Efficient implementations of functions for the creation, modification and analysis of phylogenetic trees. Applications include: generation of trees with specified shapes; tree rearrangement; analysis of tree shape; rooting of trees and extraction of subtrees; calculation and depiction of split support; plotting the position of rogue taxa (Klopfstein & Spasojevic 2019) <doi:10.1371/journal.pone.0212942>; calculation of ancestor-descendant relationships, of stemwardness (Asher & Smith, 2022) <doi:10.1093/sysbio/syab072>, and of tree balance (Mir et al. 2013, Lemant et al. 2022) <doi:10.1016/j.mbs.2012.10.005>, <doi:10.1093/sysbio/syac027>; artificial extinction (Asher & Smith, 2022) <doi:10.1093/sysbio/syab072>; import and export of trees from Newick, Nexus (Maddison et al. 1997) <doi:10.1093/sysbio/46.4.590>, and TNT <https://www.lillo.org.ar/phylogeny/tnt/> formats; and analysis of splits and cladistic information.

This package implements the truncated harmonic mean estimator (THAMES) of the reciprocal marginal likelihood for uni- and multivariate mixture models using posterior samples and unnormalized log posterior values via reciprocal importance sampling. Metodiev, Irons, Perrot-Dockès, Latouche & Raftery (2025) <doi:10.48550/arXiv.2504.21812>.

Trauma Mortality prediction for ICD-9, ICD-10, and AIS lexicons in long or wide format based on Dr. Alan Cook's tmpm mortality model.

Analyse data from longitudinal studies to characterise changes in values of semi-quantitative outcome variables within individual subjects, using high performance C++ code to enable rapid processing of large datasets. A flexible methodology is available for codifying these state transitions.

Bindings for the Tabula <https://tabula.technology/> Java library, which can extract tables from PDF files. This tool can reduce time and effort in data extraction processes in fields like investigative journalism. It allows for automatic and manual table extraction, the latter facilitated through a Shiny interface, enabling manual areas selection\ with a computer mouse for data retrieval.

Features include the ability to extract tabled content from NISO-JATS-coded XML, any native HTML or HML file, DOCX, and PDF documents, and then collapse it into a text format that is readable by humans by mimicking the actions of a screen reader. As tables within PDF documents are extracted with the tabulapdf package, and the table captions and footnotes cannot be extracted, the results on tables within PDF documents have to be considered less precise. The function table2matrix() returns a list of the tables within a document as character matrices. table2text() collapses the matrix content into a list of character strings by imitating the behavior of a screen reader. The textual representation of characters and numbers can be unified with unifyMatrix() before parsing. The function table2stats() extracts the tabled statistical test results from the collapsed text with the function standardStats() from the JATSdecoder package and, if activated, checks the reported and coded p-values for consistency. Due to the great variability and potential complexity of table structures, parsing accuracy may vary. A detailed description of how tableParser works is provided here: <doi:10.48550/arXiv.2603.19756>.

This package provides a variety of tools for assessing dose response curves, with an emphasis on toxicity test data. The main feature of this package are modular functions which can be combined through the namesake pipeline, runtoxdrc', to automate the analysis for large and complex datasets. This includes optional data preprocessing steps, like outlier detection, solvent effects, blank correction, averaging technical replicates, and much more. Additionally, this pipeline is adaptable to any long form dataset, and does not require specific column or group naming to work.

Extensions to lattice', providing new high-level functions, methods for existing functions, panel functions, and a theme.

Computation of stopping boundaries for a single-arm trial using a Bayesian criterion. For each m<=n (n=total patient number of the trial) the smallest number of observed toxicities is calculated leading to the termination of the trial/accrual according to the specified criteria. The probabilities of stopping the trial/accrual at and up until (resp.) the m-th patient (m<=n) is also calculated. This design is more conservative than the frequentist approach (using Clopper Pearson CIs) which might be preferred as it concerns safety. See also Aamot et al. (2010) "Continuous monitoring of toxicity in clinical Trials - simulating the risk of stopping prematurely" <doi:10.5414/cpp48476>.

Generalization of the classification and regression tree (CART) model that partitions subjects into terminal nodes and tailors machine learning model to each terminal node.

Convert T Cell Receptor (TCR) gene names between the 10X Genomics, Adaptive Biotechnologies, and ImMunoGeneTics (IMGT) nomenclatures.

Implementation of the tree-guided feature selection and logic aggregation approach introduced in Chen et al. (2024) <doi:10.1080/01621459.2024.2326621>. The method enables the selection and aggregation of large-scale rare binary features with a known hierarchical structure using a convex, linearly-constrained regularized regression framework. The package facilitates the application of this method to both linear regression and binary classification problems by solving the optimization problem via the smoothing proximal gradient descent algorithm (Chen et al. (2012) <doi:10.1214/11-AOAS514>).

Plots ternary diagrams (simplex plots / Gibbs triangles) and Holdridge life zone plots <doi:10.1126/science.105.2727.367> using the standard graphics functions. Allows custom annotation, interpolating, contouring and scaling of plotting region. Includes a Shiny user interface for point-and-click ternary plotting. An alternative to ggtern', which uses the ggplot2 family of plotting functions.

The tdROC package facilitates the estimation of time-dependent ROC (Receiver Operating Characteristic) curves and the Area Under the time-dependent ROC Curve (AUC) in the context of survival data, accommodating scenarios with right censored data and the option to account for competing risks. In addition to the ROC/AUC estimation, the package also estimates time-dependent Brier score and survival difference. Confidence intervals of various estimated quantities can be obtained from bootstrap. The package also offers plotting functions for visualizing time-dependent ROC curves.

This package provides functions for attaching tags to R objects, searching for objects based on tags, and removing tags from objects. It also includes a function for removing all tags from an object, as well as a function for deleting all objects with a specific tag from the R environment. The package is useful for organizing and managing large collections of objects in R.

This package contains some auxiliary functions.

This package provides a collection of functions for data analysis with two-by-two contingency tables. The package provides tools to compute measures of effect (odds ratio, risk ratio, and risk difference), calculate impact numbers and attributable fractions, and perform hypothesis testing. Statistical analysis methods are oriented towards epidemiological investigation of relationships between exposures and outcomes.

Calculate the failure probability of civil engineering problems with Level I up to Level III Methods. Have fun and enjoy. References: Spaethe (1991, ISBN:3-211-82348-4) "Die Sicherheit tragender Baukonstruktionen", AU,BECK (2001) "Estimation of small failure probabilities in high dimensions by subset simulation." <doi:10.1016/S0266-8920(01)00019-4>, Breitung (1989) "Asymptotic approximations for probability integrals." <doi:10.1016/0266-8920(89)90024-6>.

It provides generic methods that are used by more than one package, avoiding conflicts. This package will be imported by tidySingleCellExperiment and tidyseurat'.

Fit Thurstonian Item Response Theory (IRT) models in R. This package supports fitting Thurstonian IRT models and its extensions using Stan', lavaan', or Mplus for the model estimation. Functionality for extracting results, making predictions, and simulating data is provided as well. References: Brown & Maydeu-Olivares (2011) <doi:10.1177/0013164410375112>; Bürkner et al. (2019) <doi:10.1177/0013164419832063>.

Handling taxonomic lists through objects of class taxlist'. This package provides functions to import species lists from Turboveg (<https://www.synbiosys.alterra.nl/turboveg/>) and the possibility to create backups from resulting R-objects. Also quick displays are implemented as summary-methods.

This package implements the tail-rank statistic for selecting biomarkers from a microarray data set, an efficient nonparametric test focused on the distributional tails. See <https://gitlab.com/krcoombes/coombeslab/-/blob/master/doc/papers/tolstoy-new.pdf>.

This package provides access to the complete Pali Canon, or Tipitaka, the canonical scripture for Theravadin Buddhists worldwide. Based on the Chattha Sangayana Tipitaka version 4 (Vipassana Research Institute, 1990). Includes word frequency data and tools for Pali string sorting. For a lemmatized critical edition with sutta-level granularity, see the companion package tipitaka.critical'.

Calculates trait moments from trait and community data using the methods developed in Maitner et al (2021) <doi:10.22541/au.162196147.76797968/v1>.