The mime-types library provides a library and registry for information about Multipurpose Internet Mail Extensions (MIME) content type definitions. It can be used to determine defined filename extensions for MIME types, or to use filename extensions to look up the likely MIME type definitions.

git filter-repo is a versatile tool for rewriting history, which roughly falls into the same space of tool like git filter-branch but with more capabilities. git filter-repo is now recommended by the Git project instead of git filter-branch.

PhantasusLite – a lightweight package with helper functions of general interest extracted from phantasus package. In parituclar it simplifies working with public RNA-seq datasets from GEO by providing access to the remote HSDS repository with the precomputed gene counts from ARCHS4 and DEE2 projects.

Builds platform design information packages. These consist of a SQLite database containing feature-level data such as x, y position on chip and featureSet ID. The database also incorporates featureSet-level annotation data. The products of this packages are used by the oligo pkg.

Leverage the existing open access TCGA data on Terra with well-established Bioconductor infrastructure. Make use of the Terra data model without learning its complexities. With a few functions, you can copy / download and generate a MultiAssayExperiment from the TCGA example workspaces provided by Terra.

The httpclient ruby library provides functionality related to HTTP. Compared to the net/http library, httpclient also provides Cookie, multithreading and authentication (digest, NTLM) support.

Also provided is a httpclient command, which can perform HTTP requests either using arguments or with an interactive prompt.

This package provides RangedSummarizedExperiment objects of read counts in genes and exonic parts for paired-end RNA-Seq data from experiments on primary cultures of parathyroid tumors. The sequencing was performed on tumor cultures from 4 patients at 2 time points over 3 conditions (DPN, OHT and control).

This package provides methods to convert between Python AnnData objects and SingleCellExperiment objects. These are primarily intended for use by downstream Bioconductor packages that wrap Python methods for single-cell data analysis. It also includes functions to read and write H5AD files used for saving AnnData objects to disk.

This package provides a major mode for editing Rego file (See https://www.openpolicyagent.org/docs/latest/policy-language/ to learn more) in Emacs. Some of its major features include: - syntax highlighting (font lock), - Basic indentation, raw and normal string support - Automatic formatting on save (configurable) - REPL support

This is a framework for fitting multiple caret models. It uses the same re-sampling strategy as well as creating ensembles of such models. Use caretList to fit multiple models and then use caretEnsemble to combine them greedily or caretStack to combine them using a caret model.

Fit Conway-Maxwell Poisson (COM-Poisson or CMP) regression models to count data (Sellers & Shmueli, 2010) <doi:10.1214/09-AOAS306>. The package provides functions for model estimation, dispersion testing, and diagnostics. Zero-inflated CMP regression (Sellers & Raim, 2016) <doi:10.1016/j.csda.2016.01.007> is also supported.

This is a package for saving SingleCellExperiment into file artifacts, and loading them back into memory. This is a more portable alternative to serialization of such objects into RDS files. Each artifact is associated with metadata for further interpretation; downstream applications can enrich this metadata with context-specific properties.

This package provides tools to efficiently represent and manipulate genomic annotations and alignments is playing a central role when it comes to analyzing high-throughput sequencing data (a.k.a. NGS data). The GenomicRanges package defines general purpose containers for storing and manipulating genomic intervals and variables defined along a genome.

This package improves and replaces the GNU Emacs commands that interactively evaluate Emacs Lisp expressions. The new commands replace standard key bindings and are all prefixed with rsw-elisp-. They work the same way as the old commands when called non-interactively; only the interactive behavior should be different.

This package adds the ability to run tests by filtering the test tree based on the result of a previous test run. You can use this to run only those tests that failed in the last run, or to only run the tests that have been added since previous test run.

The test-queue module is a parallel test runner, built using a centralized queue to ensure optimal distribution of tests between workers. It is specifically optimized for Continuous Integration (CI) environments: build statistics from each run are stored locally and used to sort the queue at the beginning of the next run.

This package provides an easy to use command. It takes an URL of the Research Organization Registry (ROR) as argument and creates a ROR symbol which links to the given URL---very similar to the orcidlink package from which it is derived. The symbol itself always fits with the chosen font size.

omicRexposome systematizes the association evaluation between exposures and omic data, taking advantage of MultiDataSet for coordinated data management, rexposome for exposome data definition and limma for association testing. Also to perform data integration mixing exposome and omic data using multi co-inherent analysis (omicade4) and multi-canonical correlation analysis (PMA).

This package provides a client for the Bioconductor ExperimentHub web resource. ExperimentHub provides a central location where curated data from experiments, publications or training courses can be accessed. Each resource has associated metadata, tags and date of modification. The client creates and manages a local cache of files retrieved enabling quick and reproducible access.

MetagenomeSeq is designed to determine features (be it OTU, species, etc.) that are differentially abundant between two or more groups of multiple samples. This package is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations.

The *MungeSumstats* package is designed to facilitate the standardisation of GWAS summary statistics. It reformats inputted summary statisitics to include SNP, CHR, BP and can look up these values if any are missing. It also pefrorms dozens of QC and filtering steps to ensure high data quality and minimise inter-study differences.

QLTExperiment defines an S4 class for storing and manipulating summary statistics from QTL mapping experiments in one or more states. It is based on the SummarizedExperiment class and contains functions for creating, merging, and subsetting objects. QTLExperiment also stores experiment metadata and has checks in place to ensure that transformations apply correctly.

This package can be used to conduct post hoc analyses of resampling results generated by models. For example, if two models are evaluated with the root mean squared error (RMSE) using 10-fold cross-validation, there are 10 paired statistics. These can be used to make comparisons between models without involving a test set.

This package provides a collection of functions that perform operations on time-series accelerometer data, such as identify the non-wear time, flag minutes that are part of an activity bout, and find the maximum 10-minute average count value. The functions are generally very flexible, allowing for a variety of algorithms to be implemented.