Accelerate the process from clinical data to medical publication, including clinical data cleaning, significant result screening, and the generation of publish-ready tables and figures.

Implementation of Hurst exponent estimators based on complex-valued lifting wavelet energy from Knight, M. I and Nunes, M. A. (2018) <doi:10.1007/s11222-018-9820-8>.

This package provides functions for the quality control, homogenization and missing data infilling of climatological series, and to obtain climatological summaries and grids from the results. Also functions to draw wind-roses and Walter&Lieth climate diagrams are included.

Offers tools to estimate the climate representativeness of defined areas and quantifies and analyzes its transformation under future climate change scenarios. Approaches described in Mingarro and Lobo (2018) <doi:10.32800/abc.2018.41.0333> and Mingarro and Lobo (2022) <doi:10.1017/S037689292100014X>.

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

This package provides a suite of routines for Clifford algebras, using the Map class of the Standard Template Library. Canonical reference: Hestenes (1987, ISBN 90-277-1673-0, "Clifford algebra to geometric calculus"). Special cases including Lorentz transforms, quaternion multiplication, and Grassmann algebra, are discussed. Vignettes presenting conformal geometric algebra, quaternions and split quaternions, dual numbers, and Lorentz transforms are included. The package follows disordR discipline.

Annotates data from liquid chromatography coupled to mass spectrometry (LC/MS) metabolomics experiments. Based on a network algorithm (O.Senan, A. Aguilar- Mogas, M. Navarro, O. Yanes, R.Guimerà and M. Sales-Pardo, Bioinformatics, 35(20), 2019), CliqueMS builds a weighted similarity network where nodes are features and edges are weighted according to the similarity of this features. Then it searches for the most plausible division of the similarity network into cliques (fully connected components). Finally it annotates metabolites within each clique, obtaining for each annotated metabolite the neutral mass and their features, corresponding to isotopes, ionization adducts and fragmentation adducts of that metabolite.

Includes climate data from Japan Meteorological Agency ('JMA') <https://www.jma.go.jp/jma/indexe.html>. Can download climate data from JMA'.

Classification of climate according to Koeppen - Geiger, of aridity indices, of continentality indices, of water balance after Thornthwaite, of viticultural bioclimatic indices. Drawing climographs: Thornthwaite, Peguy, Bagnouls-Gaussen.

This package provides tools to download the climatic data of the Spanish Meteorological Agency (AEMET) directly from R using their API and create scientific graphs (climate charts, trend analysis of climate time series, temperature and precipitation anomalies maps, warming stripes graphics, climatograms, etc.).

Utility functions to facilitate the import, the reporting and analysis of clinical data. Example datasets in SDTM and ADaM format, containing a subset of patients/domains from the CDISC Pilot 01 study are also available as R datasets to demonstrate the package functionalities.

Every research team have their own script for data management, statistics and most importantly hemodynamic indices. The purpose is to standardize scripts utilized in clinical research. The hemodynamic indices can be used in a long-format dataframe, and add both periods of interest (trigger-periods), and delete artifacts with deleter-files. Transfer function analysis (Claassen et al. (2016) <doi:10.1177/0271678X15626425>) and Mx (Czosnyka et al. (1996) <doi:10.1161/01.str.27.10.1829>) can be calculated using this package.

This package performs biomedical named entity recognition, Unified Medical Language System (UMLS) concept mapping, and negation detection using the Python spaCy', scispaCy', and medspaCy packages, and transforms extracted data into a wide format for inclusion in machine learning models. The development of the scispaCy package is described by Neumann (2019) <doi:10.18653/v1/W19-5034>. The medspacy package uses ConText', an algorithm for determining the context of clinical statements described by Harkema (2009) <doi:10.1016/j.jbi.2009.05.002>. Clinspacy also supports entity embeddings from scispaCy and UMLS cui2vec concept embeddings developed by Beam (2018) <arXiv:1804.01486>.

This package provides a framework that facilitates spatio-temporal analysis of climate dynamics through exploring and measuring different dimensions of climate change in space and time.

This package provides a small subset of Unicode symbols, that are useful when building command line applications. They fall back to alternatives on terminals that do not support Unicode.

Clustering categorical sequences by means of finite mixtures with Markov model components is the main utility of ClickClust. The package also allows detecting blocks of equivalent states by forward and backward state selection procedures.

Are you spending too much time fetching and managing clinical trial data? Struggling with complex queries and bulk data extraction? What if you could simplify this process with just a few lines of code? Introducing clintrialx - Fetch clinical trial data from sources like ClinicalTrials.gov <https://clinicaltrials.gov/> and the Clinical Trials Transformation Initiative - Access to Aggregate Content of ClinicalTrials.gov database <https://aact.ctti-clinicaltrials.org/>, supporting pagination and bulk downloads. Also, you can generate HTML reports based on the data obtained from the sources!

Supports analysis of trends in climate change, ecological and crop modelling.

This data package contains monthly climate data in Germany, it can be used for heating and cooling calculations (external temperature, heating / cooling days, solar radiation).

An easy and fast way to visualize and profile the high-throughput IP data. This package generates the meta gene profile and other profiles. These profiles could provide valuable information for understanding the IP experiment results.

This package provides a set of tools to read, analyze and write lists of click sequences on websites (i.e., clickstream). A click can be represented by a number, character or string. Clickstreams can be modeled as zero- (only computes occurrence probabilities), first- or higher-order Markov chains.

This package provides functions for fitting GEV and POT (via point process fitting) models for extremes in climate data, providing return values, return probabilities, and return periods for stationary and nonstationary models. Also provides differences in return values and differences in log return probabilities for contrasts of covariate values. Functions for estimating risk ratios for event attribution analyses, including uncertainty. Under the hood, many of the functions use functions from extRemes', including for fitting the statistical models. Details are given in Paciorek, Stone, and Wehner (2018) <doi:10.1016/j.wace.2018.01.002>.

API client for ClimMob', an open source software for decentralized large-N trials with the tricot approach <https://climmob.net/>. Developed by van Etten et al. (2019) <doi:10.1017/S0014479716000739>, it turns the research paradigm on its head; instead of a few researchers designing complicated trials to compare several technologies in search of the best solutions for the target environment, it enables many participants to carry out reasonably simple experiments that taken together can offer even more information. ClimMobTools enables project managers to deep explore and analyse their ClimMob data in R.

Set of tools to compute metrics and indices for climate analysis. The package provides functions to compute extreme indices, evaluate the agreement between models and combine theses models into an ensemble. Multi-model time series of climate indices can be computed either after averaging the 2-D fields from different models provided they share a common grid or by combining time series computed on the model native grid. Indices can be assigned weights and/or combined to construct new indices. The package makes use of some of the methods described in: N. Manubens et al. (2018) <doi:10.1016/j.envsoft.2018.01.018>.