Package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). This is an implementation of the BRAIN algorithm described in the paper by J. Claesen, P. Dittwald, T. Burzykowski and D. Valkenborg.
Optimized XML (Ox) is a fast XML parser and object serializer for Ruby written as a native C extension. It was designed to be an alternative to Nokogiri and other Ruby XML parsers for generic XML parsing and as an alternative to Marshal for Object serialization.
This package contains many functions useful for data analysis, high-level graphics, utility operations, functions for computing sample size and power, importing and annotating datasets, imputing missing values, advanced table making, variable clustering, character string manipulation, conversion of R objects to LaTeX code, and recoding variables.
Sensitivity (or recall or true positive rate), false positive rate, specificity, precision (or positive predictive value), negative predictive value, misclassification rate, accuracy, F-score---these are popular metrics for assessing performance of binary classifiers for certain thresholds. These metrics are calculated at certain threshold values. Receiver operating characteristic (ROC) curve is a common tool for assessing overall diagnostic ability of the binary classifier. Unlike depending on a certain threshold, area under ROC curve (also known as AUC), is a summary statistic about how well a binary classifier performs overall for the classification task. The ROCit package provides flexibility to easily evaluate threshold-bound metrics.
As an advanced approach to computerized adaptive testing (CAT), shadow testing (van der Linden(2005) <doi:10.1007/0-387-29054-0>) dynamically assembles entire shadow tests as a part of selecting items throughout the testing process. Selecting items from shadow tests guarantees the compliance of all content constraints defined by the blueprint. RSCAT is an R package for the shadow-test approach to CAT. The objective of RSCAT is twofold: 1) Enhancing the effectiveness of shadow-test CAT simulation; 2) Contributing to the academic and scientific community for CAT research. RSCAT is currently designed for dichotomous items based on the three-parameter logistic (3PL) model.
This package provides a framework for estimating ensembles of parametric survival models with different parametric families. The RoBSA framework uses Bayesian model-averaging to combine the competing parametric survival models into a model ensemble, weights the posterior parameter distributions based on posterior model probabilities and uses Bayes factors to test for the presence or absence of the individual predictors or preference for a parametric family (Bartoš, Aust & Haaf, 2022, <doi:10.1186/s12874-022-01676-9>). The user can define a wide range of informative priors for all parameters of interest. The package provides convenient functions for summary, visualizations, fit diagnostics, and prior distribution calibration.
This package provides a collection of functions to simulate dice rolls and the like. In particular, experiments and exercises can be performed looking at combinations and permutations of values in dice rolls and coin flips, together with the corresponding frequencies of occurrences. When applying each function, the user has to input the number of times (rolls, flips) to toss the dice. Needless to say, the more the tosses, the more the frequencies approximate the actual probabilities. Moreover, the package provides functions to generate non-transitive sets of dice (like Efron's) and to check whether a given set of dice is non-transitive with given probability.
Makes difficult operations easy. Includes these types of functions: shorthand, type conversion, data wrangling, and work flow. Also includes some helpful data objects: NA strings, U.S. state list, color blind charting colors. Built and shared by Oliver Wyman Actuarial Consulting. Accepting proposed contributions through GitHub.
This package provides algorithms to fit linear regression models under several popular penalization techniques and functional linear regression models based on Majorizing-Minimizing (MM) and Alternating Direction Method of Multipliers (ADMM) techniques. See Boyd et al (2010) <doi:10.1561/2200000016> for complete introduction to the method.
Read and process a large delimited file block by block. A block consists of all the contiguous rows that have the same value in the first field. The result can be returned as a list or a data.table, or even directly printed to an output file.
It contains a function designed to the joint segmentation in the mean of several correlated series. The method is described in the paper X. Collilieux, E. Lebarbier and S. Robin. A factor model approach for the joint segmentation with between-series correlation (2015) <arXiv:1505.05660>.
We explore sparsity and homogeneity of regression coefficients incorporating prior constraint information. A general pairwise fusion approach is proposed to deal with the sparsity and homogeneity detection when combining prior convex constraints. We develop an modified alternating direction method of multipliers algorithm (ADMM) to obtain the estimators.
An implementation of the initial guided analytics for parameter testing and controlband extraction framework. Functions are available for continuous and categorical target variables as well as for generating standardized reports of the conducted analysis. See <https://github.com/stefan-stein/igate> for more information on the technology.
Back-end connections to LattE (<https://www.math.ucdavis.edu/~latte>) for counting lattice points and integration inside convex polytopes and 4ti2 (<http://www.4ti2.de/>) for algebraic, geometric, and combinatorial problems on linear spaces and front-end tools facilitating their use in the R ecosystem.
Use a glmmkin class object (GMMAT package) from the null model to perform generalized linear mixed model-based single-variant and variant set main effect tests, gene-environment interaction tests, and joint tests for association, as proposed in Wang et al. (2020) <DOI:10.1002/gepi.22351>.
Penalized orthogonal-components regression (POCRE) is a supervised dimension reduction method for high-dimensional data. It sequentially constructs orthogonal components (with selected features) which are maximally correlated to the response residuals. POCRE can also construct common components for multiple responses and thus build up latent-variable models.
This package provides a collection of statistical hypothesis tests of functional time series. While it will include more tests when the related literature are enriched, this package contains the following key tests: functional stationarity test, functional trend stationarity test, functional unit root test, to name a few.
SMAHP (pronounced as SOO-MAP) is a novel multi-omics framework for causal mediation analysis of high-dimensional proteogenomic data with survival outcomes. The full methodological details can be found in our recent preprint by Ahn S et al. (2025) <doi:10.48550/arXiv.2503.08606>.
This package provides tools for estimating and inferring two-way partial area under receiver operating characteristic curves (two-way pAUC), partial area under receiver operating characteristic curves (pAUC), and partial area under ordinal dominance curves (pODC). Methods includes Mann-Whitney statistic and Jackknife, etc.
This Package utilizes a Semi-parametric Differential Abundance/expression analysis (SDA) method for metabolomics and proteomics data from mass spectrometry as well as single-cell RNA sequencing data. SDA is able to robustly handle non-normally distributed data and provides a clear quantification of the effect size.
The ASAFE package contains a collection of functions that can be used to carry out an EM (Expectation–maximization) algorithm to estimate ancestry-specific allele frequencies for a bi-allelic genetic marker, e.g. an SNP (single nucleotide polymorphism) from genotypes and ancestry pairs.
This package facilitates motif analysis using MEME Suite tools. Memes provides data aware utilities for using GRanges objects as entrypoints to motifanalysis, data structures for examining & editing motif lists, and novel data visualizations. Memes functions and data structures are amenable to both base R and tidyverse workflows.
This package provides an interface to Keras, a high-level neural networks API. Keras was developed with a focus on enabling fast experimentation, supports both convolution based networks and recurrent networks (as well as combinations of the two), and runs seamlessly on both CPU and GPU devices.
The SciViews svGUI package eases the management of Graphical User Interfaces (GUI) in R. It is independent from any particular GUI widgets. It centralizes info about GUI elements currently used, and it dispatches GUI calls to the particular toolkits in use in function of the context.