Allows the user to conduct randomization-based inference for a wide variety of experimental scenarios. The package leverages a potential outcomes framework to output randomization-based p-values and null intervals for test statistics geared toward any estimands of interest, according to the specified null and alternative hypotheses. Users can define custom randomization schemes so that the randomization distributions are accurate for their experimental settings. The package also creates visualizations of randomization distributions and can test multiple test statistics simultaneously.

We provide an Rcmdr plug-in based on the depthTools package, which implements different robust statistical tools for the description and analysis of gene expression data based on the Modified Band Depth, namely, the scale curves for visualizing the dispersion of one or various groups of samples (e.g. types of tumors), a rank test to decide whether two groups of samples come from a single distribution and two methods of supervised classification techniques, the DS and TAD methods.

Perform likelihood estimation and corresponding analysis under the copula-based Markov chain model for serially dependent event times with a dependent terminal event. Available are statistical methods in Huang, Wang and Emura (2020, JJSD accepted).

An open source library for face detection in images. Provides a pretrained convolutional neural network based on <https://github.com/ShiqiYu/libfacedetection> which can be used to detect faces which have size greater than 10x10 pixels.

one-more-re-nightmare is a regular expression engine that uses the technique presented in Regular-expression derivatives re-examined (Owens, Reppy and Turon, 2009; doi:10.1017/S0956796808007090) to interpret and compile regular expressions.

implements a MsBackend for the Spectra package using Thermo Fisher Scientific's NewRawFileReader .Net libraries. The package is generalizing the functionality introduced by the rawrr package Methods defined in this package are supposed to extend the Spectra Bioconductor package.

Encodes several methods for performing Mendelian randomization analyses with summarized data. Summarized data on genetic associations with the exposure and with the outcome can be obtained from large consortia. These data can be used for obtaining causal estimates using instrumental variable methods.

Gene-level count matrix data for bulk RNA-seq dataset with many replicates. The data are provided as easy to use SummarizedExperiment objects. The source data that is made accessible through this package comes from https://github.com/bartongroup/profDGE48.

This package provides functions for interfacing with the Metabolomics Workbench RESTful API. Study, compound, protein and gene information can be searched for using the API. Methods to obtain study data in common Bioconductor formats such as SummarizedExperiment and MultiAssayExperiment are also included.

This tool set provides a set of functions to fit the nested Dirichlet process mixture of products of multinomial distributions (NDPMPM) model for nested categorical household data in the presence of impossible combinations. It has direct applications in imputing missing values for and generating synthetic versions of nested household data.

Rainbow-delimiters is a "rainbow parentheses"-like mode for Emacs which highlights parentheses, brackets, and braces according to their depth. Each successive level is highlighted in a different color, making it easy to spot matching delimiters, orient yourself in the code, and tell which statements are at a given level.

Accompanies a paper (Barunik, Krehlik (2018) <doi:10.1093/jjfinec/nby001>) dedicated to spectral decomposition of connectedness measures and their interpretation. We implement all the developed estimators as well as the historical counterparts. For more information, see the help or GitHub page (<https://github.com/tomaskrehlik/frequencyConnectedness>) for relevant information.

The datatool-regions bundle provides the language-independent region .ldf files for the datatool package. The region files deal with defining the currency symbol, and may additionally (if not dependent on the language) set the number group and decimal characters, and provide functions for parsing numeric dates and times.

Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples.

The pip-run command provides on-demand temporary package installation for a single interpreter run. It replaces this series of commands:

$ virtualenv --python pythonX.X --system-site-packages /tmp/env
$ /tmp/env/bin/pip install pkg1 pkg2 -r reqs.txt
$ /tmp/env/bin/python ...
$ rm -rf /tmp/env

This is a data package that hosts annotated sub-cellular localised datasets from the STOmics, Xenium and CosMx platforms. Specifically, it hosts datasets analysed in the publication Bhuva et. al, 2024 titled "Library size confounds biology in spatial transcriptomics data". Raw transcript detections are hosted and functions to convert them to SpatialExperiment objects have been implemented.

Make optimal decisions for your personal or household finances. Use tools and methods that are selected carefully to align with academic consensus, bridging the gap between theoretical knowledge and practical application. They help you find your own personalized optimal discretionary spending or optimal asset allocation, and prepare you for retirement or financial independence. The optimal solution to this problems is extremely complex, and we only have a single lifetime to get it right. Fortunately, we now have the user-friendly tools implemented, that integrate life-cycle models with single-period net-worth mean-variance optimization models. Those tools can be used by anyone who wants to see what highly-personalized optimal decisions can look like. For more details see: Idzorek T., Kaplan P. (2024, ISBN:9781952927379), Haghani V., White J. (2023, ISBN:9781119747918).

An outcome-guided algorithm is developed to identify clusters of samples with similar characteristics and survival rate. The algorithm first builds a random forest and then defines distances between samples based on the fitted random forest. Given the distances, we can apply hierarchical clustering algorithms to define clusters. Details about this method is described in <https://github.com/luyouepiusf/SurvivalClusteringTree>.

This package adds new RSS generation options to the org-publish-project-alist variable (see the Org manual if you are new to the publishing options). It adds :auto-rss and other options that work similar to the included :auto-sitemap functionality. This should make it easy for users to add RSS feeds to existing Org-based websites.

This module allows libraries to have a dependency to a small module instead of the full Log-Report distribution. The full power of Log::Report is only released when the main program uses that module. In that case, the module using the Optional will also use the full Log::Report, otherwise the dressed-down Log::Report::Minimal version.

This small package modifies the BibLaTeX macro which reads a .bbl file created by Biber. It is thus possible to include a .bbl file into the main document with the environment and send it to a publisher who does not need to run the Biber program. However, when the bibliography changes one has to create a new .bbl file.

This package provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database. ChEMBL has been chosen for this purpose, because it provides one of the most comprehensive and best annotatated knowledge resources for drug-target information available in the public domain.

Computes the Danish Pesticide Load Indicator as described in Kudsk et al. (2018) <doi:10.1016/j.landusepol.2017.11.010> and Moehring et al. (2019) <doi:10.1016/j.scitotenv.2018.07.287> for pesticide use data. Additionally offers the possibility to directly link pesticide use data to pesticide properties given access to the Pesticide properties database (Lewis et al., 2016) <doi:10.1080/10807039.2015.1133242>.

Genetic algorithm are a class of optimization algorithms inspired by the process of natural selection and genetics. This package is for learning purposes and allows users to optimize various functions or parameters by mimicking biological evolution processes such as selection, crossover, and mutation. Ideal for tasks like machine learning parameter tuning, mathematical function optimization, and solving an optimization problem that involves finding the best solution in a discrete space.