This package provides data access to counts matrices and meta-data for single-cell RNA sequencing data of thymic epithlial cells across mouse ageing using SMARTseq2 and 10X Genommics chemistries. Access is provided as a data package via ExperimentHub. It is designed to facilitate the re-use of data from Baran-Gale _et al._ in a consistent format that includes relevant and informative meta-data.
This package creates visualization plots for 2D data including ellipse plots, Voronoi tesselation plots, and combined ellipse-Voronoi plots. Designed to visualize class separation in 2D data, raw of from projection techniques like principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA) or others. For more details see Lotsch and Kringel (2026) and Lotsch and Ultsch (2024) <doi:10.1016/j.imu.2024.101573>.
Jade Lizard and Reverse Jade Lizard Option Strategies are presented here through their Graphs. The graphic indicators, strategies, calculations, functions and all the discussions are for academic, research, and educational purposes only and should not be construed as investment advice and come with absolutely no Liability. Russell A. Stultz (â The option strategy desk reference: an essential reference for option traders (First edition.)â , 2019, ISBN: 9781949443912).
This package provides variable selection for linear models and generalized linear models using Bayesian information criterion (BIC) and model posterior probability (MPP). Given a set of candidate predictors, it evaluates candidate models and returns model-level summaries (BIC and MPP) and predictor-level posterior inclusion probabilities (PIP). For more details see Xu, S., Ferreira, M. A., & Tegge, A. N. (2025) <doi:10.48550/arXiv.2510.02628>.
This package provides functions to plot and help understand positive and negative predictive values (PPV and NPV), and their relationship with sensitivity, specificity, and prevalence. See Akobeng, A.K. (2007) <doi:10.1111/j.1651-2227.2006.00180.x> for a theoretical overview of the technical concepts and Navarrete et al. (2015) for a practical explanation about the importance of their understanding <doi:10.3389/fpsyg.2015.01327>.
This package provides a collection of functions for statistical and multivariate analysis of surface-related data, with a focus on antimicrobial activity and omniphobicity. Designed to support materials scientists and researchers in exploring structureâ function relationships in surface-engineered materials through reproducible and interpretable workflows. For more details, see Li et al. (2021) <doi:10.1002/advs.202100368>, and Kwon et al. (2020) <doi:10.3390/polym12081826>.
This module implements the Rijndael cipher which has been selected as the Advanced Encryption Standard. The keysize for Rijndael is 32 bytes. The blocksize is 16 bytes (128 bits). The supported encryption modes are:
MODE_CBC---Cipher Block ChainingMODE_CFB---Cipher feedbackMODE_CTR---Counter modeMODE_ECB---Electronic cookbook modeMODE_OFB---Output feedback
Process results generated by Antares', a powerful open source software developed by RTE (Réseau de Transport dâ à lectricité) to simulate and study electric power systems (more information about Antares here: <https://github.com/AntaresSimulatorTeam/Antares_Simulator>). This package provides functions to create new columns like net load, load factors, upward and downward margins or to compute aggregated statistics like economic surpluses of consumers, producers and sectors.
Spectral emission data for some frequently used lamps including bulbs and flashlights based on led emitting diodes (LEDs) but excluding LEDs available as electronic components. Original spectral irradiance data for incandescent-, LED- and discharge lamps are included. They are complemented by data on the effect of temperature on the emission by fluorescent tubes. Part of the r4photobiology suite, Aphalo P. J. (2015) <doi:10.19232/uv4pb.2015.1.14>.
This package provides functions that compute the spatial covariance matrix for the matern and power classes of spatial models, for data that arise on rectangular units. This code can also be used for the change of support problem and for spatial data that arise on irregularly shaped regions like counties or zipcodes by laying a fine grid of rectangles and aggregating the integrals in a form of Riemann integration.
The clusterGeneration package provides functions for generating random clusters, generating random covariance/correlation matrices, calculating a separation index (data and population version) for pairs of clusters or cluster distributions, and 1-D and 2-D projection plots to visualize clusters. The package also contains a function to generate random clusters based on factorial designs with factors such as degree of separation, number of clusters, number of variables, number of noisy variables.
This is an external ExperimentData package for LRcell. This data package contains the gene enrichment scores calculated from scRNA-seq dataset which indicates the gene enrichment of each cell type in certain brain region. LRcell package is used to identify specific sub-cell types that drives the changes observed in a bulk RNA-seq differential gene expression experiment. For more details, please visit: https://github.com/marvinquiet/LRcell.
Compendium of the most representative algorithms in print---vector-valued dynamic programming, linear programming, policy iteration, the weighting factor approach---for solving multi-objective Markov decision processes, with or without reward discount, over a finite or infinite horizon. Mifrani, A. (2024) <doi:10.1007/s10479-024-06439-x>; Mifrani, A. & Noll, D. <doi:10.48550/arXiv.2502.13697>; Wakuta, K. (1995) <doi:10.1016/0304-4149(94)00064-Z>.
The expander functions rely on the mathematics developed for the Hessian-definiteness invariance theorem for linear projection transformations of variables, described in authors paper, to generate the full, high-dimensional gradient and Hessian from the lower-dimensional derivative objects. This greatly relieves the computational burden of generating the regression-function derivatives, which in turn can be fed into any optimization routine that utilizes such derivatives. The theorem guarantees that Hessian definiteness is preserved, meaning that reasoning about this property can be performed in the low-dimensional space of the base distribution. This is often a much easier task than its equivalent in the full, high-dimensional space. Definiteness of Hessian can be useful in selecting optimization/sampling algorithms such as Newton-Raphson optimization or its sampling equivalent, the Stochastic Newton Sampler. Finally, in addition to being a computational tool, the regression expansion framework is of conceptual value by offering new opportunities to generate novel regression problems.
Mass spectrometry (MS) data backend supporting import and export of MS/MS library spectra from MassBank record files. Different backends are available that allow handling of data in plain MassBank text file format or allow also to interact directly with MassBank SQL databases. Objects from this package are supposed to be used with the Spectra Bioconductor package. This package thus adds MassBank support to the Spectra package.
This package implements specialized K-Nearest Neighbor (KNN) logic to address the unique challenges of spatial modeling in archipelagic environments. Standard contiguity models often leave significant portions of island nations (e.g., 20% of the Philippines) mathematically isolated. This package provides tools to ensure 100% network connectivity, neutralizing spatial bias and enabling robust econometric inference. Methodology follows Anselin (1988, ISBN:9024737354) and LeSage and Pace (2009) <doi:10.1201/9781420064254>.
This RStudio addin makes the creation of Shiny and ShinyDashboard apps more efficient. Besides the necessary folder structure, entire apps can be created using a drag and drop interface and customized with respect to a specific use case. The addin allows the export of the required user interface and server code at any time. By allowing the creation of modules, the addin can be used throughout the entire app development process.
This package provides composable optimization strategies for maximum likelihood estimation (MLE). Solvers are first-class functions that combine via sequential chaining, parallel racing, and random restarts. Implements gradient ascent, Newton-Raphson, quasi-Newton (BFGS), and derivative-free methods with support for constrained optimization and tracing. Returns mle objects compatible with algebraic.mle for downstream analysis. Methods based on Nocedal J, Wright SJ (2006) "Numerical Optimization" <doi:10.1007/978-0-387-40065-5>.
R package for transcriptional analysis based on transcriptograms, a method to analyze transcriptomes that projects expression values on a set of ordered proteins, arranged such that the probability that gene products participate in the same metabolic pathway exponentially decreases with the increase of the distance between two proteins of the ordering. Transcriptograms are, hence, genome wide gene expression profiles that provide a global view for the cellular metabolism, while indicating gene sets whose expressions are altered.
This package implements the Block-wise Rank in Similarity Graph Edge-count test (BRISE), a rank-based two-sample test designed for block-wise missing data. The method constructs (pattern) pair-wise similarity graphs and derives quadratic test statistics with asymptotic chi-square distribution or permutation-based p-values. It provides both vectorized and congregated versions for flexible inference. The methodology is described in Zhang, Liang, Maile, and Zhou (2025) <doi:10.48550/arXiv.2508.17411>.
Imports conversation transcripts into R, concatenates them into a single dataframe appending event identifiers, cleans and formats the text, then yokes user-specified psycholinguistic database values to each word. ConversationAlign then computes alignment indices between two interlocutors across each transcript for >40 possible semantic, lexical, and affective dimensions. In addition to alignment, ConversationAlign also produces a table of analytics (e.g., token count, type-token-ratio) in a summary table describing your particular text corpus.
Implementation of the Future API <doi:10.32614/RJ-2021-048> on top of the batchtools package. This allows you to process futures, as defined by the future package, in parallel out of the box, not only on your local machine or ad-hoc cluster of machines, but also via high-performance compute ('HPC') job schedulers such as LSF', OpenLava', Slurm', SGE', and TORQUE / PBS', e.g. y <- future.apply::future_lapply(files, FUN = process)'.
Inference of ligand-receptor (L-R) interactions from single-cell expression (transcriptomics/proteomics) data. SingleCellSignalR v2 inferences rely on the statistical model we introduced in the BulkSignalR package as well as the original SingleCellSignalR LR-score (both are available). SingleCellSignalR v2 can be regarded as a wrapper to BulkSignalR fundamental classes. This also enables v2 users to work with any species, whereas only Mus musculus & Homo sapiens were available before in SingleCellSignalR v1.
Testing for trajectory presence and heterogeneity on multivariate data. Two statistical methods (Tenha & Song 2022) <doi:10.1371/journal.pcbi.1009829> are implemented. The tree dimension test quantifies the statistical evidence for trajectory presence. The subset specificity measure summarizes pattern heterogeneity using the minimum subtree cover. There is no user tunable parameters for either method. Examples are included to illustrate how to use the methods on single-cell data for studying gene and pathway expression dynamics and pathway expression specificity.