This package enables variogram modelling, including: simple, ordinary and universal point or block (co)kriging; spatio-temporal kriging; and sequential Gaussian or indicator (co)simulation. It includes variogram and variogram map plotting utility functions, and supports sf and stars.

Identification of diferentially methylated regions (DMRs) in predefined regions (promoters, CpG islands...) from the human genome using Illumina's 450K or EPIC microarray data. Provides methods to rank CpG probes based on linear models and includes plotting functions.

The purpose of ncGTW is to help XCMS for LC-MS data alignment. Currently, ncGTW can detect the misaligned feature groups by XCMS, and the user can choose to realign these feature groups by ncGTW or not.

This package is designed to uncover the intrinsic cell progression path from single-cell RNA-seq data. It incorporates data pre-processing, preliminary PCA gene selection, preliminary cell ordering, feature selection, refined cell ordering, and post-analysis interpretation and visualization.

Amyloid propensity prediction neural network (APPNN) is an amyloidogenicity propensity predictor based on a machine learning approach through recursive feature selection and feed-forward neural networks, taking advantage of newly published sequences with experimental, in vitro, evidence of amyloid formation.

This package provides a wrapper around the Blat command line SMTP mailer for Windows. Blat is public domain software, but be sure to read the license before use. It can be found at the Blat website http://www.blat.net.

Generate mean and median weighted or unweighted spatial centers. Functions are analogous to their identically named counterparts within ArcGIS Pro'. Median center methodology based off of Kuhn and Kuenne (1962) <doi:10.1111/j.1467-9787.1962.tb00902.x>.

The concept of cause-deleted life expectancy improvement is statistic designed to quantify the increase in life expectancy if a certain cause of death is removed. See Adamic, P. (2015) (<https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2689352>).

Tables summarizing clinical trial results are often complex and require detailed tailoring prior to submission to a health authority. The crane package supplements the functionality of the gtsummary package for creating these often highly bespoke tables in the pharmaceutical industry.

By overloading the R help() function, this package allows users to use "docstring" style comments within their own defined functions. The package also provides additional functions to mimic the R basic example() function and the prototyping of packages.

Calculation of Evapotranspiration by FAO Penman-Monteith equation based on Allen, R. G., Pereira, L. S., Raes, D., Smith, M. (1998, ISBN:92-5-104219-5) "Crop evapotranspiration - Guidelines for computing crop water requirements - FAO Irrigation and drainage paper 56".

This package implements the new algorithm for fast computation of M-scatter matrices using a partial Newton-Raphson procedure for several estimators. The algorithm is described in Duembgen, Nordhausen and Schuhmacher (2016) <doi:10.1016/j.jmva.2015.11.009>.

Sets up and executes a HiSSE model (Hidden State Speciation and Extinction) on a phylogeny and character sets to test for hidden shifts in trait dependent rates of diversification. Beaulieu and O'Meara (2016) <doi:10.1093/sysbio/syw022>.

Simplifies the whole process of creating stacked tilted maps, that are often used in scientific publications to show different environmental layers for a geographical region. Tilting maps and layering them allows to easily draw visual correlations between these environmental layers.

Bending non-positive-definite (symmetric) matrices to positive-definite, using weighted and unweighted methods. Jorjani, H., et al. (2003) <doi:10.3168/jds.S0022-0302(03)73646-7>. Schaeffer, L. R. (2014) <http://animalbiosciences.uoguelph.ca/~lrs/ELARES/PDforce.pdf>.

Determines single or multiple modes (most frequent values). Checks if missing values make this impossible, and returns NA in this case. Dependency-free source code. See Franzese and Iuliano (2019) <doi:10.1016/B978-0-12-809633-8.20354-3>.

Calculates a cumulative summation nonparametric extended median test based on the work of Brown & Schaffer (2020) <DOI:10.1080/03610926.2020.1738492>. It then generates a control chart to assess processes and determine if any streams are out of control.

Evaluates the Owen Q-function for an integer value of the degrees of freedom, by applying Owen's algorithm (1965) <doi:10.1093/biomet/52.3-4.437>. It is useful for the calculation of the power of equivalence tests.

Programmatic access to microdata from Colombia's Gran Encuesta Integrada de Hogares ('GEIH'), published by DANE'. Provides a tidy interface to download, parse, and harmonize labor market surveys from 2007 to present. R companion to the pulso-co Python package.

Grows a qualitative interaction tree. Quint is a tool for subgroup analysis, suitable for data from a two-arm randomized controlled trial. More information in Dusseldorp, E., Doove, L., & Van Mechelen, I. (2016) <doi:10.3758/s13428-015-0594-z>.

Wraps the rstac package with a pipe-friendly, tidy API. All results return tibbles instead of nested lists. Ships with a catalog registry of known STAC endpoints including Planetary Computer, Earth Search, and USGS', while supporting any STAC API URL.

This package provides a covariance estimator for multivariate normal data that is sparse and positive definite. Implements the majorize-minimize algorithm described in Bien, J., and Tibshirani, R. (2011), "Sparse Estimation of a Covariance Matrix," Biometrika. 98(4). 807--820.

Code and data for modelling and simulation of stochastic kinetic biochemical network models. It contains the code and data associated with the second and third editions of the book Stochastic Modelling for Systems Biology, published by Chapman & Hall/CRC Press.

Meta-analysis via Approximate Bayesian Computation Sequential Monte Carlo (ABC-SMC) by simulating pseudo-individual data from published group-level summary statistics. Handles binary, continuous, and generic effect-size outcomes within a one-stage mixed-model framework. Supports subgroup analysis.