This package provides two main functionalities. 1 - Given a system of simultaneous equation, it decomposes the matrix of coefficients weighting the endogenous variables into three submatrices: one includes the subset of coefficients that have a causal nature in the model, two include the subset of coefficients that have a interdependent nature in the model, either at systematic level or induced by the correlation between error terms. 2 - Given a decomposed model, it tests for the significance of the interdependent relationships acting in the system, via Maximum likelihood and Wald test, which can be built starting from the function output. For theoretical reference see Faliva (1992) <doi:10.1007/BF02589085> and Faliva and Zoia (1994) <doi:10.1007/BF02589041>.

Compute the frequency distribution of a search term in a series of texts. For example, Arthur Conan Doyle wrote a total of 60 Sherlock Holmes stories, comprised of 54 short stories and 4 longer novels. I wanted to test my own subjective impression that, in many of the stories, Sherlock Holmes popularity was used as bait to induce the reader to read a story that is essentially not primarily a Sherlock Holmes story. I used the term "Holmes" as a search pattern, since Watson would frequently address him by name, or use his name to describe something that he was doing. My hypothesis is that the frequency distribution of the search pattern "Holmes" is a good proxy for the degree to which a story is or is not truly a Sherlock Holmes story. The results are presented in a manuscript that is available as a vignette and online at <https://barryzee.github.io/Concordance/index.html>.

We analyzed the nucleotide composition of genes with a special emphasis on stability of DNA sequences. Besides, in a variety of different organisms unequal use of synonymous codons, or codon usage bias, occurs which also show variation among genes in the same genome. Seemingly, codon usage bias is affected by both selective constraints and mutation bias which allows and enables us to examine and detect changes in these two evolutionary forces between genomes or along one genome. Therefore, we determined the codon adaptation index (CAI), effective number of codons (ENC) and codon usage analysis with calculation of the relative synonymous codon usage (RSCU), and subsequently predicted the translation efficiency and accuracy through GC-rich codon usages. Furthermore, we estimated the relative stability of the DNA sequence following calculation of the average free energy (Delta G) and Dimer base-stacking energy level.

This package creates ggplot2'-based visualizations of smooth effects from GAM (Generalized Additive Models) fitted with mgcv and spline effects from GLM (Generalized Linear Models). Supports survey-weighted models ('svyglm', svycoxph') from the survey package, interaction terms, and provides hazard ratio plots with histograms for survival analysis. Wood (2017, ISBN:9781498728331) provides comprehensive methodology for generalized additive models.

This package creates complex heatmaps for single cell RNA-seq data that simultaneously display gene expression levels (as color intensity) and expression percentages (as circle sizes). Supports gene grouping, cell type annotations, and time point comparisons. Built on top of ComplexHeatmap and integrates with Seurat objects. For more details see Gu (2022) <doi:10.1002/imt2.43> and Hao (2024) <doi:10.1038/s41587-023-01767-y>.

An efficient tool for fitting nested mixture models based on a shared set of atoms via Markov Chain Monte Carlo and variational inference algorithms. Specifically, the package implements the common atoms model (Denti et al., 2023), its finite version (similar to D'Angelo et al., 2023), and a hybrid finite-infinite model (D'Angelo and Denti, 2024). All models implement univariate nested mixtures with Gaussian kernels equipped with a normal-inverse gamma prior distribution on the parameters. Additional functions are provided to help analyze the results of the fitting procedure. References: Denti, Camerlenghi, Guindani, Mira (2023) <doi:10.1080/01621459.2021.1933499>, Dâ Angelo, Canale, Yu, Guindani (2023) <doi:10.1111/biom.13626>, Dâ Angelo, Denti (2024) <doi:10.1214/24-BA1458>.

Support for reading and writing files in StatDataML---an XML-based data exchange format.

Estimate networks and causal relationships in complex systems through Structural Equation Modeling. This package also includes functions for importing, weight, manipulate, and fit biological network models within the Structural Equation Modeling framework as outlined in the Supplementary Material of Grassi M, Palluzzi F, Tarantino B (2022) <doi:10.1093/bioinformatics/btac567>.

Holds functions developed by the University of Ottawa's SAiVE (Spatio-temporal Analysis of isotope Variations in the Environment) research group with the intention of facilitating the re-use of code, foster good code writing practices, and to allow others to benefit from the work done by the SAiVE group. Contributions are welcome via the GitHub repository <https://github.com/UO-SAiVE/SAiVE> by group members as well as non-members.

Statistical Methods to Analyse Sensory Data. SensoMineR: A package for sensory data analysis. S. Le and F. Husson (2008).

Adds variable-selection functions for Beta regression models (both mean and phi submodels) so they can be used within the SelectBoost algorithm. Includes stepwise AIC, BIC, and corrected AIC on betareg() fits, gamlss'-based LASSO/Elastic-Net, a pure glmnet iterative re-weighted least squares-based selector with an optional standardization speedup, and C++ helpers for iterative re-weighted least squares working steps and precision updates. Also provides a fastboost_interval() variant for interval responses, comparison helpers, and a flexible simulator simulation_DATA.beta() for interval-valued data. For more details see Bertrand and Maumy (2023) <doi:10.7490/f1000research.1119552.1>.

More easy to get intersection, union or complementary set and combinations.

Accesses raw data via API and calculates social determinants of health measures for user-specified locations in the US, returning them in tidyverse- and sf-compatible data frames.

Simultaneous tests and confidence intervals are provided for one-way experimental designs with one or many normally distributed, primary response variables (endpoints). Differences (Hasler and Hothorn, 2011 <doi:10.2202/1557-4679.1258>) or ratios (Hasler and Hothorn, 2012 <doi:10.1080/19466315.2011.633868>) of means can be considered. Various contrasts can be chosen, unbalanced sample sizes are allowed as well as heterogeneous variances (Hasler and Hothorn, 2008 <doi:10.1002/bimj.200710466>) or covariance matrices (Hasler, 2014 <doi:10.1515/ijb-2012-0015>).

This package provides a collection of classes and methods for working with indexed rectangular data. The index values can be calendar (timeSeries class) or numeric (signalSeries class). Methods are included for aggregation, alignment, merging, and summaries. The code was originally available in S-PLUS'.

Provide utilities to work with solar time, i.e. where noon is exactly when sun culminates. Provides functions for computing sun position and times of sunrise and sunset.

The purpose of this package is to manipulate SVG files that are templates of charts the user wants to produce. In vector graphics one copes with x-/y-coordinates of elements (e.g. lines, rectangles, text). Their scale is often dependent on the program that is used to produce the graphics. In applied statistics one usually has numeric values on a fixed scale (e.g. percentage values between 0 and 100) to show in a chart. Basically, svgtools transforms the statistical values into coordinates and widths/heights of the vector graphics. This is done by stackedBar() for bar charts, by linesSymbols() for charts with lines and/or symbols (dot markers) and scatterSymbols() for scatterplots.

This package provides an S4 class for representing and interacting with sparse plus rank matrices. At the moment the implementation is quite spare, but the plan is eventually subclass Matrix objects.

An implementation of self-exciting point process model for information cascades, which occurs when many people engage in the same acts after observing the actions of others (e.g. post resharings on Facebook or Twitter). It provides functions to estimate the infectiousness of an information cascade and predict its popularity given the observed history. See <http://snap.stanford.edu/seismic/> for more information and datasets.

This package contains several tools for nonlinear regression analyses and general data analysis in biology and agriculture. Contains also datasets for practicing and teaching purposes. Supports the blog: Onofri (2024) "Fixing the bridge between biologists and statisticians" <https://www.statforbiology.com> and the book: Onofri (2024) "Experimental Methods in Agriculture" <https://www.statforbiology.com/_statbookeng/>. The blog is a collection of short articles aimed at improving the efficiency of communication between biologists and statisticians, as pointed out in Kozak (2016) <doi:10.1590/0103-9016-2015-0399>, spreading a better awareness of the potential usefulness, beauty and limitations of biostatistic.

Collection of functions to connect the structure of the data with the information on the samples. Three types of associations are covered: 1. linear model of principal components. 2. hierarchical clustering analysis. 3. distribution of features-sample annotation associations. Additionally, the inter-relation between sample annotations can be analyzed. Simple methods are provided for the correction of batch effects and removal of principal components.

Estimation of various biodiversity indices and related (dis)similarity measures based on individual-based (abundance) data or sampling-unit-based (incidence) data taken from one or multiple communities/assemblages.

Allows fitting of step-functions to univariate serial data where neither the number of jumps nor their positions is known by implementing the multiscale regression estimators SMUCE, simulataneous multiscale changepoint estimator, (K. Frick, A. Munk and H. Sieling, 2014) <doi:10.1111/rssb.12047> and HSMUCE, heterogeneous SMUCE, (F. Pein, H. Sieling and A. Munk, 2017) <doi:10.1111/rssb.12202>. In addition, confidence intervals for the change-point locations and bands for the unknown signal can be obtained.

Exploratory analysis on any input data describing the structure and the relationships present in the data. The package automatically select the variable and does related descriptive statistics. Analyzing information value, weight of evidence, custom tables, summary statistics, graphical techniques will be performed for both numeric and categorical predictors.