Calculates performance criteria measures and associated Monte Carlo standard errors for simulation results. Includes functions to help run simulation studies, following a general simulation workflow that closely aligns with the approach described by Morris, White, and Crowther (2019) <DOI:10.1002/sim.8086>. Also includes functions for calculating bootstrap confidence intervals (including normal, basic, studentized, percentile, bias-corrected, and bias-corrected-and-accelerated) with tidy output, as well as for extrapolating confidence interval coverage rates and hypothesis test rejection rates following techniques suggested by Boos and Zhang (2000) <DOI:10.1080/01621459.2000.10474226>.

This package performs simulations of binary spatial raster data using the Ising model (Ising (1925) <doi:10.1007/BF02980577>; Onsager (1944) <doi:10.1103/PhysRev.65.117>). It allows to set a few parameters that represent internal and external pressures, and the number of simulations (Stepinski and Nowosad (2023) <doi:10.1098/rsos.231005>).

This package provides a set of user interface components to create outstanding shiny apps <https://shiny.posit.co/>, with the power of React JavaScript <https://react.dev/>. Seamlessly support dark and light themes, customize CSS with tailwind <https://tailwindcss.com/>.

An iterative feature selection method that internally utilizes various Machine Learning methods that have embedded feature reduction in order to shrink down the feature space into a small and yet robust set.

This package provides a suite of statistical methods for analysis of single-cell omics data including linear model-based methods for differential abundance analysis for individual level single-cell RNA-seq data. For more details see Zhang, et al. (Submitted to Bioinformatics)<https://github.com/Lujun995/DiSC_Replication_Code>.

This package provides a tool to interactively explore the embeddings created by dimension reduction methods such as Principal Components Analysis (PCA), Multidimensional Scaling (MDS), T-distributed Stochastic Neighbour Embedding (t-SNE), Uniform Manifold Approximation and Projection (UMAP) or any other.

Seamless and standardized interaction with data exported from the clinical data management system (CDMS) secuTrial'<https://www.secutrial.com>. The primary data export the package works with is a standard non-rectangular export.

This package provides an easy-to-use module for adding a chat to a Shiny app. Allows users to send messages and view messages from other users. Messages can be stored in a database or a .rds file.

Uses parametric and nonparametric methods to quantify the proportion of the estimated selection bias (SB) explained by each observed confounder when estimating propensity score weighted treatment effects. Parast, L and Griffin, BA (2020). "Quantifying the Bias due to Observed Individual Confounders in Causal Treatment Effect Estimates". Statistics in Medicine, 39(18): 2447- 2476 <doi: 10.1002/sim.8549>.

These are tools that allow users to do time series diagnostics, primarily tests of unit root, by way of simulation. While there is nothing necessarily wrong with the received wisdom of critical values generated decades ago, simulation provides its own perks. Not only is simulation broadly informative as to what these various test statistics do and what are their plausible values, simulation provides more flexibility for assessing unit root by way of different thresholds or different hypothesized distributions.

Stock-and-flow models are a computational method from the field of system dynamics. They represent how systems change over time and are mathematically equivalent to ordinary differential equations. sdbuildR (system dynamics builder) provides an intuitive interface for constructing stock-and-flow models without requiring extensive domain knowledge. Models can quickly be simulated and revised, supporting iterative development. sdbuildR simulates models in R and Julia', and supports computationally intensive ensemble simulations. Additionally, sdbuildR can import models created in Insight Maker (<https://insightmaker.com/>).

Predictive margins like in the Stata procedure margins'. This package is based on the survey::svypredmean() function. Supported regression analyses are based on survey::svyglm() and svyVGAM::svy_vglm() functions (for multinomial logistic regression models).

The function generates and plots random snowflakes. Each snowflake is defined by a given diameter, width of the crystal, color, and random seed. Snowflakes are plotted in such way that they always remain round, no matter what the aspect ratio of the plot is. Snowflakes can be created using transparent colors, which creates a more interesting, somewhat realistic, image. Images of the snowflakes can be separately saved as svg files and used in websites as static or animated images.

This package provides functions for fitting, forecasting, and early detection of outbreaks in sparse surveillance count time series. Supports negative binomial (NB), self-exciting NB, generalise autoregressive moving average (GARMA) NB , zero-inflated NB (ZINB), self-exciting ZINB, generalise autoregressive moving average ZINB, and hurdle formulations. Climatic and environmental covariates can be included in the regression component and/or the zero-modified components. Includes outbreak-detection algorithms for NB, ZINB, and hurdle models, with utilities for prediction and diagnostics.

SqueezeMeta is a versatile pipeline for the automated analysis of metagenomics/metatranscriptomics data (<https://github.com/jtamames/SqueezeMeta>). This package provides functions loading SqueezeMeta results into R, filtering them based on different criteria, and visualizing the results using basic plots. The SqueezeMeta project (and any subsets of it generated by the different filtering functions) is parsed into a single object, whose different components (e.g. tables with the taxonomic or functional composition across samples, contig/gene abundance profiles) can be easily analyzed using other R packages such as vegan or DESeq2'. The methods in this package are further described in Puente-Sánchez et al., (2020) <doi:10.1186/s12859-020-03703-2>.

This package provides methods to calculate sample size for single-arm survival studies using the arcsine transformation, incorporating uniform accrual and exponential survival assumptions. Includes functionality for detailed numerical integration and simulation. This method is based on Nagashima et al. (2021) <doi:10.1002/pst.2090>.

Simulate genotypes in SNP (single nucleotide polymorphisms) Matrix as random numbers from an uniform distribution, for diploid organisms (coded by 0, 1, 2), Sikorska et al., (2013) <doi:10.1186/1471-2105-14-166>, or half-sib/full-sib SNP matrix from real or simulated parents SNP data, assuming mendelian segregation. Simulate phenotypic traits for real or simulated SNP data, controlled by a specific number of quantitative trait loci and their effects, sampled from a Normal or an Uniform distributions, assuming a pure additive model. This is useful for testing association and genomic prediction models or for educational purposes.

This package provides a set of plotting methods for simmer trajectories and simulations.

Setwise Hierarchical Rate of Erroneous Discovery (SHRED) methods for setwise variable selection with false discovery rate (FDR) control. Setwise variable selection means that sets of variables may be selected when the true variable cannot be identified. This allows us to maintain FDR control but increase power. Details of the SHRED methods are in Organ, Kenney & Gu (2026) <doi:10.48550/arXiv.2603.02160>.

This package provides a very nice interface to Princeton's WordNet without rJava dependency. WordNet data is not included. Princeton University makes WordNet available to research and commercial users free of charge provided the terms of their license (<https://wordnet.princeton.edu/license-and-commercial-use>) are followed, and proper reference is made to the project using an appropriate citation (<https://wordnet.princeton.edu/citing-wordnet>).

Inferring causation from spatial cross-sectional data through empirical dynamic modeling (EDM), with methodological extensions including geographical convergent cross mapping from Gao et al. (2023) <doi:10.1038/s41467-023-41619-6>, geographical cross mapping cardinality as introduced by Lyu et al. (2026) <doi:10.1080/13658816.2026.2687121>, as well as the spatial causality test following the approach of Herrera et al. (2016) <doi:10.1111/pirs.12144>, together with geographical pattern causality proposed in Zhang & Wang (2025) <doi:10.1080/13658816.2025.2581207>.

Analysis of risk through liability matrices. Contains a Gibbs sampler for network reconstruction, where only row and column sums of the liabilities matrix as well as some other fixed entries are observed, following the methodology of Gandy&Veraart (2016) <doi:10.1287/mnsc.2016.2546>. It also incorporates models that use a power law distribution on the degree distribution.

Allows the creation and manipulation of C++ std::vector's in R.

Routines for the seasonal analysis of health data, including regression models, time-stratified case-crossover, plotting functions and residual checks, see Barnett and Dobson (2010) ISBN 978-3-642-10748-1. Thanks to Yuming Guo for checking the case-crossover code.