Calculates a cumulative summation nonparametric extended median test based on the work of Brown & Schaffer (2020) <DOI:10.1080/03610926.2020.1738492>. It then generates a control chart to assess processes and determine if any streams are out of control.
Evaluates the Owen Q-function for an integer value of the degrees of freedom, by applying Owen's algorithm (1965) <doi:10.1093/biomet/52.3-4.437>. It is useful for the calculation of the power of equivalence tests.
Grows a qualitative interaction tree. Quint is a tool for subgroup analysis, suitable for data from a two-arm randomized controlled trial. More information in Dusseldorp, E., Doove, L., & Van Mechelen, I. (2016) <doi:10.3758/s13428-015-0594-z>.
This package provides a covariance estimator for multivariate normal data that is sparse and positive definite. Implements the majorize-minimize algorithm described in Bien, J., and Tibshirani, R. (2011), "Sparse Estimation of a Covariance Matrix," Biometrika. 98(4). 807--820.
Code and data for modelling and simulation of stochastic kinetic biochemical network models. It contains the code and data associated with the second and third editions of the book Stochastic Modelling for Systems Biology, published by Chapman & Hall/CRC Press.
This package provides a general, tidyverse'-friendly framework for simulation studies, design analysis, and power analysis. Specify data generation, define varying parameters, generate data, fit models, and tidy model results in a single pipeline, without needing loops or custom functions.
This package provides a tool to obtain tumor growth rates from clinical trial patient data. Output includes individual and summary data for tumor growth rate estimates as well as optional plots of the observed and predicted tumor quantity over time.
This package provides various commonly-used response time trimming methods, including the recursive / moving-criterion methods reported by Van Selst and Jolicoeur (1994). By passing trimming functions raw data files, the package will return trimmed data ready for inferential testing.
This package provides a type system for R. It supports setting variable types in a script or the body of a function, so variables can't be assigned illegal values. Moreover it supports setting argument and return types for functions.
Two Phase I designs are implemented in the package: the classical 3+3 and the Continual Reassessment Method (<doi:10.2307/2531628>). Simulations tools are also available to estimate the operating characteristics of the methods with several user-dependent options.
Compared with the similar graph embedding method such as Laplacian Eigenmaps, Vicus can exploit more local structures of graph data. For the details of the methods, see the reference section of GitHub README.md <https://github.com/rikenbit/Vicus>.
Makes available code necessary to reproduce figures and tables in papers on the WaveD method for wavelet deconvolution of noisy signals as presented in The WaveD Transform in R, Journal of Statistical Software Volume 21, No. 3, 2007.
Identification of diferentially methylated regions (DMRs) in predefined regions (promoters, CpG islands...) from the human genome using Illumina's 450K or EPIC microarray data. Provides methods to rank CpG probes based on linear models and includes plotting functions.
The purpose of ncGTW is to help XCMS for LC-MS data alignment. Currently, ncGTW can detect the misaligned feature groups by XCMS, and the user can choose to realign these feature groups by ncGTW or not.
This package is designed to uncover the intrinsic cell progression path from single-cell RNA-seq data. It incorporates data pre-processing, preliminary PCA gene selection, preliminary cell ordering, feature selection, refined cell ordering, and post-analysis interpretation and visualization.
The topGO package provides tools for testing gene ontology (GO) terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied.
The biglm package lets you create a linear model object that uses only codep^2 memory for p variables. It can be updated with more data using update. This allows linear regression on data sets larger than memory.
This package provides support for measurement units in R vectors, matrices and arrays: automatic propagation, conversion, derivation and simplification of units; raising errors in case of unit incompatibility. It is compatible with the POSIXct, Date and difftime classes.
This package lets you build regression models using the techniques in Friedman's papers "Fast MARS" and "Multivariate Adaptive Regression Splines" <doi:10.1214/aos/1176347963>. The term "MARS" is trademarked and thus not used in the name of the package.
This package enables variogram modelling, including: simple, ordinary and universal point or block (co)kriging; spatio-temporal kriging; and sequential Gaussian or indicator (co)simulation. It includes variogram and variogram map plotting utility functions, and supports sf and stars.
This tool generates high number of both single- and multi-objective test functions. These functions are frequently used for the benchmarking of (numerical) optimization algorithms. Moreover, it offers a set of convenient functions to generate, plot and work with objective functions.
This package provides R6 abstract classes for building machine learning models with a scikit-learn like API. Scikit-learn is a popular module for the Python programming language whose design became a de facto standard in industry for machine learning tasks.
Root Expected Proportion Squared Difference (REPSD) is a nonparametric differential item functioning (DIF) method that (a) allows practitioners to explore for DIF related to small, fine-grained focal groups of examinees, and (b) compares the focal group directly to the composite group that will be used to develop the reported test score scale. Using your provided response matrix with a column that identifies focal group membership, this package provides the REPSD values, a simulated null distribution of possible REPSD values, and the simulated p-values identifying items possibly displaying DIF without requiring enormous sample sizes.
Analysis of gene expression RNA-seq data using Bartlett-Adjusted Likelihood-based LInear model (BALLI). Based on likelihood ratio test, it provides comparisons for effect of one or more variables. See Kyungtaek Park (2018) <doi:10.1101/344929> for more information.