This package provides utilities for processing of Oxy-Bisulfite microarray data (e.g. via the Illumina Infinium platform, <http://www.illumina.com>) with tandem arrays, one using conventional bisulfite conversion, the other using oxy-bisulfite conversion.

Picks the suitable cell types in spatial and scRNA-seq data using shrinkage methods. The package includes curated reference gene expression profiles for human and mouse cell types, facilitating immediate application to common spatial transcriptomics or scRNA datasets. Additionally, users can input custom reference data to support tissue- or experiment-specific analyses.

Model mixed integer linear programs in an algebraic way directly in R. The model is solver-independent and thus offers the possibility to solve a model with different solvers. It currently only supports linear constraints and objective functions. See the ompr website <https://dirkschumacher.github.io/ompr/> for more information, documentation and examples.

Characterization of distribution data on the surface of a sphere. The primary group of these metrics describe the extent of a distribution, geographic ranges. The calculation of geographic descriptors can be executed using point coordinate data, vector polygons, as well as cells on a discretized sphere. Besides using spherical implementations, the package offers the exploration of partial results for visual diagnostics.

This package implements multiple existing open-source algorithms for coding cause of death from verbal autopsies. The methods implemented include InterVA4 by Byass et al (2012) <doi:10.3402/gha.v5i0.19281>, InterVA5 by Byass at al (2019) <doi:10.1186/s12916-019-1333-6>, InSilicoVA by McCormick et al (2016) <doi:10.1080/01621459.2016.1152191>, NBC by Miasnikof et al (2015) <doi:10.1186/s12916-015-0521-2>, and a replication of Tariff method by James et al (2011) <doi:10.1186/1478-7954-9-31> and Serina, et al. (2015) <doi:10.1186/s12916-015-0527-9>. It also provides tools for data manipulation tasks commonly used in Verbal Autopsy analysis and implements easy graphical visualization of individual and population level statistics. The NBC method is implemented by the nbc4va package that can be installed from <https://github.com/rrwen/nbc4va>. Note that this package was not developed by authors affiliated with the Institute for Health Metrics and Evaluation and thus unintentional discrepancies may exist in the implementation of the Tariff method.

This package provides functionalities and data structures to retrieve, analyze and visualize aviation data. It includes a client interface to the OpenSky API <https://opensky-network.org>. It allows retrieval of flight information, as well as aircraft state vectors.

Interact seamlessly with Open Target GraphQL endpoint to query and retrieve tidy data tables, facilitating the analysis of gene, disease, drug, and genetic data. For more information about the Open Target API (<https://platform.opentargets.org/api>).

Maps of Australian coastline and administrative regions. Data can be drawn or accessed directly as simple features objects. Includes simple functions for country or state maps of Australia and in-built data sets of administrative regions from the Australian Bureau of Statistics <https://www.abs.gov.au/>. Layers include electoral divisions and local government areas, simplified from the original sources but with sufficient detail to allow mapping of a local municipality.

Provide principally an eponymic function that numerically computes the Le Cam's one-step estimator for an independent and identically distributed sample. One-step estimation is asymptotically efficient (see L. Le Cam (1956) <https://projecteuclid.org/euclid.bsmsp/1200501652>) and can be computed faster than the maximum likelihood estimator for large observation samples, see e.g. Brouste et al. (2021) <doi:10.32614/RJ-2021-044>.

DNA methylation is an important epigenetic process that regulates gene activity through chemical modifications of DNA without changing its sequence. OpEnCAST is a plant-specific ensemble-based prediction package that identifies 4mC, 5mC and 6mA methylation sites directly from DNA sequences. It combines multiple machine learning algorithms trained on monocot (Oryza sp.) and dicot (Arabidopsis sp.) reference models to deliver accurate predictions. This methodology is being inspired by the ensemble algorithm for methylation prediction developed by Wang et al. (2022) <doi:10.1186/s12859-022-04756-1>.

Helps to create ggplot2 charts in the style used by the National Road Safety Observatory (ONSV). The package includes functions to customize ggplot2 objects with new theme and colors.

This package implements the Bayesian online changepoint detection method by Adams and MacKay (2007) <arXiv:0710.3742> for univariate or multivariate data. Gaussian and Poisson probability models are implemented. Provides post-processing functions with alternative ways to extract changepoints.

Runtime OpenCL support for R package developers: probe hardware and drivers, load and concatenate kernel sources, and manage dependency-annotated .cl libraries, so packages like nmathopencl and other ported libraries can offer GPU acceleration without each re-implementing and related helpers. Vignettes illustrate integration with suggested package nmathopencl and with downstream applications such as glmbayes'; production kernels for those applications ship in those packages rather than here.

This package provides analyse, interpret and understand noise pollution data. Data are typically regular time series measured with sound meter. The package is partially described in Fogola, Grasso, Masera and Scordino (2023, <DOI:10.61782/fa.2023.0063>).

Generate systems of ordinary differential equations (ODE) and integrate them, using a domain specific language (DSL). The DSL uses R's syntax, but compiles to C in order to efficiently solve the system. A solver is not provided, but instead interfaces to the packages deSolve and dde are generated. With these, while solving the differential equations, no allocations are done and the calculations remain entirely in compiled code. Alternatively, a model can be transpiled to R for use in contexts where a C compiler is not present. After compilation, models can be inspected to return information about parameters and outputs, or intermediate values after calculations. odin is not targeted at any particular domain and is suitable for any system that can be expressed primarily as mathematical expressions. Additional support is provided for working with delays (delay differential equations, DDE), using interpolated functions during interpolation, and for integrating quantities that represent arrays.

Estimates ordered probit switching regression models - a Heckman type selection model with an ordinal selection and continuous outcomes. Different model specifications are allowed for each treatment/regime. For more details on the method, see Wang & Mokhtarian (2024) <doi:10.1016/j.tra.2024.104072> or Chiburis & Lokshin (2007) <doi:10.1177/1536867X0700700202>.

Users can build a single shiny app for exploring population characterization, population-level causal effect estimation, and patient-level prediction results generated via the R analyses packages in HADES (see <https://ohdsi.github.io/Hades/>). Learn more about OhdsiShinyAppBuilder at <https://ohdsi.github.io/OhdsiShinyAppBuilder/>.

Data integration Web application for biobanks by OBiBa'. Opal is the core database application for biobanks. Participant data, once collected from any data source, must be integrated and stored in a central data repository under a uniform model. Opal is such a central repository. It can import, process, validate, query, analyze, report, and export data. Opal is typically used in a research center to analyze the data acquired at assessment centres. Its ultimate purpose is to achieve seamless data-sharing among biobanks. This Opal client allows to interact with Opal web services and to perform operations on the R server side. DataSHIELD administration tools are also provided.

Summarizes the taxonomic composition, diversity contribution of the rare and abundant community by using OTU (operational taxonomic unit) table which was generated by analyzing pipeline of QIIME or mothur'. The rare biosphere in this package is subset by the relative abundance threshold (for details about rare biosphere please see Lynch and Neufeld (2015) <doi:10.1038/nrmicro3400>).

This package provides functions for implementing different versions of the OSCV method in the kernel regression and density estimation frameworks. The package mainly supports the following articles: (1) Savchuk, O.Y., Hart, J.D. (2017). Fully robust one-sided cross-validation for regression functions. Computational Statistics, <doi:10.1007/s00180-017-0713-7> and (2) Savchuk, O.Y. (2017). One-sided cross-validation for nonsmooth density functions, <arXiv:1703.05157>.

Bindings, methods, and tuners for using ordinal classification models with the parsnip and dials packages. These include the regularized elastic net ordinal regression of Wurm, Hanlon, and Rathouz (2021) <doi:10.18637/jss.v099.i06> in ordinalNet', the ordinal classification trees of Galimberti, Soffritti, and Di Maso (2012) <doi:10.18637/jss.v047.i10> in rpartScore', and the latent variable ordinal forests of Hornung (2020) <doi:10.1007/s00357-018-9302-x> in ordinalForest'.

This package provides a client that grants access to the power of the ohsome API from R. It lets you analyze the rich data source of the OpenStreetMap (OSM) history. You can retrieve the geometry of OSM data at specific points in time, and you can get aggregated statistics on the evolution of OSM elements and specify your own temporal, spatial and/or thematic filters.

Interface to OpenStreetMap API for fetching and saving data from/to the OpenStreetMap database (<https://wiki.openstreetmap.org/wiki/API_v0.6>).

The online principal component method can process the online data set. The philosophy of the package is described in Guo G. (2018) <doi:10.1080/10485252.2018.1531130>.