Code to identify functional enrichments across diverse taxa in phylogenetic tree, particularly where these taxa differ in abundance across samples in a non-random pattern. The motivation for this approach is to identify microbial functions encoded by diverse taxa that are at higher abundance in certain samples compared to others, which could indicate that such functions are broadly adaptive under certain conditions. See GitHub repository for tutorial and examples: <https://github.com/gavinmdouglas/POMS/wiki>. Citation: Gavin M. Douglas, Molly G. Hayes, Morgan G. I. Langille, Elhanan Borenstein (2022) <doi:10.1093/bioinformatics/btac655>.

This package provides a package for selecting the most relevant features (genes) in the high-dimensional binary classification problems. The discriminative features are identified using analyzing the overlap between the expression values across both classes. The package includes functions for measuring the proportional overlapping score for each gene avoiding the outliers effect. The used measure for the overlap is the one defined in the "Proportional Overlapping Score (POS)" technique for feature selection. A gene mask which represents a gene's classification power can also be produced for each gene (feature). The set size of the selected genes might be set by the user. The minimum set of genes that correctly classify the maximum number of the given tissue samples (observations) can be also produced.

This package provides tools to sort, edit and prune pedigrees and to extract the inbreeding coefficients and the relationship matrix (includes code for pedigrees from self-pollinated species). The use of pedigree data is central to genetics research within the animal and plant breeding communities to predict breeding values. The relationship matrix between the individuals can be derived from pedigree structure ('Vazquez et al., 2010') <doi:10.2527/jas.2009-1952>.

The use of overparameterization is proposed with combinatorial analysis to test a broader spectrum of possible ARIMA models. In the selection of ARIMA models, the most traditional methods such as correlograms or others, do not usually cover many alternatives to define the number of coefficients to be estimated in the model, which represents an estimation method that is not the best. The popstudy package contains several tools for statistical analysis in demography and time series based in Shryock research (Shryock et. al. (1980) <https://books.google.co.cr/books?id=8Oo6AQAAMAAJ>).

This package provides a set of tools to implement the non-parametric bounds and Bayesian methods for assessing post-treatment bias developed in Blackwell, Brown, Hill, Imai, and Yamamoto (2025) <doi:10.1017/pan.2025.3>.

Provide easy methods to translate pieces of text. Functions send requests to translation services online.

This package provides permutation methods for testing in high-dimensional linear models. The tests are often robust against heteroscedasticity and non-normality and usually perform well under anti-sparsity. See Hemerik, Thoresen and Finos (2021) <doi:10.1080/00949655.2020.1836183>.

This package creates and manages a provenance graph corresponding to the provenance created by the rdtLite package, which collects provenance from R scripts. rdtLite is available on CRAN. The provenance format is an extension of the W3C PROV JSON format (<https://www.w3.org/Submission/2013/SUBM-prov-json-20130424/>). The extended JSON provenance format is described in <https://github.com/End-to-end-provenance/ExtendedProvJson>.

Be responsible when scraping data from websites by following polite principles: introduce yourself, ask for permission, take slowly and never ask twice.

Conduct permutation One-Way or Two-Way Analysis of Variance in R. Use different permutation types for two-way designs.

Generate nicely formatted HTML tables to display estimation results for pharmacometric models.

Estimation and inference of spatial and spatio-temporal semiparametric models including spatial or spatio-temporal non-parametric trends, parametric and non-parametric covariates and, possibly, a spatial lag for the dependent variable and temporal correlation in the noise. The spatio-temporal trend can be decomposed in ANOVA way including main and interaction functional terms. Use of SAP algorithm to estimate the spatial or spatio-temporal trend and non-parametric covariates. The methodology of these models can be found in next references Basile, R. et al. (2014), <doi:10.1016/j.jedc.2014.06.011>; Rodriguez-Alvarez, M.X. et al. (2015) <doi:10.1007/s11222-014-9464-2> and, particularly referred to the focus of the package, Minguez, R., Basile, R. and Durban, M. (2020) <doi:10.1007/s10260-019-00492-8>.

Spearman's rank correlation test with precomputed exact null distribution for n <= 22.

Implementation of the Phoenix and Phoenix-8 Sepsis Criteria as described in "Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock" by Sanchez-Pinto, Bennett, DeWitt, Russell et al. (2024) <doi:10.1001/jama.2024.0196> (Drs. Sanchez-Pinto and Bennett contributed equally to this manuscript; Dr. DeWitt and Mr. Russell contributed equally to the manuscript), "International Consensus Criteria for Pediatric Sepsis and Septic Shock" by Schlapbach, Watson, Sorce, Argent, et al. (2024) <doi:10.1001/jama.2024.0179> (Drs Schlapbach, Watson, Sorce, and Argent contributed equally) and the application note "phoenix: an R package and Python module for calculating the Phoenix pediatric sepsis score and criteria" by DeWitt, Russell, Rebull, Sanchez-Pinto, and Bennett (2024) <doi:10.1093/jamiaopen/ooae066>.

Two-sample power-enhanced mean tests, covariance tests, and simultaneous tests on mean vectors and covariance matrices for high-dimensional data. Methods of these PE tests are presented in Yu, Li, and Xue (2022) <doi:10.1080/01621459.2022.2126781>; Yu, Li, Xue, and Li (2022) <doi:10.1080/01621459.2022.2061354>.

This package provides several measures ((dis)similarity, distance/metric, correlation, entropy) for comparing two partitions of the same set of objects. The different measures can be assigned to three different classes: Pair comparison (containing the famous Jaccard and Rand indices), set based, and information theory based. Many of the implemented measures can be found in Albatineh AN, Niewiadomska-Bugaj M and Mihalko D (2006) <doi:10.1007/s00357-006-0017-z> and Meila M (2007) <doi:10.1016/j.jmva.2006.11.013>. Partitions are represented by vectors of class labels which allow a straightforward integration with existing clustering algorithms (e.g. kmeans()). The package is mostly based on the S4 object system.

Evaluation of the pdf and the cdf of the univariate, noncentral, p-generalized normal distribution. Sampling from the univariate, noncentral, p-generalized normal distribution using either the p-generalized polar method, the p-generalized rejecting polar method, the Monty Python method, the Ziggurat method or the method of Nardon and Pianca. The package also includes routines for the simulation of the bivariate, p-generalized uniform distribution and the simulation of the corresponding angular distribution.

The function pointdensity returns a density count and the temporal average for every point in the original list. The dataframe returned includes four columns: lat, lon, count, and date_avg. The "lat" column is the original latitude data; the "lon" column is the original longitude data; the "count" is the density count of the number of points within a radius of radius*grid_size (the neighborhood); and the date_avg column includes the average date of each point in the neighborhood.

Deterministic Pena-Yohai initial estimator for robust S estimators of regression. The procedure is described in detail in Pena, D., & Yohai, V. (1999) <doi:10.2307/2670164>.

Interactively annotate base R graphics plots with freehand drawing, symbols (points, lines, arrows, rectangles, circles, ellipses), and text. This is useful for teaching, for example to visually explain certain plot elements, and creating quick sketches.

Automate formation and evaluation of polynomial regression models. The motivation for this package is described in Polynomial Regression As an Alternative to Neural Nets by Xi Cheng, Bohdan Khomtchouk, Norman Matloff, and Pete Mohanty (<arXiv:1806.06850>).

Multivariate ordered probit model, i.e. the extension of the scalar ordered probit model where the observed variables have dimension greater than one. Estimation of the parameters is done via maximization of the pairwise likelihood, a special case of the composite likelihood obtained as product of bivariate marginal distributions. The package uses the Fortran 77 subroutine SADMVN by Alan Genz, with minor adaptations made by Adelchi Azzalini in his "mvnormt" package for evaluating the two-dimensional Gaussian integrals involved in the pairwise log-likelihood. Optimization of the latter objective function is performed via quasi-Newton box-constrained optimization algorithm, as implemented in nlminb.

Colour palettes for data, based on some well known public data sets. Includes helper functions to map absolute values to known palettes, and capture the work of image colour mapping as raster data sets.

The 2017 American College of Cardiology and American Heart Association blood pressure guideline recommends using 10-year predicted atherosclerotic cardiovascular disease risk to guide the decision to initiate or intensify antihypertensive medication. The guideline recommends using the Pooled Cohort risk prediction equations to predict 10-year atherosclerotic cardiovascular disease risk. This package implements the original Pooled Cohort risk prediction equations and also incorporates updated versions based on more contemporary data and statistical methods.