Rapid satellite data streams in operational applications have clear benefits for monitoring land cover, especially when information can be delivered as fast as changing surface conditions. Over the past decade, remote sensing has become a key tool for monitoring and predicting environmental variables by using satellite data. This package presents the main applications in remote sensing for land surface monitoring and land cover mapping (soil, vegetation, water...). Tomlinson, C.J., Chapman, L., Thornes, E., Baker, C (2011) <doi:10.1002/met.287>.

Modified functions of the package pcalg and some additional functions to run the PC and the FCI (Fast Causal Inference) algorithm for constraint-based causal discovery in incomplete and multiply imputed datasets. Foraita R, Friemel J, Günther K, Behrens T, Bullerdiek J, Nimzyk R, Ahrens W, Didelez V (2020) <doi:10.1111/rssa.12565>; Andrews RM, Bang CW, Didelez V, Witte J, Foraita R (2021) <doi:10.1093/ije/dyae113>; Witte J, Foraita R, Didelez V (2022) <doi:10.1002/sim.9535>.

Computes pseudo-realizations from the posterior distribution of a Gaussian Process (GP) with the method described in Azzimonti et al. (2016) <doi:10.1137/141000749>. The realizations are obtained from simulations of the field at few well chosen points that minimize the expected distance in measure between the true excursion set of the field and the approximate one. Also implements a R interface for (the main function of) Distance Transform of sampled Functions (<https://cs.brown.edu/people/pfelzens/dt/index.html>).

Two stage curvature identification with machine learning for causal inference in settings when instrumental variable regression is not suitable because of potentially invalid instrumental variables. Based on Guo and Buehlmann (2022) "Two Stage Curvature Identification with Machine Learning: Causal Inference with Possibly Invalid Instrumental Variables" <doi:10.48550/arXiv.2203.12808>. The vignette is available in Carl, Emmenegger, Bühlmann and Guo (2025) "TSCI: Two Stage Curvature Identification for Causal Inference with Invalid Instruments in R" <doi:10.18637/jss.v114.i07>.

Implementation of the weighted iterative proportional fitting (WIPF) procedure for updating/adjusting a N-dimensional array given a weight structure and some target marginals. Acknowledgements: The author wish to thank Conselleria de Educación, Cultura, Universidades y Empleo (grant CIAICO/2023/031), Ministerio de Ciencia, Innovación y Universidades (grant PID2021-128228NB-I00) and Fundación Mapfre (grant Modelización espacial e intra-anual de la mortalidad en España. Una herramienta automática para el cálculo de productos de vida') for supporting this research.

Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in NONMEM (non-linear mixed effects modeling) by Bauer (2019) <doi:10.1002/psp4.12404>. The package includes functions to build datasets from SDTM (study data tabulation module) <https://www.cdisc.org/standards/foundational/sdtm>, ADaM (analysis dataset module) <https://www.cdisc.org/standards/foundational/adam>, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.

This package implements the Bayesian Clustering Factor Models (BCFM) for simultaneous clustering and latent factor analysis of multivariate longitudinal data. The model accounts for within-cluster dependence through shared latent factors while allowing heterogeneity across clusters, enabling flexible covariance modeling in high-dimensional settings. Inference is performed using Markov chain Monte Carlo (MCMC) methods with computationally intensive steps implemented via Rcpp'. Model selection and visualization tools are provided. The methodology is described in Shin, Ferreira, and Tegge (2018) <doi:10.1002/sim.70350>.

Access chemical, hazard, bioactivity, and exposure data from the Computational Toxicology and Exposure ('CTX') APIs <https://api-ccte.epa.gov/docs/>. ccdR was developed to streamline the process of accessing the information available through the CTX APIs without requiring prior knowledge of how to use APIs. Most data is also available on the CompTox Chemical Dashboard ('CCD') <https://comptox.epa.gov/dashboard/> and other resources found at the EPA Computational Toxicology and Exposure Online Resources <https://www.epa.gov/comptox-tools>.

This package implements clinical tolerance limits (CTL) methodology for assessing agreement between two measurement methods. Estimates the true latent trait using Best Linear Unbiased Predictors (BLUP), models bias and variance components, and calculates overall and conditional agreement probabilities. Provides visualization tools including tolerance limit plots and conditional probability of agreement plots with confidence bands. This package is based on methods described in Taffé (2016) <doi:10.1177/0962280216666667>, Taffé (2019) <doi:10.1177/0962280219844535>, and Stata package Taffé (2025) <doi:10.1177/1536867X251365501>.

ActiGraph wGT3X-BT accelerometer processing methods using the standardized workflow developed by Statistics Canada for cycle 7 of the Canadian Health Measures Survey (CHMS). The package promotes transparent and reproducible data processing while supporting the harmonization of analytical approaches among researchers wishing to align with Statistics Canada's methods. For general details about the processing methods, please consult Clarke J, Gribbon A, St-Laurent M, Ferrao T, Barnes J, Kuzik N, Colley R (2026) <doi: 10.25318/82-003-x202600200001-eng>.

The NOIA model, as described extensively in Alvarez-Castro & Carlborg (2007), is a framework facilitating the estimation of genetic effects and genotype-to-phenotype maps. This package provides the basic tools to perform linear and multilinear regressions from real populations (provided the phenotype and the genotype of every individuals), estimating the genetic effects from different reference points, the genotypic values, and the decomposition of genetic variances in a multi-locus, 2 alleles system. This package is presented in Le Rouzic & Alvarez-Castro (2008).

This package provides a set of functions to scrape and analyze rugby data. Supports competitions including the National Rugby League, New South Wales Cup, Queensland Cup, Super League, and various representative and women's competitions. Includes functions to fetch player statistics, match results, ladders, venues, and coaching data. Designed to assist analysts, fans, and researchers in exploring historical and current rugby league data. See Woods et al. (2017) <doi:10.1123/ijspp.2016-0187> for an example of rugby league performance analysis methodology.

This package provides tools for building decision and cost-effectiveness analysis models. It enables users to write these models concisely, simulate outcomesâ including probabilistic analysesâ efficiently using optimized vectorized processes and parallel computing, and produce results. The package employs a Grammar of Modeling approach, inspired by the Grammar of Graphics, to streamline model construction. For an interactive graphical user interface, see DecisionTwig at <https://www.dashlab.ca/projects/decision_twig/>. Comprehensive tutorials and vignettes are available at <https://hjalal.github.io/twig/>.

GAGE is a published method for gene set (enrichment or GSEA) or pathway analysis. GAGE is generally applicable independent of microarray or RNA-Seq data attributes including sample sizes, experimental designs, assay platforms, and other types of heterogeneity. The gage package provides functions for basic GAGE analysis, result processing and presentation. In addition, it provides demo microarray data and commonly used gene set data based on KEGG pathways and GO terms. These functions and data are also useful for gene set analysis using other methods.

This software ADAM is a Gene set enrichment analysis (GSEA) package created to group a set of genes from comparative samples (control versus experiment) belonging to different species according to their respective functions. The corresponding roles are extracted from the default collections like Gene ontology and Kyoto encyclopedia of genes and genomes (KEGG). ADAM show their significance by calculating the p-values referring to gene diversity and activity. Each group of genes is called Group of functionally associated genes (GFAG).

This package provides functions to compute and plot Coverage Probability Excursion (CoPE) sets for real valued functions on a 2-dimensional domain. CoPE sets are obtained from repeated noisy observations of the function on the entire domain. They are designed to bound the excursion set of the target function at a given level from above and below with a predefined probability. The target function can be a parameter in spatially-indexed linear regression. Support by NIH grant R01 CA157528 is gratefully acknowledged.

Auto, Cross and Multi-dimensional recurrence quantification analysis. Different methods for computing recurrence, cross vs. multidimensional or profile iti.e., only looking at the diagonal recurrent points, as well as functions for optimization and plotting are proposed. in-depth measures of the whole cross-recurrence plot, Please refer to Coco and others (2021) <doi:10.32614/RJ-2021-062>, Coco and Dale (2014) <doi:10.3389/fpsyg.2014.00510> and Wallot (2018) <doi: 10.1080/00273171.2018.1512846> for further details about the method.

Statistical downscaling and bias correction (model output statistics) method based on cumulative distribution functions (CDF) transformation. See Michelangeli, Vrac, Loukos (2009) Probabilistic downscaling approaches: Application to wind cumulative distribution functions. Geophysical Research Letters, 36, L11708, <doi:10.1029/2009GL038401>. ; and Vrac, Drobinski, Merlo, Herrmann, Lavaysse, Li, Somot (2012) Dynamical and statistical downscaling of the French Mediterranean climate: uncertainty assessment. Nat. Hazards Earth Syst. Sci., 12, 2769-2784, www.nat-hazards-earth-syst-sci.net/12/2769/2012/, <doi:10.5194/nhess-12-2769-2012>.

Discrete-time multistate models with a user-friendly workflow. The package provides tools for processing data, several ways of estimating parametric and nonparametric multistate models, and an extensive set of Markov chain methods which use transition probabilities derived from the multistate model. Some of the implemented methods are described in Schneider et al. (2024) <doi:10.1080/00324728.2023.2176535>, Dudel (2021) <doi:10.1177/0049124118782541>, Dudel & Myrskylä (2020) <doi:10.1186/s12963-020-00217-0>, van den Hout (2017) <doi:10.1201/9781315374321>.

This package contains a set of functions that can be used to apply formats to data frames or vectors. The package aims to provide functionality similar to that of SAS® formats. Formats are assigned to the format attribute on data frame columns. Then when the fdata() function is called, a new data frame is created with the column data formatted as specified. The package also contains a value() function to create a user-defined format, similar to a SAS® user-defined format.

This package implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hersh, C.P., et al. (2017). <DOI:10.1002/gepi.22037>. Gene-based segregation method for identifying rare variants for family-based sequencing studies. Genet Epidemiol 41(4):309-319. More details can be found at <http://scholar.harvard.edu/dqiao/gese>.

This package provides functions to impute missing values using Gaussian copulas for mixed data types as described by Christoffersen et al. (2021) <arXiv:2102.02642>. The method is related to Hoff (2007) <doi:10.1214/07-AOAS107> and Zhao and Udell (2019) <arXiv:1910.12845> but differs by making a direct approximation of the log marginal likelihood using an extended version of the Fortran code created by Genz and Bretz (2002) <doi:10.1198/106186002394> in addition to also support multinomial variables.

This package provides functions that (1) fit multivariate discrete distributions, (2) generate random numbers from multivariate discrete distributions, and (3) run regression and penalized regression on the multivariate categorical response data. Implemented models include: multinomial logit model, Dirichlet multinomial model, generalized Dirichlet multinomial model, and negative multinomial model. Making the best of the minorization-maximization (MM) algorithm and Newton-Raphson method, we derive and implement stable and efficient algorithms to find the maximum likelihood estimates. On a multi-core machine, multi-threading is supported.

Six growth models are fitted using non-linear least squares. These are the Richards, the 3, 4 and 5 parameter logistic, the Gompetz and the Weibull growth models. Reference: Reddy T., Shkedy Z., van Rensburg C. J., Mwambi H., Debba P., Zuma K. and Manda, S. (2021). "Short-term real-time prediction of total number of reported COVID-19 cases and deaths in South Africa: a data driven approach". BMC medical research methodology, 21(1), 1-11. <doi:10.1186/s12874-020-01165-x>.