This package provides utilities for conducting specification curve analyses (Simonsohn, Simmons & Nelson (2020, <doi: 10.1038/s41562-020-0912-z>) or multiverse analyses (Steegen, Tuerlinckx, Gelman & Vanpaemel, 2016, <doi: 10.1177/1745691616658637>) including functions to setup, run, evaluate, and plot all specifications.

Tree-structured modelling of categorical predictors (Tutz and Berger (2018), <doi:10.1007/s11634-017-0298-6>) or measurement units (Berger and Tutz (2018), <doi:10.1080/10618600.2017.1371030>).

Density, distribution function, quantile function and random generation for the skewed t distribution of Fernandez and Steel.

Interactive visualizations of graphs created with the igraph package using a htmlwidgets wrapper for the sigma.js network visualization v2.4.0 <https://www.sigmajs.org/>, enabling to display several thousands of nodes. While several R packages have been developed to interface sigma.js', all were developed for v1.x.x and none have migrated to v2.4.0 nor are they planning to. This package builds upon the sigmaNet package, and users familiar with it will recognize the similar design approach. Two extensions have been added to the classic sigma.js visualizations by overriding the underlying JavaScript code, enabling to draw a frame around node labels, and to display labels on multiple lines by parsing line breaks. Other additional functionalities that did not require overriding sigma.js code include toggling node visibility when clicked using a node attribute and highlighting specific edges. sigma.js is currently preparing a stable release v3.0.0, and this package plans to update to it when it is available.

Allows the user to estimate a vector logistic smooth transition autoregressive model via maximum log-likelihood or nonlinear least squares. It further permits to test for linearity in the multivariate framework against a vector logistic smooth transition autoregressive model with a single transition variable. The estimation method is discussed in Terasvirta and Yang (2014, <doi:10.1108/S0731-9053(2013)0000031008>). Also, realized covariances can be constructed from stock market prices or returns, as explained in Andersen et al. (2001, <doi:10.1016/S0304-405X(01)00055-1>).

This package provides a pipeline that can process single or multiple Single Cell RNAseq samples primarily specializes in Clustering and Dimensionality Reduction. Meanwhile we use common cell type marker genes for T cells, B cells, Myeloid cells, Epithelial cells, and stromal cells (Fiboblast, Endothelial cells, Pericyte, Smooth muscle cells) to visualize the Seurat clusters, to facilitate labeling them by biological names. Once users named each cluster, they can evaluate the quality of them again and find the de novo marker genes also.

This package provides functions for tabulating and summarizing categorical, multiple response, ordinal, and continuous variables in R data frames. Makes it easy to create clear, structured summary tables, so you spend less time wrangling data and more time interpreting it.

Spatiotemporal individual-level model of seasonal infectious disease transmission within the Susceptible-Exposed-Infectious-Recovered-Susceptible (SEIRS) framework are applied to model seasonal infectious disease transmission. This package employs a likelihood based Monte Carlo Expectation Conditional Maximization (MCECM) algorithm for estimating model parameters. In addition to model fitting and parameter estimation, the package offers functions for calculating AIC using real pandemic data and conducting simulation studies customized to user-specified model configurations.

The stress addition approach is an alternative to the traditional concentration addition or effect addition models. It allows the modelling of tri-phasic concentration-response relationships either as single toxicant experiments, in combination with an environmental stressor or as mixtures of two toxicants. See Liess et al. (2019) <doi:10.1038/s41598-019-51645-4> and Liess et al. (2020) <doi:10.1186/s12302-020-00394-7>.

It fits scale mixture of skew-normal linear mixed models using either an expectationâ maximization (EM) type algorithm or its accelerated version (Damped Anderson Acceleration with Epsilon Monotonicity, DAAREM), including some possibilities for modeling the within-subject dependence <doi:10.18637/jss.v115.i07>.

Set of functions for Stochastic Data Envelopment Analysis. Chance constrained versions of radial, directional and additive DEA models are implemented, as long as super-efficiency models. See: Cooper, W.W.; Deng, H.; Huang, Z.; Li, S.X. (2002). <doi:10.1057/palgrave.jors.2601433>, Bolós, V.J.; Benà tez, R.; Coll-Serrano, V. (2024) <doi:10.1016/j.orp.2024.100307>.

Execute files of SQL and manage database connections. SQL statements and queries may be interpolated with string literals. Execution of individual statements and queries may be controlled with keywords. Multiple connections may be defined with YAML and accessed by name.

This package implements the smooth LASSO estimator for the function-on-function linear regression model described in Centofanti et al. (2022) <doi:10.1016/j.csda.2022.107556>.

In clinical trials, endpoints are sometimes evaluated with uncertainty. Adjudication is commonly adopted to ensure the study integrity. We propose to use multiple imputation (MI) introduced by Robin (1987) <doi:10.1002/9780470316696> to incorporate these uncertainties if reasonable event probabilities were provided. The method has been applied to Cox Proportional Hazard (PH) model, Kaplan-Meier (KM) estimation and Log-rank test in this package. Moreover, weighted estimations discussed in Cook (2004) <doi:10.1016/S0197-2456(00)00053-2> were also implemented with weights calculated from event probabilities. In conclusion, this package can handle time-to-event analysis if events presented with uncertainty by different methods.

Pathway Analysis is statistically linking observations on the molecular level to biological processes or pathways on the systems(i.e., organism, organ, tissue, cell) level. Traditionally, pathway analysis methods regard pathways as collections of single genes and treat all genes in a pathway as equally informative. However, this can lead to identifying spurious pathways as statistically significant since components are often shared amongst pathways. SIGORA seeks to avoid this pitfall by focusing on genes or gene pairs that are (as a combination) specific to a single pathway. In relying on such pathway gene-pair signatures (Pathway-GPS), SIGORA inherently uses the status of other genes in the experimental context to identify the most relevant pathways. The current version allows for pathway analysis of human and mouse datasets. In addition, it contains pre-computed Pathway-GPS data for pathways in the KEGG and Reactome pathway repositories and mechanisms for extracting GPS for user-supplied repositories.

This is a shape preserving spline <doi:10.1137/0720057> which is guaranteed to be monotonic and concave or convex if the data is monotonic and concave or convex. It does not use any optimisation and is therefore quick and smoothly converges to a fixed point in economic dynamics problems including value function iteration. It also automatically gives the first two derivatives of the spline and options for determining behaviour when evaluated outside the interpolation domain.

Generates artificial point patterns marked by their spatial and temporal signatures. The resulting point cloud may exhibit inherent interactions between both signatures. The simulation integrates microsimulation (Holm, E., (2017)<doi:10.1002/9781118786352.wbieg0320>) and agent-based models (Bonabeau, E., (2002)<doi:10.1073/pnas.082080899>), beginning with the configuration of movement characteristics for the specified agents (referred to as walkers') and their interactions within the simulation environment. These interactions (Quaglietta, L. and Porto, M., (2019)<doi:10.1186/s40462-019-0154-8>) result in specific spatiotemporal patterns that can be visualized, analyzed, and used for various analytical purposes. Given the growing scarcity of detailed spatiotemporal data across many domains, this package provides an alternative data source for applications in social and life sciences.

Given independent and identically distributed observations X(1), ..., X(n) from a Generalized Pareto distribution with shape parameter gamma in [-1,0], offers several estimates to compute estimates of gamma. The estimates are based on the principle of replacing the order statistics by quantiles of a distribution function based on a log--concave density function. This procedure is justified by the fact that the GPD density is log--concave for gamma in [-1,0].

This package creates a numeric guide for writing the formula for the determinant of a square matrix (a detguide) as a function of the elements of the matrix and writes out that formula, the symbolic representation.

Computes synchrony as windowed cross-correlation based on two-dimensional time series in a text file you can upload. SUSY works as described in Tschacher & Meier (2020) <doi:10.1080/10503307.2019.1612114>.

This package provides a comprehensive statistical toolbox for National Statistics Institutes (INS) in Africa. Provides functions for survey data import ('KoboToolbox', ODK', CSPro', Excel', Stata', SPSS'), data processing and validation, weighted statistical analysis (descriptive statistics, cross-tabulations, regression, Human Development Index (HDI), Multidimensional Poverty Index (MPI) following Alkire and Foster (2011) <doi:10.1093/oep/gpr051>, inequalities), visualization (age pyramids, thematic maps, official charts) and dissemination ('SDMX export, DDI metadata, anonymization, Word/PDF reports). Designed to work in resource-constrained environments, offline and in French.

Shiny Module to create, visualize, customize and export Excel-like pivot table.

Plots that illustrate the flow of information or material.

Understand human performance from the perspective of sampling, both looking at how people generate samples and how people use the samples they have generated. A longer overview and other resources can be found at <https://sampling.warwick.ac.uk>.