Confidence intervals and point estimation for R under various parametric model assumptions; likelihood inference based on classical first-order approximations and higher-order asymptotic procedures.

Power calculations are a critical component of any research study to determine the minimum sample size necessary to detect differences between multiple groups. Here we present an R package, PASSED', that performs power and sample size calculations for the test of two-sample means or ratios with data following beta, gamma (Chang et al. (2011), <doi:10.1007/s00180-010-0209-1>), normal, Poisson (Gu et al. (2008), <doi:10.1002/bimj.200710403>), binomial, geometric, and negative binomial (Zhu and Lakkis (2014), <doi:10.1002/sim.5947>) distributions.

The plsdof package provides Degrees of Freedom estimates for Partial Least Squares (PLS) Regression. Model selection for PLS is based on various information criteria (aic, bic, gmdl) or on cross-validation. Estimates for the mean and covariance of the PLS regression coefficients are available. They allow the construction of approximate confidence intervals and the application of test procedures (Kramer and Sugiyama 2012 <doi:10.1198/jasa.2011.tm10107>). Further, cross-validation procedures for Ridge Regression and Principal Components Regression are available.

This package implements novel tools for estimating sample sizes needed for phylogenetic studies, including studies focused on estimating the probability of true pathogen transmission between two cases given phylogenetic linkage and studies focused on tracking pathogen variants at a population level. Methods described in Wohl, Giles, and Lessler (2021) and in Wohl, Lee, DiPrete, and Lessler (2023).

Estimation of the number of colonization events between islands of the same archipelago for a species. It uses rarefaction curves to control for both field and genetic sample sizes as it was described in Coello et al. (2022) <doi:10.1111/jbi.14341>.

Deduplicates datasets by retaining the most complete and informative records. Identifies duplicated entries based on a specified key column, calculates completeness scores for each row, and compares values within groups. When differences between duplicates exceed a user-defined threshold, records are split into unique IDs; otherwise, they are coalesced into a single, most complete entry. Returns a list containing the original duplicates, the split entries, and the final coalesced dataset. Useful for cleaning survey or administrative data where duplicated IDs may reflect minor data entry inconsistencies.

Calculation of the parametric, nonparametric confidence intervals for the difference or ratio of location parameters, nonparametric confidence interval for the Behrens-Fisher problem and for the difference, ratio and odds-ratio of binomial proportions for comparison of independent samples. Common wrapper functions to split data sets and apply confidence intervals or tests to these subsets. A by-statement allows calculation of CI separately for the levels of further factors. CI are not adjusted for multiplicity.

In a typical protein labelling procedure, proteins are chemically tagged with a functional group, usually at specific sites, then digested into peptides, which are then analyzed using matrix-assisted laser desorption ionization - time of flight mass spectrometry (MALDI-TOF MS) to generate peptide fingerprint. Relative to the control, peptides that are heavier by the mass of the labelling group are informative for sequence determination. Searching for peptides with such mass shifts, however, can be difficult. This package, designed to tackle this inconvenience, takes as input the mass list of two or multiple MALDI-TOF MS mass lists, and makes pairwise comparisons between the labeled groups vs. control, and restores centroid mass spectra with highlighted peaks of interest for easier visual examination. Particularly, peaks differentiated by the mass of the labelling group are defined as a â pairâ , those with equal masses as a â matchâ , and all the other peaks as a â mismatchâ .For more bioanalytical background information, refer to following publications: Jingjing Deng (2015) <doi:10.1007/978-1-4939-2550-6_19>; Elizabeth Chang (2016) <doi:10.7171/jbt.16-2702-002>.

Nonparametric density estimation for (hyper)spherical data by means of a parametrically guided kernel estimator (Alonso-Pena et al. (2024) <doi:10.1111/sjos.12737>. The package also allows the data-driven selection of the smoothing parameter and the representation of the estimated density for circular and spherical data. Estimators of the density without guide can also be obtained.

The document converter pandoc <https://pandoc.org/> is widely used in the R community. One feature of pandoc is that it can produce and consume JSON-formatted abstract syntax trees (AST). This allows to transform a given source document into JSON-formatted AST, alter it by so called filters and pass the altered JSON-formatted AST back to pandoc'. This package provides functions which allow to write such filters in native R code. Although this package is inspired by the Python package pandocfilters <https://github.com/jgm/pandocfilters/>, it provides additional convenience functions which make it simple to use the pandocfilters package as a report generator. Since pandocfilters inherits most of it's functionality from pandoc it can create documents in many formats (for more information see <https://pandoc.org/>) but is also bound to the same limitations as pandoc'.

Translating messages in R packages is managed using the po top-level directory and the gettext program. This package provides some helper functions for building this support in R packages, e.g. common validation & I/O tasks.

This package provides functions to process, format and store ActiGraph GT1M and GT3X accelerometer data.

This package implements (1) panel cointegration rank tests, (2) estimators for panel vector autoregressive (VAR) models, and (3) identification methods for panel structural vector autoregressive (SVAR) models as described in the accompanying vignette. The implemented functions allow to account for cross-sectional dependence and for structural breaks in the deterministic terms of the VAR processes. Among the large set of functions, particularly noteworthy are those that implement (1) the correlation-augmented inverse normal test on the cointegration rank by Arsova and Oersal (2021, <doi:10.1016/j.ecosta.2020.05.002>), (2) the two-step estimator for pooled cointegrating vectors by Breitung (2005, <doi:10.1081/ETC-200067895>), and (3) the pooled identification based on independent component analysis by Herwartz and Wang (2024, <doi:10.1002/jae.3044>).

This package performs elementary probability calculations on finite sample spaces, which may be represented by data frames or lists. This package is meant to rescue some widely used functions from the archived prob package (see <https://cran.r-project.org/src/contrib/Archive/prob/>). Functionality includes setting up sample spaces, counting tools, defining probability spaces, performing set algebra, calculating probability and conditional probability, tools for simulation and checking the law of large numbers, adding random variables, and finding marginal distributions. Characteristic functions for all base R distributions are included.

To find the certainty of dominance interactions with indirect interactions being considered.

Can be used to carry out permutation based gene expression pathway analysis. This work was supported by a National Institute of Allergy and Infectious Disease/National Institutes of Health contract (No. HHSN272200900059C).

This package provides a PEP, or Portable Encapsulated Project, is a dataset that subscribes to the PEP structure for organizing metadata. It is written using a simple YAML + CSV format, it is your one-stop solution to metadata management across data analysis environments. This package reads this standardized project configuration structure into R. Described in Sheffield et al. (2021) <doi:10.1093/gigascience/giab077>.

Identification of the most appropriate pharmacotherapy for each patient based on genomic alterations is a major challenge in personalized oncology. PANACEA is a collection of personalized anti-cancer drug prioritization approaches utilizing network methods. The methods utilize personalized "driverness" scores from driveR to rank drugs, mapping these onto a protein-protein interaction network. The "distance-based" method scores each drug based on these scores and distances between drugs and genes to rank given drugs. The "RWR" method propagates these scores via a random-walk with restart framework to rank the drugs. The methods are described in detail in Ulgen E, Ozisik O, Sezerman OU. 2023. PANACEA: network-based methods for pharmacotherapy prioritization in personalized oncology. Bioinformatics <doi:10.1093/bioinformatics/btad022>.

R has no built-in pointer functionality. The pointr package fills this gap and lets you create pointers to R objects, including subsets of dataframes. This makes your R code more readable and maintainable.

This package provides function declarations and inline function definitions that facilitate cleaning strings in C++ code before passing them to R.

Compute the price of different types of call using different methods. The types available are Vanilla European Calls, Vanilla American Calls and American Digital Calls. Available methods are Montecarlo Simulation, Montecarlo Simulation with Antithetic Variates, Black-Scholes and the Binary Tree.

Create sliders from left, right, top and bottom which may include any html or Shiny input or output.

An extensible repository of accurate, up-to-date functions to score commonly used patient-reported outcome (PRO), quality of life (QOL), and other psychometric and psychological measures. PROscorer', together with the PROscorerTools package, is a system to facilitate the incorporation of PRO measures into research studies and clinical settings in a scientifically rigorous and reproducible manner. These packages and their vignettes are intended to help establish and promote best practices for scoring PRO and PRO-like measures in research. The PROscorer Instrument Descriptions vignette contains descriptions of each instrument scored by PROscorer', complete with references. These instrument descriptions are suitable for inclusion in formal study protocol documents, grant proposals, and manuscript Method sections. Each PROscorer function is composed of helper functions from the PROscorerTools package, and users are encouraged to contribute new functions to PROscorer'. More scoring functions are currently in development and will be added in future updates.

Calculates multivariate analysis of variance based on permutations and some associated pictorial representations. The pictorial representation is based on the principal coordinates of the group means. There are some original results that will be published soon.