The Prognostic Regression Offsets with Propagation of ERrors (for Treatment Effect Estimation) package facilitates direct adjustment for experiments and observational studies that is compatible with a range of study designs and covariance adjustment strategies. It uses explicit specification of clusters, blocks and treatment allocations to furnish probability of assignment-based weights targeting any of several average treatment effect parameters, and for standard error calculations reflecting these design parameters. For covariance adjustment of its Hajek and (one-way) fixed effects estimates, it enables offsetting the outcome against predictions from a dedicated covariance model, with standard error calculations propagating error as appropriate from the covariance model.

Jointly segment several ChIP-seq samples to find the peaks which are the same and different across samples. The fast approximate maximum Poisson likelihood algorithm is described in "PeakSegJoint: fast supervised peak detection via joint segmentation of multiple count data samples" <doi:10.48550/arXiv.1506.01286> by TD Hocking and G Bourque.

This package provides tools for retrieving and analyzing air quality data from PurpleAir sensors through their API. Functions enable downloading historical measurements, accessing sensor metadata, and managing API request limitations through chunked data retrieval. For more information about the PurpleAir API, see <https://api.purpleair.com/>.

This package provides beginner friendly framework to analyse population genetic data. Based on adegenet objects it uses knitr to create comprehensive reports on spatial genetic data. For detailed information how to use the package refer to the comprehensive tutorials or visit <http://www.popgenreport.org/>.

To Simplify the time consuming and error prone task of assembling complex data sets for non-linear mixed effects modeling. Users are able to select from different absorption processes such as zero and first order, or a combination of both. Furthermore, data sets containing data from several entities, responses, and covariates can be simultaneously assembled.

This package provides several measures ((dis)similarity, distance/metric, correlation, entropy) for comparing two partitions of the same set of objects. The different measures can be assigned to three different classes: Pair comparison (containing the famous Jaccard and Rand indices), set based, and information theory based. Many of the implemented measures can be found in Albatineh AN, Niewiadomska-Bugaj M and Mihalko D (2006) <doi:10.1007/s00357-006-0017-z> and Meila M (2007) <doi:10.1016/j.jmva.2006.11.013>. Partitions are represented by vectors of class labels which allow a straightforward integration with existing clustering algorithms (e.g. kmeans()). The package is mostly based on the S4 object system.

Data from All the World's Primates relational SQL database and other tabular datasets are made available via drivers and connection functions. Additionally we provide several functions and examples to facilitate the merging and aggregation of these tabular inputs.

Fits right-truncated meta-analysis (RTMA), a bias correction for the joint effects of p-hacking (i.e., manipulation of results within studies to obtain significant, positive estimates) and traditional publication bias (i.e., the selective publication of studies with significant, positive results) in meta-analyses [see Mathur MB (2022). "Sensitivity analysis for p-hacking in meta-analyses." <doi:10.31219/osf.io/ezjsx>.]. Unlike publication bias alone, p-hacking that favors significant, positive results (termed "affirmative") can distort the distribution of affirmative results. To bias-correct results from affirmative studies would require strong assumptions on the exact nature of p-hacking. In contrast, joint p-hacking and publication bias do not distort the distribution of published nonaffirmative results when there is stringent p-hacking (e.g., investigators who hack always eventually obtain an affirmative result) or when there is stringent publication bias (e.g., nonaffirmative results from hacked studies are never published). This means that any published nonaffirmative results are from unhacked studies. Under these assumptions, RTMA involves analyzing only the published nonaffirmative results to essentially impute the full underlying distribution of all results prior to selection due to p-hacking and/or publication bias. The package also provides diagnostic plots described in Mathur (2022).

An implementation of two functions that estimate values for percentiles from an ordered categorical variable as described by Reardon (2011, isbn:978-0-87154-372-1). One function estimates percentile differences from two percentiles while the other returns the values for every percentile from 1 to 100.

This package provides a semi-parametric estimation method for the Cox model with left-truncated data using augmented information from the marginal of truncation times.

Optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix. This package was developed for pharmacometric problems, and examples and predefined models are available for these types of systems. The methods are described in Nyberg et al. (2012) <doi:10.1016/j.cmpb.2012.05.005>, and Foracchia et al. (2004) <doi:10.1016/S0169-2607(03)00073-7>.

This package provides a framework for creating interactive figures for data exploration. All plots are automatically linked and support several kinds of interactive features, including selection, zooming, panning, and parameter manipulation. The figures can be interacted with either manually, using a mouse and a keyboard, or by running code from inside an active R session.

Enables user to perform the following: 1. Roll n number of die/dice (roll()). 2. Toss n number of coin(s) (toss()). 3. Play the game of Rock, Paper, Scissors. 4. Choose n number of card(s) from a pack of 52 playing cards (Joker optional).

This package provides tools for modelling populations and demography using matrix projection models, with deterministic and stochastic model implementations. Includes population projection, indices of short- and long-term population size and growth, perturbation analysis, convergence to stability or stationarity, and diagnostic and manipulation tools.

It creates a lattice plot to visualize panel or longitudinal data. The observed values are plotted as dots and the fitted values as lines, both against time. The plot is customizable and easy to edit, even if you do not know how to construct a lattice plot from scratch.

Optogenetics is a new tool to study neuronal circuits that have been genetically modified to allow stimulation by flashes of light. This package implements the methodological framework, Point-process Response model for Optogenetics (PRO), for analyzing data from these experiments. This method provides explicit nonlinear transformations to link the flash point-process with the spiking point-process. Such response functions can be used to provide important and interpretable scientific insights into the properties of the biophysical process that governs neural spiking in response to optogenetic stimulation.

This package implements a range of facilities for post-hoc analysis and summarizing linear models, generalized linear models and generalized linear mixed models, including grouping and clustering via pairwise comparisons using graph representations and efficient algorithms for finding maximal cliques of a graph. Includes also non-parametric toos for post-hoc analysis. It has S3 methods for printing summarizing, and producing plots, line and barplots suitable for post-hoc analyses.

This toolkit is designed for manipulation and analysis of peptides. It provides functionalities to assist researchers in peptide engineering and proteomics. Users can manipulate peptides by adding amino acids at every position, count occurrences of each amino acid at each position, and transform amino acid counts based on probabilities. The package offers functionalities to select the best versus the worst peptides and analyze these peptides, which includes counting specific residues, reducing peptide sequences, extracting features through One Hot Encoding (OHE), and utilizing Quantitative Structure-Activity Relationship (QSAR) properties (based in the package Peptides by Osorio et al. (2015) <doi:10.32614/RJ-2015-001>). This package is intended for both researchers and bioinformatics enthusiasts working on peptide-based projects, especially for their use with machine learning.

This package contains functions to fit proportional hazards (PH) model to partly interval-censored (PIC) data (Pan et al. (2020) <doi:10.1177/0962280220921552>), PH model with spatial frailty to spatially dependent PIC data (Pan and Cai (2021) <doi:10.1080/03610918.2020.1839497>), and mixed effects PH model to clustered PIC data. Each random intercept/random effect can follow both a normal prior and a Dirichlet process mixture prior. It also includes the corresponding functions for general interval-censored data.

Consists of custom wrapper functions using packages openxlsx', flextable', and officer to create highly formatted MS office friendly output of your data frames. These viewer friendly outputs are intended to match expectations of professional looking presentations in business and consulting scenarios. The functions are opinionated in the sense that they expect the input data frame to have certain properties in order to take advantage of the automated formatting.

This package provides a tidyverse'-style interface to the Brazilian Central Bank (<https://www.bcb.gov.br>) PIX Open Data API <https://olinda.bcb.gov.br/olinda/servico/Pix_DadosAbertos/versao/v1/aplicacao#!/recursos>. Retrieve statistics on PIX keys, transactions by municipality, and monthly transaction summaries. All functions return tibbles and support OData query parameters for filtering, selecting, and ordering data.

Calculates multivariate analysis of variance based on permutations and some associated pictorial representations. The pictorial representation is based on the principal coordinates of the group means. There are some original results that will be published soon.

This package provides a convenient framework for aggregating and disaggregating continuously varying parameters (for example, case fatality ratio, with age) for proper parametrization of lower-resolution compartmental models (for example, with broad age categories) and subsequent upscaling of model outputs to high resolution (for example, as needed when calculating age-sensitive measures like years-life-lost).

Identification, model fitting and estimation for time series with periodic structure. Additionally, procedures for simulation of periodic processes and real data sets are included. Hurd, H. L., Miamee, A. G. (2007) <doi:10.1002/9780470182833> Box, G. E. P., Jenkins, G. M., Reinsel, G. (1994) <doi:10.1111/jtsa.12194> Brockwell, P. J., Davis, R. A. (1991, ISBN:978-1-4419-0319-8) Bretz, F., Hothorn, T., Westfall, P. (2010, ISBN: 9780429139543) Westfall, P. H., Young, S. S. (1993, ISBN:978-0-471-55761-6) Bloomfield, P., Hurd, H. L.,Lund, R. (1994) <doi:10.1111/j.1467-9892.1994.tb00181.x> Dehay, D., Hurd, H. L. (1994, ISBN:0-7803-1023-3) Vecchia, A. (1985) <doi:10.1080/00401706.1985.10488076> Vecchia, A. (1985) <doi:10.1111/j.1752-1688.1985.tb00167.x> Jones, R., Brelsford, W. (1967) <doi:10.1093/biomet/54.3-4.403> Makagon, A. (1999) <https://www.math.uni.wroc.pl/~pms/files/19.2/Article/19.2.5.pdf> Sakai, H. (1989) <doi:10.1111/j.1467-9892.1991.tb00069.x> Gladyshev, E. G. (1961) <https://www.mathnet.ru/php/archive.phtml?wshow=paper&jrnid=dan&paperid=24851> Ansley (1979) <doi:10.1093/biomet/66.1.59> Hurd, H. L., Gerr, N. L. (1991) <doi:10.1111/j.1467-9892.1991.tb00088.x>.