Bayesian analysis of censored linear mixed-effects models that replace Gaussian assumptions with a flexible class of distributions, such as the scale mixture of normal family distributions, considering a damped exponential correlation structure which was employed to account for within-subject autocorrelation among irregularly observed measures. For more details, see Kelin Zhong, Fernanda L. Schumacher, Luis M. Castro, Victor H. Lachos (2025) <doi:10.1002/sim.10295>.

Maximum likelihood estimation of the parameters of matrix and 3rd-order tensor normal distributions with unstructured factor variance covariance matrices, two procedures, and for unbiased modified likelihood ratio testing of simple and double separability for variance-covariance structures, two procedures. References: Dutilleul P. (1999) <doi:10.1080/00949659908811970>, Manceur AM, Dutilleul P. (2013) <doi:10.1016/j.cam.2012.09.017>, and Manceur AM, Dutilleul P. (2013) <doi:10.1016/j.spl.2012.10.020>.

Implementation of all possible forms of 2x2 and 3x3 space-filling curves, i.e., the generalized forms of the Hilbert curve <https://en.wikipedia.org/wiki/Hilbert_curve>, the Peano curve <https://en.wikipedia.org/wiki/Peano_curve> and the Peano curve in the meander type (Figure 5 in <https://eudml.org/doc/141086>). It can generates nxn curves expanded from any specific level-1 units. It also implements the H-curve and the three-dimensional Hilbert curve.

This package implements the s-values proposed by Ed. Leamer. It provides a context-minimal approach for sensitivity analysis using extreme bounds to assess the sturdiness of regression coefficients.

Input widget that allows to construct complex filtering queries in Shiny'. It's a wrapper for JavaScript library jQuery-QueryBuilder', check <https://querybuilder.js.org/>.

Add-on for the scan package that creates plots from single-case data frames ('scdf'). It includes functions for styling single-case plots, adding phase-based lines to indicate various statistical parameters, and predefined themes for presentations and publications. More information and in depth examples can be found in the online book "Analyzing Single-Case Data with R and scan" Jürgen Wilbert (2025) <https://jazznbass.github.io/scan-Book/>.

Generate the optimal Latin Hypercube Designs (LHDs) for computer experiments with quantitative factors and the optimal Sliced Latin Hypercube Designs (SLHDs) for computer experiments with both quantitative and qualitative factors. Details of the algorithm can be found in Ba, S., Brenneman, W. A. and Myers, W. R. (2015), "Optimal Sliced Latin Hypercube Designs," Technometrics. Important function in this package is "maximinSLHD".

The number of studies involving correlated traits and the availability of tools to handle this type of data has increased considerably in the last decade. With such a demand, we need tools for testing hypotheses related to single and multi-trait (correlated) phenotypes based on many genetic settings. Thus, we implemented various options for simulation of pleiotropy and Linkage Disequilibrium under additive, dominance and epistatic models. The simulation currently takes a marker data set as an input and then uses it for simulating multiple traits as described in Fernandes and Lipka (2020) <doi:10.1186/s12859-020-03804-y>.

Sudoku designs (Bailey et al., 2008<doi:10.1080/00029890.2008.11920542>) can be used as experimental designs which tackle one extra source of variation than conventional Latin square designs. Although Sudoku designs are similar to Latin square designs, only addition is the region concept. Some very important functions related to row-column designs as well as block designs along with basic functions are included in this package.

This package provides a convenient interface for formatting SQL queries directly within R'. It acts as a wrapper around the sql_format Rust crate. The package allows you to format SQL code with customizable options, including indentation, case formatting, and more, ensuring your SQL queries are clean, readable, and consistent.

Estimation of function and index vector in single index model ('sim') with (and w/o) shape constraints including different smoothness conditions. See, e.g., Kuchibhotla and Patra (2020) <doi:10.3150/19-BEJ1183>.

Structural multivariate-univariate linear mixed model solver for estimation of multiple random effects with unknown variance-covariance structures (e.g., heterogeneous and unstructured) and known covariance among levels of random effects (e.g., pedigree and genomic relationship matrices) (Covarrubias-Pazaran, 2016 <doi:10.1371/journal.pone.0156744>; Maier et al., 2015 <doi:10.1016/j.ajhg.2014.12.006>; Jensen et al., 1997). REML estimates can be obtained using the Direct-Inversion Newton-Raphson and Direct-Inversion Average Information algorithms for the problems r x r (r being the number of records) or using the Henderson-based average information algorithm for the problem c x c (c being the number of coefficients to estimate). Spatial models can also be fitted using the two-dimensional spline functionality available.

Inference on panel data using spatiotemporal partially-observed Markov process (SpatPOMP) models. The spatPomp package extends pomp to include algorithms taking advantage of the spatial structure in order to assist with handling high dimensional processes. See Asfaw et al. (2024) <doi:10.48550/arXiv.2101.01157> for further description of the package.

Gives design points from a sequential full factorial-based Latin hypercube design, as described in Duan, Ankenman, Sanchez, and Sanchez (2015, Technometrics, <doi:10.1080/00401706.2015.1108233>).

Develop spatial interaction models (SIMs). SIMs predict the amount of interaction, for example number of trips per day, between geographic entities representing trip origins and destinations. Contains functions for creating origin-destination datasets from geographic input datasets and calculating movement between origin-destination pairs with constrained, production-constrained, and attraction-constrained models (Wilson 1979) <doi:10.1068/a030001>.

This package provides a flexible tool for simulating complex longitudinal data using structural equations, with emphasis on problems in causal inference. Specify interventions and simulate from intervened data generating distributions. Define and evaluate treatment-specific means, the average treatment effects and coefficients from working marginal structural models. User interface designed to facilitate the conduct of transparent and reproducible simulation studies, and allows concise expression of complex functional dependencies for a large number of time-varying nodes. See the package vignette for more information, documentation and examples.

This package provides a single, phenome-wide permutation of large-scale biobank data. When a large number of phenotypes are analyzed in parallel, a single permutation across all phenotypes followed by genetic association analyses of the permuted data enables estimation of false discovery rates (FDRs) across the phenome. These FDR estimates provide a significance criterion for interpreting genetic associations in a biobank context. For the basic permutation of unrelated samples, this package takes a sample-by-variable file with ID, genotypic covariates, phenotypic covariates, and phenotypes as input. For data with related samples, it also takes a file with sample pair-wise identity-by-descent information. The function outputs a permuted sample-by-variable file ready for genome-wide association analysis. See Annis et al. (2021) <doi:10.21203/rs.3.rs-873449/v1> for details.

This package provides comprehensive analytics, reporting, and testing capabilities for systematic review search strategies. The package focuses on validating search performance, generating standardized PRISMA'-compliant reports, and ensuring reproducibility in evidence synthesis. Features include precision-recall analysis, cross-database performance comparison, benchmark validation against gold standards, sensitivity analysis, temporal coverage assessment, automated report generation, and statistical comparison of search strategies. Supports multiple export formats including CSV', Excel', RIS', BibTeX', and EndNote'. Includes tools for duplicate detection, search strategy optimization, cross-validation frameworks, meta-analysis of benchmark results, power analysis for study design, and reproducibility package creation. Optionally connects to PubMed for direct database searching and real-time strategy comparison using the E-utilities API'. Enhanced with bootstrap comparison methods, McNemar test for strategy evaluation, and comprehensive visualization tools for performance assessment. Methods based on Manning et al. (2008) for information retrieval metrics, Moher et al. (2009) for PRISMA guidelines, and Sampson et al. (2006) for systematic review search methodology.

Simulate complex traits given a SNP genotype matrix and model parameters (the desired heritability, number of causal loci, and either the true ancestral allele frequencies used to generate the genotypes or the mean kinship for a real dataset). Emphasis on avoiding common biases due to the use of estimated allele frequencies. The code selects random loci to be causal, constructs coefficients for these loci and random independent non-genetic effects, and can optionally generate random group effects. Traits can follow three models: random coefficients, fixed effect sizes, and infinitesimal (multivariate normal). GWAS method benchmarking functions are also provided. Described in Yao and Ochoa (2022) <doi:10.1101/2022.03.25.485885>.

This package provides tools to compute and assess significance of early-warnings signals (EWS) of ecosystem degradation. EWS are spatial metrics derived from raster data -- e.g. spatial autocorrelation -- that increase before an ecosystem undergoes a non-linear transition (Genin et al. (2018) <doi:10.1111/2041-210X.13058>).

Statistical Methods to Analyse Sensory Data. SensoMineR: A package for sensory data analysis. S. Le and F. Husson (2008).

Identify sudden gains based on the three criteria outlined by Tang and DeRubeis (1999) <doi:10.1037/0022-006X.67.6.894> to a selection of repeated measures. Sudden losses, defined as the opposite of sudden gains can also be identified. Two different datasets can be created, one including all sudden gains/losses and one including one selected sudden gain/loss for each case. It can extract scores around sudden gains/losses. It can plot the average change around sudden gains/losses and trajectories of individual cases.

Short and understandable commands that generate tabulated, formatted, and rounded survey estimates. Mostly a wrapper for the survey package (Lumley (2004) <doi:10.18637/jss.v009.i08> <https://CRAN.R-project.org/package=survey>) that identifies low-precision estimates using the National Center for Health Statistics (NCHS) presentation standards (Parker et al. (2017) <https://www.cdc.gov/nchs/data/series/sr_02/sr02_175.pdf>, Parker et al. (2023) <doi:10.15620/cdc:124368>).

This package provides a spatial population can be generated based on spatially varying regression model under the assumption that observations are collected from a uniform two-dimensional grid consist of (m * m) lattice points with unit distance between any two neighbouring points. For method details see Chao, Liu., Chuanhua, Wei. and Yunan, Su. (2018).<DOI:10.1080/10485252.2018.1499907>. This spatially generated data can be used to test different issues related to the statistical analysis of spatial data. This generated spatial data can be utilized in geographically weighted regression analysis for studying the spatially varying relationships among the variables.