Uses an indirect method based on truncated quantile-quantile plots to estimate reference limits from routine laboratory data: Georg Hoffmann and colleagues (2024) <doi: 10.3390/jcm13154397>. The principle of the method was developed by Robert G Hoffmann (1963) <doi:10.1001/jama.1963.03060110068020> and modified by Georg Hoffmann and colleagues (2015) <doi:10.1515/labmed-2015-0104>, and Frank Klawonn and colleagues (2020) <doi:10.1515/labmed-2020-0005>, (2022) <doi:10.1007/978-3-031-15509-3_31>.

Interface to easily access data via the United States Department of Agriculture (USDA)'s Agricultural Resource Management Survey (ARMS) Data API <https://www.ers.usda.gov/developer/data-apis/arms-data-api/>. The downloaded data can be saved for later off-line use. Also provide relevant information and metadata for each of the input variables needed for sending the data inquery.

Here we performs robust hierarchical co-clustering between row and column entities of a data matrix in absence and presence of outlying observations. It can be used to explore important co-clusters consisting of important samples and their regulatory significant features. Please see Hasan, Badsha and Mollah (2020) <doi:10.1101/2020.05.13.094946>.

Adaptation of the Matlab tsEVA toolbox developed by Lorenzo Mentaschi available here: <https://github.com/menta78/tsEva>. It contains an implementation of the Transformed-Stationary (TS) methodology for non-stationary extreme value Analysis (EVA) as described in Mentaschi et al. (2016) <doi:10.5194/hess-20-3527-2016>. In synthesis this approach consists in: (i) transforming a non-stationary time series into a stationary one to which the stationary extreme value theory can be applied; and (ii) reverse-transforming the result into a non-stationary extreme value distribution. RtsEva offers several options for trend estimation (mean, extremes, seasonal) and contains multiple plotting functions displaying different aspects of the non-stationarity of extremes.

This package contains utilities for the analysis of Michaelian kinetic data. Beside the classical linearization methods (Lineweaver-Burk, Eadie-Hofstee, Hanes-Woolf and Eisenthal-Cornish-Bowden), features include the ability to carry out weighted regression analysis that, in most cases, substantially improves the estimation of kinetic parameters (Aledo (2021) <doi:10.1002/bmb.21522>). To avoid data transformation and the potential biases introduced by them, the package also offers functions to directly fitting data to the Michaelis-Menten equation, either using ([S], v) or (time, [S]) data. Utilities to simulate substrate progress-curves (making use of the Lambert W function) are also provided. The package is accompanied of vignettes that aim to orientate the user in the choice of the most suitable method to estimate the kinetic parameter of an Michaelian enzyme.

This package provides functions to allow users to build and analyze design consistent tree and random forest models using survey data from a complex sample design. The tree model algorithm can fit a linear model to survey data in each node obtained by recursively partitioning the data. The splitting variables and selected splits are obtained using a randomized permutation test procedure which adjusted for complex sample design features used to obtain the data. Likewise the model fitting algorithm produces design-consistent coefficients to any specified least squares linear model between the dependent and independent variables used in the end nodes. The main functions return the resulting binary tree or random forest as an object of "rpms" or "rpms_forest" type. The package also provides methods modeling a "boosted" tree or forest model and a tree model for zero-inflated data as well as a number of functions and methods available for use with these object types.

This package provides functions to fit Gaussian linear model by maximising the residual log likelihood where the covariance structure can be written as a linear combination of known matrices. Can be used for multivariate models and random effects models. Easy straight forward manner to specify random effects models, including random interactions. Code now optimised to use Sherman Morrison Woodbury identities for matrix inversion in random effects models. We've added the ability to fit models using any kernel as well as a function to return the mean and covariance of random effects conditional on the data (best linear unbiased predictors, BLUPs). Clifford and McCullagh (2006) <https://www.r-project.org/doc/Rnews/Rnews_2006-2.pdf>.

This package provides a simple and efficient way to read data from Paradox database files (.db) directly into R as modern tibble data frames. It uses the underlying pxlib C library, to handle the low-level file format details and provides a clean, user-friendly R interface.

Function for adapting the shape of the random walk Metropolis proposal as specified by robust adaptive Metropolis algorithm by Vihola (2012) <doi:10.1007/s11222-011-9269-5>. The package also includes fast functions for rank-one Cholesky update and downdate. These functions can be used directly from R or the corresponding C++ header files can be easily linked to other R packages.

This package provides a user-friendly interface to NASA Exoplanets Archive API <https://exoplanetarchive.ipac.caltech.edu/>, enabling retrieval and analysis of exoplanetary and stellar data. Includes functions for querying, filtering, summarizing, and computing derived parameters from the Exoplanets catalog.

R bindings for functions from the UCR Suite by Rakthanmanon et al. (2012) <DOI:10.1145/2339530.2339576>, which enables ultrafast subsequence search for a best match under Dynamic Time Warping and Euclidean Distance.

This package provides R bindings for Tabulator JS <https://tabulator.info/>. Makes it a breeze to create highly customizable interactive tables in rmarkdown documents and shiny applications. It includes filtering, grouping, editing, input validation, history recording, column formatters, packaged themes and more.

Perform structural reliability analysis, including computation and simulation with system signatures, Samaniego (2007) <doi:10.1007/978-0-387-71797-5>, and survival signatures, Coolen and Coolen-Maturi (2013) <doi:10.1007/978-3-642-30662-4_8>. Additionally supports parametric and topological inference given system lifetime data, Aslett (2012) <https://www.louisaslett.com/PhD_Thesis.pdf>.

Set of utilities to facilitate the reproduction of analysis in R. It allow to make_structure(), clean_structure(), and run and log programs in a predefined order to allow secondary files, analysis and reports be constructed in an ordered and reproducible form.

Carry out principal component analysis (PCA) of very large pedigrees such as found in breeding populations! This package exploits sparse matrices and randomised linear algebra to deliver a gazillion-times speed-up compared to naive singular value decoposition (SVD) (and eigen decomposition).

Provide estimation and data generation tools for the quantile generalized beta regression model. For details, see Bourguignon, Gallardo and Saulo <arXiv:2110.04428> The package also provides tools to perform covariates selection.

Accurately estimates the reliability of cognitive tasks using a fast and flexible permutation-based split-half reliability algorithm that supports stratified splitting while maintaining equal split sizes. See Kahveci, Bathke, and Blechert (2025) <doi:10.3758/s13423-024-02597-y> for details.

The rema package implements a permutation-based approach for binary meta-analyses of 2x2 tables, founded on conditional logistic regression, that provides more reliable statistical tests when heterogeneity is observed in rare event data (Zabriskie et al. 2021 <doi:10.1002/sim.9142>). To adjust for the effect of heterogeneity, this method conditions on the sufficient statistic of a proxy for the heterogeneity effect as opposed to estimating the heterogeneity variance. While this results in the model not strictly falling under the random-effects framework, it is akin to a random-effects approach in that it assumes differences in variability due to treatment. Further, this method does not rely on large-sample approximations or continuity corrections for rare event data. This method uses the permutational distribution of the test statistic instead of asymptotic approximations for inference. The number of observed events drives the computation complexity for creating this permutational distribution. Accordingly, for this method to be computationally feasible, it should only be applied to meta-analyses with a relatively low number of observed events. To create this permutational distribution, a network algorithm, based on the work of Mehta et al. (1992) <doi:10.2307/1390598> and Corcoran et al. (2001) <doi:10.1111/j.0006-341x.2001.00941.x>, is employed using C++ and integrated into the package.

The goal of rFIA is to increase the accessibility and use of the United States Forest Services (USFS) Forest Inventory and Analysis (FIA) Database by providing a user-friendly, open source toolkit to easily query and analyze FIA Data. Designed to accommodate a wide range of potential user objectives, rFIA simplifies the estimation of forest variables from the FIA Database and allows all R users (experts and newcomers alike) to unlock the flexibility inherent to the Enhanced FIA design. Specifically, rFIA improves accessibility to the spatial-temporal estimation capacity of the FIA Database by producing space-time indexed summaries of forest variables within user-defined population boundaries. Direct integration with other popular R packages (e.g., dplyr', tidyr', and sf') facilitates efficient space-time query and data summary, and supports common data representations and API design. The package implements design-based estimation procedures outlined by Bechtold & Patterson (2005) <doi:10.2737/SRS-GTR-80>, and has been validated against estimates and sampling errors produced by FIA EVALIDator'. Current development is focused on the implementation of spatially-enabled model-assisted and model-based estimators to improve population, change, and ratio estimates.

Implementation of the race/ethnicity prediction method, described in "rethnicity: An R package for predicting ethnicity from names" by Fangzhou Xie (2022) <doi:10.1016/j.softx.2021.100965> and "Rethnicity: Predicting Ethnicity from Names" by Fangzhou Xie (2021) <doi:10.48550/arXiv.2109.09228>.

This package provides the log-likelihoods with gradients from stan (Carpenter et al (2015), <doi:10.48550/arXiv.1509.07164>) needed for generalized log-likelihood estimation in nlmixr2 (Fidler et al (2019) <doi:10.1002/psp4.12445>). This is split of to reduce computational burden of recompiling rxode2 (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) which runs the nlmixr2 models during estimation.

Package to Handle R Requests from R Service Bus Applications with JSON Payloads in a generic way. The incoming request is encoded as a string (character vector of length one) containing the JSON file passed through by the client.

Compiles C++ code using Rcpp <doi:10.18637/jss.v040.i08>, Eigen <doi:10.18637/jss.v052.i05> and CppAD to produce first and second order partial derivatives. Also provides an implementation of Faa di Bruno's formula to combine the partial derivatives of composed functions.

Supports analysis of spatial data processed with the GeoPAT 2 software <https://github.com/Nowosad/geopat2>. Available features include creation of a grid based on the GeoPAT 2 grid header file and reading a GeoPAT 2 text outputs.