This package provides a nonparametric, multicore-capable plausible naive Bayes classifier based on the Pareto density estimation (PDE) featuring a plausible approach to a pitfall in the Bayesian theorem covering low evidence cases. Stier, Q., Hoffmann, J., and Thrun, M.C.: "Classifying with the Fine Structure of Distributions: Leveraging Distributional Information for Robust and Plausible Naive Bayes" (2026), Machine Learning and Knowledge Extraction (MAKE), <DOI:10.3390/make8010013>.

This package implements piecewise structural equation modeling from a single list of structural equations, with new methods for non-linear, latent, and composite variables, standardized coefficients, query-based prediction and indirect effects. See <http://jslefche.github.io/piecewiseSEM/> for more.

Partial Least Squares Path Modeling (PLS-PM), Tenenhaus, Esposito Vinzi, Chatelin, Lauro (2005) <doi:10.1016/j.csda.2004.03.005>, analysis for both metric and non-metric data, as well as REBUS analysis, Esposito Vinzi, Trinchera, Squillacciotti, and Tenenhaus (2008) <doi:10.1002/asmb.728>.

This package provides a set of raw datasets used to create SDTM domains in pharmaversesdtm package.

This package provides a simple interface in the form of R6 classes for executing tasks in parallel, tracking their progress, and displaying accurate progress bars.

This package provides tools for downloading, reading and analyzing the National Survey of Demographic and Health - PNDS, a household survey from Brazilian Institute of Geography and Statistics - IBGE. The data must be downloaded from the official website <https://www.ibge.gov.br/>. Further analysis must be made using package survey'.

Fits successive Lasso models for several blocks of (omics) data with different priorities and takes the predicted values as an offset for the next block. Also offers options to deal with block-wise missingness in multi-omics data.

Defines a data structure for profiler data, and methods to read and write from the Rprof and pprof file formats.

This toolkit is designed for manipulation and analysis of peptides. It provides functionalities to assist researchers in peptide engineering and proteomics. Users can manipulate peptides by adding amino acids at every position, count occurrences of each amino acid at each position, and transform amino acid counts based on probabilities. The package offers functionalities to select the best versus the worst peptides and analyze these peptides, which includes counting specific residues, reducing peptide sequences, extracting features through One Hot Encoding (OHE), and utilizing Quantitative Structure-Activity Relationship (QSAR) properties (based in the package Peptides by Osorio et al. (2015) <doi:10.32614/RJ-2015-001>). This package is intended for both researchers and bioinformatics enthusiasts working on peptide-based projects, especially for their use with machine learning.

R API for Pathling', a tool for querying and transforming electronic health record data that is represented using the Fast Healthcare Interoperability Resources (FHIR) standard - see <https://pathling.csiro.au/docs>.

Make statistical inference on the probability of being in response, the duration of response, and the cumulative response rate up to a given time point. The method can be applied to analyze phase II randomized clinical trials with the endpoints being time to treatment response and time to progression or death.

It estimates power and sample size for Partial Least Squares-based methods described in Andreella, et al., (2024), <doi:10.48550/arXiv.2403.10289>.

Efficient algorithm for solving PU (Positive and Unlabeled) problem in low or high dimensional setting with lasso or group lasso penalty. The algorithm uses Maximization-Minorization and (block) coordinate descent. Sparse calculation and parallel computing are supported for the computational speed-up. See Hyebin Song, Garvesh Raskutti (2018) <doi:10.48550/arXiv.1711.08129>.

Computes probability-scale residuals and residual correlations for continuous, ordinal, binary, count, and time-to-event data Qi Liu, Bryan Shepherd, Chun Li (2020) <doi:10.18637/jss.v094.i12>.

An R interface to pikchr (<https://pikchr.org>, pronounced â pictureâ ), a PIC'-like markup language for creating diagrams within technical documentation. Originally developed by Brian Kernighan, PIC has been adapted into pikchr by D. Richard Hipp, the creator of SQLite'. pikchr is designed to be embedded in fenced code blocks of Markdown or other documentation markup languages, making it ideal for generating diagrams in text-based formats. This package allows R users to seamlessly integrate the descriptive syntax of pikchr for diagram creation directly within the R environment.

This package provides functions to compute the potential model as defined by Stewart (1941) <doi:10.1126/science.93.2404.89>. Several options are available to customize the model, such as the possibility to fine-tune the distance friction functions or to use custom distance matrices. Some computations are parallelized to improve their efficiency.

Run population simulations using an Individual-Based Model (IBM) compiled in C.

Joint frailty models have been widely used to study the associations between recurrent events and a survival outcome. However, existing joint frailty models only consider one or a few recurrent events and cannot deal with high-dimensional recurrent events. This package can be used to fit our recently developed penalized joint frailty model that can handle high-dimensional recurrent events. Specifically, an adaptive lasso penalty is imposed on the parameters for the effects of the recurrent events on the survival outcome, which allows for variable selection. Also, our algorithm is computationally efficient, which is based on the Gaussian variational approximation method.

Parse messy geographic coordinates from various character formats to decimal degree numeric values. Parse coordinates into their parts (degree, minutes, seconds); calculate hemisphere from coordinates; pull out individually degrees, minutes, or seconds; add and subtract degrees, minutes, and seconds. C++ code herein originally inspired from code written by Jeffrey D. Bogan, but then completely re-written.

For a multivariate dataset with independent Poisson measurement error, calculates principal components of transformed latent Poisson means. T. Kenney, T. Huang, H. Gu (2019) <arXiv:1904.11745>.

It provides utility functions for investigating changes within R packages. The pkgInfo() function extracts package information such as exported and non-exported functions as well as their arguments. The pkgDiff() function compares this information for two versions of a package and creates a diff file viewable in a browser.

This function fits a reversible jump Bayesian piecewise exponential model that also includes the intensity of each event considered along with the rate of events.

Create and customize interactive phylogenetic trees using the phylocanvas JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps, and in R Markdown documents. See <http://phylocanvas.org/> for more information on the phylocanvas library.

An application to calculate a patient's pretest probability (PTP) for obstructive Coronary Artery Disease (CAD) from a collection of guidelines or studies. Guidelines usually comes from the American Heart Association (AHA), American College of Cardiology (ACC) or European Society of Cardiology (ESC). Examples of PTP scores that comes from studies are the 2020 Winther et al. basic, Risk Factor-weighted Clinical Likelihood (RF-CL) and Coronary Artery Calcium Score-weighted Clinical Likelihood (CACS-CL) models <doi:10.1016/j.jacc.2020.09.585>, 2019 Reeh et al. basic and clinical models <doi:10.1093/eurheartj/ehy806> and 2017 Fordyce et al. PROMISE Minimal-Risk Tool <doi:10.1001/jamacardio.2016.5501>. As diagnosis of CAD involves a costly and invasive coronary angiography procedure for patients, having a reliable PTP for CAD helps doctors to make better decisions during patient management. This ensures high risk patients can be diagnosed and treated early for CAD while avoiding unnecessary testing for low risk patients.