This package provides essential Cleaning Validation functions for complying with pharmaceutical cleaning process regulatory standards. The package includes non-parametric methods to analyze drug active-ingredient residue (DAR), cleaning agent residue (CAR), and microbial colonies (Mic) for non-Poisson distributions. Additionally, Poisson methods are provided for Mic analysis when Mic data follow a Poisson distribution.
Scikit-rebate is a scikit-learn-compatible Python implementation of ReBATE, a suite of Relief-based feature selection algorithms for Machine Learning. These algorithms excel at identifying features that are predictive of the outcome in supervised learning problems, and are especially good at identifying feature interactions that are normally overlooked by standard feature selection algorithms.
Creation of tables of summary statistics or counts for clinical data (for TLFs'). These tables can be exported as in-text table (with the flextable package) for a Clinical Study Report (Word format) or a topline presentation (PowerPoint format), or as interactive table (with the DT package) to an html document for clinical data review.
Improve optical character recognition by binarizing images. The package focuses primarily on local adaptive thresholding algorithms. In English, this means that it has the ability to turn a color or gray scale image into a black and white image. This is particularly useful as a preprocessing step for optical character recognition or handwritten text recognition.
This package provides a wrapper of different methods from Linear Algebra for the equations introduced in The Atlas of Economic Complexity and related literature. This package provides standard matrix and graph output that can be used seamlessly with other packages. See <doi:10.21105/joss.01866> for a summary of these methods and its evolution in literature.
This package provides functions to predict one multi-way array (i.e., a tensor) from another multi-way array, using a low-rank CANDECOMP/PARAFAC (CP) factorization and a ridge (L_2) penalty [Lock, EF (2018) <doi:10.1080/10618600.2017.1401544>]. Also includes functions to sample from the Bayesian posterior of a tensor-on-tensor model.
returntogrid offers a few commands to get something like an simple, semi-automatic grid typesetting. It does more or less what the existing gridset package does. The main differences to gridset are that returntogrid works also with LuaLaTeX and that it has also a command to do some horizontal movements to get to Tab positions.
Allows the computation of clustering coefficients for directed and weighted networks by using different approaches. It allows to compute clustering coefficients that are not present in igraph package. A description of clustering coefficients can be found in "Directed clustering in weighted networks: a new perspective", Clemente, G.P., Grassi, R. (2017), <doi:10.1016/j.chaos.2017.12.007>.
The correction is achieved under the assumption that non-migrating cells of the essay approximately form a quadratic flow profile due to frictional effects, compare law of Hagen-Poiseuille for flow in a tube. The script fits a conical plane to give xyz-coordinates of the cells. It outputs the number of migrated cells and the new corrected coordinates.
Textual statistics functions formerly in the quanteda package. Textual statistics for characterizing and comparing textual data. Includes functions for measuring term and document frequency, the co-occurrence of words, similarity and distance between features and documents, feature entropy, keyword occurrence, readability, and lexical diversity. These functions extend the quanteda package and are specially designed for sparse textual data.
Customized training is a simple technique for transductive learning, when the test covariates are known at the time of training. The method identifies a subset of the training set to serve as the training set for each of a few identified subsets in the training set. This package implements customized training for the glmnet() and cv.glmnet() functions.
U-Boot is a bootloader used mostly for ARM boards. It also initializes the boards (RAM etc).
It allows network booting and uses the device-tree from the firmware, allowing the usage of overlays. It can act as an EFI firmware for the grub-efi-netboot-removable-bootloader. This is a 32-bit build of U-Boot.
U-Boot is a bootloader used mostly for ARM boards. It also initializes the boards (RAM etc).
It allows network booting and uses the device-tree from the firmware, allowing the usage of overlays. It can act as an EFI firmware for the grub-efi-netboot-removable-bootloader. This is a 32-bit build of U-Boot.
visual-replace provides an alternate interface for search and replacement commands that supports previews. The interface also allows one to edit both the query-text and its replacement in the same minibuffer prompt. The interface covers the following commands:
replace-stringreplace-regexpquery-replacequery-replace-regexp
An inverse probability of censoring weighted (IPCW) targeted maximum likelihood estimator (TMLE) for evaluating a marginal point treatment effect from data where some variables were collected on only a subset of participants using a two-stage design (or marginal mean outcome for a single arm study). A TMLE for conditional parameters defined by a marginal structural model (MSM) is also available.
The statistical analysis of circular data using distributions based on symmetric Nonnegative Trigonometric Sums (NNTS). It includes functions to perform empirical analysis and estimate the parameters of density functions. Fernandez-Duran, J.J. and Gregorio-Dominguez, M.M. (2025), "Multimodal Symmetric Circular Distributions Based on Nonnegative Trigonometric Sums and a Likelihood Ratio Test for Reflective Symmetry", <doi:10.48550/arXiv.2412.19501>.
This package provides a suite of descriptive and inferential methods designed to evaluate one or more biomarkers for their ability to guide patient treatment recommendations. Package includes functions to assess the calibration of risk models; and plot, evaluate, and compare markers. Please see the reference Janes H, Brown MD, Huang Y, et al. (2014) <doi:10.1515/ijb-2012-0052> for further details.
Presentation two independence tests for two-way, three-way and four-way contingency tables. These tests are: the modular test and the logarithmic minimum test. For details on this method see: Sulewski (2017) <doi:10.18778/0208-6018.330.04>, Sulewski (2018) <doi:10.1080/02664763.2018.1424122>, Sulewski (2019) <doi:10.2478/bile-2019-0003>, Sulewski (2021) <doi:10.1080/00949655.2021.1908286>.
This package provides a dynamic allocator that may be used with or without the stdlib. This allows a package with nostd to allocate memory dynamically and be used either with a custom allocator, items on the stack, or by a package that wishes to simply use Box<>. It also provides options to use calloc or a mutable global variable for pre-zeroed memory.
Determine and test the fixed-point property in binary mixture data. This package was originally developed in the context of detecting mixture of cognitive processing strategies, based on observed response time distributions. The method is explain in more detail by Van Maanen, De Jong, Van Rijn (2014) <doi:10.1371/journal.pone.0106113> and Van Maanen, Couto, Lebreton, (2016) <doi:10.1371/journal.pone.0167377>.
We perform general mediation analysis in the Bayesian setting using the methods described in Yu and Li (2022, ISBN:9780367365479). With the package, the mediation analysis can be performed on different types of outcomes (e.g., continuous, binary, categorical, or time-to-event), with default or user-defined priors and predictive models. The Bayesian estimates and credible sets of mediation effects are reported as analytic results.
Allows local bone density estimates to be derived from CT data and mapped to 3D bone models in a reproducible manner. Processing can be performed at the individual bone or group level. Also includes tools for visualizing the bone density estimates. Example methods are described in Telfer et al., (2021) <doi:10.1002/jor.24792>, Telfer et al., (2021) <doi:10.1016/j.jse.2021.05.011>.
Facilitates the creation of xpose data objects from Nonlinear Mixed Effects (NLME) model outputs produced by Certara.RsNLME or Phoenix NLME. This integration enables users to utilize all ggplot2'-based plotting functions available in xpose for thorough model diagnostics and data visualization. Additionally, the package introduces specialized plotting functions tailored for covariate model evaluation, extending the analytical capabilities beyond those offered by xpose alone.
This package provides a set of functions to investigate raw data from (metabol)omics experiments intended to be used on a raw data matrix, i.e. following peak picking and signal deconvolution. Functions can be used to normalize data, detect biomarkers and perform sample classification. A detailed description of best practice usage may be found in the publication <doi:10.1007/978-1-4939-7819-9_20>.