Transfer REDCap (Research Electronic Data Capture) data to a database, specifically optimized for DuckDB'. Processes data in chunks to handle large datasets without exceeding available memory. Features include data labeling, coded value conversion, and hearing a "quack" sound on success.

This package provides an R scripting interface to the open-source SAGA-GIS (System for Automated Geoscientific Analyses Geographical Information System) software. Rsagacmd dynamically generates R functions for every SAGA-GIS geoprocessing tool based on the user's currently installed SAGA-GIS version. These functions are contained within an S3 object and are accessed as a named list of libraries and tools. This structure facilitates an easier scripting experience by organizing the large number of SAGA-GIS geoprocessing tools (>700) by their respective library. Interactive scripting can fully take advantage of code autocompletion tools (e.g. in RStudio'), allowing for each tools syntax to be quickly recognized. Furthermore, the most common types of spatial data (via the terra', sp', and sf packages) along with non-spatial data are automatically passed from R to the SAGA-GIS command line tool for geoprocessing operations, and the results are loaded as the appropriate R object. Outputs from individual SAGA-GIS tools can also be chained using pipes from the magrittr and dplyr packages to combine complex geoprocessing operations together in a single statement. SAGA-GIS is available under a GPLv2 / LGPLv2 licence from <https://sourceforge.net/projects/saga-gis/> including Windows x86/x64 and macOS binaries. SAGA-GIS is also included in Debian/Ubuntu default software repositories. Rsagacmd has currently been tested on SAGA-GIS versions from 2.3.1 to 9.5.1 on Windows, Linux and macOS.

Resampling Stats (http://www.resample.com) is an add-in for running randomization tests in Excel worksheets. The workflow is (1) to define a statistic of interest that can be calculated from a data table, (2) to randomize rows ad/or columns of a data table to simulate a null hypothesis and (3) and to score the value of the statistic from many randomizations. The relative frequency distribution of the statistic in the simulations is then used to infer the probability of the observed value be generated by the null process (probability of Type I error). This package intends to translate this logic for R for teaching purposes. Keeping the original workflow is favored over performance.

This is an extension of the regression-based causal mediation analysis first proposed by Valeri and VanderWeele (2013) <doi:10.1037/a0031034> and Valeri and VanderWeele (2015) <doi:10.1097/EDE.0000000000000253>). It supports including effect measure modification by covariates(treatment-covariate and mediator-covariate product terms in mediator and outcome regression models) as proposed by Li et al (2023) <doi:10.1097/EDE.0000000000001643>. It also accommodates the original SAS macro and PROC CAUSALMED procedure in SAS when there is no effect measure modification. Linear and logistic models are supported for the mediator model. Linear, logistic, loglinear, Poisson, negative binomial, Cox, and accelerated failure time (exponential and Weibull) models are supported for the outcome model.

This package provides methods and tools for Singular Spectrum Analysis including decomposition, forecasting and gap-filling for univariate and multivariate time series. General description of the methods with many examples can be found in the book Golyandina (2018, <doi:10.1007/978-3-662-57380-8>). See citation("Rssa") for details.

Quantifies and explains end-to-end traceability between clinical submission artifacts (ADaM (Analysis Data Model) outputs, derivations, SDTM (Study Data Tabulation Model) sources, specs, code). Builds trace models from metadata and mapping sheets, computes trace levels, and emits standardized R4SUB (R for Regulatory Submission) evidence table rows via r4subcore'.

Utilities for processing input and output files associated with the Raven Hydrological Modelling Framework. Includes various plotting functions, model diagnostics, reading output files into extensible time series format, and support for writing Raven input files. The RavenR package is also archived at Chlumsky et al. (2020) <doi:10.5281/zenodo.4248183>. The Raven Hydrologic Modelling Framework method can be referenced with Craig et al. (2020) <doi:10.1016/j.envsoft.2020.104728>.

Routines that allow the user to run a large number of goodness-of-fit tests. It allows for data to be continuous or discrete. It includes routines to estimate the power of the tests and display them as a power graph. The routine run.studies allows a user to quickly study the power of a new method and how it compares to some of the standard ones.

Implementation of the algorithms (with minor modifications) to correct bias in quantitative DNA methylation analyses as described by Moskalev et al. (2011) <doi:10.1093/nar/gkr213>. Publication: Kapsner et al. (2021) <doi:10.1002/ijc.33681>.

This package performs robust and sparse correlation matrix estimation. Robustness is achieved based on a simple robust pairwise correlation estimator, while sparsity is obtained based on thresholding. The optimal thresholding is tuned via cross-validation. See Serra, Coretto, Fratello and Tagliaferri (2018) <doi:10.1093/bioinformatics/btx642>.

An implementation to compute an optimal adaptive allocation rule using deep reinforcement learning in a dose-response study (Matsuura et al. (2022) <doi:10.1002/sim.9247>). The adaptive allocation rule can directly optimize a performance metric, such as power, accuracy of the estimated target dose, or mean absolute error over the estimated dose-response curve.

Read the data from Origin(R) project files ('*.opj') <https://www.originlab.com/doc/User-Guide/Origin-File-Types>. No write support is planned.

This package provides functions for simulating Markov chains using the Barker proposal to compute Markov chain Monte Carlo (MCMC) estimates of expectations with respect to a target distribution on a real-valued vector space. The Barker proposal, described in Livingstone and Zanella (2022) <doi:10.1111/rssb.12482>, is a gradient-based MCMC algorithm inspired by the Barker accept-reject rule. It combines the robustness of simpler MCMC schemes, such as random-walk Metropolis, with the efficiency of gradient-based methods, such as the Metropolis adjusted Langevin algorithm. The key function provided by the package is sample_chain(), which allows sampling a Markov chain with a specified target distribution as its stationary distribution. The chain is sampled by generating proposals and accepting or rejecting them using a Metropolis-Hasting acceptance rule. During an initial warm-up stage, the parameters of the proposal distribution can be adapted, with adapters available to both: tune the scale of the proposals by coercing the average acceptance rate to a target value; tune the shape of the proposals to match covariance estimates under the target distribution. As well as the default Barker proposal, the package also provides implementations of alternative proposal distributions, such as (Gaussian) random walk and Langevin proposals. Optionally, if BridgeStan's R interface <https://roualdes.us/bridgestan/latest/languages/r.html>, available on GitHub <https://github.com/roualdes/bridgestan>, is installed, then BridgeStan can be used to specify the target distribution to sample from.

This package provides a toolkit for making antigenic maps from immunological assay data, in order to quantify and visualize antigenic differences between different pathogen strains as described in Smith et al. (2004) <doi:10.1126/science.1097211> and used in the World Health Organization influenza vaccine strain selection process. Additional functions allow for the diagnostic evaluation of antigenic maps and an interactive viewer is provided to explore antigenic relationships amongst several strains and incorporate the visualization of associated genetic information.

Analyzing the performance of artificial intelligence (AI) systems/algorithms characterized by a search-and-report strategy. Historically observer performance has dealt with measuring radiologists performances in search tasks, e.g., searching for lesions in medical images and reporting them, but the implicit location information has been ignored. The implemented methods apply to analyzing the absolute and relative performances of AI systems, comparing AI performance to a group of human readers or optimizing the reporting threshold of an AI system. In addition to performing historical receiver operating receiver operating characteristic (ROC) analysis (localization information ignored), the software also performs free-response receiver operating characteristic (FROC) analysis, where lesion localization information is used. A book using the software has been published: Chakraborty DP: Observer Performance Methods for Diagnostic Imaging - Foundations, Modeling, and Applications with R-Based Examples, Taylor-Francis LLC; 2017: <https://www.routledge.com/Observer-Performance-Methods-for-Diagnostic-Imaging-Foundations-Modeling/Chakraborty/p/book/9781482214840>. Online updates to this book, which use the software, are at <https://dpc10ster.github.io/RJafrocQuickStart/>, <https://dpc10ster.github.io/RJafrocRocBook/> and at <https://dpc10ster.github.io/RJafrocFrocBook/>. Supported data collection paradigms are the ROC, FROC and the location ROC (LROC). ROC data consists of single ratings per images, where a rating is the perceived confidence level that the image is that of a diseased patient. An ROC curve is a plot of true positive fraction vs. false positive fraction. FROC data consists of a variable number (zero or more) of mark-rating pairs per image, where a mark is the location of a reported suspicious region and the rating is the confidence level that it is a real lesion. LROC data consists of a rating and a location of the most suspicious region, for every image. Four models of observer performance, and curve-fitting software, are implemented: the binormal model (BM), the contaminated binormal model (CBM), the correlated contaminated binormal model (CORCBM), and the radiological search model (RSM). Unlike the binormal model, CBM, CORCBM and RSM predict proper ROC curves that do not inappropriately cross the chance diagonal. Additionally, RSM parameters are related to search performance (not measured in conventional ROC analysis) and classification performance. Search performance refers to finding lesions, i.e., true positives, while simultaneously not finding false positive locations. Classification performance measures the ability to distinguish between true and false positive locations. Knowing these separate performances allows principled optimization of reader or AI system performance. This package supersedes Windows JAFROC (jackknife alternative FROC) software V4.2.1, <https://github.com/dpc10ster/WindowsJafroc>. Package functions are organized as follows. Data file related function names are preceded by Df', curve fitting functions by Fit', included data sets by dataset', plotting functions by Plot', significance testing functions by St', sample size related functions by Ss', data simulation functions by Simulate and utility functions by Util'. Implemented are figures of merit (FOMs) for quantifying performance and functions for visualizing empirical or fitted operating characteristics: e.g., ROC, FROC, alternative FROC (AFROC) and weighted AFROC (wAFROC) curves. For fully crossed study designs significance testing of reader-averaged FOM differences between modalities is implemented via either Dorfman-Berbaum-Metz or the Obuchowski-Rockette methods. Also implemented is single treatment analysis, which allows comparison of performance of a group of radiologists to a specified value, or comparison of AI to a group of radiologists interpreting the same cases. Crossed-modality analysis is implemented wherein there are two crossed treatment factors and the aim is to determined performance in each treatment factor averaged over all levels of the second factor. Sample size estimation tools are provided for ROC and FROC studies; these use estimates of the relevant variances from a pilot study to predict required numbers of readers and cases in a pivotal study to achieve the desired power. Utility and data file manipulation functions allow data to be read in any of the currently used input formats, including Excel, and the results of the analysis can be viewed in text or Excel output files. The methods are illustrated with several included datasets from the author's collaborations. This update includes improvements to the code, some as a result of user-reported bugs and new feature requests, and others discovered during ongoing testing and code simplification.

Assessing and comparing risk prediction rules for clustered data. The method is based on the paper: Rosner B, Qiu W, and Lee MLT.(2013) <doi: 10.1007/s10985-012-9240-6>.

R implementation of SIDES-based subgroup search algorithms (Lipkovich et al. (2017) <doi:10.1002/sim.7064>).

Fit and deploy rotation forest models ("Rodriguez, J.J., Kuncheva, L.I., 2006. Rotation forest: A new classifier ensemble method. IEEE Trans. Pattern Anal. Mach. Intell. 28, 1619-1630 <doi:10.1109/TPAMI.2006.211>") for binary classification. Rotation forest is an ensemble method where each base classifier (tree) is fit on the principal components of the variables of random partitions of the feature set.

Compute time-dependent Incident/dynamic accuracy measures (ROC curve, AUC, integrated AUC )from censored survival data under proportional or non-proportional hazard assumption of Heagerty & Zheng (Biometrics, Vol 61 No 1, 2005, PP 92-105).

Used for generating randomized community matrices under strict range cohesion. The package can handle data where species occurrence are recorded across sites ordered along gradients such as elevation and latitude, as well as species occurrences recorded on spatial grids with known geographic coordinates.

FRACTRAN is an obscure yet tantalizing programming language invented by John Conway of Game of Life fame. The code consists of a sequence of fractions. The rules are simple. First, select an integer to initialize the process. Second, multiply the integer by the first fraction. If an integer results, start again with the new integer. If not, try the next fraction. Finally, if no such multiplication yields an integer, terminate the program. For more information, see <https://en.wikipedia.org/wiki/FRACTRAN> .

Adds menu items to the R Commander for implementing case 1 (object case) best-worst scaling (BWS1) from designing choice sets to measuring preferences for items. BWS1 is a question-based survey method that constructs various combinations of items (choice sets) using the experimental designs, asks respondents to select the best and worst items in each choice set, and then measures preferences for the items by analyzing the responses. For details, refer to Aizaki and Fogarty (2023) <doi:10.1016/j.jocm.2022.100394>.

We rewrite of RAMpath software developed by John McArdle and Steven Boker as an R package. In addition to performing regular SEM analysis through the R package lavaan, RAMpath has unique features. First, it can generate path diagrams according to a given model. Second, it can display path tracing rules through path diagrams and decompose total effects into their respective direct and indirect effects as well as decompose variance and covariance into individual bridges. Furthermore, RAMpath can fit dynamic system models automatically based on latent change scores and generate vector field plots based upon results obtained from a bivariate dynamic system. Starting version 0.4, RAMpath can conduct power analysis for both univariate and bivariate latent change score models.

Random Hazard Forests (RHF) extend Random Survival Forests (RSF) by directly estimating the hazard function and by accommodating time-dependent covariates through counting-process style inputs. The package fits tree ensembles for dynamic survival prediction, returning hazard, cumulative hazard, integrated hazard, and related performance summaries for training and test data. The methods build on Random Survival Forests described by Ishwaran et al. (2008) <doi:10.1214/08-AOAS169> and on nonparametric hazard modeling with time-dependent covariates described by Lee et al. (2021) <doi:10.1214/20-AOS2028>.