The *MungeSumstats* package is designed to facilitate the standardisation of GWAS summary statistics. It reformats inputted summary statisitics to include SNP, CHR, BP and can look up these values if any are missing. It also pefrorms dozens of QC and filtering steps to ensure high data quality and minimise inter-study differences.

Function multiroc() can be used for computing and visualizing Receiver Operating Characteristics (ROC) and Area Under the Curve (AUC) for multi-class classification problems. It supports both One-vs-One approach by M.Bishop, C. (2006, ISBN:978-0-387-31073-2) and One-vs-All approach by Murphy P., K. (2012, ISBN:9780262018029).

This package provides functions are provided for calculating efficiency using multiplier DEA (Data Envelopment Analysis): Measuring the efficiency of decision making units (Charnes et al., 1978 <doi:10.1016/0377-2217(78)90138-8>) and cross efficiency using single and two-phase approach. In addition, it includes some datasets for calculating efficiency and cross efficiency.

This package provides a collection of tools for doing various analyses of multi-state QTL data, with a focus on visualization and interpretation. The package multistateQTL contains functions which can remove or impute missing data, identify significant associations, as well as categorise features into global, multi-state or unique. The analysis results are stored in a QTLExperiment object, which is based on the SummarisedExperiment framework.

This package is designed to simplify the development and distribution of scripts for theatrical musicals, especially ones under development. The output is formatted to follow generally accepted script style while also maintaining a high level of typographic integrity, and includes commands for dialog, lyrics, stage directions, music and dance cues, rehearsal marks, and more. It gracefully handles dialog that crosses page breaks, and can generate lists of songs and lists of dances in the show.

Check concordance of a vector of mutation impacts with standard dictionaries such as Sequence Ontology (SO) <http://www.sequenceontology.org/>, Mutation Annotation Format (MAF) <https://docs.gdc.cancer.gov/Encyclopedia/pages/Mutation_Annotation_Format_TCGAv2/> or Prediction and Annotation of Variant Effects (PAVE) <https://github.com/hartwigmedical/hmftools/tree/master/pave>. It enables conversion between SO/PAVE and MAF terms and selection of the most severe consequence where multiple ampersand (&) delimited impacts are given.

Matching algorithm based on network-flow structure. Users are able to modify the emphasis on three different optimization goals: two different distance measures and the number of treated units left unmatched. The method is proposed by Pimentel and Kelz (2019) <doi:10.1080/01621459.2020.1720693>. The rrelaxiv package, which provides an alternative solver for the underlying network flow problems, carries an academic license and is not available on CRAN, but may be downloaded from Github at <https://github.com/josherrickson/rrelaxiv/>.

Computing transitive (and non-transitive) index numbers (Coelli et al., 2005 <doi:10.1007/b136381>) for cross-sections and panel data. For the calculation of transitive indexes, the EKS (Coelli et al., 2005 <doi:10.1007/b136381>; Rao et al., 2002 <doi:10.1007/978-1-4615-0851-9_4>) and Minimum spanning tree (Hill, 2004 <doi:10.1257/0002828043052178>) methods are implemented. Traditional fixed-base and chained indexes, and their growth rates, can also be derived using the Paasche, Laspeyres, Fisher and Tornqvist formulas.

Meta-analyses can be compromised by studies internal biases (e.g., confounding in nonrandomized studies) as well as by publication bias. This package conducts sensitivity analyses for the joint effects of these biases (per Mathur (2022) <doi:10.31219/osf.io/u7vcb>). These sensitivity analyses address two questions: (1) For a given severity of internal bias across studies and of publication bias, how much could the results change?; and (2) For a given severity of publication bias, how severe would internal bias have to be, hypothetically, to attenuate the results to the null or by a given amount?

Distance multivariance is a measure of dependence which can be used to detect and quantify dependence of arbitrarily many random vectors. The necessary functions are implemented in this packages and examples are given. It includes: distance multivariance, distance multicorrelation, dependence structure detection, tests of independence and copula versions of distance multivariance based on the Monte Carlo empirical transform. Detailed references are given in the package description, as starting point for the theoretic background we refer to: B. Böttcher, Dependence and Dependence Structures: Estimation and Visualization Using the Unifying Concept of Distance Multivariance. Open Statistics, Vol. 1, No. 1 (2020), <doi:10.1515/stat-2020-0001>.

An implementation of a method for building simultaneous confidence intervals for the probabilities of a multinomial distribution given a set of observations, proposed by Sison and Glaz in their paper: Sison, C.P and J. Glaz. Simultaneous confidence intervals and sample size determination for multinomial proportions. Journal of the American Statistical Association, 90:366-369 (1995). The method is an R translation of the SAS code implemented by May and Johnson in their paper: May, W.L. and W.D. Johnson. Constructing two-sided simultaneous confidence intervals for multinomial proportions for small counts in a large number of cells. Journal of Statistical Software 5(6) (2000). Paper and code available at <DOI:10.18637/jss.v005.i06>.

Cancer cells accumulate DNA mutations as result of DNA damage and DNA repair processes. This computational framework is aimed at deciphering DNA mutational signatures operating in cancer. The framework includes modules that support raw data import and processing, mutational signature extraction, and results interpretation and visualization. The framework accepts widely used file formats storing information about DNA variants, such as Variant Call Format files. The framework performs Non-Negative Matrix Factorization to extract mutational signatures explaining the observed set of DNA mutations. Bootstrapping is performed as part of the analysis. The framework supports parallelization and is optimized for use on multi-core systems. The software was described by Fantini D et al (2020) <doi:10.1038/s41598-020-75062-0> and is based on a custom R-based implementation of the original MATLAB WTSI framework by Alexandrov LB et al (2013) <doi:10.1016/j.celrep.2012.12.008>.

Documentation at https://melpa.org/#/multistate

Documentation at https://melpa.org/#/multifiles

Documentation at https://melpa.org/#/multi-term

Documentation at https://melpa.org/#/multi-line

Documentation at https://melpa.org/#/mu4e-alert

Documentation at https://melpa.org/#/mu4e-views

This package provides a streaming multipart parser for Python.

This package provides a streaming multipart parser for Python.

This package provides a query interface for mu4e using Consult.

multidef provides a simple way of defining several macros having similar definitions.

Bytes go in, but they don't come out (when muted).

This package allows one to view and edit parts of multiple files in one Emacs buffer.