This package provides a set of spatial accessibility measures from a set of locations (demand) to another set of locations (supply). It aims, among others, to support research on spatial accessibility to health care facilities. Includes the locations and some characteristics of major public hospitals in Greece.

Complementary indexes calculation to the Outlying Mean Index analysis to explore niche shift of a community and biological constraint within an Euclidean space, with graphical displays. For details see Karasiewicz et al. (2017) <doi:10.7717/peerj.3364>.

Single-cell Interpretable Tensor Decomposition (scITD) employs the Tucker tensor decomposition to extract multicell-type gene expression patterns that vary across donors/individuals. This tool is geared for use with single-cell RNA-sequencing datasets consisting of many source donors. The method has a wide range of potential applications, including the study of inter-individual variation at the population-level, patient sub-grouping/stratification, and the analysis of sample-level batch effects. Each "multicellular process" that is extracted consists of (A) a multi cell type gene loadings matrix and (B) a corresponding donor scores vector indicating the level at which the corresponding loadings matrix is expressed in each donor. Additional methods are implemented to aid in selecting an appropriate number of factors and to evaluate stability of the decomposition. Additional tools are provided for downstream analysis, including integration of gene set enrichment analysis and ligand-receptor analysis. Tucker, L.R. (1966) <doi:10.1007/BF02289464>. Unkel, S., Hannachi, A., Trendafilov, N. T., & Jolliffe, I. T. (2011) <doi:10.1007/s13253-011-0055-9>. Zhou, G., & Cichocki, A. (2012) <doi:10.2478/v10175-012-0051-4>.

This package provides functionality to fit a zero-inflated estimator for small area estimation. This estimator is a combines a linear mixed effects regression model and a logistic mixed effects regression model via a two-stage modeling approach. The estimator's mean squared error is estimated via a parametric bootstrap method. Chandra and others (2012, <doi:10.1080/03610918.2011.598991>) introduce and describe this estimator and mean squared error estimator. White and others (2024+, <doi:10.48550/arXiv.2402.03263>) describe the applicability of this estimator to estimation of forest attributes and further assess the estimator's properties.

During the preparation of data set(s) one usually performs some sanity checks. The idea is that irrespective of where the checks are performed, they are centralized by this package in order to list all at once with examples if a check failed.

It is a single cell active pathway analysis tool based on the graph neural network (F. Scarselli (2009) <doi:10.1109/TNN.2008.2005605>; Thomas N. Kipf (2017) <arXiv:1609.02907v4>) to construct the gene-cell association network, infer pathway activity scores from different single cell modalities data, integrate multiple modality data on the same cells into one pathway activity score matrix, identify cell phenotype activated gene modules and parse association networks of gene modules under multiple cell phenotype. In addition, abundant visualization programs are provided to display the results.

Data related to the Salem Witch Trials Datasets and tutorials documenting the witch accusations and trials centered around Salem, Massachusetts in 1692. Originally assembled by Richard B. Latner of Tulane University for his website <https://www2.tulane.edu/~salem/index.html>. The data sets include information on 152 accused witches, members of the Salem Village Committee, signatories of petitions related to the events, and tax data for Salem Village.

Efficient variational inference methods for fully Bayesian Gaussian Process Regression (GPR) models with hierarchical shrinkage priors, including the triple gamma prior for effective variable selection and covariance shrinkage in high-dimensional settings. The package leverages normalizing flows to approximate complex posterior distributions. For details on implementation, see Knaus (2025) <doi:10.48550/arXiv.2501.13173>.

Easily analyze and visualize the performance of symptom checkers. This package can be used to gain comprehensive insights into the performance of single symptom checkers or the performance of multiple symptom checkers. It can be used to easily compare these symptom checkers across several metrics to gain an understanding of their strengths and weaknesses. The metrics are developed in Kopka et al. (2023) <doi:10.1177/20552076231194929>.

Fast k-nearest neighbors (K-NN) and principal component analysis (PCA) imputation algorithms for missing values in high-dimensional numeric matrices, i.e., epigenetic data. For extremely high-dimensional data with ordered features, a sliding window approach for K-NN or PCA imputation is provided. Additional features include group-wise imputation (e.g., by chromosome), hyperparameter tuning with repeated cross-validation, multi-core parallelization, and optional subset imputation. The K-NN algorithm is described in: Hastie, T., Tibshirani, R., Sherlock, G., Eisen, M., Brown, P. and Botstein, D. (1999) "Imputing Missing Data for Gene Expression Arrays". The PCA imputation is an optimized version of the imputePCA() function from the missMDA package described in: Josse, J. and Husson, F. (2016) <doi:10.18637/jss.v070.i01> "missMDA: A Package for Handling Missing Values in Multivariate Data Analysis".

This package implements the synthetic control group method for comparative case studies as described in Abadie and Gardeazabal (2003) and Abadie, Diamond, and Hainmueller (2010, 2011, 2014). The synthetic control method allows for effect estimation in settings where a single unit (a state, country, firm, etc.) is exposed to an event or intervention. It provides a data-driven procedure to construct synthetic control units based on a weighted combination of comparison units that approximates the characteristics of the unit that is exposed to the intervention. A combination of comparison units often provides a better comparison for the unit exposed to the intervention than any comparison unit alone.

This package provides a framework for extracting semantic motifs around entities in textual data. It implements an entity-centered semantic grammar that distinguishes six classes of motifs: actions of an entity, treatments of an entity, agents acting upon an entity, patients acted upon by an entity, characterizations of an entity, and possessions of an entity. Motifs are identified by applying a set of extraction rules to a parsed text object that includes part-of-speech tags and dependency annotations - such as those generated by spacyr'. For further reference, see: Stuhler (2022) <doi: 10.1177/00491241221099551>.

Hail is an open-source, general-purpose, python based data analysis tool with additional data types and methods for working with genomic data, see <https://hail.is/>. Hail is built to scale and has first-class support for multi-dimensional structured data, like the genomic data in a genome-wide association study (GWAS). Hail is exposed as a python library, using primitives for distributed queries and linear algebra implemented in scala', spark', and increasingly C++'. The sparkhail is an R extension using sparklyr package. The idea is to help R users to use hail functionalities with the well-know tidyverse syntax, see <https://www.tidyverse.org/>.

This package provides historical datasets related to John Snow's 1854 cholera outbreak study in London. Includes data on cholera cases, water pump locations, and the street layout, enabling analysis and visualisation of the outbreak.

We provide functions for estimation and inference of nonlinear and non-stationary time series regression using the sieve methods and bootstrapping procedure.

Simple class to hold contents of a SMET file as specified in Bavay (2021) <https://code.wsl.ch/snow-models/meteoio/-/blob/master/doc/SMET_specifications.pdf>. There numerical meteorological measurements are all based on MKS (SI) units and timestamp is standardized to UTC time.

This package provides a collection of statistical and geometrical tools including the aligned rank transform (ART; Higgins et al. 1990 <doi:10.4148/2475-7772.1443>; Peterson 2002 <doi:10.22237/jmasm/1020255240>; Wobbrock et al. 2011 <doi:10.1145/1978942.1978963>), 2-D histograms and histograms with overlapping bins, a function for making all possible formulae within a set of constraints, amongst others.

Implementation of the Conditional Least Square (CLS) estimates and its covariance matrix for the first-order spatial integer-valued autoregressive model (SINAR(1,1)) proposed by Ghodsi (2012) <doi:10.1080/03610926.2011.560739>.

This package provides a sparklyr extension package providing an integration with Google BigQuery'. It supports direct import/export where records are directly streamed from/to BigQuery'. In addition, data may be imported/exported via intermediate data extracts on Google Cloud Storage'.

Datasets and functions for the book "Statistiques pour lâ économie et la gestion", "Théorie et applications en entreprise", F. Bertrand, Ch. Derquenne, G. Dufrénot, F. Jawadi and M. Maumy, C. Borsenberger editor, (2021, ISBN:9782807319448, De Boeck Supérieur, Louvain-la-Neuve). The first chapter of the book is dedicated to an introduction to statistics and their world. The second chapter deals with univariate exploratory statistics and graphics. The third chapter deals with bivariate and multivariate exploratory statistics and graphics. The fourth chapter is dedicated to data exploration with Principal Component Analysis. The fifth chapter is dedicated to data exploration with Correspondance Analysis. The sixth chapter is dedicated to data exploration with Multiple Correspondance Analysis. The seventh chapter is dedicated to data exploration with automatic clustering. The eighth chapter is dedicated to an introduction to probability theory and classical probability distributions. The ninth chapter is dedicated to an estimation theory, one-sample and two-sample tests. The tenth chapter is dedicated to an Gaussian linear model. The eleventh chapter is dedicated to an introduction to time series. The twelfth chapter is dedicated to an introduction to probit and logit models. Various example datasets are shipped with the package as well as some new functions.

This implements the Brunton et al (2016; PNAS <doi:10.1073/pnas.1517384113>) sparse identification algorithm for finding ordinary differential equations for a measured system from raw data (SINDy). The package includes a set of additional tools for working with raw data, with an emphasis on cognitive science applications (Dale and Bhat, 2018 <doi:10.1016/j.cogsys.2018.06.020>). See <https://github.com/racdale/sindyr> for examples and updates.

This package provides a seamless design that combines phase I dose escalation based on toxicity with phase II dose expansion and dose comparison based on efficacy.

These are tools that allow users to do time series diagnostics, primarily tests of unit root, by way of simulation. While there is nothing necessarily wrong with the received wisdom of critical values generated decades ago, simulation provides its own perks. Not only is simulation broadly informative as to what these various test statistics do and what are their plausible values, simulation provides more flexibility for assessing unit root by way of different thresholds or different hypothesized distributions.

This package provides a collection of functions for estimating spatial regimes, aggregations of neighboring spatial units that are homogeneous in functional terms. The term spatial regime, therefore, should not be understood as a synonym for cluster. More precisely, the term cluster does not presuppose any functional relationship between the variables considered, while the term regime is linked to a regressive relationship underlying the spatial process.