The main function of the package is to perform backward selection of fixed effects, forward fitting of the random effects, and post-hoc analysis using parallel capabilities. Other functionality includes the computation of ANOVAs with upper- or lower-bound p-values and R-squared values for each model term, model criticism plots, data trimming on model residuals, and data visualization. The data to run examples is contained in package LCF_data.

tidySingleCellExperiment is an adapter that abstracts the SingleCellExperiment container in the form of a tibble'. This allows *tidy* data manipulation, nesting, and plotting. For example, a tidySingleCellExperiment is directly compatible with functions from tidyverse packages `dplyr` and `tidyr`, as well as plotting with `ggplot2` and `plotly`. In addition, the package provides various utility functions specific to single-cell omics data analysis (e.g., aggregation of cell-level data to pseudobulks).

Illumina HumanWGv2 annotation data (chip illuminaHumanv2BeadID) assembled using data from public repositories to be used with data summarized from bead-level data with numeric ArrayAddressIDs as keys. Illumina probes with a No match or Bad quality score were removed prior to annotation. See http://www.compbio.group.cam.ac.uk/Resources/Annotation/index.html and Barbosa-Morais et al (2010) A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data. Nucleic Acids Research.

The idea of a computational algorithm described in the article by Andronov M. et al. (2022) <https://link.springer.com/chapter/10.1007/978-3-030-92507-9_13>. The purpose of this package is to automate computations for a Markov-Modulated M/G/1 queuing system with alternating Poisson flow of arrivals. It offers a set of functions to calculate various mean indices of the system, including mean flow intensity, mean service busy and idle times, and the system's stationary probability.

pytest-random-order is a Pytest plugin that randomizes the order of tests. This can be useful to detect a test that passes just because it happens to run after an unrelated test that leaves the system in a favourable state. The plugin allows user to control the level of randomness they want to introduce and to disable reordering on subsets of tests. Tests can be rerun in a specific order by passing a seed value reported in a previous test run.

It computes full conformal, split conformal and multi split conformal prediction regions when the response variable is multivariate (i.e. dimension is greater than one). Moreover, the package also contain plot functions to visualize the output of the full and split conformal functions. To guarantee consistency, the package structure mimics the univariate conformalInference package of professor Ryan Tibshirani. The main references for the code are: Lei et al. (2016) <arXiv:1604.04173>, Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2102.06746>, Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2106.01792>, Solari, and Djordjilovic (2021) <arXiv:2103.00627>.

The tidySummarizedExperiment package provides a set of tools for creating and manipulating tidy data representations of SummarizedExperiment objects. SummarizedExperiment is a widely used data structure in bioinformatics for storing high-throughput genomic data, such as gene expression or DNA sequencing data. The tidySummarizedExperiment package introduces a tidy framework for working with SummarizedExperiment objects. It allows users to convert their data into a tidy format, where each observation is a row and each variable is a column. This tidy representation simplifies data manipulation, integration with other tidyverse packages, and enables seamless integration with the broader ecosystem of tidy tools for data analysis.

Fits Gaussian Mixtures by applying evolution. As fitness function a mixture of the chi square test for distributions and a novel measure for approximating the common area under curves between multiple Gaussians is used. The package presents an alternative to the commonly used Likelihood Maximization as is used in Expectation Maximization. The algorithm and applications of this package are published under: Lerch, F., Ultsch, A., Lotsch, J. (2020) <doi:10.1038/s41598-020-57432-w>. The evolution is based on the GA package: Scrucca, L. (2013) <doi:10.18637/jss.v053.i04> while the Gaussian Mixture Logic stems from AdaptGauss': Ultsch, A, et al. (2015) <doi:10.3390/ijms161025897>.

Computes experimental designs for a two-arm experiment with covariates via a number of methods: (0) complete randomization and randomization with forced-balance, (1) Greedily optimizing a balance objective function via pairwise switching. This optimization provides lower variance for the treatment effect estimator (and higher power) while preserving a design that is close to complete randomization. We return all iterations of the designs for use in a permutation test, (2) The second is via numerical optimization (via gurobi which must be installed, see <https://www.gurobi.com/documentation/9.1/quickstart_windows/r_ins_the_r_package.html>) a la Bertsimas and Kallus, (3) rerandomization, (4) Karp's method for one covariate, (5) exhaustive enumeration to find the optimal solution (only for small sample sizes), (6) Binary pair matching using the nbpMatching library, (7) Binary pair matching plus design number (1) to further optimize balance, (8) Binary pair matching plus design number (3) to further optimize balance, (9) Hadamard designs, (10) Simultaneous Multiple Kernels. In (1-9) we allow for three objective functions: Mahalanobis distance, Sum of absolute differences standardized and Kernel distances via the kernlab library. This package is the result of a stream of research that can be found in Krieger, A, Azriel, D and Kapelner, A "Nearly Random Designs with Greatly Improved Balance" (2016) <arXiv:1612.02315>, Krieger, A, Azriel, D and Kapelner, A "Better Experimental Design by Hybridizing Binary Matching with Imbalance Optimization" (2021) <arXiv:2012.03330>.

u-root embodies four different projects.

Affymetrix rta10 annotation data (chip rta10transcriptcluster) assembled using data from public repositories.

This package provides proc macros for the lazy_regex crate.

This package provides proc macros for the lazy_regex crate.

This package provides an implementation of the RDF4J Rio API, which reads and writes TriG.

This package provides an Rcmdr "plug-in" based on the TeachingDemos package, and is primarily for illustrative purposes.

Generic netlink packet types.

Datasets to support COPDSexaulDimorphism Package.

Implementation for the package color-print.

This package provides Import lib for Windows.

This package provides Unicode Bidi Mirroring property detection.

This package provides Unicode Bidi Mirroring property detection.

Internal procedural macros for the stdweb crate.

Pabot is a parallel executor for Robot Framework tests.

This package provides a JavaScript grammar for tree-sitter.