timeOmics is a generic data-driven framework to integrate multi-Omics longitudinal data measured on the same biological samples and select key temporal features with strong associations within the same sample group. The main steps of timeOmics are: 1. Plaform and time-specific normalization and filtering steps; 2. Modelling each biological into one time expression profile; 3. Clustering features with the same expression profile over time; 4. Post-hoc validation step.

Timed references for imperative state. This module provides an alternative type for references (or mutable cells) supporting undo/redo operations. In particular, an abstract notion of time is used to capture the state of the references at any given point, so that it can be restored. Note that usual reference operations only have a constant time / memory overhead (compared to those of the standard library).

Moreover, we provide an alternative implementation based on the references of the standard library (Pervasives module). However, it is less efficient than the first one.

Objects to manipulate sequential and seasonal time series. Sequential time series based on time instants and time duration are handled. Both can be regularly or unevenly spaced (overlapping duration are allowed). Only POSIX* format are used for dates and times. The following classes are provided : POSIXcti', POSIXctp', TimeIntervalDataFrame', TimeInstantDataFrame', SubtimeDataFrame ; methods to switch from a class to another and to modify the time support of series (hourly time series to daily time series for instance) are also defined. Tools provided can be used for instance to handle environmental monitoring data (not always produced on a regular time base).

Estimates time varying regression effects under Cox type models in survival data using classification and regression tree. The codes in this package were originally written in S-Plus for the paper "Survival Analysis with Time-Varying Regression Effects Using a Tree-Based Approach," by Xu, R. and Adak, S. (2002) <doi:10.1111/j.0006-341X.2002.00305.x>, Biometrics, 58: 305-315. Development of this package was supported by NIH grants AG053983 and AG057707, and by the UCSD Altman Translational Research Institute, NIH grant UL1TR001442. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The example data are from the Honolulu Heart Program/Honolulu Asia Aging Study (HHP/HAAS).

TimeScape is an automated tool for navigating temporal clonal evolution data. The key attributes of this implementation involve the enumeration of clones, their evolutionary relationships and their shifting dynamics over time. TimeScape requires two inputs: (i) the clonal phylogeny and (ii) the clonal prevalences. Optionally, TimeScape accepts a data table of targeted mutations observed in each clone and their allele prevalences over time. The output is the TimeScape plot showing clonal prevalence vertically, time horizontally, and the plot height optionally encoding tumour volume during tumour-shrinking events. At each sampling time point (denoted by a faint white line), the height of each clone accurately reflects its proportionate prevalence. These prevalences form the anchors for bezier curves that visually represent the dynamic transitions between time points.

We provide a toolbox to estimate the time delay between the brightness time series of gravitationally lensed quasar images via Bayesian and profile likelihood approaches. The model is based on a state-space representation for irregularly observed time series data generated from a latent continuous-time Ornstein-Uhlenbeck process. Our Bayesian method adopts scientifically motivated hyper-prior distributions and a Metropolis-Hastings within Gibbs sampler, producing posterior samples of the model parameters that include the time delay. A profile likelihood of the time delay is a simple approximation to the marginal posterior distribution of the time delay. Both Bayesian and profile likelihood approaches complement each other, producing almost identical results; the Bayesian way is more principled but the profile likelihood is easier to implement. A new functionality is added in version 1.0.9 for estimating the time delay between doubly-lensed light curves observed in two bands. See also Tak et al. (2017) <doi:10.1214/17-AOAS1027>, Tak et al. (2018) <doi:10.1080/10618600.2017.1415911>, Hu and Tak (2020) <arXiv:2005.08049>.

This package provides a Windows file time library.

This package provides a Rust interface to the Linux kernel's timerfd API.

This package provides functions for data analysis and graphical displays for developmental microarray time course data.

Supplementary Data package for tandem timer methods paper by Barry et al. (2015) including TimerQuant shiny applications.

This package provides a time formatting library in Rust that converts durations into strings. For example, "1 hour ago" or "01hou".

Timeout provides a way to auto-terminate a potentially long-running operation if it hasn't finished in a fixed amount of time.

Generate weekly timetables as a ggplot2 layer. Add informative timeslots with elements such as title, key-value pairs, or colour to reveal trends.

This package implements S4 classes and various tools for financial time series. Basic functions such as scaling and sorting, subsetting, mathematical operations and statistical functions are provided.

Old-time is a package for backwards compatibility with the old time library. For new projects, the newer time library is recommended.

Timecop provides "time travel" and "time freezing" capabilities, making it easier to test time-dependent code. It provides a unified method to mock Time.now, Date.today, and DateTime.now in a single call.

The Non Timeline is a powerful, reliable and fast modular digital audio timeline arranger. It utilizes JACK for inter-application audio I/O and the NTK GUI toolkit for a fast and lightweight user interface. Non Timeline can be used alone or in concert with Non Mixer and Non Sequencer to form a complete studio.

This package provides efficient routines for manipulation of date-time objects while accounting for time-zones and daylight saving times. The package includes utilities for updating of date-time components (year, month, day etc.), modification of time-zones, rounding of date-times, period addition and subtraction etc. Parts of the CCTZ source code, released under the Apache 2.0 License, are included in this package.

Unleash the power of time-series data visualization with ease using our package. Designed with simplicity in mind, it offers three key features through the shiny package output. The first tab shows time- series charts with forecasts, allowing users to visualize trends and changes effortlessly. The second one displays Averages per country presented in tables with accompanying sparklines, providing a quick and attractive overview of the data. The last tab presents A customizable world map colored based on user-defined variables for any chosen number of countries, offering an advanced visual approach to understanding geographical data distributions. This package operates with just a few simple arguments, enabling users to conduct sophisticated analyses without the need for complex programming skills. Transform your time-series data analysis experience with our user-friendly tool.

Infer constant and stochastic, time-dependent parameters to consider intrinsic stochasticity of a dynamic model and/or to analyze model structure modifications that could reduce model deficits. The concept is based on inferring time-dependent parameters as stochastic processes in the form of Ornstein-Uhlenbeck processes jointly with inferring constant model parameters and parameters of the Ornstein-Uhlenbeck processes. The package also contains functions to sample from and calculate densities of Ornstein-Uhlenbeck processes. References: Tomassini, L., Reichert, P., Kuensch, H.-R. Buser, C., Knutti, R. and Borsuk, M.E. (2009), A smoothing algorithm for estimating stochastic, continuous-time model parameters and its application to a simple climate model, Journal of the Royal Statistical Society: Series C (Applied Statistics) 58, 679-704, <doi:10.1111/j.1467-9876.2009.00678.x> Reichert, P., and Mieleitner, J. (2009), Analyzing input and structural uncertainty of nonlinear dynamic models with stochastic, time-dependent parameters. Water Resources Research, 45, W10402, <doi:10.1029/2009WR007814> Reichert, P., Ammann, L. and Fenicia, F. (2021), Potential and challenges of investigating intrinsic uncertainty of hydrological models with time-dependent, stochastic parameters. Water Resources Research 57(8), e2020WR028311, <doi:10.1029/2020WR028311> Reichert, P. (2022), timedeppar: An R package for inferring stochastic, time-dependent model parameters, in preparation.

Small crate that provides CPU time measurement.

Run the supplied function exactly one time (once)

Run the supplied function exactly one time (once).

This package provides a timeout mechanism for unit tests.