The saemix package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. It (i) computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, (ii) provides standard errors for the maximum likelihood estimator (iii) estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm (see Comets et al. (2017) <doi:10.18637/jss.v080.i03>). Many applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group. The full PDF documentation for the package including references about the algorithm and examples can be downloaded on the github of the IAME research institute for saemix': <https://github.com/iame-researchCenter/saemix/blob/7638e1b09ccb01cdff173068e01c266e906f76eb/docsaem.pdf>.

Computes the sBIC for various singular model collections including: binomial mixtures, factor analysis models, Gaussian mixtures, latent forests, latent class analyses, and reduced rank regressions.

Download files hosted on AWS S3 (Amazon Web Services Simple Storage Service; <https://aws.amazon.com/s3/>) to a local directory based on their URI. Avoid downloading files that are already present locally. Allow for customization of where to store downloaded files.

This package provides a SAS interface, through SASPy'(<https://sassoftware.github.io/saspy/>) and reticulate'(<https://rstudio.github.io/reticulate/>). This package helps you create SAS sessions, execute SAS code in remote SAS servers, retrieve execution results and log, and exchange datasets between SAS and R'. It also helps you to install SASPy and create a configuration file for the connection. Please review the SASPy license file as instructed so that you comply with its separate and independent license.

Makes the React library Chakra UI usable in Shiny apps. Chakra UI components include alert dialogs, drawers (sliding panels), menus, modals, popovers, sliders, and more.

An efficient implementation of SCCI using Rcpp'. SCCI is short for the Stochastic Complexity-based Conditional Independence criterium (Marx and Vreeken, 2019). SCCI is an asymptotically unbiased and L2 consistent estimator of (conditional) mutual information for discrete data.

Collision Risk Models for avian fauna (seabird and migratory birds) at offshore wind farms. The base deterministic model is derived from Band (2012) <https://tethys.pnnl.gov/publications/using-collision-risk-model-assess-bird-collision-risks-offshore-wind-farms>. This was further expanded on by Masden (2015) <doi:10.7489/1659-1> and code used here is heavily derived from this work with input from Dr A. Cook at the British Trust for Ornithology. These collision risk models are useful for marine ornithologists who are working in the offshore wind industry, particularly in UK waters. However, many of the species included in the stochastic collision risk models can also be found in the North Atlantic in the United States and Canada, and could be applied there.

This package provides a collection of functions for processing raw data from Stream Temperature, Intermittency, and Conductivity (STIC) loggers. STICr (pronounced "sticker") includes functions for tidying, calibrating, classifying, and doing quality checks on data from STIC sensors. Some package functionality is described in Wheeler/Zipper et al. (2023) <doi:10.31223/X5636K>.

This is a compendium of C++ routines useful for Bayesian statistics. We steal other people's C++ code, repurpose it, and export it so developers of R packages can use it in their C++ code. We actually don't steal anything, or claim that Thomas Bayes did, but copy code that is compatible with our GPL 3 licence, fully acknowledging the authorship of the original code.

Generate objects that simulate survival times. Random values for the distributions are generated using the method described by Bender (2003) <https://epub.ub.uni-muenchen.de/id/eprint/1716> and Leemis (1987) in Operations Research, 35(6), 892â 894.

This package provides a suite of statistical methods for analysis of single-cell omics data including linear model-based methods for differential abundance analysis for individual level single-cell RNA-seq data. For more details see Zhang, et al. (Submitted to Bioinformatics)<https://github.com/Lujun995/DiSC_Replication_Code>.

An extension of the Fisher Scoring Algorithm to combine PLS regression with GLM estimation in the multivariate context. Covariates can also be grouped in themes.

Fit a spatial-temporal occupancy models using a probit formulation instead of a traditional logit model.

This package provides functions to take samples of data, sample size estimation and getting useful estimators such as total, mean, proportion about its population using simple random, stratified, systematic and cluster sampling.

This package provides a complete suite of tools for interacting with the Survey Solutions GraphQL API <https://demo.mysurvey.solutions/graphql/>. This package encompasses all currently available queries and mutations, including the latest features for map uploads. It is built on the modern httr2 package, offering a streamlined and efficient interface without relying on external GraphQL client packages. In addition to core API functionalities, the package includes a range of helper functions designed to facilitate the use of available query filters.

Rapidly build accurate genetic prediction models for genome-wide association or whole-genome sequencing study data by smooth-threshold multivariate genetic prediction (STMGP) method. Variable selection is performed using marginal association test p-values with an optimal p-value cutoff selected by Cp-type criterion. Quantitative and binary traits are modeled respectively via linear and logistic regression models. A function that works through PLINK software (Purcell et al. 2007 <DOI:10.1086/519795>, Chang et al. 2015 <DOI:10.1186/s13742-015-0047-8>) <https://www.cog-genomics.org/plink2> is provided. Covariates can be included in regression model.

Calculates sample size for various scenarios, such as sample size to estimate population proportion with stated absolute or relative precision, testing a single proportion with a reference value, to estimate the population mean with stated absolute or relative precision, testing single mean with a reference value and sample size for comparing two unpaired or independent means, comparing two paired means, the sample size For case control studies, estimating the odds ratio with stated precision, testing the odds ratio with a reference value, estimating relative risk with stated precision, testing relative risk with a reference value, testing a correlation coefficient with a specified value, etc. <https://www.academia.edu/39511442/Adequacy_of_Sample_Size_in_Health_Studies#:~:text=Determining%20the%20sample%20size%20for,may%20yield%20statistically%20inconclusive%20results.>.

Plays the game of Snakes and Ladders and has tools for analyses. The tools included allow you to find the average moves to win, frequency of each square, importance of the snakes and the ladders, the most common square and the plotting of the game played.

This package provides wrappers for common activity patterns in simmer trajectories.

We provide functions for estimation and inference of locally-stationary time series using the sieve methods and bootstrapping procedure. In addition, it also contains functions to generate Daubechies and Coiflet wavelet by Cascade algorithm and to process data visualization.

Speeds up the process of loading raw data from MBA (Multiplex Bead Assay) examinations, performs quality control checks, and automatically normalises the data, preparing it for more advanced, downstream tasks. The main objective of the package is to create a simple environment for a user, who does not necessarily have experience with R language. The package is developed within the project PvSTATEM', which is an international project aiming for malaria elimination.

This package provides a function that behaves nearly as base::source() but implements a caching mechanism on disk, project based. It allows to quasi source() R scripts that gather data but can fail or consume to much time to respond even if nothing new is expected. It comes with tools to check and execute on demand or when cache is invalid the script.

Compute relative or absolute population trends across space and time using predictions from models fitted to ecological population abundance data, as described in Knape (2025) <doi:10.1016/j.ecolind.2025.113435>. The package supports models fitted by mgcv or brms', and draws from posterior predictive distributions.

In the past decade, genome-scale metabolic reconstructions have widely been used to comprehend the systems biology of metabolic pathways within an organism. Different GSMs are constructed using various techniques that require distinct steps, but the input data, information conversion and software tools are neither concisely defined nor mathematically or programmatically formulated in a context-specific manner.The tool that quantitatively and qualitatively specifies each reconstruction steps and can generate a template list of reconstruction steps dynamically selected from a reconstruction step reservoir, constructed based on all available published papers.