This package provides a collection of functions for statistical and multivariate analysis of surface-related data, with a focus on antimicrobial activity and omniphobicity. Designed to support materials scientists and researchers in exploring structureâ function relationships in surface-engineered materials through reproducible and interpretable workflows. For more details, see Li et al. (2021) <doi:10.1002/advs.202100368>, and Kwon et al. (2020) <doi:10.3390/polym12081826>.

High level management of widgets, windows and other graphical resources.

Takes a list of character strings and forms an adjacency matrix for the times the specified characters appear together in the strings provided. For use in social network analysis and data wrangling. Simple package, comprised of three functions.

This package performs estimation and inference on a partially missing target outcome (e.g. gene expression in an inaccessible tissue) while borrowing information from a correlated surrogate outcome (e.g. gene expression in an accessible tissue). Rather than regarding the surrogate outcome as a proxy for the target outcome, this package jointly models the target and surrogate outcomes within a bivariate regression framework. Unobserved values of either outcome are treated as missing data. In contrast to imputation-based inference, no assumptions are required regarding the relationship between the target and surrogate outcomes. Estimation in the presence of bilateral outcome missingness is performed via an expectation conditional maximization either algorithm. In the case of unilateral target missingness, estimation is performed using an accelerated least squares procedure. A flexible association test is provided for evaluating hypotheses about the target regression parameters. For additional details, see: McCaw ZR, Gaynor SM, Sun R, Lin X: "Leveraging a surrogate outcome to improve inference on a partially missing target outcome" <doi:10.1111/biom.13629>.

This package provides a simulation-based tool made to help researchers to become familiar with multilevel variations, and to build up sampling designs for their study. This tool has two main objectives: First, it provides an educational tool useful for students, teachers and researchers who want to learn to use mixed-effects models. Users can experience how the mixed-effects model framework can be used to understand distinct biological phenomena by interactively exploring simulated multilevel data. Second, it offers research opportunities to those who are already familiar with mixed-effects models, as it enables the generation of data sets that users may download and use for a range of simulation-based statistical analyses such as power and sensitivity analysis of multilevel and multivariate data [Allegue, H., Araya-Ajoy, Y.G., Dingemanse, N.J., Dochtermann N.A., Garamszegi, L.Z., Nakagawa, S., Reale, D., Schielzeth, H. and Westneat, D.F. (2016) <doi: 10.1111/2041-210X.12659>].

This package provides methods for inference using stacked multiple imputations augmented with weights. The vignette provides example R code for implementation in general multiple imputation settings. For additional details about the estimation algorithm, we refer the reader to Beesley, Lauren J and Taylor, Jeremy M G (2020) â A stacked approach for chained equations multiple imputation incorporating the substantive modelâ <doi:10.1111/biom.13372>, and Beesley, Lauren J and Taylor, Jeremy M G (2021) â Accounting for not-at-random missingness through imputation stackingâ <arXiv:2101.07954>.

The function generates and plots random snowflakes. Each snowflake is defined by a given diameter, width of the crystal, color, and random seed. Snowflakes are plotted in such way that they always remain round, no matter what the aspect ratio of the plot is. Snowflakes can be created using transparent colors, which creates a more interesting, somewhat realistic, image. Images of the snowflakes can be separately saved as svg files and used in websites as static or animated images.

This package provides a set of functions to quantify and visualise social autocorrelation.

Model stacking is an ensemble technique that involves training a model to combine the outputs of many diverse statistical models, and has been shown to improve predictive performance in a variety of settings. stacks implements a grammar for tidymodels'-aligned model stacking.

Semantic Versions allow for standardized management versions. This package implements semantic versioning handling in R. using R6 to create a mutable object that can handle deciphering and checking versions.

Hyvärinen's score matching (Hyvärinen, 2005) <https://jmlr.org/papers/v6/hyvarinen05a.html> is a useful estimation technique when the normalising constant for a probability distribution is difficult to compute. This package implements score matching estimators using automatic differentiation in the CppAD library <https://github.com/coin-or/CppAD> and is designed for quickly implementing score matching estimators for new models. Also available is general robustification (Windham, 1995) <https://www.jstor.org/stable/2346159>. Already in the package are estimators for directional distributions (Mardia, Kent and Laha, 2016) <doi:10.48550/arXiv.1604.08470> and the flexible Polynomially-Tilted Pairwise Interaction model for compositional data. The latter estimators perform well when there are zeros in the compositions (Scealy and Wood, 2023) <doi:10.1080/01621459.2021.2016422>, even many zeros (Scealy, Hingee, Kent, and Wood, 2024) <doi:10.1007/s11222-024-10412-w>. A partial interface to CppAD's ADFun objects is also available.

This package provides a set of functions is provided for 1) the stratum lengths analysis along a chosen direction, 2) fast estimation of continuous lag spatial Markov chains model parameters and probability computing (also for large data sets), 3) transition probability maps and transiograms drawing, 4) simulation methods for categorical random fields. More details on the methodology are discussed in Sartore (2013) <doi:10.32614/RJ-2013-022> and Sartore et al. (2016) <doi:10.1016/j.cageo.2016.06.001>.

Import, plot, and diagnose results from statistical catch-at-age models, used in fisheries stock assessment.

Estimates area and subarea level proportions using the Small Area Estimation (SAE) Twofold Subarea Model with a hierarchical Bayesian (HB) approach under Beta distribution. A number of simulated datasets generated for illustration purposes are also included. The rstan package is employed to estimate parameters via the Hamiltonian Monte Carlo and No U-Turn Sampler algorithm. The model-based estimators include the HB mean, the variation of the mean, and quantiles. For references, see Rao and Molina (2015) <doi:10.1002/9781118735855>, Torabi and Rao (2014) <doi:10.1016/j.jmva.2014.02.001>, Leyla Mohadjer et al.(2007) <http://www.asasrms.org/Proceedings/y2007/Files/JSM2007-000559.pdf>, Erciulescu et al.(2019) <doi:10.1111/rssa.12390>, and Yudasena (2024).

The function SurvRegCens() of this package allows estimation of a Weibull Regression for a right-censored endpoint, one interval-censored covariate, and an arbitrary number of non-censored covariates. Additional functions allow to switch between different parametrizations of Weibull regression used by different R functions, inference for the mean difference of two arbitrarily censored Normal samples, and estimation of canonical parameters from censored samples for several distributional assumptions. Hubeaux, S. and Rufibach, K. (2014) <doi:10.48550/arXiv.1402.0432>.

The goal of snpsettest is to provide simple tools that perform set-based association tests (e.g., gene-based association tests) using GWAS (genome-wide association study) summary statistics. A set-based association test in this package is based on the statistical model described in VEGAS (versatile gene-based association study), which combines the effects of a set of SNPs accounting for linkage disequilibrium between markers. This package uses a different approach from the original VEGAS implementation to compute set-level p values more efficiently, as described in <https://github.com/HimesGroup/snpsettest/wiki/Statistical-test-in-snpsettest>.

This package implements self-organising maps combined with hierarchical cluster analysis (SOM-HCA) for clustering and visualization of high-dimensional data. The package includes functions to estimate the optimal map size based on various quality measures and to generate a model using the selected dimensions. It also performs hierarchical clustering on the map nodes to group similar units. Documentation about the SOM-HCA method is provided in Pastorelli et al. (2024) <doi:10.1002/xrs.3388>.

This data package contains four datasets of quantitative PCR (qPCR) amplification curves that were used as supplementary data in the research article by Sisti et al. (2010), <doi:10.1186/1471-2105-11-186>. The primary dataset comprises a ten-fold dilution series spanning copy numbers from 3.14 Ã 10^7 to 3.14 Ã 10^2, with twelve replicates per concentration. These samples are based on a pGEM-T Promega plasmid containing a 104 bp fragment of the mitochondrial gene NADH dehydrogenase 1 (MT-ND1), amplified using the ND1/ND2 primer pair. The remaining three datasets contain qPCR results in the presence of specific PCR inhibitors: tannic acid, immunoglobulin G (IgG), and quercetin, respectively, to assess their effects on the amplification process. These datasets are useful for researchers interested in PCR kinetics. The original raw data file is available as Additional File 1: <https://static-content.springer.com/esm/art%3A10.1186%2F1471-2105-11-186/MediaObjects/12859_2009_3643_MOESM1_ESM.XLS>.

Efficient Markov chain Monte Carlo (MCMC) algorithms for fully Bayesian estimation of time-varying parameter vector autoregressive models with stochastic volatility (TVP-VAR-SV) under shrinkage priors and dynamic shrinkage processes. Details on the TVP-VAR-SV model and the shrinkage priors can be found in Cadonna et al. (2020) <doi:10.3390/econometrics8020020>, details on the software can be found in Knaus et al. (2021) <doi:10.18637/jss.v100.i13>, while details on the dynamic shrinkage process can be found in Knaus and Frühwirth-Schnatter (2023) <doi:10.48550/arXiv.2312.10487>.

An implementation of the selectboost algorithm (Bertrand et al. 2020, Bioinformatics', <doi:10.1093/bioinformatics/btaa855>), which is a general algorithm that improves the precision of any existing variable selection method. This algorithm is based on highly intensive simulations and takes into account the correlation structure of the data. It can either produce a confidence index for variable selection or it can be used in an experimental design planning perspective.

This package provides tools for setting up ("design"), conducting, and evaluating large-scale simulation studies with graphics and tables, including parallel computations.

An implementation of the surrogate approach to residuals and diagnostics for ordinal and general regression models; for details, see Liu and Zhang (2017) <doi:10.1080/01621459.2017.1292915>. These residuals can be used to construct standard residual plots for model diagnostics (e.g., residual-vs-fitted value plots, residual-vs-covariate plots, Q-Q plots, etc.). The package also provides an autoplot function for producing standard diagnostic plots using ggplot2 graphics. The package currently supports cumulative link models from packages MASS', ordinal', rms', and VGAM'. Support for binary regression models using the standard glm function is also available.

This package implements methods for variable selection in linear regression based on the "Sum of Single Effects" (SuSiE) model, as described in Wang et al (2020) <DOI:10.1101/501114> and Zou et al (2021) <DOI:10.1101/2021.11.03.467167>. These methods provide simple summaries, called "Credible Sets", for accurately quantifying uncertainty in which variables should be selected. The methods are motivated by genetic fine-mapping applications, and are particularly well-suited to settings where variables are highly correlated and detectable effects are sparse. The fitting algorithm, a Bayesian analogue of stepwise selection methods called "Iterative Bayesian Stepwise Selection" (IBSS), is simple and fast, allowing the SuSiE model be fit to large data sets (thousands of samples and hundreds of thousands of variables).

Symbolic data analysis methods: importing/exporting data from ASSO XML Files, distance calculation for symbolic data (Ichino-Yaguchi, de Carvalho measure), zoom star plot, 3d interval plot, multidimensional scaling for symbolic interval data, dynamic clustering based on distance matrix, HINoV method for symbolic data, Ichino's feature selection method, principal component analysis for symbolic interval data, decision trees for symbolic data based on optimal split with bagging, boosting and random forest approach (+visualization), kernel discriminant analysis for symbolic data, Kohonen's self-organizing maps for symbolic data, replication and profiling, artificial symbolic data generation. (Milligan, G.W., Cooper, M.C. (1985) <doi:10.1007/BF02294245>, Breiman, L. (1996), <doi:10.1007/BF00058655>, Hubert, L., Arabie, P. (1985), <doi:10.1007%2FBF01908075>, Ichino, M., & Yaguchi, H. (1994), <doi:10.1109/21.286391>, Rand, W.M. (1971) <doi:10.1080/01621459.1971.10482356>, Breckenridge, J.N. (2000) <doi:10.1207/S15327906MBR3502_5>, Groenen, P.J.F, Winsberg, S., Rodriguez, O., Diday, E. (2006) <doi:10.1016/j.csda.2006.04.003>, Dudek, A. (2007), <doi:10.1007/978-3-540-70981-7_4>).