Nonparametric test of independence between a pair of spatial objects (random fields, point processes) based on random shifts with torus or variance correction. See MrkviÄ ka et al. (2021) <doi:10.1016/j.spasta.2020.100430>, DvoŠák et al. (2022) <doi:10.1111/insr.12503>, DvoŠák and MrkviÄ ka (2024) <doi:10.1080/10618600.2024.2357626>.
This package provides a first implementation of automated parsing of user stories, when used to defined functional requirements for operational research mathematical models. It allows reading user stories, splitting them on the who-what-why template, and classifying them according to the parts of the mathematical model that they represent. Also provides semantic grouping of stories, for project management purposes.
Analyse common types of plant phenotyping data, provide a simplified interface to longitudinal growth modeling and select Bayesian statistics, and streamline use of PlantCV output. Several Bayesian methods and reporting guidelines for Bayesian methods are described in Kruschke (2018) <doi:10.1177/2515245918771304>, Kruschke (2013) <doi:10.1037/a0029146>, and Kruschke (2021) <doi:10.1038/s41562-021-01177-7>.
Seven different methods for multiple testing problems. The SGoF-type methods (see for example, Carvajal Rodrà guez et al., 2009 <doi:10.1186/1471-2105-10-209>; de Uña à lvarez, 2012 <doi:10.1515/1544-6115.1812>; Castro Conde et al., 2015 <doi:10.1177/0962280215597580>) and the BH and BY false discovery rate controlling procedures.
This package implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.
This package provides functions for implementing the targeted gold standard (GS) testing. You provide the true disease or treatment failure status and the risk score, tell TGST the availability of GS tests and which method to use, and it returns the optimal tripartite rules. Please refer to Liu et al. (2013) <doi:10.1080/01621459.2013.810149> for more details.
The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but tcpl can be used to support diverse chemical screening efforts.
Population genetic data such as Single Nucleotide Polymorphisms (SNPs) is often used to identify genomic regions that have been under recent natural or artificial selection and might provide clues about the molecular mechanisms of adaptation. One approach, the concept of an Extended Haplotype Homozygosity (EHH), introduced by (Sabeti 2002) <doi:10.1038/nature01140>, has given rise to several statistics designed for whole genome scans. The package provides functions to compute three of these, namely: iHS (Voight 2006) <doi:10.1371/journal.pbio.0040072> for detecting positive or Darwinian selection within a single population as well as Rsb (Tang 2007) <doi:10.1371/journal.pbio.0050171> and XP-EHH (Sabeti 2007) <doi:10.1038/nature06250>, targeted at differential selection between two populations. Various plotting functions are included to facilitate visualization and interpretation of these statistics.
The Recode library converts files between character sets and usages. It recognises or produces over 200 different character sets (or about 300 if combined with an iconv library) and transliterates files between almost any pair. When exact transliteration are not possible, it gets rid of offending characters or falls back on approximations. The recode program is a handy front-end to the library.
Defining the identity of a cell is fundamental to understand the heterogeneity of cells to various environmental signals and perturbations. We present Cepo, a new method to explore cell identities from single-cell RNA-sequencing data using differential stability as a new metric to define cell identity genes. Cepo computes cell-type specific gene statistics pertaining to differential stable gene expression.
Target capture experiments combine hybridization-based (in solution or on microarrays) capture and enrichment of genomic regions of interest (e.g. the exome) with high throughput sequencing of the captured DNA fragments. This package provides functionalities for assessing and visualizing the quality of the target enrichment process, like specificity and sensitivity of the capture, per-target read coverage and so on.
The package provides S4 classes and methods to filter, summarise and visualise genetic variation data stored in VCF files. In particular, the package extends the FilterRules class (S4Vectors package) to define news classes of filter rules applicable to the various slots of VCF objects. Functionalities are integrated and demonstrated in a Shiny web-application, the Shiny Variant Explorer (tSVE).
This package provides functions provide risk projections of invasive breast cancer based on Gail model according to National Cancer Institute's Breast Cancer Risk Assessment Tool algorithm for specified race/ethnic groups and age intervals. Gail MH, Brinton LA, et al (1989) <doi:10.1093/jnci/81.24.1879>. Marthew PB, Gail MH, et al (2016) <doi:10.1093/jnci/djw215>.
We use a Bayesian approach to run individual patient data meta-analysis and network meta-analysis using JAGS'. The methods incorporate shrinkage methods and calculate patient-specific treatment effects as described in Seo et al. (2021) <DOI:10.1002/sim.8859>. This package also includes user-friendly functions that impute missing data in an individual patient data using mice-related packages.
This package provides tools to help the design and analysis of resilient non-inferiority trials. These include functions for sample size calculations and analyses of trials, with either a risk difference, risk ratio or arc-sine difference margin, and a function to run simulations to design a trial with the methods described in Quartagno et al. (2019) <arXiv:1905.00241>.
If translate English or Chinese sentence, there is a faster way for R user. You can pass in an English or Chinese sentence, ecce package support both English and Chinese translation. It also support browse translation results in website. In addition, also support obtain the pinyin of the Chinese character, you can more easily understand the pronunciation of the Chinese character.
This package provides Generalized Inferences based on exact distributions and exact probability statements for mixed effect models, provided by such papers as Weerahandi and Yu (2020) <doi:10.1186/s40488-020-00105-w> under the widely used Compound Symmetric Covariance structure. The package returns the estimation of the coefficients in random and fixed part of the mixed models by generalized inference.
This package infers a topology of relationships between different datasets, such as multi-omics and phenotypic data recorded on the same samples. We based this methodology on the RV coefficient (Robert & Escoufier, 1976, <doi:10.2307/2347233>), a measure of matrix correlation, which we have extended for partial matrix correlations and binary data (Aben et al., 2018, <doi:10.1101/293993>).
This package provides functions for analyzing multiple choice items. These analyses include the convertion of student response into binaty data (correct/incorrect), the computation of the number of corrected responses and grade for each subject, the calculation of item difficulty and discrimination, the computation of the frecuency and point-biserial correlation for each distractor and the graphical analysis of each item.
This package provides tools to assess model fit and identify misfitting items for Rasch models (RM) and partial credit models (PCM). Included are item fit statistics, item characteristic curves, item-restscore association, conditional likelihood ratio tests, assessment of measurement error, estimates of the reliability and test targeting as described in Christensen et al. (Eds.) (2013, ISBN:978-1-84821-222-0).
The inti package is part of the inkaverse project for developing different procedures and tools used in plant science and experimental designs. The mean aim of the package is to support researchers during the planning of experiments and data collection (tarpuy()), data analysis and graphics (yupana()) , and scientific writing. Learn more about the inkaverse project at <https://inkaverse.com/>.
An educational package for teaching statistics and mathematics in both primary and higher education. The objective is to assist in the teaching/learning process, both for student study planning and teacher teaching strategies. The leem package aims to provide, in a simple yet in-depth manner, knowledge of statistics and mathematics to anyone who wants to study these areas of knowledge.
The IRLS (Iteratively Reweighted Least Squares) and GMM (Generalized Method of Moments) methods are applied to estimate mixed correlation coefficient matrix (Pearson, Polyseries, Polychoric), which can be estimated in pairs or simultaneously. For more information see Peng Zhang and Ben Liu (2024) <doi:10.1080/10618600.2023.2257251>; Ben Liu and Peng Zhang (2024) <doi:10.48550/arXiv.2404.06781>.
This package provides functions for diagnostic meta-analysis. Next to basic analysis and visualization the bivariate Model of Reitsma et al. (2005) that is equivalent to the HSROC of Rutter & Gatsonis (2001) can be fitted. A new approach based to diagnostic meta-analysis of Holling et al. (2012) is also available. Standard methods like summary, plot and so on are provided.