Design parameters of the optimal two-period multiarm platform design (controlling for either family-wise error rate or pair-wise error rate) can be calculated using this package, allowing pre-planned deferred arms to be added during the trial. More details about the design method can be found in the paper: Pan, H., Yuan, X. and Ye, J. (2022) "An optimal two-period multiarm platform design with new experimental arms added during the trial". Manuscript submitted for publication. For additional references: Dunnett, C. W. (1955) <doi:10.2307/2281208>.
The AFfunction() is a function which returns an estimate of the Attributable Fraction (AF) and a plot of the AF as a function of heritability, disease prevalence, size of target group and intervention effect. Since the AF is a function of several factors, a shiny app is used to better illustrate how the relationship between the AF and heritability depends on several other factors. The app is ran by the function runShinyApp(). For more information see Dahlqwist E et al. (2019) <doi:10.1007/s00439-019-02006-8>.
LaBB-CAT is a web-based language corpus management system developed by the New Zealand Institute of Language, Brain and Behaviour (NZILBB) - see <https://labbcat.canterbury.ac.nz>. This package defines functions for accessing corpus data in a LaBB-CAT instance. You must have at least version 20230818.1400 of LaBB-CAT to use this package. For more information about LaBB-CAT', see Robert Fromont and Jennifer Hay (2008) <doi:10.3366/E1749503208000142> or Robert Fromont (2017) <doi:10.1016/j.csl.2017.01.004>.
TaskJuggler (tj3) is a project management tool for project planning and tracking using a domain specific language; projects are plain text files written using your favourite text editor. It includes reporting in HTML, CSV or iCalendar format and an email based status tracking system to send and receive time sheets from collaborators.
It covers the complete spectrum of project management tasks from the first idea to the completion of the project. It assists you during project scoping, resource assignment, cost and revenue planning, risk and communication management, status tracking and reporting.
Estimate and understand individual-level variation in transmission. Implements density and cumulative compound Poisson discrete distribution functions (Kremer et al. (2021) <doi:10.1038/s41598-021-93578-x>), as well as functions to calculate infectious disease outbreak statistics given epidemiological parameters on individual-level transmission; including the probability of an outbreak becoming an epidemic/extinct (Kucharski et al. (2020) <doi:10.1016/S1473-3099(20)30144-4>), or the cluster size statistics, e.g. what proportion of cases cause X\% of transmission (Lloyd-Smith et al. (2005) <doi:10.1038/nature04153>).
It makes the creation of networks from sequences of RNA, with this is done the abstraction of characteristics of these networks with a methodology of maximum entropy for the purpose of making a classification between the classes of the sequences. There are two data present in the BASiNET package, "mRNA", and "ncRNA" with 10 sequences. These sequences were taken from the data set used in the article (LI, Aimin; ZHANG, Junying; ZHOU, Zhongyin, 2014) <doi:10.1186/1471-2105-15-311>, these sequences are used to run examples.
This package provides tools for sensitivity analysis of LSD simulation models. Reads object-oriented data produced by LSD simulation models and performs screening and global sensitivity analysis (Sobol decomposition method, Saltelli et al. (2008) ISBN:9780470725177). A Kriging or polynomial meta-model (Kleijnen (2009) <doi:10.1016/j.ejor.2007.10.013>) is estimated using the simulation data to provide the data required by the Sobol decomposition. LSD (Laboratory for Simulation Development) is free software developed by Marco Valente and Marcelo C. Pereira (documentation and downloads available at <https://www.labsimdev.org/>).
This package provides functions to aid in the design and analysis of agronomic and agricultural experiments through easy access to documentation and helper functions, especially for users who are learning these concepts. While not required for most functionality, this package enhances the `asreml` package which provides a computationally efficient algorithm for fitting mixed models using Residual Maximum Likelihood. It is a commercial package that can be purchased as asreml-R from VSNi <https://vsni.co.uk/>, who will supply a zip file for local installation/updating (see <https://asreml.kb.vsni.co.uk/>).
This package provides functions for converting time series of spatial abundance or density data in raster format to vector fields of population movement using the digital image correlation technique. More specifically, the functions in the package compute cross-covariance using discrete fast Fourier transforms for computational efficiency. Vectors in vector fields point in the direction of highest two dimensional cross-covariance. The package has a novel implementation of the digital image correlation algorithm that is designed to detect persistent directional movement when image time series extend beyond a sequence of two raster images.
This package implements IV-estimator and Bayesian estimator for linear-in-means Spatial Autoregressive (SAR) model (see LeSage, 1997 <doi:10.1177/016001769702000107>; Lee, 2004 <doi:10.1111/j.1468-0262.2004.00558.x>; Bramoullé et al., 2009 <doi:10.1016/j.jeconom.2008.12.021>), while assuming that only a partial information about the network structure is available. Examples are when the adjacency matrix is not fully observed or when only consistent estimation of the network formation model is available (see Boucher and Houndetoungan <doi:10.48550/arXiv.2509.08145>).
Create a custom sized Core Collection based on a distance matrix and applying the A-NE (accession nearest entry), E-NE (entry nearest entry) or E-E (entry entry) method as introduced in Jansen and van Hintum (2007) <doi:10.1007/s00122-006-0433-9> and further elaborated on in Odong, T.L. (2012) <https://edepot.wur.nl/212422>. Optionally a list of preselected accessions to be included into the core can be set. For each accession in the computed core, if available nearby accessions are retrievable that can be used as an alternative.
Provide the safe color set for color blindness, the simulator of protanopia, deuteranopia. The color sets are collected from: Wong, B. (2011) <doi:10.1038/nmeth.1618>, and <http://mkweb.bcgsc.ca/biovis2012/>. The simulations of the appearance of the colors to color-deficient viewers were based on algorithms in Vienot, F., Brettel, H. and Mollon, J.D. (1999) <doi:10.1002/(SICI)1520-6378(199908)24:4%3C243::AID-COL5%3E3.0.CO;2-3>. The cvdPlot() function to generate ggplot grobs of simulations were modified from <https://github.com/clauswilke/colorblindr>.
This package performs analysis of popular experimental designs used in the field of biological research. The designs covered are completely randomized design, randomized complete block design, factorial completely randomized design, factorial randomized complete block design, split plot design, strip plot design and latin square design. The analysis include analysis of variance, coefficient of determination, normality test of residuals, standard error of mean, standard error of difference and multiple comparison test of means. The package has functions for transformation of data and yield data conversion. Some datasets are also added in order to facilitate examples.
Aids in the analysis of genes influencing cancer survival by including a principal function, calculator(), which calculates the P-value for each provided gene under the optimal cutoff in cancer survival studies. Grounded in methodologies from significant works, this package references Therneau's survival package (Therneau, 2024; <https://CRAN.R-project.org/package=survival>) and the survival analysis extensions by Therneau and Grambsch (2000, ISBN 0-387-98784-3). It also integrates the survminer package by Kassambara et al. (2021; <https://CRAN.R-project.org/package=survminer>), enhancing survival curve visualizations with ggplot2'.
Kappa statistics is one of the most used methods to evaluate the effectiveness of inpsections based on attribute assessments in industry. However, its estimation by available methods does not provide its "real" or "intrinstic" value. This package provides functions for the computation of the intrinsic kappa value as it is described in: Rafael Sanchez-Marquez, Frank Gerhorst and David Schindler (2023) "Effectiveness of quality inspections of attributive characteristics â A novel and practical method for estimating the â intrinsicâ value of kappa based on alpha and beta statistics." <doi:10.1016/j.cie.2023.109006>.
Introduces the symbolicQspray objects. Such an object represents a multivariate polynomial whose coefficients are fractions of multivariate polynomials with rational coefficients. The package allows arithmetic on such polynomials. It is based on the qspray and ratioOfQsprays packages. Some functions for qspray polynomials have their counterpart for symbolicQspray polynomials. A symbolicQspray polynomial should not be seen as a polynomial on the field of fractions of rational polynomials, but should rather be seen as a polynomial with rational coefficients depending on some parameters, symbolically represented, with a dependence given by fractions of rational polynomials.
Univariate stratification of survey populations with a generalization of the Lavallee-Hidiroglou method of stratum construction. The generalized method takes into account a discrepancy between the stratification variable and the survey variable. The determination of the optimal boundaries also incorporate, if desired, an anticipated non-response, a take-all stratum for large units, a take-none stratum for small units, and a certainty stratum to ensure that some specific units are in the sample. The well known cumulative root frequency rule of Dalenius and Hodges and the geometric rule of Gunning and Horgan are also implemented.
In semi-structured interviews that use the framework method, it is not always clear how refinements to interview questions affect the decision of when to stop interviews. The trend of novel and duplicate interview codes (novel codes are information that other interviewees have not previously mentioned) provides insight into the richness of qualitative information. This package provides tools to visualise when refinements occur and how that affects the trends of novel and duplicate codes. These visualisations, when used progressively as new interviews are finished, can help the researcher to decide on a stopping point for their interviews.
This package provides a tool set for food information and dietary assessment. It uses food composition data from several reference databases, including: USDA (United States), CIQUAL (France), BEDCA (Spain), CNF (Canada) and STFCJ (Japan). NutrienTrackeR calculates the intake levels for both macronutrient and micronutrients, and compares them with the recommended dietary allowances (RDA). It includes a number of visualization tools, such as time series plots of nutrient intake, and pie-charts showing the main foods contributing to the intake level of a given nutrient. A shiny app exposing the main functionalities of the package is also provided.
Seed vigor is defined as the sum total of those properties of the seed which determine the level of activity and performance of the seed or seed lot during germination and seedling emergence. Testing for vigor becomes more important for carryover seeds, especially if seeds were stored under unknown conditions or under unfavorable storage conditions. Seed vigor testing is also used as indicator of the storage potential of a seed lot and in ranking various seed lots with different qualities. The vigour index is calculated using the equation given by (Ling et al. 2014) <doi:10.1038/srep05859>.
This package implements Multivariate ANalysis Of VAriance (MANOVA) parameters inference and test with regularization for semicontinuous high-dimensional data. The method can be applied also in presence of low-dimensional data. The p-value can be obtained through asymptotic distribution or using a permutation procedure. The package gives also the possibility to simulate this type of data. Method is described in Elena Sabbioni, Claudio Agostinelli and Alessio Farcomeni (2025) A regularized MANOVA test for semicontinuous high-dimensional data. Biometrical Journal, 67:e70054. DOI <doi:10.1002/bimj.70054>, arXiv DOI <doi:10.48550/arXiv.2401.04036>.
This package implements a likelihood ratio test and two pairwise standardized mean difference tests for testing equality of means against tree ordered alternatives in one-way ANOVA. The null hypothesis assumes all group means are equal, while the alternative assumes the control mean is less than or equal to each treatment mean with at least one strict inequality. Inputs are a list of numeric vectors (groups) and a significance level; outputs include the test statistic, critical value, and decision. Methods described in "Testing Against Tree Ordered Alternatives in One-way ANOVA" <doi:10.48550/arXiv.2507.17229>.
Computes the log likelihood for an inverse gamma stochastic volatility model using a closed form expression of the likelihood. The details of the computation of this closed form expression are given in Gonzalez and Majoni (2023) <http://rcea.org/RePEc/pdf/wp23-11.pdf> . The closed form expression is obtained for a stationary inverse gamma stochastic volatility model by marginalising out the volatility. This allows the user to obtain the maximum likelihood estimator for this non linear non Gaussian state space model. In addition, the user can obtain the estimates of the smoothed volatility using the exact smoothing distributions.
This package contains several tools for nonlinear regression analyses and general data analysis in biology and agriculture. Contains also datasets for practicing and teaching purposes. Supports the blog: Onofri (2024) "Fixing the bridge between biologists and statisticians" <https://www.statforbiology.com> and the book: Onofri (2024) "Experimental Methods in Agriculture" <https://www.statforbiology.com/_statbookeng/>. The blog is a collection of short articles aimed at improving the efficiency of communication between biologists and statisticians, as pointed out in Kozak (2016) <doi:10.1590/0103-9016-2015-0399>, spreading a better awareness of the potential usefulness, beauty and limitations of biostatistic.