This package implements the exponential Factor Copula Model (eFCM) of Castro-Camilo, D. and Huser, R. (2020) for spatial extremes, with tools for dependence estimation, tail inference, and visualization. The package supports likelihood-based inference, Gaussian process modeling via Matérn covariance functions, and bootstrap uncertainty quantification. See Castro-Camilo and Huser (2020) <doi:10.1080/01621459.2019.1647842>.
When fitting a set of linear regressions which have some same variables, we can separate the matrix and reduce the computation cost. This package aims to fit a set of repeated linear regressions faster. More details can be found in this blog Lijun Wang (2017) <https://stats.hohoweiya.xyz/regression/2017/09/26/An-R-Package-Fit-Repeated-Linear-Regressions/>.
Computes and tests individual (species, phylogenetic and functional) diversity-area relationships, i.e., how species-, phylogenetic- and functional-diversity varies with spatial scale around the individuals of some species in a community. See applications of these methods in Wiegand et al. (2007) <doi:10.1073/pnas.0705621104> or Chacon-Labella et al. (2016) <doi:10.1007/s00442-016-3547-z>.
An implementation of generalized linear models (GLMs) for studying relationships among attributes in connected populations, where responses of connected units can be dependent, as introduced by Fritz et al. (2025) <doi:10.1080/01621459.2025.2565851>. igml extends GLMs for independent responses to dependent responses and can be used for studying spillover in connected populations and other network-mediated phenomena.
This package implements a Gibbs sampler to do linear regression with multiple covariates, multiple responses, Gaussian measurement errors on covariates and responses, Gaussian intrinsic scatter, and a covariate prior distribution which is given by either a Gaussian mixture of specified size or a Dirichlet process with a Gaussian base distribution. Described further in Mantz (2016) <DOI:10.1093/mnras/stv3008>.
Share R objects across processes on the same machine via a single copy in POSIX shared memory (Linux, macOS) or a Win32 file mapping (Windows). Every process reads from the same physical pages through the R Alternative Representation ('ALTREP') framework, giving lazy, zero-copy access. Shared objects serialize compactly as their shared memory name rather than their full contents.
Helpers for common data analysis tasks including missing-value summaries and filters, simple reporting and plotting utilities, Excel import and export workflows, and reading geospatial formats (for example shapefiles in zip archives, file geodatabases, KMZ, and KML) via sf and related packages. Also includes small project utilities such as creating directories, gitignore scaffolding, combined package loading, and optional lintr setup.
This package provides functions and wrappers for using the Multiple Aggregation Prediction Algorithm (MAPA) for time series forecasting. MAPA models and forecasts time series at multiple temporal aggregation levels, thus strengthening and attenuating the various time series components for better holistic estimation of its structure. For details see Kourentzes et al. (2014) <doi:10.1016/j.ijforecast.2013.09.006>.
Nonparametric test of independence between a pair of spatial objects (random fields, point processes) based on random shifts with torus or variance correction. See MrkviÄ ka et al. (2021) <doi:10.1016/j.spasta.2020.100430>, DvoŠák et al. (2022) <doi:10.1111/insr.12503>, DvoŠák and MrkviÄ ka (2024) <doi:10.1080/10618600.2024.2357626>.
Analyse common types of plant phenotyping data, provide a simplified interface to longitudinal growth modeling and select Bayesian statistics, and streamline use of PlantCV output. Several Bayesian methods and reporting guidelines for Bayesian methods are described in Kruschke (2018) <doi:10.1177/2515245918771304>, Kruschke (2013) <doi:10.1037/a0029146>, and Kruschke (2021) <doi:10.1038/s41562-021-01177-7>.
This package implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.
Seven different methods for multiple testing problems. The SGoF-type methods (see for example, Carvajal Rodrà guez et al., 2009 <doi:10.1186/1471-2105-10-209>; de Uña à lvarez, 2012 <doi:10.1515/1544-6115.1812>; Castro Conde et al., 2015 <doi:10.1177/0962280215597580>) and the BH and BY false discovery rate controlling procedures.
This package provides functions for implementing the targeted gold standard (GS) testing. You provide the true disease or treatment failure status and the risk score, tell TGST the availability of GS tests and which method to use, and it returns the optimal tripartite rules. Please refer to Liu et al. (2013) <doi:10.1080/01621459.2013.810149> for more details.
The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but tcpl can be used to support diverse chemical screening efforts.
Population genetic data such as Single Nucleotide Polymorphisms (SNPs) is often used to identify genomic regions that have been under recent natural or artificial selection and might provide clues about the molecular mechanisms of adaptation. One approach, the concept of an Extended Haplotype Homozygosity (EHH), introduced by (Sabeti 2002) <doi:10.1038/nature01140>, has given rise to several statistics designed for whole genome scans. The package provides functions to compute three of these, namely: iHS (Voight 2006) <doi:10.1371/journal.pbio.0040072> for detecting positive or Darwinian selection within a single population as well as Rsb (Tang 2007) <doi:10.1371/journal.pbio.0050171> and XP-EHH (Sabeti 2007) <doi:10.1038/nature06250>, targeted at differential selection between two populations. Various plotting functions are included to facilitate visualization and interpretation of these statistics.
The Recode library converts files between character sets and usages. It recognises or produces over 200 different character sets (or about 300 if combined with an iconv library) and transliterates files between almost any pair. When exact transliteration are not possible, it gets rid of offending characters or falls back on approximations. The recode program is a handy front-end to the library.
Defining the identity of a cell is fundamental to understand the heterogeneity of cells to various environmental signals and perturbations. We present Cepo, a new method to explore cell identities from single-cell RNA-sequencing data using differential stability as a new metric to define cell identity genes. Cepo computes cell-type specific gene statistics pertaining to differential stable gene expression.
The package provides S4 classes and methods to filter, summarise and visualise genetic variation data stored in VCF files. In particular, the package extends the FilterRules class (S4Vectors package) to define news classes of filter rules applicable to the various slots of VCF objects. Functionalities are integrated and demonstrated in a Shiny web-application, the Shiny Variant Explorer (tSVE).
Target capture experiments combine hybridization-based (in solution or on microarrays) capture and enrichment of genomic regions of interest (e.g. the exome) with high throughput sequencing of the captured DNA fragments. This package provides functionalities for assessing and visualizing the quality of the target enrichment process, like specificity and sensitivity of the capture, per-target read coverage and so on.
This package provides functions provide risk projections of invasive breast cancer based on Gail model according to National Cancer Institute's Breast Cancer Risk Assessment Tool algorithm for specified race/ethnic groups and age intervals. Gail MH, Brinton LA, et al (1989) <doi:10.1093/jnci/81.24.1879>. Marthew PB, Gail MH, et al (2016) <doi:10.1093/jnci/djw215>.
We use a Bayesian approach to run individual patient data meta-analysis and network meta-analysis using JAGS'. The methods incorporate shrinkage methods and calculate patient-specific treatment effects as described in Seo et al. (2021) <DOI:10.1002/sim.8859>. This package also includes user-friendly functions that impute missing data in an individual patient data using mice-related packages.
This package provides tools to help the design and analysis of resilient non-inferiority trials. These include functions for sample size calculations and analyses of trials, with either a risk difference, risk ratio or arc-sine difference margin, and a function to run simulations to design a trial with the methods described in Quartagno et al. (2019) <arXiv:1905.00241>.
If translate English or Chinese sentence, there is a faster way for R user. You can pass in an English or Chinese sentence, ecce package support both English and Chinese translation. It also support browse translation results in website. In addition, also support obtain the pinyin of the Chinese character, you can more easily understand the pronunciation of the Chinese character.
This package provides Generalized Inferences based on exact distributions and exact probability statements for mixed effect models, provided by such papers as Weerahandi and Yu (2020) <doi:10.1186/s40488-020-00105-w> under the widely used Compound Symmetric Covariance structure. The package returns the estimation of the coefficients in random and fixed part of the mixed models by generalized inference.