This package is an implementation of about 6 major classes of statistical regression models. Currently only fixed-effects models are implemented, i.e., no random-effects models. Many (150+) models and distributions are estimated by maximum likelihood estimation (MLE) or penalized MLE, using Fisher scoring. VGLMs can be loosely thought of as multivariate generalised linear models.

In order to make Arrow Database Connectivity ('ADBC <https://arrow.apache.org/adbc/>) accessible from R, an interface compliant with the DBI package is provided, using driver back-ends that are implemented in the adbcdrivermanager framework. This enables interacting with database systems using the Arrow data format, thereby offering an efficient alternative to ODBC for analytical applications.

The main function generateDataset() processes a user-supplied .R file that contains metadata parameters in order to generate actual data. The metadata parameters have to be structured in the form of metadata objects, the format of which is outlined in the package vignette. This approach allows to generate artificial data in a transparent and reproducible manner.

This package provides a method to filter correlation and covariance matrices by averaging bootstrapped filtered hierarchical clustering and boosting. See Ch. Bongiorno and D. Challet, Covariance matrix filtering with bootstrapped hierarchies (2020) <arXiv:2003.05807> and Ch. Bongiorno and D. Challet, Reactive Global Minimum Variance Portfolios with k-BAHC covariance cleaning (2020) <arXiv:2005.08703>.

An implementation of extended state-space SIR models developed by Song Lab at UM school of Public Health. There are several functions available by 1) including a time-varying transmission modifier, 2) adding a time-dependent quarantine compartment, 3) adding a time-dependent antibody-immunization compartment. Wang L. (2020) <doi:10.6339/JDS.202007_18(3).0003>.

Because fungicide resistance is an important phenotypic trait for fungi and oomycetes, it is necessary to have a standardized method of statistically analyzing the Effective Concentration (EC) values. This package is designed for those who are not terribly familiar with R to be able to analyze and plot an entire set of isolates using the drc package.

Unsupervised, multivariate, binary clustering for meaningful annotation of data, taking into account the uncertainty in the data. A specific constructor for trajectory analysis in movement ecology yields behavioural annotation of trajectories based on estimated local measures of velocity and turning angle, eventually with solar position covariate as a daytime indicator, ("Expectation-Maximization Binary Clustering for Behavioural Annotation").

Automated compound deconvolution, alignment across samples, and identification of metabolites by spectral library matching in Gas Chromatography - Mass spectrometry (GC-MS) untargeted metabolomics. Outputs a table with compound names, matching scores and the integrated area of the compound for each sample. Package implementation is described in Domingo-Almenara et al. (2016) <doi:10.1021/acs.analchem.6b02927>.

This package implements genetic algorithm and particle swarm algorithm for real-valued functions. Various modifications (including hybridization and elitism) of these algorithms are provided. Implemented functions are based on ideas described in S. Katoch, S. Chauhan, V. Kumar (2020) <doi:10.1007/s11042-020-10139-6> and M. Clerc (2012) <https://hal.archives-ouvertes.fr/hal-00764996>.

We present this package for fitting structural equation models using the hierarchical likelihood method. This package allows extended structural equation model, including dynamic structural equation model. We illustrate the use of our packages with well-known data sets. Therefore, this package are able to handle two serious problems inadmissible solution and factor indeterminacy <doi:10.3390/sym13040657>.

Efficient implementations of the following multiple changepoint detection algorithms: Efficient Sparsity Adaptive Change-point estimator by Moen, Glad and Tveten (2023) <doi:10.48550/arXiv.2306.04702> , Informative Sparse Projection for Estimating Changepoints by Wang and Samworth (2017) <doi:10.1111/rssb.12243>, and the method of Pilliat et al (2023) <doi:10.1214/23-EJS2126>.

An implementation of the Invariance Partial Pruning (IVPP) approach described in Du, X., Johnson, S. U., Epskamp, S. (2025) The Invariance Partial Pruning Approach to The Network Comparison in Longitudinal Data. IVPP is a two-step method that first test for global network structural difference with invariance test and then inspect specific edge difference with partial pruning.

Empirical Bayes variable selection via ICM/M algorithm for normal, binary logistic, and Cox's regression. The basic problem is to fit high-dimensional regression which sparse coefficients. This package allows incorporating the Ising prior to capture structure of predictors in the modeling process. More information can be found in the papers listed in the URL below.

Bayesian methods for estimating developmental age from ordinal dental data. For an explanation of the model used, see Konigsberg (2015) <doi:10.3109/03014460.2015.1045430>. For details on the conditional correlation correction, see Sgheiza (2022) <doi:10.1016/j.forsciint.2021.111135>. Dental scoring is based on Moorrees, Fanning, and Hunt (1963) <doi:10.1177/00220345630420062701>.

Estimation of extended joint models with shared random effects. Longitudinal data are handled in latent process models for continuous (Gaussian or curvilinear) and ordinal outcomes while proportional hazard models are used for the survival part. We propose a frequentist approach using maximum likelihood estimation. See Saulnier et al, 2022 <doi:10.1016/j.ymeth.2022.03.003>.

The programs were developed for estimation of parameters and testing exponential versus Pareto distribution during our work on hydrologic extremes. See Kozubowski, T.J., A.K. Panorska, F. Qeadan, and A. Gershunov (2007) <doi:10.1080/03610910802439121>, and Panorska, A.K., A. Gershunov, and T.J. Kozubowski (2007) <doi:10.1007/978-0-387-34918-3_26>.

Generate pseudonymous animal names that are delightful and easy to remember like the Likable Leech and the Proud Chickadee. A unique pseudonym can be created for every unique element in a vector or row in a data frame. Pseudonyms can be customized and tracked over time, so that the same input is always assigned the same pseudonym.

Calculates the number of true positives and false positives from a dataset formatted for Jackknife alternative free-response receiver operating characteristic which is used for statistical analysis which is explained in the book Chakraborty DP (2017), "Observer Performance Methods for Diagnostic Imaging - Foundations, Modeling, and Applications with R-Based Examples", Taylor-Francis <https://www.crcpress.com/9781482214840>.

An implementation of the time-series Susceptible-Infected-Recovered (TSIR) model using a number of different fitting options for infectious disease time series data. The manuscript based on this package can be found here <doi:10.1371/journal.pone.0185528>. The method implemented here is described by Finkenstadt and Grenfell (2000) <doi:10.1111/1467-9876.00187>.

BEER implements a Bayesian model for analyzing phage-immunoprecipitation sequencing (PhIP-seq) data. Given a PhIPData object, BEER returns posterior probabilities of enriched antibody responses, point estimates for the relative fold-change in comparison to negative control samples, and more. Additionally, BEER provides a convenient implementation for using edgeR to identify enriched antibody responses.

This package contains the function to assess the batch sourcs by fitting all "sources" as random effects including two-way interaction terms in the Mixed Model(depends on lme4 package) to selected principal components, which were obtained from the original data correlation matrix. This package accompanies the book "Batch Effects and Noise in Microarray Experiements, chapter 12.

Expedite large RNA-Seq analyses using a combination of previously developed tools. YARN is meant to make it easier for the user in performing basic mis-annotation quality control, filtering, and condition-aware normalization. YARN leverages many Bioconductor tools and statistical techniques to account for the large heterogeneity and sparsity found in very large RNA-seq experiments.

Genomic data analyses requires integrated visualization of known genomic information and new experimental data. Gviz uses the biomaRt and the rtracklayer packages to perform live annotation queries to Ensembl and UCSC and translates this to e.g. gene/transcript structures in viewports of the grid graphics package. This results in genomic information plotted together with your data.

Calculates the Boltzmann entropy of a landscape gradient. This package uses the analytical method created by Gao, P., Zhang, H. and Li, Z., 2018 (<doi:10.1111/tgis.12315>) and by Gao, P. and Li, Z., 2019 (<doi:10.1007/s10980-019-00854-3>). It also extend the original ideas by allowing calculations on data with missing values.