Apply the spectral residual algorithm to data, such as a time series, to detect anomalies. Anomaly scores can be used to determine outliers based upon a threshold or fed into more sophisticated prediction models. Methods are based upon "Time-Series Anomaly Detection Service at Microsoft", Ren, H., Xu, B., Wang, Y., et al., (2019) <doi:10.48550/arXiv.1906.03821>.

EZR (Easy R) adds a variety of statistical functions, including survival analyses, ROC analyses, metaanalyses, sample size calculation, and so on, to the R commander. EZR enables point-and-click easy access to statistical functions, especially for medical statistics. EZR is platform-independent and runs on Windows, Mac OS X, and UNIX. Its complete manual is available only in Japanese (Chugai Igakusha, ISBN: 978-4-498-10918-6, Nankodo, ISBN: 978-4-524-21861-5, Ohmsha, ISBN: 978-4-274-22632-8), but an report that introduced the investigation of EZR was published in Bone Marrow Transplantation (Nature Publishing Group) as an Open article. This report can be used as a simple manual. It can be freely downloaded from the journal website as shown below. This report has been cited in more than 14,000 scientific articles.

systemPipeRdata complements the systemPipeR workflow management system (WMS) by offering a collection of pre-designed data analysis workflow templates. These templates are easily accessible and can be readily loaded onto a user's system with a single command. Once loaded, the WMS can immediately utilize these templates for efficient end-to-end analysis, serving a wide range of data analysis needs.

Multivariate random forests with compositional responses and Euclidean predictors is performed. The compositional data are first transformed using the additive log-ratio transformation, or the alpha-transformation of Tsagris, Preston and Wood (2011), <doi:10.48550/arXiv.1106.1451>, and then the multivariate random forest of Rahman R., Otridge J. and Pal R. (2017), <doi:10.1093/bioinformatics/btw765>, is applied.

Package takes frequencies of mutations as reported by high throughput sequencing data from cancer and fits a theoretical neutral model of tumour evolution. Package outputs summary statistics and contains code for plotting the data and model fits. See Williams et al 2016 <doi:10.1038/ng.3489> and Williams et al 2017 <doi:10.1101/096305> for further details of the method.

Analysis and measurement of promotion effectiveness on a given target variable (e.g. daily sales). After converting promotion schedule into dummy or smoothed predictor variables, the package estimates the effects of these variables controlled for trend/periodicity/structural change using prophet by Taylor and Letham (2017) <doi:10.7287/peerj.preprints.3190v2> and some prespecified variables (e.g. start of a month).

This package provides a set of Study Data Tabulation Model (SDTM) datasets from the Clinical Data Interchange Standards Consortium (CDISC) pilot project used for testing and developing Analysis Data Model (ADaM) datasets inside the pharmaverse family of packages. SDTM dataset specifications are described in the CDISC SDTM implementation guide, accessible by creating a free account on <https://www.cdisc.org/>.

An implementation of reliability estimation methods described in the paper (Bosnic, Z., & Kononenko, I. (2008) <doi:10.1007/s10489-007-0084-9>), which allows you to test the reliability of a single predicted instance made by your model and prediction function. It also allows you to make a correlation test to estimate which reliability estimate is the most accurate for your model.

Enriched heatmap is a special type of heatmap which visualizes the enrichment of genomic signals on specific target regions. This type of heatmap is just a normal heatmap but with some special settings, with the functionality of ComplexHeatmap, it would be much easier to customize the heatmap as well as concatenating to a list of heatmaps to show correspondence between different data sources.

Spatial and non-spatial regression models with compositional responses (and compositional predictors) using the alpha--transformation. Relevant papers include: Tsagris M. and Pantazis Y. (2026), <doi:10.48550/arXiv.2510.12663>, Tsagris M. (2015), <https://soche.cl/chjs/volumes/06/02/Tsagris(2015).pdf>, Tsagris M.T., Preston S. and Wood A.T.A. (2011), <doi:10.48550/arXiv.1106.1451>.

This package contains functions which can be used to calculate Pesticide Risk Metric values in aquatic environments from concentrations of multiple pesticides with known species sensitive distributions (SSDs). Pesticides provided by this package have all be validated however if the user has their own pesticides with SSD values they can append them to the pesticide_info table to include them in estimates.

This package provides a set of Analysis Data Model (ADaM) datasets constructed using the Study Data Tabulation Model (SDTM) datasets contained in the pharmaversesdtm package and the template scripts from the admiral family of packages. ADaM dataset specifications are described in the CDISC ADaM implementation guide, accessible by creating a free account on <https://www.cdisc.org/>.

This package provides measures of effect sizes for summarized continuous variables as well as diagnostic accuracy statistics for 2x2 table data. Includes functions for Cohen's d, robust effect size, Cohen's q, partial eta-squared, coefficient of variation, odds ratio, likelihood ratios, sensitivity, specificity, positive and negative predictive values, Youden index, number needed to treat, number needed to diagnose, and predictive summary index.

Estimates phylogenetic trees from allele count data using the root distance method under the Coalescent Model. Given a matrix of allele counts across taxa and loci, the package estimates pairwise root distances under the Coalescent Model using maximum likelihood estimation. Then, it estimates a labeled phylogenetic tree from the estimated root distances. See Peng et al. (2021) <doi:10.1016/j.ympev.2021.107142>.

Statistical methods for DNA mixture analysis. This package is a lite-version of the DNAmixtures package to allow users without a HUGIN software license to experiment with the statistical methodology. While the lite-version aims to provide the full functionality it is noticeably less efficient than the original DNAmixtures package. For details on implementation and methodology see <https://dnamixtures.r-forge.r-project.org/>.

The basic use of this package is with 3 sequential functions. First to generate a cell mean matrix. In case of a repeated measurements design also generate correlation and covariance matrices. This is followed by iterative experiment simulation. Finally, power is calculated from the simulated data. Features that may be considered in the model are interaction, measure correlation, non-normal and unbalanced designs distributions.

This package provides utilities for manipulating time series of location-based counts of events to detect geo-spatial clusters. Significance of these clusters is determined using a set of models that classify based on a learned relationship between observed and the log(observed/expected) ratio of counts. The approach implemented here is similar to prospective space-time estimation of clusters using the scan statistic.

This package provides the Augmented Dickey-Fuller test and its variations to check the existence of bubbles (explosive behavior) for time series, based on the article by Peter C. B. Phillips, Shuping Shi and Jun Yu (2015a) <doi:10.1111/iere.12131>. Some functions may take a while depending on the size of the data used, or the number of Monte Carlo replications applied.

This package provides functions for assessing variable relations and associations prior to modeling with a Random Forest algorithm (although these are relevant for any predictive model). Metrics such as partial correlations and variance inflation factors are tabulated as well as plotted for the user. A function is available for tuning the main Random Forest hyper-parameter based on model performance and variable importance metrics. This grid-search technique provides tables and plots showing the effect of the main hyper-parameter on each of the assessment metrics. It also returns each of the evaluated models to the user. The package also provides superior variable importance plots for individual models. All of the plots are developed so that the user has the ability to edit and improve further upon the plots. Derivations and methodology are described in Bladen (2022) <https://digitalcommons.usu.edu/etd/8587/>.

This package provides a tool to search and download a collection of publicly available single cell ATAC-seq datasets and their metadata. scATAC-Explorer aims to act as a single point of entry for users looking to study single cell ATAC-seq data. Users can quickly search available datasets using the metadata table and download datasets of interest for immediate analysis within R.

This package implements the high-dimensional changepoint detection method GeomCP and the related mappings used for changepoint detection. These methods view the changepoint problem from a geometrical viewpoint and aim to extract relevant geometrical features in order to detect changepoints. The geomcp() function should be your first point of call. References: Grundy et al. (2020) <doi:10.1007/s11222-020-09940-y>.

This package provides tools to compute directly standardised rates using the 2013 European Standard Population for age and deprivation-standardised rates using a 10% per decile assumption. Sex standardisation uses an assumed equal proportion of both males and females. The package Includes variance estimation and 95% confidence intervals for population health applications. Functions support flexible grouping variables and age bands, enabling reproducible and automated analyses.

Setup and connect to OpenTripPlanner (OTP) <http://www.opentripplanner.org/>. OTP is an open source platform for multi-modal and multi-agency journey planning written in Java'. The package allows you to manage a local version or connect to remote OTP server to find walking, cycling, driving, or transit routes. This package has been peer-reviewed by rOpenSci (v. 0.2.0.0).

Location- and scale-invariant Box-Cox and Yeo-Johnson power transformations allow for transforming variables with distributions distant from 0 to normality. Transformers are implemented as S4 objects. These allow for transforming new instances to normality after optimising fitting parameters on other data. A test for central normality allows for rejecting transformations that fail to produce a suitably normal distribution, independent of sample number.