Implementation of the SIMEX-Algorithm by Cook & Stefanski (1994) <doi:10.1080/01621459.1994.10476871> and MCSIMEX by Küchenhoff, Mwalili & Lesaffre (2006) <doi:10.1111/j.1541-0420.2005.00396.x>.

The SAWNUTI algorithm performs sequence comparison for finite sequences of discrete events with non-uniform time intervals. Further description of the algorithm can be found in the paper: A. Murph, A. Flynt, B. R. King (2021). Comparing finite sequences of discrete events with non-uniform time intervals, Sequential Analysis, 40(3), 291-313. <doi:10.1080/07474946.2021.1940491>.

Collect your data on digital marketing campaigns from Snapchat Ads using the Windsor.ai API <https://windsor.ai/api-fields/>.

Generate continuous (normal, non-normal, or mixture distributions), binary, ordinal, and count (regular or zero-inflated, Poisson or Negative Binomial) variables with a specified correlation matrix, or one continuous variable with a mixture distribution. This package can be used to simulate data sets that mimic real-world clinical or genetic data sets (i.e., plasmodes, as in Vaughan et al., 2009 <DOI:10.1016/j.csda.2008.02.032>). The methods extend those found in the SimMultiCorrData R package. Standard normal variables with an imposed intermediate correlation matrix are transformed to generate the desired distributions. Continuous variables are simulated using either Fleishman (1978)'s third order <DOI:10.1007/BF02293811> or Headrick (2002)'s fifth order <DOI:10.1016/S0167-9473(02)00072-5> polynomial transformation method (the power method transformation, PMT). Non-mixture distributions require the user to specify mean, variance, skewness, standardized kurtosis, and standardized fifth and sixth cumulants. Mixture distributions require these inputs for the component distributions plus the mixing probabilities. Simulation occurs at the component level for continuous mixture distributions. The target correlation matrix is specified in terms of correlations with components of continuous mixture variables. These components are transformed into the desired mixture variables using random multinomial variables based on the mixing probabilities. However, the package provides functions to approximate expected correlations with continuous mixture variables given target correlations with the components. Binary and ordinal variables are simulated using a modification of ordsample() in package GenOrd'. Count variables are simulated using the inverse CDF method. There are two simulation pathways which calculate intermediate correlations involving count variables differently. Correlation Method 1 adapts Yahav and Shmueli's 2012 method <DOI:10.1002/asmb.901> and performs best with large count variable means and positive correlations or small means and negative correlations. Correlation Method 2 adapts Barbiero and Ferrari's 2015 modification of the GenOrd package <DOI:10.1002/asmb.2072> and performs best under the opposite scenarios. The optional error loop may be used to improve the accuracy of the final correlation matrix. The package also contains functions to calculate the standardized cumulants of continuous mixture distributions, check parameter inputs, calculate feasible correlation boundaries, and summarize and plot simulated variables.

Convenient tools for exchanging files securely from within R. By encrypting the content safe passage of files (shipment) can be provided by common but insecure carriers such as ftp and email. Based on asymmetric cryptography no management of shared secrets is needed to make a secure shipment as long as authentic public keys are available. Public keys used for secure shipments may also be obtained from external providers as part of the overall process. Transportation of files will require that relevant services such as ftp and email servers are available.

Allows TailwindCSS to be used in Shiny apps with just-in-time compiling, custom css with @apply directive, and custom tailwind configurations.

Plots a QQ-Norm Plot with several Gaussian simulations.

This package provides a graphical user interface (GUI) for fitting Bayesian regression models using the package brms which in turn relies on Stan (<https://mc-stan.org/>). The shinybrms GUI is a shiny app.

This package provides a tool for producing synthetic versions of microdata containing confidential information so that they are safe to be released to users for exploratory analysis. The key objective of generating synthetic data is to replace sensitive original values with synthetic ones causing minimal distortion of the statistical information contained in the data set. Variables, which can be categorical or continuous, are synthesised one-by-one using sequential modelling. Replacements are generated by drawing from conditional distributions fitted to the original data using parametric or classification and regression trees models. Data are synthesised via the function syn() which can be largely automated, if default settings are used, or with methods defined by the user. Optional parameters can be used to influence the disclosure risk and the analytical quality of the synthesised data. For a description of the implemented method see Nowok, Raab and Dibben (2016) <doi:10.18637/jss.v074.i11>. Functions to assess identity and attribute disclosure for the original and for the synthetic data are included in the package, and their use is illustrated in a vignette on disclosure (Practical Privacy Metrics for Synthetic Data).

Shadow Document Object Model is a web standard that offers component style and markup encapsulation. It is a critically important piece of the Web Components story as it ensures that a component will work in any environment even if other CSS or JavaScript is at play on the page. Custom HTML tags can't be directly identified with selenium tools, because Selenium doesn't provide any way to deal with shadow elements. Using this plugin you can handle any custom HTML tags.

This package provides tools for conditional and spatially dependent density estimation using Spatial Logistic Gaussian Processes (SLGPs). The approach represents probability densities through finite-rank Gaussian process priors transformed via a spatial logistic density transformation, enabling flexible non-parametric modeling of heterogeneous data. Functionality includes density prediction, quantile and moment estimation, sampling methods, and preprocessing routines for basis functions. Applications arise in spatial statistics, machine learning, and uncertainty quantification. The methodology builds on the framework of Leonard (1978) <doi:10.1111/j.2517-6161.1978.tb01655.x>, Lenk (1988) <doi:10.1080/01621459.1988.10478625>, Tokdar (2007) <doi:10.1198/106186007X210206>, Tokdar (2010) <doi:10.1214/10-BA605>, and is further aligned with recent developments in Bayesian non-parametric modelling: see Gautier (2023) <https://boristheses.unibe.ch/4377/>, and Gautier (2025) <doi:10.48550/arXiv.2110.02876>).

This package provides interface to sparsepp - fast, memory efficient hash map. It is derived from Google's excellent sparsehash implementation. We believe sparsepp provides an unparalleled combination of performance and memory usage, and will outperform your compiler's unordered_map on both counts. Only Google's dense_hash_map is consistently faster, at the cost of much greater memory usage (especially when the final size of the map is not known in advance).

Discovers synergistic gene pairs in single-cell RNA-seq and spatial transcriptomics data. Unlike conventional pairwise co-expression analyses that rely on a single correlation metric, scPairs integrates 14 complementary metrics across five orthogonal evidence layers to compute a composite synergy score with optional permutation-based significance testing. The five evidence layers span cell-level co-expression (Pearson, Spearman, biweight midcorrelation, mutual information, ratio consistency), neighbourhood-aware smoothing (KNN-smoothed correlation, neighbourhood co-expression, cluster pseudo-bulk, cross-cell-type, neighbourhood synergy), prior biological knowledge (GO/KEGG co-annotation Jaccard, pathway bridge score), trans-cellular interaction, and spatial co-variation (Lee's L, co-location quotient). This multi-scale design enables researchers to move beyond simple co-expression towards a comprehensive characterisation of cooperative gene regulation at transcriptomic and spatial resolution. For more information, see the package documentation at <https://github.com/zhaoqing-wang/scPairs>.

This package provides a spectral framework to map quantitative trait loci (QTLs) affecting joint differential networks of gene co-Expression. Test the equivalence among multiple biological networks via spectral statistics. See reference Hu, J., Weber, J. N., Fuess, L. E., Steinel, N. C., Bolnick, D. I., & Wang, M. (2025) <doi:10.1371/journal.pcbi.1012953>.

This package provides function to apply "Subgroup Identification based on Differential Effect Search" (SIDES) method proposed by Lipkovich et al. (2011) <doi:10.1002/sim.4289>.

We designed this package to provide several functions for area level of small area estimation using hierarchical Bayesian (HB) method. This package provides model using panel data for variable interest.This package also provides a dataset produced by a data generation. The rjags package is employed to obtain parameter estimates. Model-based estimators involves the HB estimators which include the mean and the variation of mean. For the reference, see Rao and Molina (2015).

Transforms or simulates data with a target empirical covariance matrix supplied by the user. The method to obtain the data with the target empirical covariance matrix is described in Section 5.1 of Christidis, Van Aelst and Zamar (2019) <arXiv:1812.05678>.

This package provides a framework for modeling cellular metabolic states and continuous metabolic trajectories from single-cell RNA-seq data using pathway-level scoring. Enables lineage-restricted metabolic analysis, metabolic pseudotime inference, module-level trend analysis, and visualization of metabolic state transitions.

This package provides tools for setting up ("design"), conducting, and evaluating large-scale simulation studies with graphics and tables, including parallel computations.

Data Sets for Kumar and Petersen (2012). Statistical Methods in Customer Relationship Management, Wiley: New York.

When working across multiple machines and, similarly for reproducible research, it can be time consuming to ensure that you have all of the needed packages installed and loaded and that the correct working directory is set. simpleSetup provides simple functions for making these tasks more straightforward.

This package creates simulated data from structural equation models with standardized loading. Data generation methods are described in Schneider (2013) <doi:10.1177/0734282913478046>.

The sdrt() function is designed for estimating subspaces for Sufficient Dimension Reduction (SDR) in time series, with a specific focus on the Time Series Central Mean subspace (TS-CMS). The package employs the Fourier transformation method proposed by Samadi and De Alwis (2023) <doi:10.48550/arXiv.2312.02110> and the Nadaraya-Watson kernel smoother method proposed by Park et al. (2009) <doi:10.1198/jcgs.2009.08076> for estimating the TS-CMS. The package provides tools for estimating distances between subspaces and includes functions for selecting model parameters using the Fourier transformation method.

Randomization of presence/absence species distribution raster data with or without including spatial structure for calculating standardized effect sizes and testing null hypothesis. The randomization algorithms are based on classical algorithms for matrices (Gotelli 2000, <doi:10.2307/177478>) implemented for raster data.