This package implements Bayesian hierarchical models for estimating antibody kinetic parameters from longitudinal serological data. Fits two-phase within-host models capturing antibody rise, peak, and decay following pathogen infection, using JAGS for posterior inference. Designed as the upstream companion to the serocalculator package for end-to-end seroepidemiological analysis. Methods are described in Teunis and colleagues (2016) <doi:10.1016/j.epidem.2016.04.001> and Teunis and van Eijkeren (2020) <doi:10.1002/sim.8578>.

This package provides dplyr and tidyr verbs, survey-aware recoding helpers, and row-wise statistics for survey design objects created with the surveycore package. filter() uses domain estimation to preserve variance estimation validity; other verbs preserve design variables and metadata automatically. Also supports survey_collection objects for applying the same operation across a list of surveys.

Determines Optimum Strata Boundaries (OSB) and Optimum Sample Sizes (OSS) for univariate stratified sampling designs under Neyman allocation. The stratification variable is described by a best-fitting parametric distribution, selected automatically by AIC from a set of continuous families (normal, log-normal, gamma, Weibull, exponential, Cauchy, uniform, Pareto, triangular and right-triangular), and the optimum boundaries are obtained by minimising the Neyman objective. Version 2.0 keeps the original globally optimal Dynamic Programming (DP) solver of Reddy and Khan (2020) as the default and adds two faster derivative-free alternatives for interactive and large-scale use: a multi-start COBYLA solver and a two-phase global solver that couples DIRECT-L with COBYLA refinement. It also provides cost-constrained allocation with unequal per-stratum costs, a design-efficiency comparison (compare_designs), two- and three-dimensional and interactive visualisations, solution-quality diagnostics (a Cauchy-Schwarz optimality gap and KKT first-order residuals for the derivative-free solvers) and a self-contained shiny application, while remaining backward compatible with the strata.data() and strata.distr() interface of version 1.x. The methodology follows Khan et al. (2008) <https://www150.statcan.gc.ca/n1/pub/12-001-x/2008002/article/10761-eng.pdf>, Reddy and Khan (2018) <doi:10.1111/anzs.12244> and Reddy and Khan (2020) <doi:10.1111/anzs.12301>.

Chat with large language models on your machine without internet with complete privacy via ollama', powered by R shiny interface. For more information on ollama', visit <https://ollama.com>.

Survival analysis with sparse longitudinal covariates under right censoring scheme. Different hazards models are involved. Please cite the manuscripts corresponding to this package: Sun, Z. et al. (2022) <doi:10.1007/s10985-022-09548-6>, Sun, Z. and Cao, H. (2023) <arXiv:2310.15877> and Sun, D. et al. (2023) <arXiv:2308.15549>.

This package provides a software package help user to create virtual species for species distribution modelling. It includes several methods to help user to create virtual species distribution map. Those maps can be used for Species Distribution Modelling (SDM) study. SDM use environmental data for sites of occurrence of a species to predict all the sites where the environmental conditions are suitable for the species to persist, and may be expected to occur.

Dictionary-like reference for computing scoring rules in a wide range of situations. Covers both parametric forecast distributions (such as mixtures of Gaussians) and distributions generated via simulation. Further details can be found in the package vignettes <doi:10.18637/jss.v090.i12>, <doi:10.18637/jss.v110.i08>.

This package provides a socket server allows to connect clients to R.

We provide functionality to implement penalized PCA with an option to smooth the objective function using Nesterov smoothing. Two functions are available to compute a user-specified number of eigenvectors. The function unsmoothed_penalized_EV() computes a penalized PCA without smoothing and has three parameters (the input matrix, the Lasso penalty, and the number of desired eigenvectors). The function smoothed_penalized_EV() computes a smoothed penalized PCA using the same parameters and additionally requires the specification of a smoothing parameter. Both functions return a matrix having the desired eigenvectors as columns.

This package provides functions that provide statistical methods for interval-censored (grouped) data. The package supports the estimation of linear and linear mixed regression models with interval-censored dependent variables. Parameter estimates are obtained by a stochastic expectation maximization algorithm. Furthermore, the package enables the direct (without covariates) estimation of statistical indicators from interval-censored data via an iterative kernel density algorithm. Survey and Organisation for Economic Co-operation and Development (OECD) weights can be included into the direct estimation (see, Walter, P. (2019) <doi:10.17169/refubium-1621>).

Substitution matrices are important parameters in protein alignment algorithms. These matrices represent the likelihood that an amino acid will be substituted for another during mutation. This tool allows users to apply predefined and custom matrices and then explore the resulting alignments with interactive visualizations. SubVis requires the availability of a web browser.

Computes a proportional trimmed mean that resolves the integer truncation problem of base R's mean(..., trim). When k = trim * n is non-integer, a fractional discount (1 - delta) is applied to boundary observations, where delta = k - floor(k). The resulting estimator is continuous in alpha for any fixed n, syntactically identical to mean(..., trim), and compatible with the Statgraphics implementation. See Gaviria Chaverra (2026) <doi:10.32614/CRAN.package.sgmean>.

Statistical analysis of spatio-temporal point processes on linear networks. This packages provides tools to visualise and analyse spatio-temporal point patterns on linear networks using first, second, and higher-order summary statistics.

Analyzes shooting data with respect to group shape, precision, and accuracy. This includes graphical methods, descriptive statistics, and inference tests using standard, but also non-parametric and robust statistical methods. Implements distributions for radial error in bivariate normal variables. Works with files exported by OnTarget PC/TDS', Silver Mountain e-target, ShotMarker e-target, SIUS e-target, or Taran', as well as with custom data files in text format. Supports inference from range statistics such as extreme spread. Includes a set of web-based graphical user interfaces.

This package provides a powerful, easy to use syntax for specifying and estimating complex Structural Equation Models. Models can be estimated using Partial Least Squares Path Modeling or Covariance-Based Structural Equation Modeling or covariance based Confirmatory Factor Analysis (Ray, Danks, and Valdez 2021 <doi:10.2139/ssrn.3900621>).

This package provides a framework for performing simulations such as those common in methodological statistics papers. The design principles of this package are described in greater depth in Bien, J. (2016) "The simulator: An Engine to Streamline Simulations," which is available at <arXiv:1607.00021>.

This package implements the revised Synthetic Matching Algorithm of Kreitmeir, Lane, and Raschky (2025) <doi:10.2139/ssrn.3751162>, building on the original approach of Acemoglu, Johnson, Kermani, Kwak, and Mitton (2016) <doi:10.1016/j.jfineco.2015.10.001>, to estimate the cumulative treatment effect of an event on treated firmsâ stock returns.

Universal and robust algorithm for solving the total alkalinity-pH equation presented in G. Munhoven (2013) <doi:10.5194/gmd-6-1367-2013> and G. Munhoven (2021) <doi:10.5194/gmd-2020-447>. The total alkalinity-pH equation relates total alkalinity and pH for a given set of acid-base concentrations in a given water sample, among which carbonic acid. This package is particularly useful in marine chemistry involving dissolved inorganic carbon. Original package in Fortran can be found at <doi:10.5281/zenodo.4328965>.

This package provides a graphical user interface (GUI) for fitting Bayesian regression models using the package brms which in turn relies on Stan (<https://mc-stan.org/>). The shinybrms GUI is a shiny app.

Full text, in data frames containing one row per verse, of the Standard Works of The Church of Jesus Christ of Latter-day Saints (LDS). These are the Old Testament, (KJV), the New Testament (KJV), the Book of Mormon, the Doctrine and Covenants, and the Pearl of Great Price.

Detection of item-wise Differential Item Functioning (DIF) in fitted mirt', multipleGroup or bfactor models using score-based structural change tests. Under the hood the sctest() function from the strucchange package is used.

Offers a rich and diverse collection of datasets focused on sports, athletics, physical performance, and related disciplines. The package includes professional and amateur sports data covering team sports such as soccer, basketball, baseball, American football, volleyball, rugby, cricket, hockey, and handball, as well as individual sports including tennis, badminton, table tennis, golf, swimming, cycling, athletics, gymnastics, wrestling, boxing, martial arts, weightlifting, triathlon, rowing, canoeing, climbing, surfing, skiing, snowboarding, and motorsports. Datasets cover player and team performance, match statistics, tournament results, championship standings, Olympic and international competitions, rankings, player demographics, coaching and training, biomechanics, sports medicine, injuries, exercise physiology, fitness assessment, sports nutrition, wearable sensor measurements, talent identification, and sports analytics. Additional datasets include historical competitions, referee decisions, fan engagement, economic indicators, and sports management data obtained from public repositories, official organizations, research publications, and educational resources. Designed for sports scientists, coaches, analysts, researchers, educators, students, and data scientists, this package facilitates exploratory data analysis, statistical modeling, machine learning, visualization, and sports analytics research.

Utility functions for scale-dependent and alternative hyperpriors. The distribution parameters may capture location, scale, shape, etc. and every parameter may depend on complex additive terms (fixed, random, smooth, spatial, etc.) similar to a generalized additive model. Hyperpriors for all effects can be elicitated within the package. Including complex tensor product interaction terms and variable selection priors. The basic model is explained in in Klein and Kneib (2016) <doi:10.1214/15-BA983>.

This package provides a workflow based on scTenifoldNet to perform in-silico knockout experiments using single-cell RNA sequencing (scRNA-seq) data from wild-type (WT) control samples as input. First, the package constructs a single-cell gene regulatory network (scGRN) and knocks out a target gene from the adjacency matrix of the WT scGRN by setting the geneâ s outdegree edges to zero. Then, it compares the knocked out scGRN with the WT scGRN to identify differentially regulated genes, called virtual-knockout perturbed genes, which are used to assess the impact of the gene knockout and reveal the geneâ s function in the analyzed cells.