This package provides a statistical method to impute the missing values in accelerometer data. The methodology includes both parametric and semi-parametric multiple imputations under the zero-inflated Poisson lognormal model. It also provides multiple functions to preprocess the accelerometer data previous to the missing data imputation. These include detecting the wearing and the non-wearing time, selecting valid days and subjects, and creating plots.

Rocq is an interactive theorem prover, or proof assistant. It provides a formal language to write mathematical definitions, executable algorithms and theorems together with an environment for semi-interactive development of machine-checked proofs.

This package provides the coqidetop language server, an implementation of Rocq's XML protocol which allows clients, such as RocqIDE, to interact with the Rocq Prover in a structured way.

This package contains diverse functionality to extend the usage of the iSEE package, including additional classes for the panels or modes facilitating the analysis of pathway analysis results. This package does not perform pathway analysis. Instead, it provides methods to embed precomputed pathway analysis results in a SummarizedExperiment object, in a manner that is compatible with interactive visualisation in iSEE applications.

The tuberculosis R/Bioconductor package features tuberculosis gene expression data for machine learning. All human samples from GEO that did not come from cell lines, were not taken postmortem, and did not feature recombination have been included. The package has more than 10,000 samples from both microarray and sequencing studies that have been processed from raw data through a hyper-standardized, reproducible pipeline.

Generates the equiplot, an iconic dot-plot graph for visualizing inequalities, as well as three complex inequality measures: the slope index of inequality, the concentration index and the mean absolute difference to the mean. For more details see World Health Organization (2013) <https://www.who.int/docs/default-source/gho-documents/health-equity/handbook-on-health-inequality-monitoring/handbook-on-health-inequality-monitoring.pdf>.

Aids in learning statistical functions incorporating the result of calculus done with each function and how they are obtained, that is, which equation and variables are used. Also for all these equations and their related variables detailed explanations and interactive exercises are also included. All these characteristics allow to the package user to improve the learning of statistics basics by means of their use.

This package provides functions for fitting and validation of models for subgroup identification and personalized medicine / precision medicine under the general subgroup identification framework of Chen et al. (2017) <doi:10.1111/biom.12676>. This package is intended for use for both randomized controlled trials and observational studies and is described in detail in Huling and Yu (2021) <doi:10.18637/jss.v098.i05>.

This package provides three basic functions that support an implementation of Case 2 (profile case) best-worst scaling. The first is to convert an orthogonal main-effect design into questions, the second is to create a dataset suitable for analysis, and the third is to calculate count-based scores. For details, see Aizaki and Fogarty (2019) <doi:10.1016/j.jocm.2019.100171>.

Stores objects (e.g. neural networks) that are needed for using Sojourn accelerometer methods. For more information, see Lyden K, Keadle S, Staudenmayer J, & Freedson P (2014) <doi:10.1249/MSS.0b013e3182a42a2d>, Ellingson LD, Schwabacher IJ, Kim Y, Welk GJ, & Cook DB (2016) <doi:10.1249/MSS.0000000000000915>, and Hibbing PR, Ellingson LD, Dixon PM, & Welk GJ (2018) <doi:10.1249/MSS.0000000000001486>.

This is an implementation of the Future API on top of the callr package. This allows you to process futures, as defined by the future package, in parallel out of the box, on your local machine. Contrary to backends relying on the parallel package (e.g. future::multisession) and socket connections, the callr backend provided here can run more than 125 parallel R processes.

ChIPanalyser is a package to predict and understand TF binding by utilizing a statistical thermodynamic model. The model incorporates 4 main factors thought to drive TF binding: Chromatin State, Binding energy, Number of bound molecules and a scaling factor modulating TF binding affinity. Taken together, ChIPanalyser produces ChIP-like profiles that closely mimic the patterns seens in real ChIP-seq data.

An interactive web application for quality control, filtering and trimming of FASTQ files. This user-friendly tool combines a pipeline for data processing based on Biostrings and ShortRead infrastructure, with a cutting-edge visual environment. Single-Read and Paired-End files can be locally processed. Diagnostic interactive plots (CG content, per-base sequence quality, etc.) are provided for both the input and output files.

NetPathMiner is a general framework for network path mining using genome-scale networks. It constructs networks from KGML, SBML and BioPAX files, providing three network representations, metabolic, reaction and gene representations. NetPathMiner finds active paths and applies machine learning methods to summarize found paths for easy interpretation. It also provides static and interactive visualizations of networks and paths to aid manual investigation.

This package provides functions for processing and analyzing survey data from the All of Us Social Determinants of Health (AOUSDOH) program, including tools for calculating health and well-being scores, recoding variables, and simplifying survey data analysis. For more details see - Koleck TA, Dreisbach C, Zhang C, Grayson S, Lor M, Deng Z, Conway A, Higgins PDR, Bakken S (2024) <doi:10.1093/jamia/ocae214>.

Efficient Markov Chain Monte Carlo (MCMC) algorithms for the fully Bayesian estimation of vectorautoregressions (VARs) featuring stochastic volatility (SV). Implements state-of-the-art shrinkage priors following Gruber & Kastner (2025) <doi:10.1016/j.ijforecast.2025.02.001>. Efficient equation-per-equation estimation following Kastner & Huber (2020) <doi:10.1002/for.2680> and Carrerio et al. (2021) <doi:10.1016/j.jeconom.2021.11.010>.

This package implements two out-of box classifiers presented in <doi:10.1002/env.2848> for distinguishing forest and non-forest terrain images. Under these algorithms, there are frequentist approaches: one parametric, using stable distributions, and another one- non-parametric, using the squared Mahalanobis distance. The package also contains functions for data handling and building of new classifiers as well as some test data set.

This package provides tools for quantifying Traditional Ecological Knowledge (TEK), modeling TEK in decision frameworks, and designing structured decision-framing exercises in conservation and development contexts. The package implements quantitative ethnobotany indices (Use Value, Relative Frequency of Citation, etc.) but positions them within a larger framework of Bayesian modeling and participatory decision analysis. Includes critical assessment of indices limitations and case studies of participatory workshops.

Calculates calorific values (gross and net), density, relative density, and Wobbe indices together with their standard uncertainties from natural gas composition, implementing the method of ISO 6976:2016 "Natural Gas â Calculation of calorific values, density, relative density and Wobbe indices from composition". Uncertainty propagation follows Annex B of that standard. Reference: International Organization for Standardization (2016) <https://www.iso.org/standard/55842.html>.

Analyze graph/network data using L1 centrality and prestige. Functions for deriving global, local, and group L1 centrality/prestige are provided. Routines for visual inspection of a graph/network are also provided. Details are in Kang and Oh (2026a) <doi:10.1080/01621459.2025.2520467>, Kang and Oh (2026b) <doi:10.1080/00031305.2025.2563730>, and Kang (2025) <doi:10.23170/snu.000000188358.11032.0001856>.

Estimates key quantities in causal mediation analysis - including average causal mediation effects (indirect effects), average direct effects, total effects, and proportions mediated - in the presence of multiple uncausally related mediators. Methods are described by Jerolon et al., (2021) <doi:10.1515/ijb-2019-0088> and extended to accommodate survival outcomes as described by Domingo-Relloso et al., (2024) <doi:10.1101/2024.02.16.24302923>.

This package provides shared worker-plan helpers, covariance utilities, model reexports, equation rendering methods, and package data used by the split nlmixr2 extension packages, including nlmixr2boot', nlmixr2llp', nlmixr2scm', and nlmixr2sir'. These helpers give the extension packages a common canonical raw-results schema, run-cache and seeding infrastructure, and equation-printing methods so that each extension package does not need to reimplement this shared functionality separately.

This package provides functions for generating novel partially residual balanced multi-session designs. These designs arrange products over sessions and periods under partial balance restrictions and compute canonical efficiency factors for direct and residual (carryover) effects. For general background on PRBMS and related crossover design literature, see Aggarwal and Jha (2006) <doi:10.1080/03610920600695824> and Fardos et al. (2023) <doi:10.18576/jsap/120227>.

This package provides a tidy framework for working with archaeological stratigraphy and chronology. Includes tools for reading, analysing, and visualising stratigraphic sequences (Harris matrices) as directed graphs following the definition of Dye and Buck (2015) <doi:10.1016/j.jas.2015.08.008> and an R interface to the Chronological Query Language (CQL) used in OxCal by Bronk Ramsey (2009) <doi:10.1017/S0033822200033865>.

This package provides a simple user-friendly library based on the python module reservoirpy'. It provides a flexible interface to implement efficient Reservoir Computing (RC) architectures with a particular focus on Echo State Networks (ESN). Some of its features are: offline and online training, parallel implementation, sparse matrix computation, fast spectral initialization, advanced learning rules (e.g. Intrinsic Plasticity) etc. It also makes possible to easily create complex architectures with multiple reservoirs (e.g. deep reservoirs), readouts, and complex feedback loops. Moreover, graphical tools are included to easily explore hyperparameters. Finally, it includes several tutorials exploring time series forecasting, classification and hyperparameter tuning. For more information about reservoirpy', please see Trouvain et al. (2020) <doi:10.1007/978-3-030-61616-8_40>. This package was developed in the framework of the University of Bordeauxâ s IdEx "Investments for the Future" program / RRI PHDS.