This package implements a wide range of metrics for measuring glucose control and glucose variability based on continuous glucose monitoring data. The list of implemented metrics is summarized in Rodbard (2009) <doi:10.1089/dia.2009.0015>. Additional visualization tools include time-series plots, lasagna plots and ambulatory glucose profile report.

This package provides functions to clean and process international trade data into an international trade network (ITN) are provided. It then provides a set a functions to undertake analysis and plots of the ITN (extract the backbone, centrality, blockmodels, clustering). Examining the key players in the ITN and regional trade patterns.

Machine learning, containing several algorithms for supervised and unsupervised classification, in addition to a function that plots the Receiver Operating Characteristic (ROC) and Precision-Recall (PRC) curve graphs, and also a function that returns several metrics used for model evaluation, the latter can be used in ranking results from other packs.

Includes functions for conducting univariate and multivariate meta-analysis. This includes the estimation of the asymptotic variance-covariance matrix of effect sizes. For more details see Becker (1992) <doi:10.2307/1165128>, Cooper, Hedges, and Valentine (2019) <doi:10.7758/9781610448864>, and Schmid, Stijnen, and White (2020) <doi:10.1201/9781315119403>.

Simultaneous multiple outcomes prediction based on revised stacking algorithms, which enables the integration of information from predictions of individual models. An implementation of methodologies proposed in our paper: Li Xing, Mary L Lesperance, Xuekui Zhang. (2019) Bioinformatics, "Simultaneous prediction of multiple outcomes using revised stacking algorithms" <doi:10.1093/bioinformatics/btz531>.

Make statistical inference on the probability of being in response, the duration of response, and the cumulative response rate up to a given time point. The method can be applied to analyze phase II randomized clinical trials with the endpoints being time to treatment response and time to progression or death.

Key-value store, implemented as a wrapper around LMDB'; the "lightning memory-mapped database" <https://www.symas.com/mdb>. LMDB is a transactional key value store that uses a memory map for efficient access. This package wraps the entire LMDB interface (except duplicated keys), and provides objects for transactions and cursors.

This comprehensive toolkit for T-distributed regression is designated as "TLIC" (The LIC for T Distribution Regression Analysis) analysis. It is predicated on the assumption that the error term adheres to a T-distribution. The philosophy of the package is described in Guo G. (2020) <doi:10.1080/02664763.2022.2053949>.

Implementation of integrative weighting approaches for multiple observational studies and causal inferences. The package features three weighting approaches, each representing a special case of the unified weighting framework, introduced by Guha and Li (2024) <doi:10.1093/biomtc/ujae070>, which includes an extension of inverse probability weights for data integration settings.

This package provides a novel clustering algorithm and toolkit RCSL (Rank Constrained Similarity Learning) to accurately identify various cell types using scRNA-seq data from a complex tissue. RCSL considers both lo-cal similarity and global similarity among the cells to discern the subtle differences among cells of the same type as well as larger differences among cells of different types. RCSL uses Spearman’s rank correlations of a cell’s expression vector with those of other cells to measure its global similar-ity, and adaptively learns neighbour representation of a cell as its local similarity. The overall similar-ity of a cell to other cells is a linear combination of its global similarity and local similarity.

Interface for multiple data sources, such as the `EDDS` API <https://evds2.tcmb.gov.tr/index.php?/evds/userDocs> of the Central Bank of the Republic of Türkiye and the `FRED` API <https://fred.stlouisfed.org/docs/api/fred/> of the Federal Reserve Bank. Both data providers require API keys for access, which users can easily obtain by creating accounts on their respective websites. The package provides caching ability with the selection of periods to increase the speed and efficiency of requests. It combines datasets requested from different sources, helping users when the data has common frequencies. While combining data frames whenever possible, it also keeps all requested data available as separate data frames to increase efficiency.

This package provides a fast dimensionality reduction method scalable to large numbers of samples. Landmark Multi-Dimensional Scaling (LMDS) is an extension of classical Torgerson MDS, but rather than calculating a complete distance matrix between all pairs of samples, only the distances between a set of landmarks and the samples are calculated.

This package provides tools to perform model selection alongside estimation under Linear, Logistic, Negative binomial, Quantile, and Skew-Normal regression. Under the spike-and-slab method, a probability for each possible model is estimated with the posterior mean, credibility interval, and standard deviation of coefficients and parameters under the most probable model.

An implementation of a variety of escalation with overdose control designs introduced by Babb, Rogatko and Zacks (1998) <doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>. It calculates the next dose as a clinical trial proceeds and performs simulations to obtain operating characteristics.

Lints are code patterns that are not optimal because they are inefficient, forget corner cases, or are less readable. flir provides a small set of functions to detect those lints and automatically fix them. It builds on astgrepr', which itself uses the Rust crate ast-grep to parse and navigate R code.

This package contains the core functions associated with Fast Regularized Canonical Correlation Analysis. Please see the following for details: Raul Cruz-Cano, Mei-Ling Ting Lee, Fast regularized canonical correlation analysis, Computational Statistics & Data Analysis, Volume 70, 2014, Pages 88-100, ISSN 0167-9473 <doi:10.1016/j.csda.2013.09.020>.

Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Hou L, Liu L, HIMA: An R Package for High-Dimensional Mediation Analysis. Journal of Data Science. (2025). <doi:10.6339/25-JDS1192>.

Focuses on data processing and visualization in hydrology and climate forecasting. Main function includes data extraction, data downscaling, data resampling, gap filler of precipitation, bias correction of forecasting data, flexible time series plot, and spatial map generation. It is a good pre- processing and post-processing tool for hydrological and hydraulic modellers.

Wrapper for Stan that offers a number of in-built models to implement a hierarchical Bayesian longitudinal model for repeat observation data. Model choice selects the differential equation that is fit to the observations. Single and multi-individual models are available. O'Brien et al. (2024) <doi:10.1111/2041-210X.14463>.

This package implements approaches of non-parametric smooth test to compare simultaneously K(K>1) copulas and non-parametric clustering of multivariate populations with arbitrary sizes. See Yves I. Ngounou Bakam and Denys Pommeret (2022) <arXiv:2112.05623> and Yves I. Ngounou Bakam and Denys Pommeret (2022) <arXiv:2211.06338>.

This package provides mailmerge methods for reading spreadsheets of addresses and other relevant information to create standardized but customizable letters. Provides a method for mapping US ZIP codes, including those of letter recipients. Provides a method for parsing and processing html code from online job postings of the American Political Science Association.

Uses a kernel smoothing approach to calculate Mutual Information for comparisons between all types of variables including continuous vs continuous, continuous vs discrete and discrete vs discrete. Uses a nonparametric bias correction giving Bias Corrected Mutual Information (BCMI). Implemented efficiently in Fortran 95 with OpenMP and suited to large genomic datasets.

This package provides a complete toolkit to process the Munich ChronoType Questionnaire (MCTQ) for its three versions (standard, micro, and shift). MCTQ is a quantitative and validated tool to assess chronotypes using peoples sleep behavior, originally presented by Till Roenneberg, Anna Wirz-Justice, and Martha Merrow (2003, <doi:10.1177/0748730402239679>).

An implementation of Multi-Task Logistic Regression (MTLR) for R. This package is based on the method proposed by Yu et al. (2011) which utilized MTLR for generating individual survival curves by learning feature weights which vary across time. This model was further extended to account for left and interval censored data.