MetaboCoreUtils defines metabolomics-related core functionality provided as low-level functions to allow a data structure-independent usage across various R packages. This includes functions to calculate between ion (adduct) and compound mass-to-charge ratios and masses or functions to work with chemical formulas. The package provides also a set of adduct definitions and information on some commercially available internal standard mixes commonly used in MS experiments.

This package lets you compute and plot predictions, slopes, marginal means, and comparisons (contrasts, risk ratios, odds, etc.) for over 100 classes of statistical and machine learning models in R. Conduct linear and non-linear hypothesis tests, or equivalence tests. Calculate uncertainty estimates using the delta method, bootstrapping, or simulation-based inference. Details can be found in Arel-Bundock, Greifer, and Heiss (2024) <doi:10.18637/jss.v111.i09>.

This package provides classes to implement, analyze and plot cohort life tables for actuarial calculations. Birth-year dependent cohort mortality tables using a yearly trend to extrapolate from a base year are implemented, as well as period life table, cohort life tables using an age shift, and merged life tables. Additionally, several data sets from various countries are included to provide widely-used tables out of the box.

Easily use Blueprint', the popular React library from Palantir, in your Shiny app. Blueprint provides a rich set of UI components for creating visually appealing applications and is optimized for building complex, data-dense web interfaces. This package provides most components from the underlying library, as well as special wrappers for some components to make it easy to use them in R without writing JavaScript code.

User tools for working with The STOICH (Stoichiometric Traits of Organisms in their Chemical Habitats) Project database <https://snr-stoich.unl.edu/>. This package is designed to aid in data discovery, filtering, pairing water samples with organism samples, and merging data tables to assist users in preparing data for analyses. For additional examples see "Additional Examples" and the readme file at <https://github.com/STOICH-project/STOICH-utilities>.

The wolfSSL embedded SSL library (formerly CyaSSL) is an SSL/TLS library written in ANSI C and targeted for embedded, RTOS, and resource-constrained environments - primarily because of its small size, speed, and feature set. wolfSSL supports industry standards up to the current TLS 1.3 and DTLS 1.2, is up to 20 times smaller than OpenSSL, and offers progressive ciphers such as ChaCha20, Curve25519, NTRU, and Blake2b.

Efficient implementations of multiple exact and approximate methods as described in Hong (2013) <doi:10.1016/j.csda.2012.10.006>, Biscarri, Zhao & Brunner (2018) <doi:10.1016/j.csda.2018.01.007> and Zhang, Hong & Balakrishnan (2018) <doi:10.1080/00949655.2018.1440294> for computing the probability mass, cumulative distribution and quantile functions, as well as generating random numbers for both the ordinary and generalised Poisson binomial distribution.

Identifies, filters and exports sex linked markers using SNP (single nucleotide polymorphism) data. To install the other packages, we recommend to install the dartRverse package, that supports the installation of all packages in the dartRverse'. If you want understand the applied rational to identify sexlinked markers and/or want to cite dartR.sexlinked', you find the information by typing citation('dartR.sexlinked') in the console.

This package provides functions for modelling microbial inactivation under isothermal or dynamic conditions. The calculations are based on several mathematical models broadly used by the scientific community and industry. Functions enable to make predictions for cases where the kinetic parameters are known. It also implements functions for parameter estimation for isothermal and dynamic conditions. The model fitting capabilities include an Adaptive Monte Carlo method for a Bayesian approach to parameter estimation.

Estimate the parameters of multivariate endogenous switching and sample selection models using methods described in Newey (2009) <doi:10.1111/j.1368-423X.2008.00263.x>, E. Kossova, B. Potanin (2018) <https://ideas.repec.org/a/ris/apltrx/0346.html>, E. Kossova, L. Kupriianova, B. Potanin (2020) <https://ideas.repec.org/a/ris/apltrx/0391.html> and E. Kossova, B. Potanin (2022) <https://ideas.repec.org/a/ris/apltrx/0455.html>.

Enables deploying configuration file-based shiny apps with minimal programming for interactive exploration and analysis showcase of molecular expression data. For exploration, supports visualization of correlations between rows of an expression matrix and a table of observations, such as clinical measures, and comparison of changes in expression over time. For showcase, enables visualizing the results of differential expression from package such as limma', co-expression modules from WGCNA and lower dimensional projections.

Two-step and maximum likelihood estimation of Heckman-type sample selection models: standard sample selection models (Tobit-2), endogenous switching regression models (Tobit-5), sample selection models with binary dependent outcome variable, interval regression with sample selection (only ML estimation), and endogenous treatment effects models. These methods are described in the three vignettes that are included in this package and in econometric textbooks such as Greene (2011, Econometric Analysis, 7th edition, Pearson).

This package provides a collection of functions to plot acid/base titration curves (pH vs. volume of titrant), complexation titration curves (pMetal vs. volume of EDTA), redox titration curves (potential vs.volume of titrant), and precipitation titration curves (either pAnalyte or pTitrant vs. volume of titrant). Options include the titration of mixtures, the ability to overlay two or more titration curves, and the ability to show equivalence points.

IsoCorrectoRGUI is a Graphical User Interface for the IsoCorrectoR package. IsoCorrectoR performs the correction of mass spectrometry data from stable isotope labeling/tracing metabolomics experiments with regard to natural isotope abundance and tracer impurity. Data from both MS and MS/MS measurements can be corrected (with any tracer isotope: 13C, 15N, 18O...), as well as high resolution MS data from multiple-tracer experiments (e.g. 13C and 15N used simultaneously).

This package provides an easy to use implementation of life expectancy decomposition formulas for age bands, derived from Ponnapalli, K. (2005). A comparison of different methods for decomposition of changes in expectation of life at birth and differentials in life expectancy at birth. Demographic Research, 12, pp.141â 172. <doi:10.4054/demres.2005.12.7> In addition, there is a decomposition function for disease cause breakdown and a couple helpful plot functions.

The GSEABenchmarkeR package implements an extendable framework for reproducible evaluation of set- and network-based methods for enrichment analysis of gene expression data. This includes support for the efficient execution of these methods on comprehensive real data compendia (microarray and RNA-seq) using parallel computation on standard workstations and institutional computer grids. Methods can then be assessed with respect to runtime, statistical significance, and relevance of the results for the phenotypes investigated.

Package to query the Twitter Academic Research Product Track, providing access to full-archive search and other v2 API endpoints. Functions are written with academic research in mind. They provide flexibility in how the user wishes to store collected data, and encourage regular storage of data to mitigate loss when collecting large volumes of tweets. They also provide workarounds to manage and reshape the format in which data is provided on the client side.

This package implements three test procedures using bootstrap resampling techniques for assessing treatment effects in one-way ANOVA models with unequal variances (heteroscedasticity). It includes a parametric bootstrap likelihood ratio test (PB_LRT()), a pairwise parametric bootstrap mean test (PPBMT()), and a Rademacher wild pairwise non-parametric bootstrap test (RWPNPBT()). These methods provide robust alternatives to classical ANOVA and standard pairwise comparisons when the assumption of homogeneity of variances is violated.

The Concordance Test is a non-parametric method for testing whether two o more samples originate from the same distribution. It extends the Kendall Tau correlation coefficient when there are only two groups. For details, see Alcaraz J., Anton-Sanchez L., Monge J.F. (2022) The Concordance Test, an Alternative to Kruskal-Wallis Based on the Kendall-tau Distance: An R Package. The R Journal 14, 26â 53 <doi:10.32614/RJ-2022-039>.

Means to predict process flow, such as process outcome, next activity, next time, remaining time, and remaining trace. Off-the-shelf predictive models based on the concept of Transformers are provided, as well as multiple way to customize the models. This package is partly based on work described in Zaharah A. Bukhsh, Aaqib Saeed, & Remco M. Dijkman. (2021). "ProcessTransformer: Predictive Business Process Monitoring with Transformer Network" <doi:10.48550/arXiv.2104.00721>.

Identification of the most likely gene or genes through which variation at a given genomic locus in the human genome acts. The most basic functionality assumes that the closer gene is to the input locus, the more likely the gene is to be causative. Additionally, any empirical data that links genomic regions to genes (e.g. eQTL or genome conformation data) can be used if it is supplied in the UCSC .BED file format.

Helping psychologists and other behavioural scientists to analyze mouse movement (and other 2-D trajectory) data. Bundles together several functions that compute spatial measures (e.g., maximum absolute deviation, area under the curve, sample entropy) or provide a shorthand for procedures that are frequently used (e.g., time normalization, linear interpolation, extracting initiation and movement times). For more information on these dependent measures, see Wirth et al. (2020) <doi:10.3758/s13428-020-01409-0>.

Programs for detecting and cleaning outliers in single time series and in time series from homogeneous and heterogeneous databases using an Orthogonal Greedy Algorithm (OGA) for saturated linear regression models. The programs implement the procedures presented in the paper entitled "Efficient Outlier Detection for Large Time Series Databases" by Pedro Galeano, Daniel Peña and Ruey S. Tsay (2026), working paper, Universidad Carlos III de Madrid. Version 1.1.2 fixes one bug.

Clusters state sequences and weighted data. It provides an optimized weighted PAM algorithm as well as functions for aggregating replicated cases, computing cluster quality measures for a range of clustering solutions, sequence analysis typology validation using parametric bootstraps and plotting (fuzzy) clusters of state sequences. It further provides a fuzzy and crisp CLARA algorithm to cluster large database with sequence analysis, and a methodological framework for Robustness Assessment of Regressions using Cluster Analysis Typologies (RARCAT).