An Electronic Data Capture system (EDC) and Data Standard agnostic solution that enables the pharmaceutical programming community to develop Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM) datasets in R. The reusable algorithms concept in sdtm.oak provides a framework for modular programming and can potentially automate the conversion of raw clinical data to SDTM through standardized SDTM specifications. SDTM is one of the required standards for data submission to the Food and Drug Administration (FDA) in the United States and Pharmaceuticals and Medical Devices Agency (PMDA) in Japan. SDTM standards are implemented following the SDTM Implementation Guide as defined by CDISC <https://www.cdisc.org/standards/foundational/sdtmig>.

This package provides functions for color-based visualization of multivariate data, i.e. colorgrams or heatmaps. Lower-level functions map numeric values to colors, display a matrix as an array of colors, and draw color keys. Higher-level plotting functions generate a bivariate histogram, a dendrogram aligned with a color-coded matrix, a triangular distance matrix, and more.

Support for reading/writing simple feature ('sf') spatial objects from/to Parquet files. Parquet files are an open-source, column-oriented data storage format from Apache (<https://parquet.apache.org/>), now popular across programming languages. This implementation converts simple feature list geometries into well-known binary format for use by arrow', and coordinate reference system information is maintained in a standard metadata format.

An implementation of W3C WebDriver 2.0 (<https://w3c.github.io/webdriver/>), allowing interaction with a Selenium Server (<https://www.selenium.dev/documentation/grid/>) instance from R'. Allows a web browser to be automated from R'.

Traditional model evaluation metrics fail to capture model performance under less than ideal conditions. This package employs techniques to evaluate models "under-stress". This includes testing models extrapolation ability, or testing accuracy on specific sub-samples of the overall model space. Details describing stress-testing methods in this package are provided in Haycock (2023) <doi:10.26076/2am5-9f67>. The other primary contribution of this package is provided to R users access to the Python library PyCaret <https://pycaret.org/> for quick and easy access to auto-tuned machine learning models.

This package provides a set of tools developed at Simularia for Simularia, to help preprocessing and post-processing of meteorological and air quality data.

An implementation of sensitivity analysis for phylogenetic comparative methods. The package is an umbrella of statistical and graphical methods that estimate and report different types of uncertainty in PCM: (i) Species Sampling uncertainty (sample size; influential species and clades). (ii) Phylogenetic uncertainty (different topologies and/or branch lengths). (iii) Data uncertainty (intraspecific variation and measurement error).

This package provides a set of tools for state-dependent empirical analysis through both VAR- and local projection-based state-dependent forecasts, impulse response functions, historical decompositions, and forecast error variance decompositions.

Computes standard error and confidence interval of various descriptive statistics under various designs and sampling schemes. The main function, superb(), return a plot. It can also be used to obtain a dataframe with the statistics and their precision intervals so that other plotting environments (e.g., Excel) can be used. See Cousineau and colleagues (2021) <doi:10.1177/25152459211035109> or Cousineau (2017) <doi:10.5709/acp-0214-z> for a review as well as Cousineau (2005) <doi:10.20982/tqmp.01.1.p042>, Morey (2008) <doi:10.20982/tqmp.04.2.p061>, Baguley (2012) <doi:10.3758/s13428-011-0123-7>, Cousineau & Laurencelle (2016) <doi:10.1037/met0000055>, Cousineau & O'Brien (2014) <doi:10.3758/s13428-013-0441-z>, Calderini & Harding <doi:10.20982/tqmp.15.1.p001> for specific references. The documentation is available at <https://dcousin3.github.io/superb/> .

This package implements data-driven identification methods for structural vector autoregressive (SVAR) models as described in Lange et al. (2021) <doi:10.18637/jss.v097.i05>. Based on an existing VAR model object (provided by e.g. VAR() from the vars package), the structural impact matrix is obtained via data-driven identification techniques (i.e. changes in volatility (Rigobon, R. (2003) <doi:10.1162/003465303772815727>), patterns of GARCH (Normadin, M., Phaneuf, L. (2004) <doi:10.1016/j.jmoneco.2003.11.002>), independent component analysis (Matteson, D. S, Tsay, R. S., (2013) <doi:10.1080/01621459.2016.1150851>), least dependent innovations (Herwartz, H., Ploedt, M., (2016) <doi:10.1016/j.jimonfin.2015.11.001>), smooth transition in variances (Luetkepohl, H., Netsunajev, A. (2017) <doi:10.1016/j.jedc.2017.09.001>) or non-Gaussian maximum likelihood (Lanne, M., Meitz, M., Saikkonen, P. (2017) <doi:10.1016/j.jeconom.2016.06.002>)).

This package performs estimation and inference on a partially missing target outcome (e.g. gene expression in an inaccessible tissue) while borrowing information from a correlated surrogate outcome (e.g. gene expression in an accessible tissue). Rather than regarding the surrogate outcome as a proxy for the target outcome, this package jointly models the target and surrogate outcomes within a bivariate regression framework. Unobserved values of either outcome are treated as missing data. In contrast to imputation-based inference, no assumptions are required regarding the relationship between the target and surrogate outcomes. Estimation in the presence of bilateral outcome missingness is performed via an expectation conditional maximization either algorithm. In the case of unilateral target missingness, estimation is performed using an accelerated least squares procedure. A flexible association test is provided for evaluating hypotheses about the target regression parameters. For additional details, see: McCaw ZR, Gaynor SM, Sun R, Lin X: "Leveraging a surrogate outcome to improve inference on a partially missing target outcome" <doi:10.1111/biom.13629>.

This package provides a simple interface to integrate star ratings into your shiny apps. It can be used for customer feedback systems, user reviews, or any application that requires user ratings. shinyRatings offers a straightforward and customisable solution that enhances user engagement and facilitates valuable feedback collection.

Simple SendGrid Email API client for creating and sending emails. For more information, visit the official SendGrid Email API documentation: <https://sendgrid.com/en-us/solutions/email-api>.

Implementation of single-source capture-recapture methods for population size estimation using zero-truncated, zero-one truncated and zero-truncated one-inflated Poisson, Geometric and Negative Binomial regression as well as Zelterman's and Chao's regression. Package includes point and interval estimators for the population size with variances estimated using analytical or bootstrap method. Details can be found in: van der Heijden et all. (2003) <doi:10.1191/1471082X03st057oa>, Böhning and van der Heijden (2019) <doi:10.1214/18-AOAS1232>, Böhning et al. (2020) Capture-Recapture Methods for the Social and Medical Sciences or Böhning and Friedl (2021) <doi:10.1007/s10260-021-00556-8>.

Simulate genotypes in SNP (single nucleotide polymorphisms) Matrix as random numbers from an uniform distribution, for diploid organisms (coded by 0, 1, 2), Sikorska et al., (2013) <doi:10.1186/1471-2105-14-166>, or half-sib/full-sib SNP matrix from real or simulated parents SNP data, assuming mendelian segregation. Simulate phenotypic traits for real or simulated SNP data, controlled by a specific number of quantitative trait loci and their effects, sampled from a Normal or an Uniform distributions, assuming a pure additive model. This is useful for testing association and genomic prediction models or for educational purposes.

Created for population health analytics and monitoring. The functions in this package work best when working with patient level Master Patient Index-like datasets . Built to be used by NHS bodies and other health service providers.

Processing and analysis of field collected or simulated sprinkler system catch data (depths) to characterize irrigation uniformity and efficiency using standard and other measures. Standard measures include the Christiansen coefficient of uniformity (CU) as found in Christiansen, J.E.(1942, ISBN:0138779295, "Irrigation by Sprinkling"); and distribution uniformity (DU), potential efficiency of the low quarter (PELQ), and application efficiency of the low quarter (AELQ) that are implementations of measures of the same notation in Keller, J. and Merriam, J.L. (1978) "Farm Irrigation System Evaluation: A Guide for Management" <https://pdf.usaid.gov/pdf_docs/PNAAG745.pdf>. spreval::DU.lh is similar to spreval::DU but is the distribution uniformity of the low half instead of low quarter as in DU. spreval::PELQT is a version of spreval::PELQ adapted for traveling systems instead of lateral move or solid-set sprinkler systems. The function spreval::eff is analogous to the method used to compute application efficiency for furrow irrigation presented in Walker, W. and Skogerboe, G.V. (1987,ISBN:0138779295, "Surface Irrigation: Theory and Practice"),that uses piecewise integration of infiltrated depth compared against soil-moisture deficit (SMD), when the argument "target" is set equal to SMD. The other functions contained in the package provide graphical representation of sprinkler system uniformity, and other standard univariate parametric and non-parametric statistical measures as applied to sprinkler system catch depths. A sample data set of field test data spreval::catchcan (catch depths) is provided and is used in examples and vignettes. Agricultural systems emphasized, but this package can be used for landscape irrigation evaluation, and a landscape (turf) vignette is included as an example application.

Determines networks of significant synchronization between the discrete states of nodes; see Tumminello et al <doi:10.1371/journal.pone.0017994>.

This package provides a critical first step in systematic literature reviews and mining of academic texts is to identify relevant texts from a range of sources, particularly databases such as Web of Science or Scopus'. These databases often export in different formats or with different metadata tags. synthesisr expands on the tools outlined by Westgate (2019) <doi:10.1002/jrsm.1374> to import bibliographic data from a range of formats (such as bibtex', ris', or ciw') in a standard way, and allows merging and deduplication of the resulting dataset.

This package provides functions for efficiently estimating properties of the Van Genuchten-Mualem model for soil hydraulic parameters from possibly sparse soil water retention and hydraulic conductivity data by multi-response parameter estimation methods (Stewart, W.E., Caracotsios, M. Soerensen, J.P. (1992) "Parameter estimation from multi-response data" <doi:10.1002/aic.690380502>). Parameter estimation is simplified by exploiting the fact that residual and saturated water contents and saturated conductivity are conditionally linear parameters (Bates, D. M. and Watts, D. G. (1988) "Nonlinear Regression Analysis and Its Applications" <doi:10.1002/9780470316757>). Estimated parameters are optionally constrained by the evaporation characteristic length (Lehmann, P., Bickel, S., Wei, Z. and Or, D. (2020) "Physical Constraints for Improved Soil Hydraulic Parameter Estimation by Pedotransfer Functions" <doi:10.1029/2019WR025963>) to ensure that the estimated parameters are physically valid. Common S3 methods and further utility functions allow to process, explore and visualise estimation results.

Fits single-species (univariate) and multi-species (multivariate) non-spatial and spatial abundance models in a Bayesian framework using Markov Chain Monte Carlo (MCMC). Spatial models are fit using Nearest Neighbor Gaussian Processes (NNGPs). Details on NNGP models are given in Datta, Banerjee, Finley, and Gelfand (2016) <doi:10.1080/01621459.2015.1044091> and Finley, Datta, and Banerjee (2022) <doi:10.18637/jss.v103.i05>. Fits single-species and multi-species spatial and non-spatial versions of generalized linear mixed models (Gaussian, Poisson, Negative Binomial), N-mixture models (Royle 2004 <doi:10.1111/j.0006-341X.2004.00142.x>) and hierarchical distance sampling models (Royle, Dawson, Bates (2004) <doi:10.1890/03-3127>). Multi-species spatial models are fit using a spatial factor modeling approach with NNGPs for computational efficiency.

Makes it possible to serve map tiles for web maps (e.g. leaflet) based on a function or a stars object without having to render them in advance. This enables parallelization of the rendering, separating the data source and visualization location and to provide web services.

Ratings, votes, swear words and sentiments are analysed for the show SouthPark through a Shiny application after web scraping from IMDB and the website <https://southpark.fandom.com/wiki/South_Park_Archives>.

Pathway Analysis is statistically linking observations on the molecular level to biological processes or pathways on the systems(i.e., organism, organ, tissue, cell) level. Traditionally, pathway analysis methods regard pathways as collections of single genes and treat all genes in a pathway as equally informative. However, this can lead to identifying spurious pathways as statistically significant since components are often shared amongst pathways. SIGORA seeks to avoid this pitfall by focusing on genes or gene pairs that are (as a combination) specific to a single pathway. In relying on such pathway gene-pair signatures (Pathway-GPS), SIGORA inherently uses the status of other genes in the experimental context to identify the most relevant pathways. The current version allows for pathway analysis of human and mouse datasets. In addition, it contains pre-computed Pathway-GPS data for pathways in the KEGG and Reactome pathway repositories and mechanisms for extracting GPS for user-supplied repositories.