This package provides tools for conducting epigenome-wide association studies (EWAS) and visualizing results. Users provide sample metadata and methylation matrices to run EWAS with linear models, linear mixed-effects models, or Cox models. The package supports downstream visualization, bootstrap validation, enrichment analysis, batch effect correction, and differentially methylated region (DMR) analysis with optional parallel computing. Methods are described in Wang et al. (2025) <doi:10.1093/bioadv/vbaf026>, Johnson et al. (2007) <doi:10.1093/biostatistics/kxj037>, and Peters et al. (2015) <doi:10.1186/1756-8935-8-6>.

In personalized medicine, one wants to know, for a given patient and his or her outcome for a predictor (pre-treatment variable), how likely it is that a treatment will be more beneficial than an alternative treatment. This package allows for the quantification of the predictive causal association (i.e., the association between the predictor variable and the individual causal effect of the treatment) and related metrics. Part of this software has been developed using funding provided from the European Union's 7th Framework Programme for research, technological development and demonstration under Grant Agreement no 602552.

This package provides a goodness-of-fit test for elliptical distributions with diagnostic capabilities. Gilles R. Ducharme, Pierre Lafaye de Micheaux (2020) <doi:10.1016/j.jmva.2020.104602>.

This package provides functions and data sets to perform and demonstrate community ecology statistical tests, including Hutcheson's t-test (Hutcheson (1970) <doi:10.1016/0022-5193(70)90124-4>, Zar (2010) ISBN:9780321656865).

Uses data and constants to calculate potential evapotranspiration (PET) and actual evapotranspiration (AET) from 21 different formulations including Penman, Penman-Monteith FAO 56, Priestley-Taylor and Morton formulations.

Set of tools to simplify application of atomic forecast verification metrics for (comparative) verification of ensemble forecasts to large data sets. The forecast metrics are imported from the SpecsVerification package, and additional forecast metrics are provided with this package. Alternatively, new user-defined forecast scores can be implemented using the example scores provided and applied using the functionality of this package.

This package produces diversity estimates and species lists with associated global distribution for any vascular plant family and genus from Plants of the World Online database <https://powo.science.kew.org/>, by interacting with the source code of each plant taxon page. It also creates global maps of species richness, graphics of species discoveries and name changes over time. For more details: Zuanny, D.C., B.Vilela, P.W.Moonlight, T.E.Särkinen, and D.Cardoso. 2024. expowo: An R package for mining global plant diversity and distribution data. Applications in Plant Sciences 12: e11609'.

Simulate and fitting exponential multivariate Hawkes model. This package simulates a multivariate Hawkes model, introduced by Hawkes (1971) <doi:10.2307/2334319>, with an exponential kernel and fits the parameters from the data. Models with the constant parameters, as well as complex dependent structures, can also be simulated and estimated. The estimation is based on the maximum likelihood method, introduced by introduced by Ozaki (1979) <doi:10.1007/BF02480272>, with maxLik package.

Notice: The package EffectStars2 provides a more up-to-date implementation of effect stars! EffectStars provides functions to visualize regression models with categorical response as proposed by Tutz and Schauberger (2013) <doi:10.1080/10618600.2012.701379>. The effects of the variables are plotted with star plots in order to allow for an optical impression of the fitted model.

Package provides a set of tools for robust estimation and inference for probit model with endogenous covariates. The current version contains a robust two-step estimator. For technical details, see Naghi, Varadi and Zhelonkin (2022), <doi:10.1016/j.ecosta.2022.05.001>.

This package contains logic for computing sparse principal components via the EESPCA method, which is based on an approximation of the eigenvector/eigenvalue identity. Includes logic to support execution of the TPower and rifle sparse PCA methods, as well as logic to estimate the sparsity parameters used by EESPCA, TPower and rifle via cross-validation to minimize the out-of-sample reconstruction error. H. Robert Frost (2021) <doi:10.1080/10618600.2021.1987254>.

Read in and analyze functions for education survey and assessment data from the National Center for Education Statistics (NCES) <https://nces.ed.gov/>, including National Assessment of Educational Progress (NAEP) data <https://nces.ed.gov/nationsreportcard/> and data from the International Assessment Database: Organisation for Economic Co-operation and Development (OECD) <https://www.oecd.org/>, including Programme for International Student Assessment (PISA), Teaching and Learning International Survey (TALIS), Programme for the International Assessment of Adult Competencies (PIAAC), and International Association for the Evaluation of Educational Achievement (IEA) <https://www.iea.nl/>, including Trends in International Mathematics and Science Study (TIMSS), TIMSS Advanced, Progress in International Reading Literacy Study (PIRLS), International Civic and Citizenship Study (ICCS), International Computer and Information Literacy Study (ICILS), and Civic Education Study (CivEd).

This package provides functions for signal detection and identification designed for Event-Related Potentials (ERP) data in a linear model framework. The functional F-test proposed in Causeur, Sheu, Perthame, Rufini (2018, submitted) for analysis of variance issues in ERP designs is implemented for signal detection (tests for mean difference among groups of curves in One-way ANOVA designs for example). Once an experimental effect is declared significant, identification of significant intervals is achieved by the multiple testing procedures reviewed and compared in Sheu, Perthame, Lee and Causeur (2016, <DOI:10.1214/15-AOAS888>). Some of the methods gathered in the package are the classical FDR- and FWER-controlling procedures, also available using function p.adjust. The package also implements the Guthrie-Buchwald procedure (Guthrie and Buchwald, 1991 <DOI:10.1111/j.1469-8986.1991.tb00417.x>), which accounts for the auto-correlation among t-tests to control erroneous detection of short intervals. The Adaptive Factor-Adjustment method is an extension of the method described in Causeur, Chu, Hsieh and Sheu (2012, <DOI:10.3758/s13428-012-0230-0>). It assumes a factor model for the correlation among tests and combines adaptively the estimation of the signal and the updating of the dependence modelling (see Sheu et al., 2016, <DOI:10.1214/15-AOAS888> for further details).

Three semi-parametric methods for detection of outliers in environmental data based on kernel regression and subsequent analysis of smoothing residuals. The first method (Campulova, Michalek, Mikuska and Bokal (2018) <DOI: 10.1002/cem.2997>) analyzes the residuals using changepoint analysis, the second method is based on control charts (Campulova, Veselik and Michalek (2017) <DOI: 10.1016/j.apr.2017.01.004>) and the third method (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>) analyzes the residuals using extreme value theory (Holesovsky, Campulova and Michalek (2018) <DOI: 10.1016/j.apr.2017.06.005>).

This package implements several algorithms for bundling edges in networks and flow and metro map layouts. This includes force directed edge bundling <doi:10.1111/j.1467-8659.2009.01450.x>, a flow algorithm based on Steiner trees<doi:10.1080/15230406.2018.1437359> and a multicriteria optimization method for metro map layouts <doi:10.1109/TVCG.2010.24>.

Support ecological analyses such as ordination and clustering. Contains consistent and easy wrapper functions of stat', vegan', and labdsv packages, and visualisation functions of ordination and clustering.

This package provides functions for computing test reliability and conditional standard error of measurement (CSEM) based on the methods described in the Reliability in Educational Measurement chapter of the 5th edition of "Educational Measurement" by Lee and Harris (2025, ISBN:9780197654965).

This package implements the exponential Factor Copula Model (eFCM) of Castro-Camilo, D. and Huser, R. (2020) for spatial extremes, with tools for dependence estimation, tail inference, and visualization. The package supports likelihood-based inference, Gaussian process modeling via Matérn covariance functions, and bootstrap uncertainty quantification. See Castro-Camilo and Huser (2020) <doi:10.1080/01621459.2019.1647842>.

Open source data allows for reproducible research and helps advance our knowledge. The purpose of this package is to collate open source ophthalmic data sets curated for direct use. This is real life data of people with intravitreal injections with anti-vascular endothelial growth factor (anti-VEGF), due to age-related macular degeneration or diabetic macular edema. Associated publications of the data sets: Fu et al. (2020) <doi:10.1001/jamaophthalmol.2020.5044>, Moraes et al (2020) <doi:10.1016/j.ophtha.2020.09.025>, Fasler et al. (2019) <doi:10.1136/bmjopen-2018-027441>, Arpa et al. (2020) <doi:10.1136/bjophthalmol-2020-317161>, Kern et al. 2020, <doi:10.1038/s41433-020-1048-0>.

Exploratory and descriptive analysis of event based data. Provides methods for describing and selecting process data, and for preparing event log data for process mining. Builds on the S3-class for event logs implemented in the package bupaR'.

This package provides functions supporting the reading and parsing of internal e-book content from EPUB files. The epubr package provides functions supporting the reading and parsing of internal e-book content from EPUB files. E-book metadata and text content are parsed separately and joined together in a tidy, nested tibble data frame. E-book formatting is not completely standardized across all literature. It can be challenging to curate parsed e-book content across an arbitrary collection of e-books perfectly and in completely general form, to yield a singular, consistently formatted output. Many EPUB files do not even contain all the same pieces of information in their respective metadata. EPUB file parsing functionality in this package is intended for relatively general application to arbitrary EPUB e-books. However, poorly formatted e-books or e-books with highly uncommon formatting may not work with this package. There may even be cases where an EPUB file has DRM or some other property that makes it impossible to read with epubr'. Text is read as is for the most part. The only nominal changes are minor substitutions, for example curly quotes changed to straight quotes. Substantive changes are expected to be performed subsequently by the user as part of their text analysis. Additional text cleaning can be performed at the user's discretion, such as with functions from packages like tm or qdap'.

This package provides functions to perform exploratory factor analysis (EFA) procedures and compare their solutions. The goal is to provide state-of-the-art factor retention methods and a high degree of flexibility in the EFA procedures. This way, for example, implementations from R psych and SPSS can be compared. Moreover, functions for Schmid-Leiman transformation and the computation of omegas are provided. To speed up the analyses, some of the iterative procedures, like principal axis factoring (PAF), are implemented in C++.

Allows to calculate the probabilities of occurrences of an event in a great number of repetitions of Bernoulli experiment, through the application of the local and the integral theorem of De Moivre Laplace, and the theorem of Poisson. Gives the possibility to show the results graphically and analytically, and to compare the results obtained by the application of the above theorems with those calculated by the direct application of the Binomial formula. Is basically useful for educational purposes.

This package provides statistical and visualization tools for the analysis of demographic indicators, and spatio-temporal behavior and characterization of outbreaks of vector-borne diseases (VBDs) in Colombia. It implements travel times estimated in Bravo-Vega C., Santos-Vega M., & Cordovez J.M. (2022), and the endemic channel method (Bortman, M. (1999) <https://iris.paho.org/handle/10665.2/8562>).