path diagrams for structural equation models (SEM). Map out node positions using simple coordinates and specify where on the perimeter of each node paths begin and end. Extensive fine-tuning options allow the creation of a path diagram exactly as envisioned, entirely within R.
This package provides functions for obtaining estimates of the parameter of the niche preemption model (also known as the geometric series), in particular a maximum likelihood estimator (Graffelman, 2021) <doi:10.1101/2021.01.27.428381>. The niche preemption model is a widely used model in ecology and biodiversity studies.
Utilize the CDF penalty function to estimate a penalized linear model. It enables you to display some graphical representations and determine whether the Karush-Kuhn-Tucker conditions are met. For more details about the theory, please refer to Cuntrera, D., Augugliaro, L., & Muggeo, V. M. (2022) <arXiv:2212.08582>.
Enhances dynamic effect plots as suggested in Freyaldenhoven and Hansen (2026) <https://simonfreyaldenhoven.github.io/papers/Plausible_bounds.pdf>. Data-driven smoothing delivers a smooth estimated path with potentially improved point estimation properties and confidence regions covering a surrogate that can be substantially tighter than conventional pointwise or uniform bands.
Provide various functions and tools to help fit models for estimating treatment effects in stepped wedge cluster randomized trials. Implements methods described in Kenny, Voldal, Xia, and Heagerty (2022) "Analysis of stepped wedge cluster randomized trials in the presence of a time-varying treatment effect", <doi:10.1002/sim.9511>.
Troubleshooting reactive data in shiny can be difficult. These functions will convert reactive data frames into functions and load all assigned objects into your local environment. If you create a dummy input object, as the function will suggest, you will be able to test your server and ui functions interactively.
This package provides a convenient interface for formatting SQL queries directly within R'. It acts as a wrapper around the sql_format Rust crate. The package allows you to format SQL code with customizable options, including indentation, case formatting, and more, ensuring your SQL queries are clean, readable, and consistent.
TidyTuesday is a project by the Data Science Learning Community in which they post a weekly dataset in a public data repository (<https://github.com/rfordatascience/tidytuesday>) for people to analyze and visualize. This package provides the tools to easily download this data and the description of the source.
Computes correlation matrices as tidy data frames and creates publication-ready correlograms with ggplot2'. The package is designed for teaching and exploratory analysis workflows where users want one consistent interface for selecting numeric variables, calculating pairwise correlations, optionally estimating p-values, reordering variables, and drawing tile, point, or mixed correlograms.
This package is developed for facilitating parallel computing in R. It is capable to create an R object in the shared memory space and share the data across multiple R processes. It avoids the overhead of memory dulplication and data transfer, which make sharing big data object across many clusters possible.
Using spatial or bulk gene expression data, estimates abundance of mixed cell types within each observation. Based on "Advances in mixed cell deconvolution enable quantification of cell types in spatial transcriptomic data", Danaher (2022). Designed for use with the NanoString GeoMx platform, but applicable to any gene expression data.
Fast generators and iterators for permutations, combinations, integer partitions and compositions. The arrangements are in lexicographical order and generated iteratively in a memory efficient manner. It has been demonstrated that arrangements outperforms most existing packages of similar kind. Benchmarks could be found at <https://randy3k.github.io/arrangements/articles/benchmark.html>.
Pull raw and pre-cleaned versions of national and state-level COVID-19 time-series data from covid19india.org <https://www.covid19india.org>. Easily obtain and merge case count data, testing data, and vaccine data. Also assists in calculating the time-varying effective reproduction number with sensible parameters for COVID-19.
Estimation of average treatment effects (ATE) of point interventions on time-to-event outcomes with K competing risks (K can be 1). The method uses propensity scores and inverse probability weighting for emulation of baseline randomization, which is described in Charpignon et al. (2022) <doi:10.1038/s41467-022-35157-w>.
The dentomedical package provides a comprehensive suite of tools for medical and dental research. It includes automated descriptive statistics, bivariate analysis with intelligent test selection, logistic regression, and diagnostic accuracy assessment. All functions generate publication-ready tables using flextable', ensuring reproducibility and clarity suitable for manuscripts, reports, and clinical research workflows.
This package provides methods for estimating causal effects in the presence of interference described in B. Saul and M. Hugdens (2017) <doi:10.18637/jss.v082.i02>. Currently it implements the inverse-probability weighted (IPW) estimators proposed by E.J. Tchetgen Tchetgen and T.J. Vanderweele (2012) <doi:10.1177/0962280210386779>.
Exports two functions implementing multi-way clustering using the method suggested by Cameron, Gelbach, & Miller (2011) and cluster (or block) bootstrapping for estimating variance-covariance matrices. Normal one and two-way clustering matches the results of other common statistical packages. Missing values are handled transparently and rudimentary parallelization support is provided.
Package to carry out merged block randomization (Van der Pas (2019), <doi:10.1177/1740774519827957>), a restricted randomization method designed for small clinical trials (at most 100 subjects) or trials with small strata, for example in multicentre trials. It can be used for more than two groups or unequal randomization ratios.
Combines Autoencoders with the STATIS (Structuring Three-way Arrays in Statistics) methodology for dimensional reduction and visualization of multi-way data (tables x individuals x variables). Methods are based on L'Hermier des Plantes (1976) and Carrera Buri & Galindo-Villardón (2026) <https://www.mdpi.com/1999-4893/19/8/637/pdf>.