This package provides a framework for the creation and use of Neural ordinary differential equations with the tensorflow and keras packages. The idea of Neural ordinary differential equations comes from Chen et al. (2018) <doi:10.48550/arXiv.1806.07366>, and presents a novel way of learning and solving differential systems.

Unit testing is a solid component of automated CI/CD pipelines. tinytest - a lightweight, zero-dependency alternative to testthat was developed. To be able to integrate tinytests results into common CI/CD systems the tinytests'-object is converted to JUnit XML format. tinytest2JUnit enables this conversion while staying lightweight, having only tinytest as its dependency.

Univariate time series operations that follow an opinionated design. The main principle of transx is to keep the number of observations the same. Operations that reduce this number have to fill the observations gap.

The classical two-sample t-test works well for the normally distributed data or data with large sample size. The tcfu() and tt() tests implemented in this package provide better type-I-error control with more accurate power when testing the equality of two-sample means for skewed populations having unequal variances. These tests are especially useful when the sample sizes are moderate. The tcfu() uses the Cornish-Fisher expansion to achieve a better approximation to the true percentiles. The tt() provides transformations of the Welch's t-statistic so that the sampling distribution become more symmetric. For more technical details, please refer to Zhang (2019) <http://hdl.handle.net/2097/40235>.

This package provides a common way of validating a biological assay for is through a procedure, where m levels of an analyte are measured with n replicates at each level, and if all m estimates of the coefficient of variation (CV) are less than some prespecified level, then the assay is declared validated for precision within the range of the m analyte levels. Two limitations of this procedure are: there is no clear statistical statement of precision upon passing, and it is unclear how to modify the procedure for assays with constant standard deviation. We provide tools to convert such a procedure into a set of m hypothesis tests. This reframing motivates the m:n:q procedure, which upon completion delivers a 100q% upper confidence limit on the CV. Additionally, for a post-validation assay output of y, the method gives an ``effective standard deviation interval of log(y) plus or minus r, which is a 68% confidence interval on log(mu), where mu is the expected value of the assay output for that sample. Further, the m:n:q procedure can be straightforwardly applied to constant standard deviation assays. We illustrate these tools by applying them to a growth inhibition assay. This is an implementation of the methods described in Fay, Sachs, and Miura (2018) <doi:10.1002/sim.7528>.

This package implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.

Temporal SNA tools for continuous- and discrete-time longitudinal networks having vertex, edge, and attribute dynamics stored in the networkDynamic format. This work was supported by grant R01HD68395 from the National Institute of Health.

Create "good enough" tables with a single formula. tablespan tables can be exported to Excel', HTML', LaTeX', and RTF by leveraging the packages openxlsx and gt'. See <https://jhorzek.github.io/tablespan/> for an introduction.

Tautulli (<http://tautulli.com>) is a monitoring application for Plex Media Servers (<https://www.plex.tv>) which collects a lot of data about media items and server usage such as play counts. This package interacts with the Tautulli API of any specified server to get said data into R. The Tautulli API documentation is available at <https://github.com/Tautulli/Tautulli/blob/master/API.md>.

This package provides a tufte'-alike style for rmarkdown'. A modern take on the Tufte design for pdf and html vignettes, building on the tufte package with additional contributions from the knitr and ggtufte package, and also acknowledging the key influence of envisioned css'.

Implement the Tariff algorithm for coding cause-of-death from verbal autopsies. The Tariff method was originally proposed in James et al (2011) <DOI:10.1186/1478-7954-9-31> and later refined as Tariff 2.0 in Serina, et al. (2015) <DOI:10.1186/s12916-015-0527-9>. Note that this package was not developed by authors affiliated with the Institute for Health Metrics and Evaluation and thus unintentional discrepancies may exist between the this implementation and the implementation available from IHME.

This package provides a consistent API for classification and regression models based on the TabPFN model of Hollmann et al. (2025), "Accurate predictions on small data with a tabular foundation model," Nature, 637(8045) <doi:10.1038/s41586-024-08328-6>. The calculations are served via Python to train and predict the model.

When using the R package exams to write mathematics questions in Sweave files, the output of a lot of R functions need to be adjusted for display in mathematical formulas. Specifically, the functions were accumulated when writing questions for the topics of the mathematics courses College Algebra, Precalculus, Calculus, Differential Equations, Introduction to Probability, and Linear Algebra. The output of the developed functions can be used in Sweave files.

This package provides a set of functions that allow users for styling their R code according to the tidyverse style guide. The package uses a native Rust implementation to ensure the highest performance. Learn more about tergo at <https://rtergo.pagacz.io>.

Imports non-tabular from Excel files into R. Exposes cell content, position and formatting in a tidy structure for further manipulation. Tokenizes Excel formulas. Supports .xlsx and .xlsm via the embedded RapidXML C++ library <https://rapidxml.sourceforge.net>. Does not support .xlsb or .xls'.

Simplify reporting many tables by creating tibbles of tables. With tabtibble', a tibble of tables is created with captions and automatic printing using knit_print()'.

This package implements triple-difference (DDD) estimators for both average treatment effects and event-study parameters. Methods include regression adjustment, inverse-probability weighting, and doubly-robust estimators, all of which rely on a conditional DDD parallel-trends assumption and allow covariate adjustment across multiple pre- and post-treatment periods. The methodology is detailed in Ortiz-Villavicencio and Sant'Anna (2025) <doi:10.48550/arXiv.2505.09942>.

This package provides tools for constructing conditional two-dimensional reference regions in continuous data, particularly suited for clinical, biological, or epidemiological studies requiring robust multivariate assessment. The implemented methodology combines directional quantiles with medianâ based partial correlation models to produce reliable and interpretable reference regions even in the presence of outliers. Key features include robust conditional modeling for two responses conditioned on covariates, directional quantile regions, crossâ validation of coverage, visualization tools, and flexible formulaâ based inputs.

Builds tables with customizable rows. Users can specify the type of data to use for each row, as well as how to handle missing data and the types of comparison tests to run on the table columns.

The tmap package provides two plotting modes for static and interactive thematic maps. This package extends tmap with two additional modes based on Mapbox GL JS and MapLibre GL JS'. These modes feature interactive vector tiles, globe views, and other modern web-mapping capabilities, while maintaining a consistent tmap interface across all plotting modes.

In some phase I trials, the design goal is to find the dose associated with a certain target toxicity rate or the dose with a certain weighted sum of rates of various toxicity grades. TITEgBOIN provides the set up and calculations needed to run a dose-finding trial using bayesian optimal interval (BOIN) (Yuan et al. (2016) <doi:10.1158/1078-0432.CCR-16-0592>), generalized bayesian optimal interval (gBOIN) (Mu et al. (2019) <doi:10.1111/rssc.12263>), time-to-event bayesian optimal interval (TITEBOIN) (Lin et al. (2020) <doi:10.1093/biostatistics/kxz007>) and time-to-event generalized bayesian optimal interval (TITEgBOIN) (Takeda et al. (2022) <doi:10.1002/pst.2182>) designs. TITEgBOIN can conduct tasks: run simulations and get operating characteristics; determine the dose for the next cohort; select maximum tolerated dose (MTD). These functions allow customization of design characteristics to vary sample size, cohort sizes, target dose limiting toxicity (DLT) rates or target normalized equivalent toxicity score (ETS) rates to account for discrete toxicity score, and incorporate safety and/or stopping rules.

This package provides methods for generating .dat files for use with the AMPL software using spatial data, particularly rasters. It includes support for various spatial data formats and different problem types. By automating the process of generating AMPL datasets, this package can help streamline optimization workflows and make it easier to solve complex optimization problems. The methods implemented in this package are described in detail in a publication by Fourer et al. (<doi:10.1287/mnsc.36.5.519>).

This package provides a screening process utilizing training and testing samples to filter out uninformative DNA methylation sites. Surrogate variables (SVs) of DNA methylation are included in the filtering process to explain unknown factor effects. This package also provides two screening functions for screening high-dimensional predictors when the events are rare. The firth method is called Rare-Screening which employs a repeated random sampling with replacement and using linear modeling with Bayes adjustment. The Second method is called Firth-ttScreening which uses ttScreening method with additional Firth correction term in the maximum likelihood for the logistic regression model. These methods handle the high-dimensionality and low event rates.

Calculate Characteristics of Quasi-Periodic Time Series, e.g. Estuarine Water Levels.