`tidyCoverage` framework enables tidy manipulation of collections of genomic tracks and features using `tidySummarizedExperiment` methods. It facilitates the extraction, aggregation and visualization of genomic coverage over individual or thousands of genomic loci, relying on `CoverageExperiment` and `AggregatedCoverage` classes. This accelerates the integration of genomic track data in genomic analysis workflows.

This package implements a method to rapidly assess cell type identity using both functional and random gene sets and it allows users to quantify cell type replicability across datasets using neighbor voting. MetaNeighbor works on the basis that cells of the same type should have more similar gene expression profiles than cells of different types.

This package is designed to improve and simplify the analysis of scRNA-seq data. It uses the Seurat object for this purpose. It provides an array of enhanced visualization tools, an integrated functional and pathway analysis pipeline, seamless integration with popular Python tools, and a suite of utility functions to aid in data manipulation and presentation.

mkmf-lite is a light version of Ruby's mkmf.rb designed for use as a library. It does not create packages, builds, or log files of any kind. Instead, it provides mixin methods that you can use in FFI or tests to check for the presence of header files, constants, and so on.

Record your test suite's HTTP interactions and replay them during future test runs for fast, deterministic, accurate tests. This is an older version of VCR that is free software under the Expat license. The project later switched to the Hippocratic license, which is non-free. Do not use it in new free software projects.

This package aims to quantify and remove putative double strand DNA from a strand-specific RNA sample. There are also options and methods to plot the positive/negative proportions of all sliding windows, which allow users to have an idea of how much the sample was contaminated and the appropriate threshold to be used for filtering.

This package provides tools that can be used to calculate, evaluate, plot and use for inference the profiles of *arbitrary* inference functions for arbitrary glm-like fitted models with linear predictors. More information on the methods that are implemented can be found in Kosmidis (2008) https://www.r-project.org/doc/Rnews/Rnews_2008-2.pdf.

The rencode module is a data structure serialization library, similar to bencode from the BitTorrent project. For complex, heterogeneous data structures with many small elements, r-encoding stake up significantly less space than b-encodings. This version of rencode is a complete rewrite in Cython to attempt to increase the performance over the pure Python module.

This packages provides a flexible, fast and accurate method for targeted pre-processing of GC-MS data. The user provides a (often very large) set of GC chromatograms and a metabolite library of targets. The package will automatically search those targets in the chromatograms resulting in a data matrix that can be used for further data analysis.

This package provides functions to convert a page of plots drawn with the graphics package into identical output drawn with the grid package. The result looks like the original graphics-based plot, but consists of grid grobs and viewports that can then be manipulated with grid functions (e.g., edit grobs and revisit viewports).

inf-ruby provides a Read Eval Print Loop (REPL) buffer, allowing for easy interaction with a Ruby subprocess. Features include support for detecting specific uses of Ruby, e.g., when using Rails, and using an appropriate console.

If you are using Guix shell with manifest.scm, the inf-ruby-wrapper-command customization variable could be helpful.

The objective of this package is to efficiently create scatterplots where groups can be distinguished by color and texture. Visualizations in computational biology tend to have many groups making it difficult to distinguish between groups solely on color. Thus, this package is useful for increasing the accessibility of scatterplot visualizations to those with visual impairments such as color blindness.

This package provides Bioconductor-friendly wrappers for RNA velocity calculations in single-cell RNA-seq data. We use the basilisk package to manage Conda environments, and the zellkonverter package to convert data structures between SingleCellExperiment (R) and AnnData (Python). The information produced by the velocity methods is stored in the various components of the SingleCellExperiment class.

This package provides an SQL-based mass spectrometry (MS) data backend supporting also storage and handling of very large data sets. Objects from this package are supposed to be used with the Spectra Bioconductor package. Through the MsBackendSql with its minimal memory footprint, this package thus provides an alternative MS data representation for very large or remote MS data sets.

The r-abhgenotyper package provides simple imputation, error-correction and plotting capacities for genotype data. The package is supposed to serve as an intermediate but independent analysis tool between the TASSEL GBS pipeline and the r-qtl package. It provides functionalities not found in either TASSEL or r-qtl in addition to visualization of genotypes as "graphical genotypes".

SpaceTrooper performs Quality Control analysis using data driven GLM models of Image-Based spatial data, providing exploration plots, QC metrics computation, outlier detection. It implements a GLM strategy for the detection of low quality cells in imaging-based spatial data (Transcriptomics and Proteomics). It additionally implements several plots for the visualization of imaging based polygons through the ggplot2 package.

EASY-ROUTES is yet another routes handling system on top of Hunchentoot. It's just glue code for Restas routing subsystem (CL-ROUTES).

It supports:

• dispatch based on HTTP method

• arguments extraction from the url path

• decorators

• URL generation from route names

This package provides EASY-ROUTES, EASY-ROUTES+DJULA and EASY-ROUTES+ERRORS systems.

mirTarRnaSeq R package can be used for interactive mRNA miRNA sequencing statistical analysis. This package utilizes expression or differential expression mRNA and miRNA sequencing results and performs interactive correlation and various GLMs (Regular GLM, Multivariate GLM, and Interaction GLMs ) analysis between mRNA and miRNA expriments. These experiments can be time point experiments, and or condition expriments.

Spatial transcriptomic technologies have helped to resolve the connection between gene expression and the 2D orientation of tissues relative to each other. However, the limited single-cell resolution makes it difficult to highlight the most important molecular interactions in these tissues. SpaceMarkers, R/Bioconductor software, can help to find molecular interactions, by identifying genes associated with latent space interactions in spatial transcriptomics.

This package provides a statistical method to impute the missing values in accelerometer data. The methodology includes both parametric and semi-parametric multiple imputations under the zero-inflated Poisson lognormal model. It also provides multiple functions to preprocess the accelerometer data previous to the missing data imputation. These include detecting the wearing and the non-wearing time, selecting valid days and subjects, and creating plots.

The tuberculosis R/Bioconductor package features tuberculosis gene expression data for machine learning. All human samples from GEO that did not come from cell lines, were not taken postmortem, and did not feature recombination have been included. The package has more than 10,000 samples from both microarray and sequencing studies that have been processed from raw data through a hyper-standardized, reproducible pipeline.

This is an implementation of the Future API on top of the callr package. This allows you to process futures, as defined by the future package, in parallel out of the box, on your local machine. Contrary to backends relying on the parallel package (e.g. future::multisession) and socket connections, the callr backend provided here can run more than 125 parallel R processes.

NetPathMiner is a general framework for network path mining using genome-scale networks. It constructs networks from KGML, SBML and BioPAX files, providing three network representations, metabolic, reaction and gene representations. NetPathMiner finds active paths and applies machine learning methods to summarize found paths for easy interpretation. It also provides static and interactive visualizations of networks and paths to aid manual investigation.

Ray is a unified framework for scaling AI and Python applications. Ray consists of a core distributed runtime and a set of AI libraries for simplifying ML compute. These are the provided Ray AI libraries:

• Data: Scalable datasets for ML;

• Train: Distributed training;

• Tune: Scalable hyperparameter tuning;

• RLlib: Scalable reinforcement learning;

• Serve: Scalable and programmable serving.