This package provides methods to scan RR interval data for Premature Ventricular Complexes (PVCs) and parameterise and plot the resulting Heart Rate Turbulence (HRT). The methodology of HRT analysis is based on the original publication by Schmidt et al. <doi:10.1016/S0140-6736(98)08428-1> and extended with suggestions from <doi:10.1088/1361-6579/ab98b3>.

The Google FarmHash family of hash functions is used by the Google BigQuery data warehouse via the FARM_FINGERPRINT function. This package permits to calculate these hash digest fingerprints directly from R, and uses the included FarmHash files written by G. Pike and copyrighted by Google, Inc.

Visualize your favorite XKCD comic strip directly from R. Includes full-text search with BM25 ranking and semantic similarity search via local GloVe embeddings, powered by a local DuckDB cache.

Doubly ranked tests are nonparametric tests for grouped functional and multivariate data. The testing procedure first ranks a matrix (or three dimensional array) of data by column (if a matrix) or by cell (across the third dimension if an array). By default, it calculates a sufficient statistic for the subject's order within the sample using the observed ranks, taken over the columns or cells. Depending on the number of groups, G, the summarized ranks are then analyzed using either a Wilcoxon Rank Sum test (G = 2) or a Kruskal-Wallis (G greater than 2).

This package performs Wavelet Lifting Transforms focusing on signal denoising and functional data analysis (FDA). Implements a hybrid architecture with a zero-allocation C++ core for high-performance processing. Features include unified offline (batch) denoising, causal (real-time) filtering using a ring buffer engine, and adaptive recursive thresholding.

Estimates life tables, specifically (crude) death rates and (raw and graduated) death probabilities, using rolling windows in one (e.g., age), two (e.g., age and time) or three (e.g., age, time and income) dimensions. The package can also be utilised for summarising statistics and smoothing continuous variables through rolling windows in other domains, such as estimating averages of self-positioning ideology in political science. Acknowledgements: The authors wish to thank Ministerio de Ciencia, Innovación y Universidades (grant PID2021-128228NB-I00) and Generalitat Valenciana (grants HIECPU/2023/2, Conselleria de Hacienda, Economà a y Administración Pública, and CIGE/2023/7, Conselleria de Educación, Cultura, Universidades y Empleo) for supporting this research.

Clusters functionally related biological terms from gene set enrichment results. Terms are compared by the overlap of their gene sets using Cohen's kappa, the Jaccard index, or the Dice coefficient, and the resulting similarity matrix is grouped either by agglomerative hierarchical clustering with single, complete, average, or Ward linkage, or by the seed-and-merge procedure of the DAVID functional classification tool. The distance and clustering routines are written in C++ for speed. The methods are described in Huang et al. (2007) <doi:10.1186/gb-2007-8-9-r183>, Ward (1963) <doi:10.1080/01621459.1963.10500845>, Cohen (1960) <doi:10.1177/001316446002000104>, and Jaccard (1912) <doi:10.1111/j.1469-8137.1912.tb05611.x>.

Native R interface to TMB (Template Model Builder) so models can be written entirely in R rather than C++'. Automatic differentiation, to any order, is available for a rich subset of R features, including linear algebra for dense and sparse matrices, complex arithmetic, Fast Fourier Transform, probability distributions and special functions. RTMB provides easy access to model fitting and validation following the principles of Kristensen, K., Nielsen, A., Berg, C. W., Skaug, H., & Bell, B. M. (2016) <DOI:10.18637/jss.v070.i05> and Thygesen, U.H., Albertsen, C.M., Berg, C.W. et al. (2017) <DOI:10.1007/s10651-017-0372-4>.

Implementation of the algorithms (with minor modifications) to correct bias in quantitative DNA methylation analyses as described by Moskalev et al. (2011) <doi:10.1093/nar/gkr213>. Publication: Kapsner et al. (2021) <doi:10.1002/ijc.33681>.

Execute API calls to the RobinHood <https://robinhood.com> investing platform. Functionality includes accessing account data and current holdings, retrieving investment statistics and quotes, placing and canceling orders, getting market trading hours, searching investments by popular tag, and interacting with watch lists.

Sample size and confidence interval calculations in reversible catalytic models, with applications in malaria research. Further details can be found in the paper by Sepúlveda and Drakeley (2015, <doi:10.1186/s12936-015-0661-z>).

Feature selection and clustering classification under the presence of multivariate outliers in high-dimensional unlabeled data.

This package provides functions to estimate the proportion of treatment effect on the primary outcome that is explained by the treatment effect on the surrogate marker.

This package provides a tool designed to analyze recurrent events when dealing with right-censored data and the potential presence of a terminal event (that prevents further occurrences, like death). It extends the random survival forest algorithm, adapting splitting rules and node estimators to handle complexities of recurrent events. The methodology is fully described in Murris, J., Bouaziz, O., Jakubczak, M., Katsahian, S., & Lavenu, A. (2024) (<https://hal.science/hal-04612431v1/document>).

We provide an implementation for Sum of Ranking Differences (SRD), a novel statistical test introduced by Héberger (2010) <doi:10.1016/j.trac.2009.09.009>. The test allows the comparison of different solutions through a reference by first performing a rank transformation on the input, then calculating and comparing the distances between the solutions and the reference - the latter is measured in the L1 norm. The reference can be an external benchmark (e.g. an established gold standard) or can be aggregated from the data. The calculated distances, called SRD scores, are validated in two ways, see Héberger and Kollár-Hunek (2011) <doi:10.1002/cem.1320>. A randomization test (also called permutation test) compares the SRD scores of the solutions to the SRD scores of randomly generated rankings. The second validation option is cross-validation that checks whether the rankings generated from the solutions come from the same distribution or not. For a detailed analysis about the cross-validation process see Sziklai, Baranyi and Héberger (2021) <doi:10.48550/arXiv.2105.11939>. The package offers a wide array of features related to SRD including the computation of the SRD scores, validation options, input preprocessing and plotting tools.

Construct an explainable nomogram for a machine learning (ML) model to improve availability of an ML prediction model in addition to a computer application, particularly in a situation where a computer, a mobile phone, an internet connection, or the application accessibility are unreliable. This package enables a nomogram creation for any ML prediction models, which is conventionally limited to only a linear/logistic regression model. This nomogram may indicate the explainability value per feature, e.g., the Shapley additive explanation value, for each individual. However, this package only allows a nomogram creation for a model using categorical without or with single numerical predictors. Detailed methodologies and examples are documented in our vignette, available at <https://htmlpreview.github.io/?https://github.com/herdiantrisufriyana/rmlnomogram/blob/master/doc/ml_nomogram_exemplar.html>.

MCMC based sampling of binary matrices with fixed margins as used in exact Rasch model tests.

Risk-related information (like the prevalence of conditions, the sensitivity and specificity of diagnostic tests, or the effectiveness of interventions or treatments) can be expressed in terms of frequencies or probabilities. By providing a toolbox of corresponding metrics and representations, riskyr computes, translates, and visualizes risk-related information in a variety of ways. Adopting multiple complementary perspectives provides insights into the interplay between key parameters and renders teaching and training programs on risk literacy more transparent (see <doi:10.3389/fpsyg.2020.567817>, for details).

Download and handle spatial and temporal data from the CAMELS-CL dataset (Catchment Attributes and Meteorology for Large Sample Studies, Chile) <https://camels.cr2.cl/>, developed by Alvarez-Garreton et al. (2018) <doi:10.5194/hess-22-5817-2018>. The package does not generate new data, it only facilitates direct access to the original dataset for hydrological analyses.

Fast and efficient computation of rolling and expanding eigenanalysis for time-series data. The rolleigen package decomposes the covariance matrix of the explanatory variables into eigenvalues and eigenvectors to perform principal component analysis (Pearson, 1901, <doi:10.1080/14786440109462720>; Hotelling, 1933, <doi:10.1037/h0071325>) and principal component regression (Massy, 1965, <doi:10.1080/01621459.1965.10480787>) over rolling and expanding windows. For each window, the eigenvalues and eigenvectors are computed from the covariance matrix and, optionally, ordered from largest to smallest to summarize the directions of greatest variation in the data. A subset of leading components is then used to fit a regression that mitigates collinearity in the explanatory variables. Use cases include dimensionality reduction, factor extraction, and regression on collinear explanatory variables. The package supports rolling and expanding windows, weights, and handling of missing values via the min_obs, complete_obs, and na_restore arguments. The implementation uses the online and offline algorithms from the roll package to compute rolling and expanding cross-products efficiently, with parallelism across columns and windows provided by RcppParallel'.

Create production-ready Rich Text Format (RTF) tables and figures with flexible format.

Use trend filtering, a type of regularized nonparametric regression, to estimate the instantaneous reproduction number, also called Rt. This value roughly says how many new infections will result from each new infection today. Values larger than 1 indicate that an epidemic is growing while those less than 1 indicate decline. For more details about this methodology, see Liu, Cai, Gustafson, and McDonald (2024) <doi:10.1371/journal.pcbi.1012324>.

This web client interfaces Unpaywall <https://unpaywall.org/products/api>, formerly oaDOI, a service finding free full-texts of academic papers by linking DOIs with open access journals and repositories. It provides unified access to various data sources for open access full-text links including Crossref and the Directory of Open Access Journals (DOAJ). API usage is free and no registration is required.

This package provides functions to read and write ImageJ (<https://imagej.net>) Region of Interest (ROI) files, to plot the ROIs and to convert them to spatstat (<https://spatstat.org/>) spatial patterns.