This package provides functions to implement the parametric and non-parametric bootstrap confidence interval methods described in Morrison and Simon (2017) <arXiv:1702.06986>.

This package performs robust estimation and inference when using covariate adjustment and/or covariate-adaptive randomization in randomized controlled trials. This package is trimmed to reduce the dependencies and validated to be used across industry. See "FDA's final guidance on covariate adjustment"<https://www.regulations.gov/docket/FDA-2019-D-0934>, Tsiatis (2008) <doi:10.1002/sim.3113>, Bugni et al. (2018) <doi:10.1080/01621459.2017.1375934>, Ye, Shao, Yi, and Zhao (2023)<doi:10.1080/01621459.2022.2049278>, Ye, Shao, and Yi (2022)<doi:10.1093/biomet/asab015>, Rosenblum and van der Laan (2010)<doi:10.2202/1557-4679.1138>, Wang et al. (2021)<doi:10.1080/01621459.2021.1981338>, Ye, Bannick, Yi, and Shao (2023)<doi:10.1080/24754269.2023.2205802>, and Bannick, Shao, Liu, Du, Yi, and Ye (2024)<doi:10.48550/arXiv.2306.10213>.

It is devoted to the IVIVC linear level A with numerical deconvolution method. The latter is working for inequal and incompatible timepoints between impulse and response curves. A numerical convolution method is also available. Application domains include pharamaceutical industry QA/QC and R&D together with academic research.

Superclasses PostgreSQL connection to help enable full dplyr functionality on Redshift'.

Radiomics image analysis toolbox for 2D and 3D radiological images. RIA supports DICOM, NIfTI, nrrd and npy (numpy array) file formats. RIA calculates first-order, gray level co-occurrence matrix, gray level run length matrix and geometry-based statistics. Almost all calculations are done using vectorized formulas to optimize run speeds. Calculation of several thousands of parameters only takes minutes on a single core of a conventional PC. Detailed methodology has been published: Kolossvary et al. Circ: Cardiovascular Imaging. 2017;10(12):e006843 <doi: 10.1161/CIRCIMAGING.117.006843>.

Processes and visualizes the output of complex phylogenetic analyses from the RevBayes phylogenetic graphical modeling software.

Access Synthesize Bio models from their API <https://app.synthesize.bio/> using this wrapper that provides a convenient interface to the Synthesize Bio API, allowing users to generate realistic gene expression data based on specified biological conditions. This package enables researchers to easily access AI-generated transcriptomic data for various modalities including bulk RNA-seq, single-cell RNA-seq, microarray data, and more.

An implementation of the Heroicons icon library for shiny applications and other R web-based projects. You can search, render, and customize icons without CSS or JavaScript dependencies.

Build regular expressions piece by piece using human readable code. This package contains number-related functionality, and is primarily intended to be used by package developers.

Providing wrapper functions to implement Bayesian analysis in JAGS. Some major features include monitoring convergence of a MCMC model using Rubin and Gelman Rhat statistics, automatically running a MCMC model till it converges, and implementing parallel processing of a MCMC model for multiple chains.

An implementation of the WOFOST ("World Food Studies") crop growth model. WOFOST is a dynamic simulation model that uses daily weather data, and crop, soil and management parameters to simulate crop growth and development. See De Wit et al. (2019) <doi:10.1016/j.agsy.2018.06.018> for a recent review of the history and use of the model.

Data sets are often corrupted by outliers. When data are multivariate outliers can be classified as case-wise or cell-wise. The latters are particularly challenge to handle. We implement a robust estimation procedure for Seemingly Unrelated Regression Models which is able to cope well with both type of outliers. Giovanni Saraceno, Fatemah Alqallaf, Claudio Agostinelli (2021) <doi:10.48550/arXiv.2107.00975>.

Import SGF (Smart Game File) into R.

Maximum likelihood estimation for univariate reducible stochastic differential equation models. Discrete, possibly noisy observations, not necessarily evenly spaced in time. Can fit multiple individuals/units with global and local parameters, by fixed-effects or mixed-effects methods. Ref.: Garcia, O. (2019) "Estimating reducible stochastic differential equations by conversion to a least-squares problem", Computational Statistics 34(1): 23-46, <doi:10.1007/s00180-018-0837-4>.

Toolbox with shiny applications for widely used psychometric methods. Those methods include following analysis: Item analysis, item response theory calibration, principal component analysis, confirmatory factor analysis - structural equation modeling, generating simulated data. References: Chalmers (2012, <doi:10.18637/jss.v048.i06>); Revelle (2022, <https://CRAN.R-project.org/package=psych Version = 2.2.9.>); Rosseel (2012, <doi:10.18637/jss.v048.i02>); Magis & Raiche (2012, <doi:10.18637/jss.v048.i08>); Magis & Barrada (2017, <doi:10.18637/jss.v076.c01>).

Random vectors, called rvecs. An rvec holds multiple draws, but tries to behave like a standard R vector, including working well in data frames. Rvecs are useful for analysing output from a simulation or a Bayesian analysis.

Numerous functions for cohort-based analyses, either for prediction or causal inference. For causal inference, it includes Inverse Probability Weighting and G-computation for marginal estimation of an exposure effect when confounders are expected. We deal with binary outcomes, times-to-events, competing events, and multi-state data. For multistate data, semi-Markov model with interval censoring may be considered, and we propose the possibility to consider the excess of mortality related to the disease compared to reference lifetime tables. For predictive studies, we propose a set of functions to estimate time-dependent receiver operating characteristic (ROC) curves with the possible consideration of right-censoring times-to-events or the presence of confounders. Finally, several functions are available to assess time-dependent ROC curves or survival curves from aggregated data.

R-level and C++-level functionality to generate random deviates from and calculate moments of a Truncated Normal distribution using the algorithm of Robert (1995) <DOI:10.1007/BF00143942>. In addition to RNG, functions for calculating moments, densities, and entropies are provided at both levels.

Mixed Treatment Comparison is a methodology to compare directly and/or indirectly health strategies (drugs, treatments, devices). This package provides an Rcmdr plugin to perform Mixed Treatment Comparison for binary outcome using BUGS code from Bristol University (Lu and Ades).

Enhances the R Optimization Infrastructure ('ROI') package with the quadratic solver HiGHS'. More information about HiGHS can be found at <https://highs.dev>.

The cnpy library written by Carl Rogers provides read and write facilities for files created with (or for) the NumPy extension for Python'. Vectors and matrices of numeric types can be read or written to and from files as well as compressed files. Support for integer files is available if the package has been built with as C++11 which should be the default on all platforms since the release of R 3.3.0.

Companion package for the book: "Robust Statistics: Theory and Methods, second edition", <http://www.wiley.com/go/maronna/robust>. This package contains code that implements the robust estimators discussed in the recent second edition of the book above, as well as the scripts reproducing all the examples in the book.

This package provides a small language extension for succinct conditional assignment using `?` and `:`, emulating the conditional ternary operator syntax using in C, Java, JavaScript and other languages.

The parametric Bayes analysis for the restricted mean survival time (RMST) with cluster effect, as described in Hanada and Kojima (2024) <doi:10.48550/arXiv.2406.06071>. Bayes estimation with random-effect and frailty-effect can be applied to several parametric models useful in survival time analysis. The RMST under these parametric models can be computed from the obtained posterior samples.