Downloads and parses the risk-free interest rate ('RFR') term structures published monthly by the European Insurance and Occupational Pensions Authority ('EIOPA') for Solvency II calculations. Provides a tidy data frame interface to the data, accessed via the official EIOPA feed at <https://www.eiopa.europa.eu/feed/53/rss_en>.

The ESTIMATE package infers tumor purity from expression data as a function of immune and stromal infiltrate, but requires writing of intermediate files, is un-pipeable, and performs poorly when presented with modern datasets with current gene symbols. tidyestimate a fast, tidy, modern reimagination of ESTIMATE (2013) <doi:10.1038/ncomms3612>.

This package provides scalogram based wavelet tools for time series analysis: wavelet power spectrum, scalogram, windowed scalogram, windowed scalogram difference (see Bolos et al. (2017) <doi:10.1016/j.amc.2017.05.046>), scale index and windowed scale index (Benitez et al. (2010) <doi:10.1016/j.camwa.2010.05.010>).

This package provides an interface to vinecopulib', a C++ library for vine copula modeling. The rvinecopulib package implements the core features of the popular VineCopula package, in particular inference algorithms for both vine copula and bivariate copula models. Advantages over VineCopula are a sleeker and more modern API, improved performances, especially in high dimensions, nonparametric and multi-parameter families, and the ability to model discrete variables. The rvinecopulib package includes vinecopulib as header-only C++ library (currently version 1.0.0). Thus users do not need to install vinecopulib itself in order to use rvinecopulib'. Since their initial releases, vinecopulib is licensed under the MIT License, and rvinecopulib is licensed under the GNU GPL version 3.

Emacs Org Roam is a solution for taking non-hierarchical notes with Org mode. Notes are captured without hierarchy and are connected by tags. Notes can be found and created quickly. Org Roam should also work as a plug-and-play solution for anyone already using Org mode for their personal wiki.

The pip-run command provides on-demand temporary package installation for a single interpreter run. It replaces this series of commands:

$ virtualenv --python pythonX.X --system-site-packages /tmp/env
$ /tmp/env/bin/pip install pkg1 pkg2 -r reqs.txt
$ /tmp/env/bin/python ...
$ rm -rf /tmp/env

CalibraCurve is a computational tool designed to generate calibration curves for targeted mass spectrometry-based quantitative data. It is applicable to various omics disciplines, including proteomics, lipidomics, and metabolomics. The package also offers functionalities for data and calibration curve visualization and concentration prediction from new datasets based on the established curves.

MetaboSignal is an R package that allows merging, analyzing and customizing metabolic and signaling KEGG pathways. It is a network-based approach designed to explore the topological relationship between genes (signaling- or enzymatic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape and regulatory networks of metabolic phenotypes.

NormalyzerDE provides screening of normalization methods for LC-MS based expression data. It calculates a range of normalized matrices using both existing approaches and a novel time-segmented approach, calculates performance measures and generates an evaluation report. Furthermore, it provides an easy utility for Limma- or ANOVA- based differential expression analysis.

The package contains local copy of the Synaptic proteome database. On top of this it provide a set of utility R functions to query and analyse its content. It allows extraction of information for specific genes and building the protein-protein interaction graph for gene sets, synaptic compartments, and brain regions.

This package provides functions for differential chromatin interaction analysis between two single-cell Hi-C data groups. It includes tools for imputation, normalization, and differential analysis of chromatin interactions. The package implements pooling techniques for imputation and offers methods to normalize and test for differential interactions across single-cell Hi-C datasets.

This package provides tools to create binary dosage files from either VCF or GEN files, merge binary dosage files, and read binary dosage files. Binary dosage files tend to have quicker read times than VCF and GEN formats. There is a small increase in size compared to compressed VCF and GEN files.

Extends blockr.core with interactive blocks for visual data wrangling using dplyr and tidyr operations. Users can build data transformation pipelines through a graphical interface without writing code directly. Includes blocks for filtering, selecting, mutating, summarizing, joining, and arranging data, with support for complex expressions, grouping operations, and real-time validation.

Simple interpolation methods designed to be used from C code. Supports constant, linear and spline interpolation. An R wrapper is included but this package is primarily designed to be used from C code using LinkingTo'. The spline calculations are classical cubic interpolation, e.g., Forsythe, Malcolm and Moler (1977) <ISBN: 9780131653320>.

This package provides a wrapper for circlize'. All components are based on classes and objects. Users can use the addition symbol (+) to combine components for a circular visualization with ggplot2 style.The package is described in Zhang Z, Cao T, Huang Y and Xia Y (2025) <doi:10.3389/fgene.2025.1535368>.

There are many estimators of false discovery rate. In this package we compute the Nonlocal False Discovery Rate (NFDR) and the estimators of local false discovery rate: Corrected False discovery Rate (CFDR), Re-ranked False Discovery rate (RFDR) and the blended estimator. Bickel, D.R., Rahal, A. (2019) <https://tinyurl.com/kkdc9rk8>.

Various estimators of causal effects based on inverse probability weighting, doubly robust estimation, and double machine learning. Specifically, the package includes methods for estimating average treatment effects, direct and indirect effects in causal mediation analysis, and dynamic treatment effects based on different identification strategies (unconfoundedness, instruments, difference-in-differences, regression discontinuity designs).

The EconDataverse is a universe of open-source packages to work seamlessly with economic data. This package is designed to make it easy to download selected datasets that are preprocessed by EconDataverse packages and publicly hosted on Hugging Face'. Learn more about the EconDataverse at <https://www.econdataverse.org>.

Imports, validates, quality-checks, preprocesses, summarises, synchronises, models, plots, and reports Gazepoint Biometrics exports. The package focuses on Gazepoint-specific biometric channels such as GSR/EDA, heart rate, interbeat intervals, pulse signals, engagement dial, TTL markers, and synchronisation fields that can be combined with Gazepoint GP3 and GP3 HD eye-tracking workflows.

Automated cell type annotation for single-cell RNA sequencing data using consensus predictions from multiple large language models. Integrates with Seurat objects and provides uncertainty quantification for annotations. Supports various LLM providers including OpenAI, Anthropic, and Google. For details see Yang et al. (2026) <doi:10.1038/s42003-026-10420-8>.

Free United Kingdom National Health Service (NHS) and other healthcare, or population health-related data for education and training purposes. This package contains synthetic data based on real healthcare datasets, or cuts of open-licenced official data. This package exists to support skills development in the NHS-R community: <https://nhsrcommunity.com/>.

This package provides a model-agnostic framework for selecting dataset-specific imputation methods for missing values in numerical data related to pain. Lotsch J, Ultsch A (2025) "A model-agnostic framework for dataset-specific selection of missing value imputation methods in pain-related numerical data" Canadian Journal of Pain (in minor revision).

This package implements a suite of tools for outlier detection and treatment in data mining. It includes univariate methods (Z-score, Interquartile Range), multivariate detection using Mahalanobis distance, and density-based detection (Local Outlier Factor) via the dbscan package. It also provides functions for visualization using ggplot2 and data cleaning via Winsorization.

This package provides bindings to a C grammar for Tree-sitter, to be used alongside the treesitter package. Tree-sitter builds concrete syntax trees for source files and can efficiently update them or generate code like producing R C API wrappers from C functions, structs and global definitions from header files.