Estimate and forecast Bayesian simultaneous equation models for macroeconomic time series. Provides tools to specify systems of behavioral equations and accounting identities, transform and manage time series, simulate from the posterior using a Metropolis-within-Gibbs sampler, and generate unconditional and conditional forecasts with user-defined priors and restrictions. Methods are described in Rathke A. and Sarferaz S. (forthcoming) "Bayesian Estimation of Simultaneous Equations Model".

This package contains a set of functions to create data libraries, generate data dictionaries, and simulate a data step. The libname() function will load a directory of data into a library in one line of code. The dictionary() function will generate data dictionaries for individual data frames or an entire library. And the datestep() function will perform row-by-row data processing.

Due to lack of proper inference procedure and software, the ordinary linear regression model is seldom used in practice for the analysis of right censored data. This paper presents an S-Plus/R program that implements a recently developed inference procedure (Jin, Lin and Ying, 2006) <doi:10.1093/biomet/93.1.147> for the accelerated failure time model based on the least-squares principle.

Classification method obtained through linear programming. It is advantageous with respect to the classical developments when the distribution of the variables involved is unknown or when the number of variables is much greater than the number of individuals. Mathematical details behind the method are published in Nueda, et al. (2022) "LPDA: A new classification method based on linear programming". <doi:10.1371/journal.pone.0270403>.

This package performs multiple imputation of missing data using an ensemble super learner built with the tidymodels framework. For each incomplete column, a stacked ensemble of candidate learners is trained on a bootstrap sample of the observed data and used to generate imputations via predictive mean matching (continuous), probability draws (binary), or cumulative probability draws (categorical). Supports parallelism across imputed datasets via the future framework.

This package provides new functions info(), warn() and error(), similar to message(), warning() and stop() respectively. However, the new functions can have a level associated with them, so that when executed the global level option determines whether they are shown or not. This allows debug modes, outputting more information. The can also output all messages to a log file.

Ordered homogeneity pursuit lasso (OHPL) algorithm for group variable selection proposed in Lin et al. (2017) <DOI:10.1016/j.chemolab.2017.07.004>. The OHPL method exploits the homogeneity structure in high-dimensional data and enjoys the grouping effect to select groups of important variables automatically. This feature makes it particularly useful for high-dimensional datasets with strongly correlated variables, such as spectroscopic data.

This package provides a system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.

This package implements recently developed projection pursuit algorithms for finding optimal linear cluster separators. The clustering algorithms use optimal hyperplane separators based on minimum density, Pavlidis et. al (2016) <http://jmlr.org/papers/volume17/15-307/15-307.pdf>; minimum normalised cut, Hofmeyr (2017) <doi:10.1109/TPAMI.2016.2609929>; and maximum variance ratio clusterability, Hofmeyr and Pavlidis (2015) <doi:10.1109/SSCI.2015.116>.

This package provides a collection of functions to simulate, estimate and forecast a wide range of regression based dynamic models for positive time series. This package implements the results presented in Prass, T.S.; Pumi, G.; Taufemback, C.G. and Carlos, J.H. (2025). "Positive time series regression models: theoretical and computational aspects". Computational Statistics 40, 1185â 1215. <doi:10.1007/s00180-024-01531-z>.

This package provides an R interface to SCIP (Solving Constraint Integer Programs), a framework for mixed-integer programming (MIP), mixed-integer nonlinear programming (MINLP), and constraint integer programming (2025, <doi:10.48550/arXiv.2511.18580>). Supports linear, quadratic, SOS, indicator, and knapsack constraints with continuous, binary, and integer variables. Includes a one-shot solver interface and a model-building API for incremental problem construction.

Spatial Stochastic Frontier Analysis (SSFA) is an original method for controlling the spatial heterogeneity in Stochastic Frontier Analysis (SFA) models, for cross-sectional data, by splitting the inefficiency term into three terms: the first one related to spatial peculiarities of the territory in which each single unit operates, the second one related to the specific production features and the third one representing the error term.

We provide a flexible Zero-inflated Poisson-Gamma Model (ZIPG) by connecting both the mean abundance and the variability to different covariates, and build valid statistical inference procedures for both parameter estimation and hypothesis testing. These functions can be used to analyze microbiome count data with zero-inflation and overdispersion. The model is discussed in Jiang et al (2023) <doi:10.1080/01621459.2022.2151447>.

Parameter estimation for zero-inflated discrete Weibull (ZIDW) regression models, the univariate setting, distribution functions, functions to generate randomized quantile residuals a pseudo R2, and plotting of rootograms. For more details, see Kalktawi (2017) <https://bura.brunel.ac.uk/handle/2438/14476>, Taconeli and Rodrigues de Lara (2022) <doi:10.1080/00949655.2021.2005597>, and Yeh and Young (2025) <doi:10.1080/03610918.2025.2464076>.

Logging functions in RcppSpdlog provide access to the logging functionality from the spdlog C++ library. This package offers shorter convenience wrappers for the R functions which match the C++ functions, namely via, say, spdl::debug() at the debug level. The actual formatting is done by the fmt::format() function from the fmtlib library (that is also std::format() in C++20 or later).

The curl() and curl_download() functions provide highly configurable drop-in replacements for base url() and download.file() with better performance, support for encryption, gzip compression, authentication, and other libcurl goodies. The core of the package implements a framework for performing fully customized requests where data can be processed either in memory, on disk, or streaming via the callback or connection interfaces.

qsea (quantitative sequencing enrichment analysis) was developed as the successor of the MEDIPS package for analyzing data derived from methylated DNA immunoprecipitation (MeDIP) experiments followed by sequencing (MeDIP-seq). However, qsea provides several functionalities for the analysis of other kinds of quantitative sequencing data (e.g. ChIP-seq, MBD-seq, CMS-seq and others) including calculation of differential enrichment between groups of samples.

This package provides memory-efficient biweight midcorrelation and exact bicor-based k-nearest-neighbor graph construction for dense and sparse numeric matrices. Dense, sparse, and mixed-input paths avoid materializing full dense similarity matrices for tidy and k-nearest-neighbor workflows where possible. The implementation supports pairwise finite-overlap handling and robust correlation-based graph construction for biological expression matrices and other high-dimensional numeric data.

Single linkage clustering and connected component analyses are often performed on biological images. Bioi provides a set of functions for performing these tasks. This functionality is implemented in several key functions that can extend to from 1 to many dimensions. The single linkage clustering method implemented here can be used on n-dimensional data sets, while connected component analyses are limited to 3 or fewer dimensions.

This package provides a tool to use a principal component analysis on radially averaged two dimensional Fourier spectra to characterize image texture. The method within the context of ecology was first described by Couteron et al. (2005) <doi:10.1111/j.1365-2664.2005.01097.x> and expanded upon by Solorzano et al. (2018) <doi:10.1117/1.JRS.12.036006> using a moving window approach.

We propose a fully efficient sieve maximum likelihood method to estimate genotype-specific distribution of time-to-event outcomes under a nonparametric model. We can handle missing genotypes in pedigrees. We estimate the time-dependent hazard ratio between two genetic mutation groups using B-splines, while applying nonparametric maximum likelihood estimation to the reference baseline hazard function. The estimators are calculated via an expectation-maximization algorithm.

Fit a regression model for when the response variable is presented as a ratio or proportion. This adjustment can occur globally, with the same estimate for the entire study space, or locally, where a beta regression model is fitted for each region, considering only influential locations for that area. Da Silva, A. R. and Lima, A. O. (2017) <doi:10.1016/j.spasta.2017.07.011>.

Generates random numbers corresponding to the events on a Poisson point process with changing event rates. This includes the possibility to incorporate additional information such as the number of events occurring or the location of an already known event. It can also generate the probability density functions of specific events in the cases where additional information is available. Based on Hohmann (2019) <arXiv:1901.10754>.

Computes bootstrapped Monte Carlo estimate of p value of Kolmogorov-Smirnov (KS) test and likelihood ratio test for zero-inflated count data, based on the work of Aldirawi et al. (2019) <doi:10.1109/BHI.2019.8834661>. With the package, user can also find tools to simulate random deviates from zero inflated or hurdle models and obtain maximum likelihood estimate of unknown parameters in these models.