Given a protein multiple sequence alignment, it is a daunting task to assess the effects of substitutions along sequence length. The aaSEA package is intended to help researchers to rapidly analyze property changes caused by single, multiple and correlated amino acid substitutions in proteins.

This package provides functions for fitting and plotting SITAR growth curve models. SITAR is a shape- invariant model with a regression B-spline mean curve and subject-specific random effects on both the measurement and age scales.

Converts data to STL (stereolithography) files that can be used to feed a 3-dimensional printer. The 3-dimensional output from a function can be materialized into a solid surface in a plastic material, therefore allowing more detailed examination. There are many possible uses for this new tool, such as to examine mathematical expressions with very irregular shapes, to aid teaching people with impaired vision, to create raised relief maps from digital elevation maps (DEMs), to bridge the gap between mathematical tools and rapid prototyping, and many more. Ian Walker created the function r2stl() and Jose Gama assembled the package.

The goal of Rigma is to provide a user friendly client to the Figma API <https://www.figma.com/developers/api>. It uses the latest `httr2` for a stable interface with the REST API. More than 20 methods are provided to interact with Figma files, and teams. Get design data into R by reading published components and styles, converting and downloading images, getting access to the full Figma file as a hierarchical data structure, and much more. Enhance your creativity and streamline the application development by automating the extraction, transformation, and loading of design data to your applications and HTML documents.

Biodiversity is in crisis. The overarching aim of conservation is to preserve biodiversity patterns and processes. To this end, protected areas are established to buffer species and preserve biodiversity processes. But resources are limited and so protected areas must be cost-effective. This package contains tools to generate plans for protected areas (prioritizations), using spatially explicit targets for biodiversity patterns and processes. To obtain solutions in a feasible amount of time, this package uses the commercial Gurobi software (obtained from <https://www.gurobi.com/>). For more information on using this package, see Hanson et al. (2018) <doi:10.1111/2041-210X.12862>.

The Cancer Genome Atlas (TCGA) Data Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA. It contains clinical information, genomic characterization data, and high level sequence analysis of the tumor genomes. The key is to understand genomics to improve cancer care. RTCGA package offers download and integration of the variety and volume of TCGA data using patient barcode key, what enables easier data possession. This may have an benefcial infuence on impact on development of science and improvement of patients treatment. Furthermore, RTCGA package transforms TCGA data to tidy form which is convenient to use.

Roswell has now evolved into a full-stack environment for Common Lisp development, and has many features that makes it easy to test, share, and distribute your Lisp applications. With Roswell, we aim to push the Common Lisp community to a whole new level of productivity.

Computing and visualizing comparative asymptotic timings of different algorithms and code versions. Also includes functionality for comparing empirical timings with expected references such as linear or quadratic, <https://en.wikipedia.org/wiki/Asymptotic_computational_complexity> Also includes functionality for measuring asymptotic memory and other quantities.

This package provides functions required to classify subjects within camera trap field data. The package can handle both images and videos. The authors recommend a two-step approach using Microsoft's MegaDector model and then a second model trained on the classes of interest.

This package provides an interface to the algorithm selection benchmark library at <http://www.aslib.net> and the LLAMA package (<https://cran.r-project.org/package=llama>) for building algorithm selection models; see Bischl et al. (2016) <doi:10.1016/j.artint.2016.04.003>.

This package provides tools designed to make it easier for beginner and intermediate users to build and validate binary logistic regression models. Includes bivariate analysis, comprehensive regression output, model fit statistics, variable selection procedures, model validation techniques and a shiny app for interactive model building.

This package provides a bootstrap-based approach to integrate multiple forms of high dimensional genomic data with multiple clinical endpoints. This method is used to find clinically meaningful groups of genomic features, such as genes or pathways. A manuscript describing this method is in preparation.

Implementation of the CNAIM standard in R. Contains a series of algorithms which determine the probability of failure, consequences of failure and monetary risk associated with electricity distribution companies assets such as transformers and cables. Results are visualized in an easy-to-understand risk matrix.

Computes the double bootstrap as discussed in McKnight, McKean, and Huitema (2000) <doi:10.1037/1082-989X.5.1.87>. The double bootstrap method provides a better fit for a linear model with autoregressive errors than ARIMA when the sample size is small.

Includes various functions for playing drum sounds. beat() plays a drum sound from one of the six included drum kits. tempo() sets spacing between calls to beat() in bpm. Together the two functions can be used to create many different drum patterns.

An R interface to the codediff JavaScript library (a copy of which is included in the package, see <https://github.com/danvk/codediff.js> for information). Allows for visualization of the difference between 2 files, usually text files or R scripts, in a browser.

Includes several statistical methods for the estimation of parameters and high quantiles of river flow distributions. The focus is on regional estimation based on homogeneity assumptions and computed from multivariate observations (multiple measurement stations). For details see Kinsvater et al. (2017) <arXiv:1701.06455>.

This package provides a model-independent factor importance ranking and selection procedure that is based on total Sobol indices. Please see Huang and Joseph (2024) <arXiv:2401.00800>. This research is supported by U.S. National Science Foundation grants DMS-2310637 and DMREF-1921873.

FDR functions for permutation-based estimators, including pi0 as well as FDR confidence intervals. The confidence intervals account for dependencies between tests by the incorporation of an overdispersion parameter, which is estimated from the permuted data. Also included are options for an analog parametric approach.

Performing the different steps of gene set enrichment meta-analysis. It provides different functions that allow the application of meta-analysis based on the combination of effect sizes from different pathways in different studies to obtain significant pathways that are common to all of them.

This package provides functions for obtaining generalized normal/exponential power distribution probabilities, quantiles, densities and random deviates. The generalized normal/exponential power distribution was introduced by Subbotin (1923) and rediscovered by Nadarajah (2005). The parametrization given by Nadarajah (2005) <doi:10.1080/02664760500079464> is used.

Network meta-analyses (mixed treatment comparisons) in the Bayesian framework using JAGS. Includes methods to assess heterogeneity and inconsistency, and a number of standard visualizations. van Valkenhoef et al. (2012) <doi:10.1002/jrsm.1054>; van Valkenhoef et al. (2015) <doi:10.1002/jrsm.1167>.

Mediation analysis is used to identify and quantify intermediate effects from factors that intervene the observed relationship between an exposure/predicting variable and an outcome. We use a Bayesian adaptive lasso method to take care of the hierarchical structures and high dimensional exposures or mediators.

An open-source R package to deploys reproducible and flexible labels using layers. The huito package is part of the inkaverse project for developing different procedures and tools used in plant science and experimental designs. Learn more about the inkaverse project at <https://inkaverse.com/>.